full name
mucin 5B, oligomeric mucus/gel-forming

synonyms
MG1, MUC-5B, MUC5, MUC9, MUC5B, ENSG00000117983

HGNC
HGNC:7516

Entrez Gene
Gene:727897

ENSEMBL
ENSG00000117983

location
chr: 11
start: 1244295
stop: 1283406
strand: +

OMIM
OMIM:600770: MUC5B
OMIM:178500: {Pulmonary fibrosis, idiopathic, susceptibility to}

transcripts
NM_002458.2

pathways
C-type lectin receptors (CLRs) [NCBI:1269303] [REACTOME:R-HSA-5621481] [PUBMED:19521399] [PUBMED:24330199]
Dectin-2 family [NCBI:1269308] [REACTOME:R-HSA-5621480] [PUBMED:19521399] [PUBMED:19665392] [PUBMED:23606632]
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) [NCBI:1383050] [REACTOME:R-HSA-5083632] [PUBMED:24643043] [PUBMED:18537974]
Defective GALNT12 causes colorectal cancer 1 (CRCS1) [NCBI:1383052] [REACTOME:R-HSA-5083636] [PUBMED:12135769] [PUBMED:19617566] [PUBMED:22183981] [PUBMED:22461326] [PUBMED:9394011] [PUBMED:9295285]
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) [NCBI:1383051] [REACTOME:R-HSA-5083625] [PUBMED:9295285] [PUBMED:15687324] [PUBMED:9394011] [PUBMED:15599692] [PUBMED:16151858] [PUBMED:22183981]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases associated with O-glycosylation of proteins [NCBI:1383049] [REACTOME:R-HSA-3906995] [PUBMED:24051442] [PUBMED:24507773]
Diseases of glycosylation [NCBI:1269010] [REACTOME:R-HSA-3781865] [PUBMED:22983739] [PUBMED:12756558] [PUBMED:22343051] [PUBMED:6543331] [PUBMED:16755287] [PUBMED:19765534] [PUBMED:12409504] [PUBMED:22838182] [PUBMED:2301971] [PUBMED:21384229]
IL-17 signaling pathway [NCBI:1474301] [KEGG:hsa04657] [PUBMED:17921324] [PUBMED:24011563] [PUBMED:21349428] [PUBMED:20383173] [PUBMED:20514051] [PUBMED:20177959] [PUBMED:18178098] [PUBMED:21074482] [PUBMED:21130872] [PUBMED:17027518] [PUBMED:23917206] [PUBMED:23116200] [PUBMED:18701318] [PUBMED:26252407] [PUBMED:22851696] [PUBMED:21155836] [PUBMED:25145755] [PUBMED:17177681] [PUBMED:19575028] [PUBMED:23557798] [PUBMED:21852080] [PUBMED:22324470]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
O-linked glycosylation [NCBI:1268734] [REACTOME:R-HSA-5173105] [PUBMED:9673446] [PUBMED:22722607]
O-linked glycosylation of mucins [NCBI:1268736] [REACTOME:R-HSA-913709] [PUBMED:20301232] [PUBMED:17988798]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Salivary secretion [NCBI:153376] [KEGG:hsa04970] [PUBMED:8105741] [PUBMED:10682899] [PUBMED:10928320] [PUBMED:15709965] [PUBMED:17347411] [PUBMED:9720759] [PUBMED:16712780] [PUBMED:16799262] [PUBMED:17157080] [PUBMED:18626068] [PUBMED:15153696] [PUBMED:11936453] [PUBMED:20224180]
Termination of O-glycan biosynthesis [NCBI:1268737] [REACTOME:R-HSA-977068] [PUBMED:20301246]