full name
hemoglobin subunit beta

synonyms
beta-globin, CD113t-C, HBB, ENSG00000244734

HGNC
HGNC:4827

Entrez Gene
Gene:3043

ENSEMBL
ENSG00000244734

location
chr: 11
start: 5246696
stop: 5248301
strand: -

OMIM
OMIM:141900: HBB (Autosomal dominant inheritance)
OMIM:141749: Delta-beta thalassemia
OMIM:140700: Heinz body anemias, beta-
OMIM:141749: Hereditary persistence of fetal hemoglobin
OMIM:603903: Sickle cell anemia
OMIM:603902: Thalassemia-beta, dominant inclusion-body
OMIM:613985: Thalassemias, beta-
OMIM:611162: {Malaria, resistance to}

transcripts
NM_000518.4

pathways
African trypanosomiasis [NCBI:194384] [KEGG:hsa05143] [PUBMED:9574925] [PUBMED:12088284] [PUBMED:19559585] [PUBMED:20398209] [PUBMED:17582444] [PUBMED:19168735] [PUBMED:19016378] [PUBMED:11850009] [PUBMED:16600243] [PUBMED:19995590] [PUBMED:19621073]
Binding and Uptake of Ligands by Scavenger Receptors [NCBI:1269897] [REACTOME:R-HSA-2173782] [PUBMED:16511968] [PUBMED:15904923] [PUBMED:218198] [PUBMED:19388903] [PUBMED:19659436]
Erythrocytes take up carbon dioxide and release oxygen [NCBI:1270224] [REACTOME:R-HSA-1237044] [PUBMED:19879980] [PUBMED:15491402] [PUBMED:10747205]
Erythrocytes take up oxygen and release carbon dioxide [NCBI:1270225] [REACTOME:R-HSA-1247673] [PUBMED:15491402] [PUBMED:19879980] [PUBMED:16679072]
Factors involved in megakaryocyte development and platelet production [NCBI:1269377] [REACTOME:R-HSA-983231] [PUBMED:16856888] [PUBMED:17635743] [PUBMED:17934486]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Malaria [NCBI:152665] [KEGG:hsa05144] [PUBMED:15106591] [PUBMED:11224682] [PUBMED:17630968] [PUBMED:18250459] [PUBMED:16138104] [PUBMED:20091081] [PUBMED:8920859] [PUBMED:19101208] [PUBMED:16019257] [PUBMED:15464448] [PUBMED:11832955] [PUBMED:12364790] [PUBMED:10885986] [PUBMED:15094163] [PUBMED:14737184] [PUBMED:15463497] [PUBMED:16468982] [PUBMED:19967139]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
O2/CO2 exchange in erythrocytes [NCBI:1270223] [REACTOME:R-HSA-1480926] [PUBMED:9050246] [PUBMED:10747205] [PUBMED:19879980] [PUBMED:15491402] [PUBMED:16679072] [PUBMED:17573207]
Scavenging of heme from plasma [NCBI:1269898] [REACTOME:R-HSA-2168880] [PUBMED:19659436] [PUBMED:19650691] [PUBMED:16511968] [PUBMED:12042069] [PUBMED:2485589] [PUBMED:11865982] [PUBMED:19659435]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]