full name
tripeptidyl peptidase 1

synonyms
CLN2, GIG1, LPIC, TPP-1, TPP1, ENSG00000166340

HGNC
HGNC:2073

Entrez Gene
Gene:1200

ENSEMBL
ENSG00000166340

location
chr: 11
start: 6633997
stop: 6640692
strand: -

OMIM
OMIM:607998: TPP1 (Autosomal recessive inheritance)
OMIM:204500: Ceroid lipofuscinosis, neuronal, 2
OMIM:609270: Spinocerebellar ataxia, autosomal recessive 7

transcripts
NM_000391.3

pathways
IRE1alpha activates chaperones [NCBI:1268759] [REACTOME:R-HSA-381070] [PUBMED:18048764] [PUBMED:18038217] [PUBMED:18436705]
Lysosome [NCBI:99052] [KEGG:hsa04142] [PUBMED:2943218] [PUBMED:12628346] [PUBMED:1883197] [PUBMED:18635948] [PUBMED:15987739]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Unfolded Protein Response (UPR) [NCBI:1268756] [REACTOME:R-HSA-381119] [PUBMED:18436705] [PUBMED:18038217] [PUBMED:27067637] [PUBMED:16365312] [PUBMED:18048764] [PUBMED:15952902]
XBP1(S) activates chaperone genes [NCBI:1268760] [REACTOME:R-HSA-381038] [PUBMED:16461360] [PUBMED:16539657] [PUBMED:17612490] [PUBMED:14559994] [PUBMED:18664523]