full name
MCL1, BCL2 family apoptosis regulator
synonyms
bcl2-L-3, BCL2L3, EAT, Mcl-1, MCL1-ES, mcl1%2FEAT, MCL1L, MCL1S, TM, MCL1, ENSG00000143384
HGNC
HGNC:6943
Entrez Gene
Gene:4170
ENSEMBL
ENSG00000143384
location
chr: 1
start: 150547027
stop: 150552214
strand: -
transcripts
NM_001197320.1
NM_182763.2
NM_021960.4
pathways
Apoptosis
[NCBI:83060]
[KEGG:hsa04210]
[NCBI:1270262]
[REACTOME:R-HSA-109581]
[PUBMED:12189384]
[PUBMED:20533903]
[PUBMED:18208375]
[PUBMED:22429822]
[PUBMED:15218528]
[PUBMED:24769728]
[PUBMED:18023214]
[PUBMED:25526085]
[PUBMED:23070002]
[PUBMED:15654015]
[PUBMED:15601572]
[PUBMED:14561771]
[PUBMED:24278747]
[PUBMED:21914490]
[PUBMED:22465226]
[PUBMED:21145844]
[PUBMED:12838338]
[PUBMED:18238895]
[PUBMED:12949498]
[PUBMED:18304445]
[PUBMED:14737178]
[PUBMED:26231733]
[PUBMED:9916983]
[PUBMED:14634621]
[PUBMED:19770840]
[PUBMED:22075987]
[PUBMED:4561027]
[PUBMED:20075940]
[PUBMED:9894605]
[PUBMED:26615431]
[PUBMED:12505355]
[PUBMED:11520933]
[PUBMED:19148180]
[PUBMED:16397578]
[PUBMED:15719025]
[PUBMED:15322527]
[PUBMED:15725726]
[PUBMED:12209154]
[PUBMED:23803157]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Direct p53 effectors
[NCBI:137939]
[Pathway Interaction Database:p53downstreampathway]
[PUBMED:7479001]
[PUBMED:19626115]
[PUBMED:10692390]
[PUBMED:15289308]
[PUBMED:14688482]
[PUBMED:16301995]
[PUBMED:11850816]
[PUBMED:12370809]
[PUBMED:16260627]
[PUBMED:15186775]
[PUBMED:15580302]
[PUBMED:10748162]
[PUBMED:10919640]
[PUBMED:19011621]
[PUBMED:12438652]
[PUBMED:11559530]
[PUBMED:11641774]
[PUBMED:11971958]
[PUBMED:9659898]
[PUBMED:9343394]
[PUBMED:10716435]
[PUBMED:17146433]
[PUBMED:17719542]
[PUBMED:17938176]
[PUBMED:17409421]
[PUBMED:11032029]
[PUBMED:15781865]
[PUBMED:11463392]
[PUBMED:9736732]
[PUBMED:17268548]
[PUBMED:8570655]
[PUBMED:18046411]
[PUBMED:12944906]
[PUBMED:16249378]
[PUBMED:15273740]
[PUBMED:15598651]
[PUBMED:10618379]
[PUBMED:15958553]
[PUBMED:17189187]
[PUBMED:17145718]
[PUBMED:11988847]
[PUBMED:8119988]
[PUBMED:12089322]
[PUBMED:16286009]
[PUBMED:12890671]
[PUBMED:12402042]
[PUBMED:10618714]
[PUBMED:14730312]
[PUBMED:12857899]
[PUBMED:14963330]
[PUBMED:11278953]
[PUBMED:11973653]
[PUBMED:12692263]
[PUBMED:10984493]
[PUBMED:10640990]
[PUBMED:11545734]
[PUBMED:16151013]
[PUBMED:12372430]
[PUBMED:16651407]
[PUBMED:9891062]
[PUBMED:12606722]
[PUBMED:12453409]
[PUBMED:15377670]
[PUBMED:12667443]
[PUBMED:17707234]
[PUBMED:9920903]
[PUBMED:14992722]
[PUBMED:15790310]
[PUBMED:15831478]
[PUBMED:11314010]
[PUBMED:10329733]
[PUBMED:17264218]
[PUBMED:11511362]
[PUBMED:11919562]
[PUBMED:11814693]
[PUBMED:17554199]
[PUBMED:18250150]
[PUBMED:10518217]
[PUBMED:10891498]
[PUBMED:10973264]
[PUBMED:15077116]
[PUBMED:16230375]
[PUBMED:18485870]
[PUBMED:7796420]
[PUBMED:15710382]
[PUBMED:17409411]
[PUBMED:8319905]
[PUBMED:10684646]
[PUBMED:7566179]
[PUBMED:8887630]
[PUBMED:11807984]
[PUBMED:9841917]
[PUBMED:12654245]
[PUBMED:9023107]
[PUBMED:15103385]
[PUBMED:11684014]
[PUBMED:17110336]
[PUBMED:11278253]
[PUBMED:14576823]
[PUBMED:8418500]
[PUBMED:11350971]
[PUBMED:11840333]
[PUBMED:7651818]
[PUBMED:7651386]
[PUBMED:15378026]
[PUBMED:15607964]
[PUBMED:11279192]
[PUBMED:10777218]
[PUBMED:15334053]
[PUBMED:12138177]
[PUBMED:9619826]
[PUBMED:16278683]
[PUBMED:17189186]
[PUBMED:16140933]
[PUBMED:10094469]
[PUBMED:9926927]
[PUBMED:17719541]
[PUBMED:15735003]
[PUBMED:12853982]
[PUBMED:14707288]
[PUBMED:10777207]
E2F transcription factor network
[NCBI:137934]
[Pathway Interaction Database:e2f_pathway]
[PUBMED:15175242]
[PUBMED:11034215]
[PUBMED:8832394]
[PUBMED:7479977]
[PUBMED:12077144]
[PUBMED:11274364]
[PUBMED:8618861]
[PUBMED:11857079]
[PUBMED:7958837]
[PUBMED:15014447]
[PUBMED:9774682]
[PUBMED:9704927]
[PUBMED:9271400]
[PUBMED:8334989]
[PUBMED:16288221]
[PUBMED:10766737]
[PUBMED:8657141]
[PUBMED:8552092]
[PUBMED:11101847]
[PUBMED:12757710]
[PUBMED:17704056]
[PUBMED:7705662]
[PUBMED:15897886]
[PUBMED:9192872]
[PUBMED:9778043]
[PUBMED:12766778]
[PUBMED:15510213]
[PUBMED:11418595]
[PUBMED:10454584]
[PUBMED:10783242]
[PUBMED:11904439]
[PUBMED:16179649]
[PUBMED:7791762]
[PUBMED:11719808]
[PUBMED:12389032]
[PUBMED:8264596]
[PUBMED:19491197]
[PUBMED:15713665]
[PUBMED:16357170]
[PUBMED:9689056]
[PUBMED:12748276]
[PUBMED:2524830]
[PUBMED:14633988]
[PUBMED:12697828]
[PUBMED:12101096]
[PUBMED:11799067]
[PUBMED:15133492]
[PUBMED:16892051]
[PUBMED:8943353]
[PUBMED:9724731]
[PUBMED:10030670]
[PUBMED:11459832]
[PUBMED:8114719]
[PUBMED:9520412]
[PUBMED:18348985]
[PUBMED:9020173]
[PUBMED:11389439]
[PUBMED:16211008]
[PUBMED:12411495]
[PUBMED:7958836]
[PUBMED:12909625]
[PUBMED:15306814]
[PUBMED:10688648]
[PUBMED:12611887]
[PUBMED:9191053]
[PUBMED:10373518]
[PUBMED:10187822]
HIF-1-alpha transcription factor network
[NCBI:138045]
[Pathway Interaction Database:hif1_tfpathway]
[PUBMED:11707426]
[PUBMED:9242677]
[PUBMED:9038135]
[PUBMED:15310764]
[PUBMED:11278891]
[PUBMED:8816435]
[PUBMED:8663540]
[PUBMED:15235127]
[PUBMED:12042299]
[PUBMED:15312748]
[PUBMED:14612449]
[PUBMED:11342587]
[PUBMED:12615703]
[PUBMED:9632793]
[PUBMED:12228247]
[PUBMED:15044468]
[PUBMED:8408001]
[PUBMED:9822602]
[PUBMED:15252039]
[PUBMED:13679920]
[PUBMED:11877282]
[PUBMED:15235597]
[PUBMED:15199161]
[PUBMED:15104534]
[PUBMED:10594042]
[PUBMED:12354771]
[PUBMED:10446188]
[PUBMED:9436976]
[PUBMED:11823643]
[PUBMED:12370277]
[PUBMED:8955077]
[PUBMED:12879018]
[PUBMED:14645546]
[PUBMED:9486205]
[PUBMED:9887100]
[PUBMED:8089148]
[PUBMED:15466858]
[PUBMED:11708773]
[PUBMED:15611046]
[PUBMED:14742449]
[PUBMED:15280364]
[PUBMED:12215445]
[PUBMED:15611089]
[PUBMED:10777486]
[PUBMED:9707622]
[PUBMED:8917528]
[PUBMED:15563275]
[PUBMED:12067980]
[PUBMED:10353251]
IL6-mediated signaling events
[NCBI:137932]
[Pathway Interaction Database:il6_7pathway]
[PUBMED:8559663]
[PUBMED:8662591]
[PUBMED:11689697]
[PUBMED:11727828]
[PUBMED:10383440]
[PUBMED:10777583]
[PUBMED:16774741]
[PUBMED:12754507]
[PUBMED:9295319]
[PUBMED:15722452]
[PUBMED:10859312]
[PUBMED:9590172]
[PUBMED:9880505]
[PUBMED:12445202]
[PUBMED:8134389]
[PUBMED:10409724]
[PUBMED:8164674]
[PUBMED:8272872]
[PUBMED:9794795]
[PUBMED:7678052]
[PUBMED:8511589]
[PUBMED:8668165]
[PUBMED:9724754]
[PUBMED:8083235]
[PUBMED:12754505]
[PUBMED:8621622]
[PUBMED:16254248]
[PUBMED:12361954]
[PUBMED:10605021]
[PUBMED:9388184]
[PUBMED:15935617]
[PUBMED:11120832]
[PUBMED:7875298]
[PUBMED:9973404]
[PUBMED:11335711]
[PUBMED:9632795]
[PUBMED:11468294]
[PUBMED:7898939]
[PUBMED:8626374]
[PUBMED:8670868]
[PUBMED:7537214]
[PUBMED:15677447]
[PUBMED:2261637]
[PUBMED:9874564]
[PUBMED:12829785]
[PUBMED:8537375]
[PUBMED:8272873]
[PUBMED:7523403]
[PUBMED:11251120]
[PUBMED:9163525]
[PUBMED:3136546]
[PUBMED:10727406]
[PUBMED:10023775]
[PUBMED:12754506]
[PUBMED:12456685]
[PUBMED:2788034]
[PUBMED:10446219]
[PUBMED:15572665]
[PUBMED:1662392]
[PUBMED:15010462]
[PUBMED:8140422]
[PUBMED:8467812]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Interleukin-4 and 13 signaling
[NCBI:1470923]
[REACTOME:R-HSA-6785807]
[PUBMED:12704343]
[PUBMED:10358772]
Jak-STAT signaling pathway
[NCBI:83077]
[KEGG:hsa04630]
[PUBMED:21034406]
[PUBMED:22339650]
[PUBMED:16204702]
[PUBMED:25587654]
[PUBMED:24069565]
[PUBMED:22383755]
[PUBMED:24606160]
[PUBMED:10851053]
[PUBMED:23735217]
[PUBMED:25217450]
[PUBMED:21372217]
MicroRNAs in cancer
[NCBI:852705]
[KEGG:hsa05206]
[PUBMED:23075324]
[PUBMED:21742789]
[PUBMED:22351564]
[PUBMED:18817506]
[PUBMED:22345301]
[PUBMED:21402473]
[PUBMED:22926415]
[PUBMED:23165235]
[PUBMED:19630570]
[PUBMED:21565290]
[PUBMED:23091478]
[PUBMED:23462054]
[PUBMED:23316212]
[PUBMED:19773200]
[PUBMED:22035854]
[PUBMED:20221895]
[PUBMED:20345848]
[PUBMED:22580099]
[PUBMED:20128019]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
