Logo
full name
phosphodiesterase 3B

synonyms
cGIPDE1, HcGIP1, PDE3B, ENSG00000152270

HGNC
HGNC:8779

Entrez Gene
Gene:5140

ENSEMBL
ENSG00000152270
ENSG00000261923

location
chr: 11
start: 14665191
stop: 14893605
strand: +

transcripts
NM_000922.3

pathways
Apelin signaling pathway [NCBI:1492886] [KEGG:hsa04371] [PUBMED:23973488] [PUBMED:16182514] [PUBMED:21725702] [PUBMED:22842084] [PUBMED:27825851] [PUBMED:27650065] [PUBMED:22140623] [PUBMED:23943882] [PUBMED:26944568] [PUBMED:24055369] [PUBMED:26385179] [PUBMED:26143239] [PUBMED:22028387] [PUBMED:26254105] [PUBMED:26756969] [PUBMED:22995518] [PUBMED:27979574] [PUBMED:23924696] [PUBMED:21464822] [PUBMED:25914650] [PUBMED:24990699] [PUBMED:26607438] [PUBMED:25164121] [PUBMED:25275559] [PUBMED:25139773] [PUBMED:25931124] [PUBMED:19093215] [PUBMED:20539939] [PUBMED:25652330] [PUBMED:18272138] [PUBMED:23603510]
Class IB PI3K non-lipid kinase events [NCBI:138082] [Pathway Interaction Database:pi3kcibpathway] [PUBMED:15294162] [PUBMED:9765155]
G alpha (s) signalling events [NCBI:1269575] [REACTOME:R-HSA-418555] [PUBMED:12036966]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
Glucagon signaling pathway [NCBI:1144996] [KEGG:hsa04922] [PUBMED:20735177] [PUBMED:19912989] [PUBMED:21941300] [PUBMED:22249520] [PUBMED:12626323] [PUBMED:16601267] [PUBMED:18669612] [PUBMED:24393785] [PUBMED:21346730] [PUBMED:22550228] [PUBMED:16479585] [PUBMED:24692138] [PUBMED:22495310] [PUBMED:22796337] [PUBMED:22004992] [PUBMED:24238363] [PUBMED:22503562]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
IGF1R signaling cascade [NCBI:1269618] [REACTOME:R-HSA-2428924] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959]
IRS-mediated signalling [NCBI:1269431] [REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R [NCBI:1269620] [REACTOME:R-HSA-2428928] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:18927274] [PUBMED:21042815] [PUBMED:20098959]
Insulin receptor signalling cascade [NCBI:1269429] [REACTOME:R-HSA-74751] [PUBMED:9677303] [PUBMED:11282018]
Insulin signaling pathway [NCBI:83090] [KEGG:hsa04910] [PUBMED:11742412] [PUBMED:11343120] [PUBMED:15733744] [PUBMED:11282018] [PUBMED:10196204] [PUBMED:18291668] [PUBMED:9609110] [PUBMED:10567225] [PUBMED:12791379] [PUBMED:9748166] [PUBMED:15624019] [PUBMED:9445476] [PUBMED:9346240] [PUBMED:14635525] [PUBMED:16288289] [PUBMED:12867054] [PUBMED:15229476] [PUBMED:17344645] [PUBMED:9609111]
Morphine addiction [NCBI:552665] [KEGG:hsa05032] [PUBMED:8785060] [PUBMED:16581089] [PUBMED:21872647] [PUBMED:14625081] [PUBMED:20962224] [PUBMED:15661627] [PUBMED:1346804] [PUBMED:12859419] [PUBMED:8096779] [PUBMED:18349442] [PUBMED:21930931] [PUBMED:10066284] [PUBMED:14969742] [PUBMED:8987801] [PUBMED:12217944] [PUBMED:11750924] [PUBMED:11152760]
Nitric oxide stimulates guanylate cyclase [NCBI:1269343] [REACTOME:R-HSA-392154] [PUBMED:12881475]
PDE3B signalling [NCBI:1269435] [REACTOME:R-HSA-165160]
PI3K Cascade [NCBI:1269432] [REACTOME:R-HSA-109704]
PKB-mediated events [NCBI:1269434] [REACTOME:R-HSA-109703]
Platelet homeostasis [NCBI:1269341] [REACTOME:R-HSA-418346] [PUBMED:10798271]
Progesterone-mediated oocyte maturation [NCBI:119304] [KEGG:hsa04914] [PUBMED:10497333] [PUBMED:12084906] [PUBMED:12045215] [PUBMED:11063930] [PUBMED:12477927] [PUBMED:11148128] [PUBMED:11730319] [PUBMED:12374568]
Purine metabolism [NCBI:82944] [KEGG:hsa00230] [NCBI:1270134] [REACTOME:R-HSA-73847] [PUBMED:4620886] [PUBMED:10986234] [PUBMED:10601204]
Regulation of lipolysis in adipocytes [NCBI:1222950] [KEGG:hsa04923] [PUBMED:24676492] [PUBMED:21241784] [PUBMED:17313320] [PUBMED:21900692] [PUBMED:20025992] [PUBMED:19375517] [PUBMED:22298655] [PUBMED:19464318] [PUBMED:24872083] [PUBMED:19136990] [PUBMED:19796963] [PUBMED:18762440] [PUBMED:17878492] [PUBMED:24731595] [PUBMED:17218471]
Renin secretion [NCBI:1222951] [KEGG:hsa04924] [PUBMED:24944035] [PUBMED:22733355] [PUBMED:20936939] [PUBMED:12949225] [PUBMED:17360952] [PUBMED:17928544] [PUBMED:19948673] [PUBMED:12388321] [PUBMED:15283749] [PUBMED:22237158] [PUBMED:22258323] [PUBMED:9882634] [PUBMED:20393195] [PUBMED:22124804]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Insulin receptor [NCBI:1269428] [REACTOME:R-HSA-74752] [PUBMED:8276779]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) [NCBI:1269617] [REACTOME:R-HSA-2404192] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22044904] [PUBMED:22649417]
cAMP signaling pathway [NCBI:1017634] [KEGG:hsa04024] [PUBMED:10880354] [PUBMED:9204709] [PUBMED:21693691] [PUBMED:24062645] [PUBMED:24450633] [PUBMED:21346730] [PUBMED:24613710] [PUBMED:21744067] [PUBMED:22082266] [PUBMED:16460276] [PUBMED:18176800] [PUBMED:14715909] [PUBMED:7688165] [PUBMED:24281338] [PUBMED:11117527] [PUBMED:16765984] [PUBMED:18323530] [PUBMED:18064650] [PUBMED:21852968] [PUBMED:11493633] [PUBMED:21212391] [PUBMED:15142747] [PUBMED:17077866] [PUBMED:19460777] [PUBMED:19874988] [PUBMED:16571352] [PUBMED:22022314]
cGMP effects [NCBI:1269344] [REACTOME:R-HSA-418457] [PUBMED:7913615] [PUBMED:14597579]
cGMP-PKG signaling pathway [NCBI:983748] [KEGG:hsa04022] [PUBMED:18006449] [PUBMED:9003029] [PUBMED:18040025] [PUBMED:19306895] [PUBMED:21666108] [PUBMED:12524221] [PUBMED:16460276] [PUBMED:20716671] [PUBMED:22785374] [PUBMED:11522789] [PUBMED:16439998] [PUBMED:16371594] [PUBMED:20388537] [PUBMED:18757523] [PUBMED:16815627] [PUBMED:23212367] [PUBMED:21685243] [PUBMED:20024580] [PUBMED:15894227] [PUBMED:22965426] [PUBMED:17643091] [PUBMED:19176601] [PUBMED:19961855]