full name
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

synonyms
CPK, PI3-K-C2%28ALPHA%29, PI3-K-C2A, PIK3C2A, ENSG00000011405

HGNC
HGNC:8971

Entrez Gene
Gene:5286

ENSEMBL
ENSG00000011405

location
chr: 11
start: 17108108
stop: 17229543
strand: -

OMIM
OMIM:603601: PIK3C2A
OMIM:618440: Oculoskeletodental syndrome

transcripts
NM_002645.2

pathways
3-phosphoinositide biosynthesis [NCBI:545314] [BIOCYC:HUMAN_PWY-6352] [PUBMED:9632630] [PUBMED:7798235] [PUBMED:2553693] [PUBMED:8086005] [PUBMED:9247130]
Clathrin derived vesicle budding [NCBI:1269881] [REACTOME:R-HSA-421837]
Clathrin-mediated endocytosis [NCBI:1427858] [REACTOME:R-HSA-8856828] [PUBMED:16516836] [PUBMED:15339664] [PUBMED:19754444] [PUBMED:8552632] [PUBMED:21779028] [PUBMED:12353027] [PUBMED:23891661] [PUBMED:21613550] [PUBMED:20059951] [PUBMED:21447041] [PUBMED:17620409] [PUBMED:16903783] [PUBMED:21445324] [PUBMED:19696798] [PUBMED:26246598] [PUBMED:25085911] [PUBMED:24186068] [PUBMED:26829388] [PUBMED:27092250] [PUBMED:24581490] [PUBMED:26042225] [PUBMED:23823722] [PUBMED:24789820] [PUBMED:9736607] [PUBMED:23637288] [PUBMED:22233676] [PUBMED:19458185] [PUBMED:26403691] [PUBMED:19296720] [PUBMED:15703209] [PUBMED:20428113] [PUBMED:8953040] [PUBMED:1177317] [PUBMED:9092476] [PUBMED:26872272] [PUBMED:19092055]
Golgi Associated Vesicle Biogenesis [NCBI:1269882] [REACTOME:R-HSA-432722]
Inositol phosphate metabolism [NCBI:82987] [KEGG:hsa00562] [NCBI:1269988] [REACTOME:R-HSA-1483249] [PUBMED:17943301] [PUBMED:18310071] [PUBMED:20414202] [PUBMED:11331907] [PUBMED:20359876] [PUBMED:14993306] [PUBMED:16781889]
Integrins in angiogenesis [NCBI:137999] [Pathway Interaction Database:avb3_integrin_pathway] [PUBMED:10837460] [PUBMED:9182576] [PUBMED:12642872] [PUBMED:15711558] [PUBMED:10037797] [PUBMED:10196194] [PUBMED:11877390] [PUBMED:16418218] [PUBMED:16600665] [PUBMED:16982628] [PUBMED:15479743] [PUBMED:16720645] [PUBMED:11684710] [PUBMED:10821695] [PUBMED:12237112] [PUBMED:12750158] [PUBMED:11551924] [PUBMED:8794870] [PUBMED:10022831] [PUBMED:15187087] [PUBMED:16195423] [PUBMED:16760434] [PUBMED:12682293] [PUBMED:9420328] [PUBMED:15247219] [PUBMED:9490736] [PUBMED:11313365]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
PI Metabolism [NCBI:1270073] [REACTOME:R-HSA-1483255] [PUBMED:17035995] [PUBMED:18216768] [PUBMED:17330069] [PUBMED:15170460] [PUBMED:16828287] [PUBMED:18726176] [PUBMED:20861159] [PUBMED:19196647] [PUBMED:20043944] [PUBMED:20192774] [PUBMED:18784754] [PUBMED:20559318] [PUBMED:18216767] [PUBMED:17605038] [PUBMED:15269334]
Phosphatidylinositol signaling system [NCBI:83052] [KEGG:hsa04070] [PUBMED:19439500] [PUBMED:19580826]
Phospholipid metabolism [NCBI:1270053] [REACTOME:R-HSA-1483257] [PUBMED:9242906]
Synthesis of PIPs at the Golgi membrane [NCBI:1270075] [REACTOME:R-HSA-1660514] [PUBMED:11279162] [PUBMED:17556371] [PUBMED:10766823] [PUBMED:10559940] [PUBMED:10805725] [PUBMED:14527956] [PUBMED:18950639]
Synthesis of PIPs at the early endosome membrane [NCBI:1270079] [REACTOME:R-HSA-1660516] [PUBMED:18950639] [PUBMED:11733541] [PUBMED:18524850] [PUBMED:17556371] [PUBMED:17651088] [PUBMED:10805725]
Synthesis of PIPs at the late endosome membrane [NCBI:1270082] [REACTOME:R-HSA-1660517] [PUBMED:18524850] [PUBMED:17556371] [PUBMED:17651088] [PUBMED:10805725] [PUBMED:11733541] [PUBMED:18950639]
Synthesis of PIPs at the plasma membrane [NCBI:1270077] [REACTOME:R-HSA-1660499] [PUBMED:16399794] [PUBMED:12646134] [PUBMED:10224048] [PUBMED:9113989] [PUBMED:9211928] [PUBMED:12536145] [PUBMED:22647598] [PUBMED:11733541] [PUBMED:9660759] [PUBMED:19896968]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]
superpathway of inositol phosphate compounds [NCBI:547492] [BIOCYC:HUMAN_PWY-6371]
trans-Golgi Network Vesicle Budding [NCBI:1269880] [REACTOME:R-HSA-199992] [PUBMED:11252894]