full name
potassium voltage-gated channel subfamily J member 11

synonyms
BIR, HHF2, IKATP, KIR6.2, PHHI, TNDM3, KCNJ11, ENSG00000187486

HGNC
HGNC:6257

Entrez Gene
Gene:3767

ENSEMBL
ENSG00000187486

location
chr: 11
start: 17406795
stop: 17410878
strand: -

OMIM
OMIM:600937: KCNJ11 (Autosomal dominant inheritance)
OMIM:610582: Diabetes mellitus, transient neonatal, 3
OMIM:606176: Diabetes, permanent neonatal, with or without neurologic features
OMIM:601820: Hyperinsulinemic hypoglycemia, familial, 2
OMIM:616329: Maturity-onset diabetes of the young, type 13
OMIM:125853: {Diabetes mellitus, type 2, susceptibility to}

transcripts
NM_001166290.1
NM_000525.3

pathways
ABC transporter disorders [NCBI:1268933] [REACTOME:R-HSA-5619084] [PUBMED:21740521] [PUBMED:16399363] [PUBMED:23415156] [PUBMED:21389634] [PUBMED:21488864] [PUBMED:21554546]
ABC-family proteins mediated transport [NCBI:1269904] [REACTOME:R-HSA-382556] [PUBMED:11435397] [PUBMED:12045106] [PUBMED:19234479]
ATP sensitive Potassium channels [NCBI:1268828] [REACTOME:R-HSA-1296025] [PUBMED:18258787] [PUBMED:19787700]
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:19808464] [PUBMED:26140724] [PUBMED:21357845]
Defective ABCC8 can cause hypoglycemias and hyperglycemias [NCBI:1339134] [REACTOME:R-HSA-5683177] [PUBMED:25317244] [PUBMED:25077087] [PUBMED:20500788] [PUBMED:20922570] [PUBMED:18767144]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Disorders of transmembrane transporters [NCBI:1268932] [REACTOME:R-HSA-5619115] [PUBMED:16399363]
FOXA2 and FOXA3 transcription factor networks [NCBI:137911] [Pathway Interaction Database:hnf3bpathway] [PUBMED:14500912] [PUBMED:9632808] [PUBMED:8668179] [PUBMED:2786140] [PUBMED:10748140] [PUBMED:8662915] [PUBMED:12865419] [PUBMED:12145169] [PUBMED:15314688] [PUBMED:12911579] [PUBMED:15123725] [PUBMED:16098831] [PUBMED:10455192] [PUBMED:15616563] [PUBMED:7524494] [PUBMED:7565696] [PUBMED:15959514] [PUBMED:11278466] [PUBMED:9369482] [PUBMED:8813720]
Insulin secretion [NCBI:777534] [KEGG:hsa04911] [PUBMED:9715374] [PUBMED:10605628] [PUBMED:9914469] [PUBMED:17306374] [PUBMED:20055708] [PUBMED:15655710] [PUBMED:19817784] [PUBMED:19074620] [PUBMED:14693691] [PUBMED:17084085] [PUBMED:20551594] [PUBMED:19036624] [PUBMED:22970724] [PUBMED:20225132] [PUBMED:19817800] [PUBMED:22974438] [PUBMED:21934040] [PUBMED:15271645] [PUBMED:19660440] [PUBMED:11522660]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Inwardly rectifying K+ channels [NCBI:1268824] [REACTOME:R-HSA-1296065] [PUBMED:20086079] [PUBMED:18087715] [PUBMED:18691387]
Ion homeostasis [NCBI:1339121] [REACTOME:R-HSA-5578775] [PUBMED:26140724] [PUBMED:17017901]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Potassium Channels [NCBI:1268821] [REACTOME:R-HSA-1296071] [PUBMED:20813163] [PUBMED:19584315] [PUBMED:1822292] [PUBMED:18446619] [PUBMED:18413784] [PUBMED:20213494] [PUBMED:20086079]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:11078440] [PUBMED:16321791] [PUBMED:11815463] [PUBMED:16556766]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
Type II diabetes mellitus [NCBI:83094] [KEGG:hsa04930] [PUBMED:12480546] [PUBMED:15759102] [PUBMED:9011569] [PUBMED:11078440] [PUBMED:11390407] [PUBMED:15258147] [PUBMED:15823385] [PUBMED:11272200] [PUBMED:11325516] [PUBMED:15733744] [PUBMED:9974390] [PUBMED:7491105] [PUBMED:15585596]