full name
CD59 molecule (CD59 blood group)

synonyms
16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, CD59, ENSG00000085063

HGNC
HGNC:1689

Entrez Gene
Gene:966

ENSEMBL
ENSG00000085063

location
chr: 11
start: 33724556
stop: 33758025
strand: -

OMIM
OMIM:107271: CD59 (Autosomal recessive inheritance)
OMIM:612300: Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy

transcripts
NM_000611.5
NM_203331.2
NM_203329.2
NM_203330.2
NM_001127227.1
NM_001127226.1
NM_001127225.1
NM_001127223.1

pathways
Arf6 trafficking events [NCBI:137954] [Pathway Interaction Database:arf6_traffickingpathway] [PUBMED:10748097] [PUBMED:15590645] [PUBMED:15980073] [PUBMED:19644450] [PUBMED:16461286] [PUBMED:14675422] [PUBMED:16139226] [PUBMED:12589044] [PUBMED:15802264] [PUBMED:14585928] [PUBMED:17664335] [PUBMED:17719203] [PUBMED:12960436] [PUBMED:12447393] [PUBMED:11535619] [PUBMED:12657640] [PUBMED:16280360] [PUBMED:9314528] [PUBMED:19211056] [PUBMED:11533043] [PUBMED:12847086] [PUBMED:15146059] [PUBMED:9685333] [PUBMED:12925709] [PUBMED:15231847] [PUBMED:12810696] [PUBMED:14662749] [PUBMED:16030257] [PUBMED:12379803] [PUBMED:15775968] [PUBMED:11532961] [PUBMED:8769418]
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:16807922] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
COPI-mediated anterograde transport [NCBI:1339109] [REACTOME:R-HSA-6807878] [PUBMED:9323141] [PUBMED:15632110] [PUBMED:10825291] [PUBMED:9288971] [PUBMED:23378591] [PUBMED:8334707] [PUBMED:22013193] [PUBMED:23732476]
COPII (Coat Protein 2) Mediated Vesicle Transport [NCBI:1268727] [REACTOME:R-HSA-204005] [PUBMED:17316621] [PUBMED:11252894]
Cargo concentration in the ER [NCBI:1309087] [REACTOME:R-HSA-5694530] [PUBMED:18843296] [PUBMED:25619253] [PUBMED:22013193] [PUBMED:12941277] [PUBMED:12426382] [PUBMED:20533886] [PUBMED:23378591] [PUBMED:12819131] [PUBMED:21878990] [PUBMED:12941276]
Complement and coagulation cascades [NCBI:83073] [KEGG:hsa04610] [PUBMED:23564577] [PUBMED:25309880] [PUBMED:26082779] [PUBMED:23110467] [PUBMED:20027185] [PUBMED:25568220] [PUBMED:26324800] [PUBMED:25705421] [PUBMED:21811895] [PUBMED:23911436] [PUBMED:23564578] [PUBMED:24924409] [PUBMED:26489954] [PUBMED:17635716]
Complement cascade [NCBI:1269241] [REACTOME:R-HSA-166658] [PUBMED:3052276] [PUBMED:11044372] [PUBMED:11213801] [PUBMED:15476920] [PUBMED:14698228]
ER to Golgi Anterograde Transport [NCBI:1268726] [REACTOME:R-HSA-199977] [PUBMED:11252894]
Hematopoietic cell lineage [NCBI:83078] [KEGG:hsa04640] [PUBMED:15629410] [PUBMED:15738953] [PUBMED:11905810] [PUBMED:15156179] [PUBMED:12415312] [PUBMED:14985712] [PUBMED:9927518] [PUBMED:15771582] [PUBMED:14670296] [PUBMED:12360214]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Regulation of Complement cascade [NCBI:1269250] [REACTOME:R-HSA-977606] [PUBMED:19730437] [PUBMED:20720586] [PUBMED:15476920]
Transport to the Golgi and subsequent modification [NCBI:1268725] [REACTOME:R-HSA-948021] [PUBMED:12717434] [PUBMED:10412983] [PUBMED:3594573]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]