full name
pyruvate dehydrogenase complex component X

synonyms
DLDBP, E3BP, OPDX, PDX1, proX, PDHX, ENSG00000110435

HGNC
HGNC:21350

Entrez Gene
Gene:8050

ENSEMBL
ENSG00000110435

location
chr: 11
start: 34937677
stop: 35017675
strand: +

OMIM
OMIM:608769: PDHX (Autosomal recessive inheritance)
OMIM:245349: Lacticacidemia due to PDX1 deficiency

transcripts
NM_003477.2
NM_001166158.1
NM_001135024.1

pathways
Glyoxylate metabolism and glycine degradation [NCBI:1270180] [REACTOME:R-HSA-389661] [PUBMED:15956068]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Pyruvate metabolism [NCBI:82998] [KEGG:hsa00620] [NCBI:1270123] [REACTOME:R-HSA-70268] [PUBMED:2188967] [PUBMED:7273846]
Pyruvate metabolism and Citric Acid (TCA) cycle [NCBI:1270122] [REACTOME:R-HSA-71406]
Regulation of pyruvate dehydrogenase (PDH) complex [NCBI:1270124] [REACTOME:R-HSA-204174] [PUBMED:12676647]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Retinoic Acid [NCBI:1269630] [REACTOME:R-HSA-5362517] [PUBMED:21621639] [PUBMED:21718801] [PUBMED:21529158] [PUBMED:24393720]
The citric acid (TCA) cycle and respiratory electron transport [NCBI:1270121] [REACTOME:R-HSA-1428517]