full name
ubiquitin conjugating enzyme E2 L6

synonyms
RIG-B, UBCH8, UBE2L6, ENSG00000156587

HGNC
HGNC:12490

Entrez Gene
Gene:9246

ENSEMBL
ENSG00000156587

location
chr: 11
start: 57319128
stop: 57335803
strand: -

transcripts
NM_198183.2
NM_004223.4

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Amyloid fiber formation [NCBI:1269169] [REACTOME:R-HSA-977225] [PUBMED:16302959]
Antigen processing: Ubiquitination & Proteasome degradation [NCBI:1269193] [REACTOME:R-HSA-983168] [PUBMED:12648452] [PUBMED:11917093] [PUBMED:19489725] [PUBMED:14734113] [PUBMED:20351195] [PUBMED:17145306]
Antiviral mechanism by IFN-stimulated genes [NCBI:1269316] [REACTOME:R-HSA-1169410]
Class I MHC mediated antigen processing & presentation [NCBI:1269192] [REACTOME:R-HSA-983169] [PUBMED:8717519] [PUBMED:17145306] [PUBMED:18926908] [PUBMED:17055423] [PUBMED:12495737] [PUBMED:18641646] [PUBMED:18243674]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
DNA Damage Bypass [NCBI:1270367] [REACTOME:R-HSA-73893] [PUBMED:21605556] [PUBMED:10925197] [PUBMED:11595180] [PUBMED:12800216] [PUBMED:19225445] [PUBMED:25038291]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
ISG15 antiviral mechanism [NCBI:1269317] [REACTOME:R-HSA-1169408] [PUBMED:20153823] [PUBMED:12582176] [PUBMED:16009940] [PUBMED:20946978] [PUBMED:15970528]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Interferon Signaling [NCBI:1269311] [REACTOME:R-HSA-913531] [PUBMED:18929502] [PUBMED:15607020] [PUBMED:15864272] [PUBMED:14525967] [PUBMED:19059436]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Negative regulators of RIG-I/MDA5 signaling [NCBI:1269264] [REACTOME:R-HSA-936440] [PUBMED:18703349] [PUBMED:18549796]
Parkinson's disease [NCBI:83098] [KEGG:hsa05012] [PUBMED:15767499] [PUBMED:12461550] [PUBMED:21811441] [PUBMED:17911161] [PUBMED:15525720] [PUBMED:16022590] [PUBMED:12971891] [PUBMED:15681812] [PUBMED:16495942] [PUBMED:11331916] [PUBMED:18426756] [PUBMED:16278972] [PUBMED:18680555] [PUBMED:12938733] [PUBMED:15770999] [PUBMED:12728264] [PUBMED:15054086] [PUBMED:20236221] [PUBMED:22927178]
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways [NCBI:1269259] [REACTOME:R-HSA-168928] [PUBMED:17395582] [PUBMED:17942531] [PUBMED:18701081] [PUBMED:17683970] [PUBMED:18989317] [PUBMED:16214811]
Termination of translesion DNA synthesis [NCBI:1270374] [REACTOME:R-HSA-5656169] [PUBMED:24768535] [PUBMED:23000965]
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template [NCBI:1270369] [REACTOME:R-HSA-110313] [PUBMED:10583946] [PUBMED:10856253] [PUBMED:24716551]
Ubiquitin mediated proteolysis [NCBI:83056] [KEGG:hsa04120] [PUBMED:16405856] [PUBMED:12944364] [PUBMED:16922408] [PUBMED:17588513] [PUBMED:16922367] [PUBMED:16922370] [PUBMED:16816840]
protein ubiquitylation [NCBI:1208955] [BIOCYC:HUMAN_PWY-7511]