full name
gastric intrinsic factor

synonyms
IF, IFMH, INF, TCN3, GIF, ENSG00000134812

HGNC
HGNC:4268

Entrez Gene
Gene:2694

ENSEMBL
ENSG00000134812

location
chr: 11
start: 59596746
stop: 59612974
strand: -

OMIM
OMIM:609342: GIF (Autosomal recessive inheritance)
OMIM:261000: Intrinsic factor deficiency

transcripts
NM_005142.2

pathways
Cobalamin (Cbl, vitamin B12) transport and metabolism [NCBI:1270152] [REACTOME:R-HSA-196741] [PUBMED:21312325] [PUBMED:10448521] [PUBMED:20185591] [PUBMED:19832808]
Defective AMN causes hereditary megaloblastic anemia 1 [NCBI:1268961] [REACTOME:R-HSA-3359462] [PUBMED:13852753]
Defective CUBN causes hereditary megaloblastic anemia 1 [NCBI:1268962] [REACTOME:R-HSA-3359463] [PUBMED:13828999]
Defective GIF causes intrinsic factor deficiency [NCBI:1268965] [REACTOME:R-HSA-3359457] [PUBMED:15738392]
Defects in cobalamin (B12) metabolism [NCBI:1268960] [REACTOME:R-HSA-3296469] [PUBMED:21312325] [PUBMED:16846473] [PUBMED:9587028] [PUBMED:21114891] [PUBMED:22547309]
Defects in vitamin and cofactor metabolism [NCBI:1268959] [REACTOME:R-HSA-3296482]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of metabolism [NCBI:1268939] [REACTOME:R-HSA-5668914]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of vitamins and cofactors [NCBI:1270144] [REACTOME:R-HSA-196854]
Metabolism of water-soluble vitamins and cofactors [NCBI:1270145] [REACTOME:R-HSA-196849]
Vitamin digestion and absorption [NCBI:199556] [KEGG:hsa04977] [PUBMED:19173758] [PUBMED:16206251] [PUBMED:14977409] [PUBMED:14642860] [PUBMED:16688755] [PUBMED:19056639] [PUBMED:18841274] [PUBMED:20185591] [PUBMED:16462170] [PUBMED:20724488] [PUBMED:11340090] [PUBMED:11984580] [PUBMED:20166147]