full name
phosphofurin acidic cluster sorting protein 1

synonyms
MRD17, PACS1, ENSG00000175115

HGNC
HGNC:30032

Entrez Gene
Gene:55690

ENSEMBL
ENSG00000175115

location
chr: 11
start: 65837747
stop: 66012218
strand: +

OMIM
OMIM:607492: PACS1
OMIM:615009: Schuurs-Hoeijmakers syndrome

transcripts
NM_018026.3

pathways
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
Host Interactions of HIV factors [NCBI:1269091] [REACTOME:R-HSA-162909]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Nef mediated downregulation of MHC class I complex cell surface expression [NCBI:1269104] [REACTOME:R-HSA-164940] [PUBMED:8612235] [PUBMED:12414957] [PUBMED:12526811] [PUBMED:9586638] [PUBMED:11593029]
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters [NCBI:1269102] [REACTOME:R-HSA-164938] [PUBMED:9811606] [PUBMED:11208076] [PUBMED:9564030] [PUBMED:9586638] [PUBMED:12486136] [PUBMED:9811611] [PUBMED:9384576] [PUBMED:9736718]
The role of Nef in HIV-1 replication and disease pathogenesis [NCBI:1269100] [REACTOME:R-HSA-164952] [PUBMED:16354571]