full name
glutathione S-transferase pi 1

synonyms
DFN7, FAEES3, GST3, GSTP, PI, GSTP1, ENSG00000084207

HGNC
HGNC:4638

Entrez Gene
Gene:2950

ENSEMBL
ENSG00000084207

location
chr: 11
start: 67351066
stop: 67354125
strand: +

transcripts
NM_000852.3

pathways
4-hydroxy-2-nonenal detoxification [NCBI:703096] [BIOCYC:HUMAN_PWY-7112]
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Chemical carcinogenesis [NCBI:673221] [KEGG:hsa05204] [PUBMED:21473878] [PUBMED:15489140] [PUBMED:21255676] [PUBMED:11376689] [PUBMED:15298956] [PUBMED:17445838] [PUBMED:22705365] [PUBMED:9152590] [PUBMED:8759017] [PUBMED:20570348] [PUBMED:11275476] [PUBMED:9202760] [PUBMED:21163908] [PUBMED:10753215] [PUBMED:10913381] [PUBMED:21217854] [PUBMED:15582261] [PUBMED:16959879] [PUBMED:11092599] [PUBMED:20159989] [PUBMED:21234336] [PUBMED:17459420] [PUBMED:9275165] [PUBMED:17292678] [PUBMED:11978484] [PUBMED:11222868] [PUBMED:15660110] [PUBMED:8702479] [PUBMED:9356303] [PUBMED:20232918] [PUBMED:12435844] [PUBMED:19657920] [PUBMED:8951235] [PUBMED:15532073] [PUBMED:16084004] [PUBMED:18066431] [PUBMED:14570033] [PUBMED:16421178] [PUBMED:21154658] [PUBMED:12928348] [PUBMED:19531241] [PUBMED:20669524] [PUBMED:11467078] [PUBMED:22178655] [PUBMED:21456541]
Detoxification of Reactive Oxygen Species [NCBI:1270420] [REACTOME:R-HSA-3299685] [PUBMED:23469953] [PUBMED:23268465] [PUBMED:20064600] [PUBMED:22286106] [PUBMED:21473702] [PUBMED:22196163] [PUBMED:21375475] [PUBMED:19061483] [PUBMED:21453242]
Drug metabolism - cytochrome P450 [NCBI:83032] [KEGG:hsa00982] [PUBMED:16550168] [PUBMED:10575324] [PUBMED:11226815] [PUBMED:16393888] [PUBMED:12399158] [PUBMED:11504799] [PUBMED:16038189] [PUBMED:10901707] [PUBMED:18043895] [PUBMED:18463198] [PUBMED:9698084] [PUBMED:12386121] [PUBMED:10859160]
Fluid shear stress and atherosclerosis [NCBI:1474302] [KEGG:hsa05418] [PUBMED:23429585] [PUBMED:21050140] [PUBMED:17599600] [PUBMED:24190880] [PUBMED:22003002] [PUBMED:24876354] [PUBMED:24947523] [PUBMED:23899566] [PUBMED:26597822] [PUBMED:20353494] [PUBMED:22076424] [PUBMED:20538799] [PUBMED:25165867] [PUBMED:20032497] [PUBMED:23084990] [PUBMED:26822720] [PUBMED:24573382] [PUBMED:23555159] [PUBMED:26212910] [PUBMED:21457103] [PUBMED:19151844] [PUBMED:15388638] [PUBMED:16765337] [PUBMED:27027326] [PUBMED:25638487] [PUBMED:21733876]
Glutathione conjugation [NCBI:1270213] [REACTOME:R-HSA-156590]
Glutathione metabolism [NCBI:82973] [KEGG:hsa00480] [PUBMED:18395526] [PUBMED:15537651] [PUBMED:12466271] [PUBMED:9677355] [PUBMED:11157967] [PUBMED:12675513] [PUBMED:18482986] [PUBMED:8892297] [PUBMED:12751784] [PUBMED:12750367] [PUBMED:14982633] [PUBMED:11150302] [PUBMED:12121990] [PUBMED:15610825] [PUBMED:17922848] [PUBMED:12049631] [PUBMED:12949079] [PUBMED:7813456] [PUBMED:9851611] [PUBMED:6798961] [PUBMED:10713147] [PUBMED:12967709] [PUBMED:14583094] [PUBMED:12446213]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of xenobiotics by cytochrome P450 [NCBI:83031] [KEGG:hsa00980] [PUBMED:9107551] [PUBMED:10570027] [PUBMED:4395686] [PUBMED:10490505] [PUBMED:15987776] [PUBMED:15298956] [PUBMED:15319346] [PUBMED:12487150] [PUBMED:10725110]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Phase II conjugation [NCBI:1270207] [REACTOME:R-HSA-156580] [PUBMED:11805192]
Platinum drug resistance [NCBI:1404797] [KEGG:hsa01524] [PUBMED:24074238] [PUBMED:26867799] [PUBMED:14609433] [PUBMED:26184483] [PUBMED:24874729] [PUBMED:15607932] [PUBMED:25546083] [PUBMED:25058905] [PUBMED:19190080] [PUBMED:14576837] [PUBMED:20811617] [PUBMED:21892204] [PUBMED:20647037] [PUBMED:17336087] [PUBMED:26886018] [PUBMED:23442359] [PUBMED:17625587]
Prostate cancer [NCBI:83111] [KEGG:hsa05215] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11527574] [PUBMED:11750244] [PUBMED:16551847] [PUBMED:10835690] [PUBMED:8069858] [PUBMED:15724144] [PUBMED:10453277] [PUBMED:15082523] [PUBMED:9422516]
glutathione-mediated detoxification [NCBI:142435] [BIOCYC:HUMAN_PWY-4061] [PUBMED:4892500] [PUBMED:4024656] [PUBMED:9755286] [PUBMED:15627473] [PUBMED:5627473] [PUBMED:11876405] [PUBMED:12480900] [PUBMED:9045797]