Logo
full name
fibroblast growth factor 4

synonyms
HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF, FGF4, ENSG00000075388

HGNC
HGNC:3682

Entrez Gene
Gene:2249

ENSEMBL
ENSG00000075388

location
chr: 11
start: 69587797
stop: 69590171
strand: -

transcripts
NM_002007.2

pathways
ARMS-mediated activation [NCBI:1269471] [REACTOME:R-HSA-170984] [PUBMED:9069267]
Activated point mutants of FGFR2 [NCBI:1268871] [REACTOME:R-HSA-2033519] [PUBMED:17525745] [PUBMED:8841188] [PUBMED:9539778] [PUBMED:7719344] [PUBMED:9154000] [PUBMED:7874169] [PUBMED:11325814] [PUBMED:11121055] [PUBMED:20106510] [PUBMED:7773297] [PUBMED:15282208] [PUBMED:18552176] [PUBMED:17803937] [PUBMED:17552943] [PUBMED:18757403] [PUBMED:8696350] [PUBMED:9538690]
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Breast cancer [NCBI:1435207] [KEGG:hsa05224] [PUBMED:24649067] [PUBMED:26040571] [PUBMED:11879567] [PUBMED:22722193] [PUBMED:26028978] [PUBMED:25013431] [PUBMED:11737884] [PUBMED:23702927] [PUBMED:21076461] [PUBMED:21898546] [PUBMED:27390604] [PUBMED:24291072] [PUBMED:26968398] [PUBMED:20087430] [PUBMED:23000897] [PUBMED:25544707] [PUBMED:24596345] [PUBMED:23988612] [PUBMED:24111892] [PUBMED:25907219] [PUBMED:15343273] [PUBMED:21965336] [PUBMED:23881035] [PUBMED:23196196] [PUBMED:22178455] [PUBMED:20436504] [PUBMED:19088017] [PUBMED:16113099] [PUBMED:20971825]
Constitutive Signaling by Aberrant PI3K in Cancer [NCBI:1268880] [REACTOME:R-HSA-2219530] [PUBMED:18317450] [PUBMED:19962665] [PUBMED:20009532] [PUBMED:20713702] [PUBMED:21478295] [PUBMED:16339315] [PUBMED:18079394] [PUBMED:17626883]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
Downstream signaling events of B Cell Receptor (BCR) [NCBI:1269185] [REACTOME:R-HSA-1168372] [PUBMED:17052215] [PUBMED:19909372]
Downstream signaling of activated FGFR1 [NCBI:1269392] [REACTOME:R-HSA-5654687] [PUBMED:8752212]
Downstream signaling of activated FGFR2 [NCBI:1269403] [REACTOME:R-HSA-5654696] [PUBMED:8752212]
Downstream signaling of activated FGFR3 [NCBI:1269413] [REACTOME:R-HSA-5654708] [PUBMED:8752212]
Downstream signaling of activated FGFR4 [NCBI:1269422] [REACTOME:R-HSA-5654716] [PUBMED:8752212]
FCERI mediated MAPK activation [NCBI:1269299] [REACTOME:R-HSA-2871796] [PUBMED:19290926] [PUBMED:19909365] [PUBMED:17122878]
FGFR1 ligand binding and activation [NCBI:1269388] [REACTOME:R-HSA-190242] [PUBMED:12791257] [PUBMED:16597617] [PUBMED:12141425] [PUBMED:16045455]
FGFR1 mutant receptor activation [NCBI:1268865] [REACTOME:R-HSA-1839124] [PUBMED:17552943] [PUBMED:21367659] [PUBMED:21711248] [PUBMED:9538690] [PUBMED:20094046] [PUBMED:9154000]
FGFR1c ligand binding and activation [NCBI:1269390] [REACTOME:R-HSA-190373] [PUBMED:16597617]
FGFR2 ligand binding and activation [NCBI:1269400] [REACTOME:R-HSA-190241] [PUBMED:16844695] [PUBMED:16597617] [PUBMED:17133345]
FGFR2 mutant receptor activation [NCBI:1268870] [REACTOME:R-HSA-1839126] [PUBMED:15282208] [PUBMED:17552943] [PUBMED:9266968] [PUBMED:17803937] [PUBMED:9816310] [PUBMED:18757403] [PUBMED:11003564] [PUBMED:20101236] [PUBMED:18337450] [PUBMED:9538690] [PUBMED:17525745] [PUBMED:10626794] [PUBMED:11056689] [PUBMED:18381441] [PUBMED:11325814] [PUBMED:9539778] [PUBMED:19103595] [PUBMED:9154000] [PUBMED:20106510] [PUBMED:17505008] [PUBMED:18552176]
FGFR2c ligand binding and activation [NCBI:1269402] [REACTOME:R-HSA-190375] [PUBMED:16597617]
FGFR3 ligand binding and activation [NCBI:1269410] [REACTOME:R-HSA-190239] [PUBMED:15748888] [PUBMED:16597617] [PUBMED:9045692]
FGFR3 mutant receptor activation [NCBI:1268874] [REACTOME:R-HSA-2033514] [PUBMED:11429702] [PUBMED:9865713] [PUBMED:10568829] [PUBMED:12835230] [PUBMED:9538690] [PUBMED:21711248] [PUBMED:9207791] [PUBMED:9154000]
FGFR3c ligand binding and activation [NCBI:1269412] [REACTOME:R-HSA-190372] [PUBMED:16597617]
FGFR4 ligand binding and activation [NCBI:1269420] [REACTOME:R-HSA-190322] [PUBMED:15467729] [PUBMED:1385111] [PUBMED:16597617] [PUBMED:7518429]
FGFRL1 modulation of FGFR1 signaling [NCBI:1383021] [REACTOME:R-HSA-5658623] [PUBMED:23112089] [PUBMED:21080029]
FRS-mediated FGFR1 signaling [NCBI:1269393] [REACTOME:R-HSA-5654693] [PUBMED:15863030] [PUBMED:18452557] [PUBMED:11447289] [PUBMED:16682955]
FRS-mediated FGFR2 signaling [NCBI:1269404] [REACTOME:R-HSA-5654700] [PUBMED:18452557] [PUBMED:11447289] [PUBMED:16682955] [PUBMED:15863030]
FRS-mediated FGFR3 signaling [NCBI:1269414] [REACTOME:R-HSA-5654706] [PUBMED:15863030] [PUBMED:18452557] [PUBMED:11447289] [PUBMED:16682955]
FRS-mediated FGFR4 signaling [NCBI:1269423] [REACTOME:R-HSA-5654712] [PUBMED:18452557] [PUBMED:11447289] [PUBMED:16682955] [PUBMED:15863030]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:15099567] [PUBMED:21799019]
Frs2-mediated activation [NCBI:1269470] [REACTOME:R-HSA-170968] [PUBMED:9069267]
GAB1 signalosome [NCBI:1269384] [REACTOME:R-HSA-180292] [PUBMED:15550174]
GRB2 events in EGFR signaling [NCBI:1269382] [REACTOME:R-HSA-179812] [PUBMED:11706405] [PUBMED:11498013]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
IGF1R signaling cascade [NCBI:1269618] [REACTOME:R-HSA-2428924] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959]
IRS-mediated signalling [NCBI:1269431] [REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R [NCBI:1269620] [REACTOME:R-HSA-2428928] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:18927274] [PUBMED:21042815] [PUBMED:20098959]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Insulin receptor signalling cascade [NCBI:1269429] [REACTOME:R-HSA-74751] [PUBMED:9677303] [PUBMED:11282018]
Interleukin receptor SHC signaling [NCBI:1269322] [REACTOME:R-HSA-912526] [PUBMED:8294403]
Interleukin-2 signaling [NCBI:1269321] [REACTOME:R-HSA-451927] [PUBMED:17936914] [PUBMED:18817510] [PUBMED:19543225] [PUBMED:18062768]
Interleukin-3, 5 and GM-CSF signaling [NCBI:1269323] [REACTOME:R-HSA-512988] [PUBMED:10450743] [PUBMED:9766809]
MAPK family signaling cascades [NCBI:1269501] [REACTOME:R-HSA-5683057] [PUBMED:21167873] [PUBMED:17161475] [PUBMED:22535895] [PUBMED:21372320]
MAPK signaling pathway [NCBI:83048] [KEGG:hsa04010] [PUBMED:11749383] [PUBMED:12566928] [PUBMED:12849693] [PUBMED:12676795] [PUBMED:12947395] [PUBMED:14597384] [PUBMED:11369511] [PUBMED:12191611] [PUBMED:12390245]
MAPK1/MAPK3 signaling [NCBI:1269502] [REACTOME:R-HSA-5684996] [PUBMED:25378393] [PUBMED:18199641] [PUBMED:17496909] [PUBMED:21779496] [PUBMED:15520807] [PUBMED:16393692] [PUBMED:19520853] [PUBMED:17496910] [PUBMED:22569528]
Melanoma [NCBI:83114] [KEGG:hsa05218] [PUBMED:16822996] [PUBMED:14695152] [PUBMED:11224709] [PUBMED:10843728] [PUBMED:12894244] [PUBMED:16899407] [PUBMED:16001072] [PUBMED:15721476] [PUBMED:15557758] [PUBMED:15009714] [PUBMED:16001050] [PUBMED:15841168] [PUBMED:16750612]
NCAM signaling for neurite out-growth [NCBI:1270312] [REACTOME:R-HSA-375165] [PUBMED:18760361] [PUBMED:12587671] [PUBMED:15662836] [PUBMED:17975827] [PUBMED:15153429] [PUBMED:12700044]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Negative regulation of FGFR1 signaling [NCBI:1269397] [REACTOME:R-HSA-5654726] [PUBMED:18452557] [PUBMED:11997436] [PUBMED:20940169] [PUBMED:12815057]
Negative regulation of FGFR2 signaling [NCBI:1269408] [REACTOME:R-HSA-5654727] [PUBMED:12815057] [PUBMED:18452557] [PUBMED:11997436] [PUBMED:20940169]
Negative regulation of FGFR3 signaling [NCBI:1269418] [REACTOME:R-HSA-5654732] [PUBMED:12815057] [PUBMED:18452557] [PUBMED:11997436] [PUBMED:20940169]
Negative regulation of FGFR4 signaling [NCBI:1269427] [REACTOME:R-HSA-5654733] [PUBMED:12815057] [PUBMED:18452557] [PUBMED:11997436] [PUBMED:20940169]
Negative regulation of the PI3K/AKT network [NCBI:1269191] [REACTOME:R-HSA-199418]
PI-3K cascade:FGFR1 [NCBI:1269396] [REACTOME:R-HSA-5654689] [PUBMED:15863030] [PUBMED:11057895] [PUBMED:12089343] [PUBMED:12558974] [PUBMED:10918587]
PI-3K cascade:FGFR2 [NCBI:1269407] [REACTOME:R-HSA-5654695] [PUBMED:10918587] [PUBMED:15863030] [PUBMED:11057895] [PUBMED:12558974] [PUBMED:12089343]
PI-3K cascade:FGFR3 [NCBI:1269417] [REACTOME:R-HSA-5654710] [PUBMED:10918587] [PUBMED:15863030] [PUBMED:11057895] [PUBMED:12089343] [PUBMED:12558974]
PI-3K cascade:FGFR4 [NCBI:1269426] [REACTOME:R-HSA-5654720] [PUBMED:10918587] [PUBMED:15863030] [PUBMED:11057895] [PUBMED:12558974] [PUBMED:12089343]
PI3K Cascade [NCBI:1269432] [REACTOME:R-HSA-109704]
PI3K-Akt signaling pathway [NCBI:692234] [KEGG:hsa04151] [PUBMED:12048182] [PUBMED:11357143] [PUBMED:21440011] [PUBMED:15209374] [PUBMED:12669022] [PUBMED:18842113] [PUBMED:16847462] [PUBMED:12660731] [PUBMED:17360849] [PUBMED:9838078] [PUBMED:15505410] [PUBMED:16248975] [PUBMED:12531180] [PUBMED:21779440] [PUBMED:16187290] [PUBMED:15784165] [PUBMED:21620960]
PI3K/AKT Signaling in Cancer [NCBI:1268879] [REACTOME:R-HSA-2219528] [PUBMED:20713702] [PUBMED:10555148] [PUBMED:19644473] [PUBMED:17611497] [PUBMED:21478295] [PUBMED:17626883] [PUBMED:16339315] [PUBMED:18317450] [PUBMED:18079394] [PUBMED:9467011] [PUBMED:17604717] [PUBMED:9326929] [PUBMED:18954143] [PUBMED:20009532] [PUBMED:19962665] [PUBMED:21430697] [PUBMED:19487573] [PUBMED:10866302]
PI3K/AKT activation [NCBI:1269473] [REACTOME:R-HSA-198203] [PUBMED:10579926] [PUBMED:12123609]
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling [NCBI:1383020] [REACTOME:R-HSA-6811558] [PUBMED:12422219] [PUBMED:16979564] [PUBMED:19805105] [PUBMED:17200115] [PUBMED:21827948] [PUBMED:19576174] [PUBMED:18753295] [PUBMED:19896968] [PUBMED:16456541] [PUBMED:25495341] [PUBMED:15464023] [PUBMED:23758345] [PUBMED:9367159] [PUBMED:9211928] [PUBMED:17245604]
PIP3 activates AKT signaling [NCBI:1269188] [REACTOME:R-HSA-1257604]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Phospholipase C-mediated cascade: FGFR1 [NCBI:1269394] [REACTOME:R-HSA-5654219] [PUBMED:10579907] [PUBMED:1656221] [PUBMED:15863030]
Phospholipase C-mediated cascade; FGFR2 [NCBI:1269405] [REACTOME:R-HSA-5654221] [PUBMED:10579907] [PUBMED:1656221] [PUBMED:15863030]
Phospholipase C-mediated cascade; FGFR3 [NCBI:1269415] [REACTOME:R-HSA-5654227] [PUBMED:15863030] [PUBMED:10579907] [PUBMED:1656221]
Phospholipase C-mediated cascade; FGFR4 [NCBI:1269424] [REACTOME:R-HSA-5654228] [PUBMED:10579907] [PUBMED:1656221] [PUBMED:15863030]
Prolonged ERK activation events [NCBI:1269469] [REACTOME:R-HSA-169893] [PUBMED:12765839] [PUBMED:9069267]
RAF/MAP kinase cascade [NCBI:1269285] [REACTOME:R-HSA-5673001] [PUBMED:21167873] [PUBMED:24937142] [PUBMED:20674547] [PUBMED:17496910] [PUBMED:22177953] [PUBMED:17496919] [PUBMED:22569528] [PUBMED:22535895] [PUBMED:12068308] [PUBMED:17496923] [PUBMED:19091303] [PUBMED:21372320] [PUBMED:21388974] [PUBMED:15520807]
RET signaling [NCBI:1427866] [REACTOME:R-HSA-8853659] [PUBMED:15013219] [PUBMED:17036197]
Rap1 signaling pathway [NCBI:868086] [KEGG:hsa04015] [PUBMED:17624944] [PUBMED:12351703] [PUBMED:10579920] [PUBMED:19159611] [PUBMED:18363565] [PUBMED:12765839] [PUBMED:12508104] [PUBMED:11331911] [PUBMED:17182900] [PUBMED:15803158] [PUBMED:19615876] [PUBMED:21402149] [PUBMED:17624948] [PUBMED:17383543] [PUBMED:14607972] [PUBMED:15780587] [PUBMED:19710505]
Ras signaling pathway [NCBI:868085] [KEGG:hsa04014] [PUBMED:23506953] [PUBMED:18437264] [PUBMED:15062121] [PUBMED:22189424] [PUBMED:22233291] [PUBMED:12778136] [PUBMED:11313946] [PUBMED:17428555] [PUBMED:19091743] [PUBMED:18568040] [PUBMED:20420946] [PUBMED:12217381] [PUBMED:14663478] [PUBMED:21686117] [PUBMED:12642680] [PUBMED:21196257] [PUBMED:16869784] [PUBMED:21111786] [PUBMED:16966426] [PUBMED:10712923] [PUBMED:22020205] [PUBMED:17384584] [PUBMED:15572660] [PUBMED:18413813]
Regulation of Wnt-mediated beta catenin signaling and target gene transcription [NCBI:169352] [Pathway Interaction Database:wnt_beta_catenin_pathway] [PUBMED:19901072] [PUBMED:19699733] [PUBMED:15142975] [PUBMED:16565090] [PUBMED:17372190] [PUBMED:17310985] [PUBMED:11751639] [PUBMED:16301527] [PUBMED:10921920] [PUBMED:8622675] [PUBMED:19571879] [PUBMED:11445543] [PUBMED:19066453] [PUBMED:15768032] [PUBMED:10704849] [PUBMED:19940019] [PUBMED:15378020] [PUBMED:10318916] [PUBMED:10617567] [PUBMED:19435523] [PUBMED:18511409] [PUBMED:18006687] [PUBMED:14638683] [PUBMED:15782138] [PUBMED:15143193] [PUBMED:9671490] [PUBMED:11263497] [PUBMED:18193033] [PUBMED:9751710] [PUBMED:11532957] [PUBMED:10898789] [PUBMED:11266540] [PUBMED:17090534] [PUBMED:15492215] [PUBMED:16309666] [PUBMED:12502739] [PUBMED:10980707] [PUBMED:17945188] [PUBMED:11572874] [PUBMED:11809808] [PUBMED:17113388] [PUBMED:20128690] [PUBMED:17709391] [PUBMED:11500377] [PUBMED:12464179] [PUBMED:18347071] [PUBMED:18347094] [PUBMED:15592430] [PUBMED:10958684] [PUBMED:12408825] [PUBMED:15525529] [PUBMED:16581771] [PUBMED:12052822] [PUBMED:15668231] [PUBMED:16014379] [PUBMED:17923689] [PUBMED:15592505] [PUBMED:10984057] [PUBMED:20044351] [PUBMED:11940574] [PUBMED:10747853] [PUBMED:12606575] [PUBMED:15728254] [PUBMED:11080158] [PUBMED:12446687] [PUBMED:20128911] [PUBMED:19816403] [PUBMED:18573912] [PUBMED:17397822] [PUBMED:10489374] [PUBMED:17052462] [PUBMED:20371816] [PUBMED:18347063] [PUBMED:11035805] [PUBMED:11792709] [PUBMED:16899215] [PUBMED:10882123] [PUBMED:12200448] [PUBMED:15060161] [PUBMED:12711682] [PUBMED:12582159] [PUBMED:12646922] [PUBMED:19460168] [PUBMED:16778892] [PUBMED:17306568] [PUBMED:12712206] [PUBMED:19711354] [PUBMED:17893322] [PUBMED:10934025] [PUBMED:19503085] [PUBMED:19433865]
Regulation of actin cytoskeleton [NCBI:83089] [KEGG:hsa04810] [PUBMED:11152757] [PUBMED:11082272] [PUBMED:10574699] [PUBMED:11082269] [PUBMED:14657486] [PUBMED:14744429] [PUBMED:12700767]
Role of LAT2/NTAL/LAB on calcium mobilization [NCBI:1269302] [REACTOME:R-HSA-2730905] [PUBMED:17993265] [PUBMED:20643813] [PUBMED:17420272]
SHC-mediated cascade:FGFR1 [NCBI:1269395] [REACTOME:R-HSA-5654688] [PUBMED:9045692] [PUBMED:18840094] [PUBMED:15863030] [PUBMED:8264585] [PUBMED:9480847]
SHC-mediated cascade:FGFR2 [NCBI:1269406] [REACTOME:R-HSA-5654699] [PUBMED:8264585] [PUBMED:9480847] [PUBMED:9045692] [PUBMED:18840094] [PUBMED:15863030]
SHC-mediated cascade:FGFR3 [NCBI:1269416] [REACTOME:R-HSA-5654704] [PUBMED:9045692] [PUBMED:18840094] [PUBMED:15863030] [PUBMED:8264585] [PUBMED:9480847]
SHC-mediated cascade:FGFR4 [NCBI:1269425] [REACTOME:R-HSA-5654719] [PUBMED:8264585] [PUBMED:9480847] [PUBMED:9045692] [PUBMED:18840094] [PUBMED:15863030]
SHC1 events in EGFR signaling [NCBI:1269383] [REACTOME:R-HSA-180336] [PUBMED:11498013] [PUBMED:8755247]
SOS-mediated signalling [NCBI:1269440] [REACTOME:R-HSA-112412]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by FGFR [NCBI:1269386] [REACTOME:R-HSA-190236] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:20602996] [PUBMED:15863030] [PUBMED:15567848] [PUBMED:7917292] [PUBMED:19247306] [PUBMED:16597617]
Signaling by FGFR in disease [NCBI:1268863] [REACTOME:R-HSA-1226099] [PUBMED:17552943] [PUBMED:10053006] [PUBMED:8640234] [PUBMED:9865713] [PUBMED:21367659] [PUBMED:10471491] [PUBMED:21711248] [PUBMED:9538690] [PUBMED:20094046] [PUBMED:9539778] [PUBMED:12461689] [PUBMED:9438390] [PUBMED:8841188] [PUBMED:11055896] [PUBMED:8599935] [PUBMED:21160078] [PUBMED:9207791] [PUBMED:9154000] [PUBMED:18381441] [PUBMED:20179196] [PUBMED:8755573] [PUBMED:20226962] [PUBMED:8798788] [PUBMED:19066716] [PUBMED:17505008] [PUBMED:11429702]
Signaling by FGFR1 [NCBI:1269387] [REACTOME:R-HSA-5654736] [PUBMED:16597617] [PUBMED:19247306] [PUBMED:12080084] [PUBMED:15863038] [PUBMED:15567848] [PUBMED:20602996] [PUBMED:7917292] [PUBMED:15863030]
Signaling by FGFR1 in disease [NCBI:1268864] [REACTOME:R-HSA-5655302] [PUBMED:24588013] [PUBMED:20094046] [PUBMED:18056464] [PUBMED:18772890] [PUBMED:14613973] [PUBMED:7874169] [PUBMED:9154000] [PUBMED:20226962] [PUBMED:16140923] [PUBMED:17552943] [PUBMED:21367659] [PUBMED:21711248] [PUBMED:9538690]
Signaling by FGFR2 [NCBI:1269399] [REACTOME:R-HSA-5654738] [PUBMED:19247306] [PUBMED:16597617] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:15863030] [PUBMED:20602996] [PUBMED:15567848] [PUBMED:7917292]
Signaling by FGFR2 in disease [NCBI:1268869] [REACTOME:R-HSA-5655253] [PUBMED:9154000] [PUBMED:17505008] [PUBMED:17552943] [PUBMED:21367659] [PUBMED:21711248] [PUBMED:9538690] [PUBMED:18381441] [PUBMED:19147536]
Signaling by FGFR3 [NCBI:1269409] [REACTOME:R-HSA-5654741] [PUBMED:16597617] [PUBMED:19247306] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:20602996] [PUBMED:15567848] [PUBMED:7917292] [PUBMED:15863030]
Signaling by FGFR3 in disease [NCBI:1268873] [REACTOME:R-HSA-5655332] [PUBMED:19749790] [PUBMED:24850843] [PUBMED:21711248] [PUBMED:23298836] [PUBMED:9538690] [PUBMED:24588013] [PUBMED:9438390] [PUBMED:23558953] [PUBMED:9279753] [PUBMED:8841188] [PUBMED:9207791] [PUBMED:11055896] [PUBMED:9154000] [PUBMED:7670477] [PUBMED:8589699] [PUBMED:11466624] [PUBMED:7647778] [PUBMED:7913883] [PUBMED:19066716] [PUBMED:25246530] [PUBMED:23175443] [PUBMED:8078586] [PUBMED:7773297] [PUBMED:8640234] [PUBMED:15282208] [PUBMED:8845844] [PUBMED:10053006] [PUBMED:7847369] [PUBMED:25535896] [PUBMED:9865713] [PUBMED:10377013] [PUBMED:10471491]
Signaling by FGFR3 point mutants in cancer [NCBI:1383047] [REACTOME:R-HSA-8853338] [PUBMED:7773297] [PUBMED:15282208] [PUBMED:19066716] [PUBMED:10053006] [PUBMED:9865713] [PUBMED:8640234] [PUBMED:8845844] [PUBMED:7847369] [PUBMED:7913883] [PUBMED:7647778] [PUBMED:11466624] [PUBMED:7670477] [PUBMED:8078586] [PUBMED:11055896] [PUBMED:9438390] [PUBMED:8841188] [PUBMED:9279753] [PUBMED:8589699] [PUBMED:9207791] [PUBMED:9154000] [PUBMED:10377013] [PUBMED:10471491] [PUBMED:19749790] [PUBMED:21711248] [PUBMED:9538690]
Signaling by FGFR4 [NCBI:1269419] [REACTOME:R-HSA-5654743] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:15567848] [PUBMED:20602996] [PUBMED:7917292] [PUBMED:15863030] [PUBMED:19247306] [PUBMED:16597617]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Insulin receptor [NCBI:1269428] [REACTOME:R-HSA-74752] [PUBMED:8276779]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Signaling by Leptin [NCBI:1269632] [REACTOME:R-HSA-2586552] [PUBMED:22211890] [PUBMED:23562747] [PUBMED:20600241] [PUBMED:21622208] [PUBMED:23579596] [PUBMED:22458591] [PUBMED:21489811] [PUBMED:19724019] [PUBMED:21331644] [PUBMED:22448029] [PUBMED:21147620] [PUBMED:20198122] [PUBMED:21677426] [PUBMED:20029269] [PUBMED:22249808] [PUBMED:22991412] [PUBMED:21527729] [PUBMED:17937601] [PUBMED:20553370] [PUBMED:21713385] [PUBMED:23565489] [PUBMED:22289780]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signaling by SCF-KIT [NCBI:1269487] [REACTOME:R-HSA-1433557] [PUBMED:17350321] [PUBMED:16483568] [PUBMED:7688988] [PUBMED:19540337] [PUBMED:16475976] [PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) [NCBI:1269617] [REACTOME:R-HSA-2404192] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22044904] [PUBMED:22649417]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
Signaling by activated point mutants of FGFR1 [NCBI:1268868] [REACTOME:R-HSA-1839122] [PUBMED:21711248] [PUBMED:9538690] [PUBMED:20094046] [PUBMED:11055896] [PUBMED:18056464] [PUBMED:18772890] [PUBMED:9154000] [PUBMED:7874169] [PUBMED:7670477] [PUBMED:16140923] [PUBMED:16186508] [PUBMED:7773297] [PUBMED:10053006] [PUBMED:17552943]
Signaling by activated point mutants of FGFR3 [NCBI:1268875] [REACTOME:R-HSA-1839130] [PUBMED:21711248] [PUBMED:8599935] [PUBMED:8754806]
Signaling by the B Cell Receptor (BCR) [NCBI:1269183] [REACTOME:R-HSA-983705] [PUBMED:1702903] [PUBMED:2011584] [PUBMED:1081164] [PUBMED:19065780] [PUBMED:16849466] [PUBMED:1375264] [PUBMED:7538118] [PUBMED:11901194] [PUBMED:8580068] [PUBMED:19249086] [PUBMED:18596693] [PUBMED:10648173] [PUBMED:4589993] [PUBMED:8163536] [PUBMED:1376928] [PUBMED:7688784] [PUBMED:6335036] [PUBMED:17052215] [PUBMED:18818202] [PUBMED:20206686] [PUBMED:7592958] [PUBMED:7524079] [PUBMED:15489917] [PUBMED:15509800] [PUBMED:18187424] [PUBMED:7927516] [PUBMED:803528] [PUBMED:19909372] [PUBMED:20192804] [PUBMED:8306975]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
Signalling to ERKs [NCBI:1269464] [REACTOME:R-HSA-187687] [PUBMED:10508738]
Signalling to RAS [NCBI:1269465] [REACTOME:R-HSA-167044] [PUBMED:11520933]
Signalling to p38 via RIT and RIN [NCBI:1269468] [REACTOME:R-HSA-187706] [PUBMED:10712923]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:17344076] [PUBMED:16633338] [PUBMED:19230644] [PUBMED:13678960]
VEGFR2 mediated cell proliferation [NCBI:1269485] [REACTOME:R-HSA-5218921] [PUBMED:22866201] [PUBMED:22180219] [PUBMED:22762016]