full name
cortactin

synonyms
EMS1, CTTN, ENSG00000085733

HGNC
HGNC:3338

Entrez Gene
Gene:2017

ENSEMBL
ENSG00000085733

location
chr: 11
start: 70244612
stop: 70282690
strand: +

transcripts
NM_005231.3
NM_138565.2
NM_001184740.1

pathways
Bacterial invasion of epithelial cells [NCBI:149807] [KEGG:hsa05100] [PUBMED:17298394] [PUBMED:16406780] [PUBMED:19185531] [PUBMED:19157959] [PUBMED:17719540] [PUBMED:19296488]
Clathrin-mediated endocytosis [NCBI:1427858] [REACTOME:R-HSA-8856828] [PUBMED:16516836] [PUBMED:15339664] [PUBMED:19754444] [PUBMED:8552632] [PUBMED:21779028] [PUBMED:12353027] [PUBMED:23891661] [PUBMED:21613550] [PUBMED:20059951] [PUBMED:21447041] [PUBMED:17620409] [PUBMED:16903783] [PUBMED:21445324] [PUBMED:19696798] [PUBMED:26246598] [PUBMED:25085911] [PUBMED:24186068] [PUBMED:26829388] [PUBMED:27092250] [PUBMED:24581490] [PUBMED:26042225] [PUBMED:23823722] [PUBMED:24789820] [PUBMED:9736607] [PUBMED:23637288] [PUBMED:22233676] [PUBMED:19458185] [PUBMED:26403691] [PUBMED:19296720] [PUBMED:15703209] [PUBMED:20428113] [PUBMED:8953040] [PUBMED:1177317] [PUBMED:9092476] [PUBMED:26872272] [PUBMED:19092055]
E-cadherin signaling in the nascent adherens junction [NCBI:138005] [Pathway Interaction Database:ecadherin_nascentaj_pathway] [PUBMED:16371509] [PUBMED:9694656] [PUBMED:9214391] [PUBMED:17620337] [PUBMED:7969453] [PUBMED:11882288] [PUBMED:19158278] [PUBMED:11716761] [PUBMED:10402472] [PUBMED:15263019] [PUBMED:12427869] [PUBMED:11457821] [PUBMED:6976838] [PUBMED:10037790] [PUBMED:10660044] [PUBMED:15857834] [PUBMED:10202138] [PUBMED:10980705] [PUBMED:15159390] [PUBMED:2349235] [PUBMED:19114658] [PUBMED:14585958] [PUBMED:18632982] [PUBMED:12432063] [PUBMED:17261850] [PUBMED:10383446] [PUBMED:11329369] [PUBMED:14699157] [PUBMED:7954478] [PUBMED:10629228] [PUBMED:8207061] [PUBMED:15556934] [PUBMED:10473551] [PUBMED:12370292] [PUBMED:14610055] [PUBMED:16170364] [PUBMED:12770907] [PUBMED:17553930] [PUBMED:17164293] [PUBMED:2788574] [PUBMED:9512503] [PUBMED:10201395] [PUBMED:15254236] [PUBMED:15024035] [PUBMED:12447393] [PUBMED:11744701] [PUBMED:14668487] [PUBMED:18187454]
FGF signaling pathway [NCBI:137989] [Pathway Interaction Database:fgf_pathway] [PUBMED:12419216] [PUBMED:16775459] [PUBMED:1656221] [PUBMED:16857743] [PUBMED:8707855] [PUBMED:17545628] [PUBMED:17623664] [PUBMED:16893902] [PUBMED:15105428] [PUBMED:16436388] [PUBMED:12370824] [PUBMED:9707175] [PUBMED:1380001] [PUBMED:15569927] [PUBMED:11241670] [PUBMED:11433297] [PUBMED:16709412] [PUBMED:12815057] [PUBMED:14966081] [PUBMED:17086194] [PUBMED:17311277] [PUBMED:14534538] [PUBMED:12398894] [PUBMED:8940113] [PUBMED:17266935] [PUBMED:10652257] [PUBMED:12604616] [PUBMED:14666721] [PUBMED:9045692] [PUBMED:15509650] [PUBMED:11353842] [PUBMED:12791257] [PUBMED:15564375] [PUBMED:12529371] [PUBMED:17409417] [PUBMED:17005551] [PUBMED:12815619] [PUBMED:11997436] [PUBMED:12110689] [PUBMED:17627937]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
N-cadherin signaling events [NCBI:137919] [Pathway Interaction Database:ncadherinpathway] [PUBMED:16319177] [PUBMED:19075000] [PUBMED:15121175] [PUBMED:15226396] [PUBMED:17765222] [PUBMED:7885471] [PUBMED:11086998] [PUBMED:2318342] [PUBMED:8050374] [PUBMED:9655503] [PUBMED:7962102] [PUBMED:7599959] [PUBMED:17459003] [PUBMED:9852580] [PUBMED:9052794] [PUBMED:17005551] [PUBMED:1837087] [PUBMED:1639850] [PUBMED:16176974] [PUBMED:16807326] [PUBMED:15716354] [PUBMED:8707857] [PUBMED:19162191] [PUBMED:12099895] [PUBMED:8113807] [PUBMED:16228908] [PUBMED:17538019] [PUBMED:11056534] [PUBMED:11809840] [PUBMED:11571292] [PUBMED:12377785] [PUBMED:8909549] [PUBMED:3780667] [PUBMED:9655504] [PUBMED:14610057] [PUBMED:15569714] [PUBMED:15662031] [PUBMED:15809310] [PUBMED:15247242] [PUBMED:2762814] [PUBMED:17289573] [PUBMED:17921113] [PUBMED:9712659] [PUBMED:12578907] [PUBMED:16515543] [PUBMED:15034585] [PUBMED:11106648] [PUBMED:11228159] [PUBMED:9786960] [PUBMED:12604612] [PUBMED:11466312] [PUBMED:11238727] [PUBMED:12640032] [PUBMED:1487503] [PUBMED:15383621] [PUBMED:8816706] [PUBMED:17481398] [PUBMED:9545083] [PUBMED:14657280] [PUBMED:12213839] [PUBMED:10930450]
Pathogenic Escherichia coli infection [NCBI:83103] [KEGG:hsa05130] [PUBMED:15318166] [PUBMED:15845459] [PUBMED:19144561] [PUBMED:15694854] [PUBMED:12101285] [PUBMED:15618137] [PUBMED:16582930] [PUBMED:15040260] [PUBMED:16448495]
Proteoglycans in cancer [NCBI:782000] [KEGG:hsa05205] [PUBMED:19433454] [PUBMED:20655987] [PUBMED:18798267] [PUBMED:10633082] [PUBMED:10687947] [PUBMED:22735579] [PUBMED:24412155] [PUBMED:9346940] [PUBMED:22087031] [PUBMED:22194599] [PUBMED:14711376] [PUBMED:19255147] [PUBMED:15655247] [PUBMED:11717317] [PUBMED:17971838] [PUBMED:18413366] [PUBMED:20974860] [PUBMED:11830493] [PUBMED:23058688] [PUBMED:18450475] [PUBMED:12748184] [PUBMED:19733083] [PUBMED:18812315] [PUBMED:12509413] [PUBMED:21155971] [PUBMED:11931647] [PUBMED:18949819] [PUBMED:12729888] [PUBMED:15994311] [PUBMED:23305321] [PUBMED:18505598] [PUBMED:22563565] [PUBMED:22033227]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases activate PAKs [NCBI:1269511] [REACTOME:R-HSA-5627123] [PUBMED:7559638] [PUBMED:9535855] [PUBMED:19513348] [PUBMED:16204230] [PUBMED:10470034] [PUBMED:22340718] [PUBMED:11804587] [PUBMED:21098037] [PUBMED:11278486] [PUBMED:8107774] [PUBMED:10975528]
Shigellosis [NCBI:83104] [KEGG:hsa05131] [PUBMED:11379633] [PUBMED:10491394] [PUBMED:17173036] [PUBMED:18202440] [PUBMED:17095701] [PUBMED:16622194] [PUBMED:16413487] [PUBMED:18005683] [PUBMED:15731041] [PUBMED:15073367] [PUBMED:12856283] [PUBMED:16939534] [PUBMED:17060328] [PUBMED:12065406] [PUBMED:8376337] [PUBMED:11207560] [PUBMED:8642302] [PUBMED:12356723] [PUBMED:15694852] [PUBMED:10369666] [PUBMED:14638419] [PUBMED:16441429] [PUBMED:16162672] [PUBMED:17719540] [PUBMED:7665485] [PUBMED:18059288] [PUBMED:18005697] [PUBMED:19165331] [PUBMED:12828640] [PUBMED:17662586] [PUBMED:9176079] [PUBMED:7591128] [PUBMED:15318166] [PUBMED:15950937]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Syndecan-3-mediated signaling events [NCBI:137952] [Pathway Interaction Database:syndecan_3_pathway] [PUBMED:14504279] [PUBMED:16289473] [PUBMED:12851299] [PUBMED:9133440] [PUBMED:9952400] [PUBMED:12929127] [PUBMED:10460248] [PUBMED:8528141] [PUBMED:9553134] [PUBMED:15198637] [PUBMED:8175719] [PUBMED:16908672] [PUBMED:11461706] [PUBMED:8344959] [PUBMED:16052590] [PUBMED:9660869]
Tight junction [NCBI:83071] [KEGG:hsa04530] [PUBMED:25152334] [PUBMED:16650994] [PUBMED:22892070] [PUBMED:18946474] [PUBMED:12042308] [PUBMED:23885123] [PUBMED:16771626] [PUBMED:17182900] [PUBMED:21283798] [PUBMED:25757376] [PUBMED:22928510] [PUBMED:22169974] [PUBMED:25469537] [PUBMED:24651541] [PUBMED:15820555] [PUBMED:17525755] [PUBMED:27353478] [PUBMED:17950242] [PUBMED:18005931] [PUBMED:24548561] [PUBMED:21781017] [PUBMED:20094051] [PUBMED:20134025] [PUBMED:22896795] [PUBMED:18094055] [PUBMED:25483301]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]