full name
mannan binding lectin serine peptidase 2

synonyms
MAP19, MASP-2, MASP1P1, sMAP, MASP2, ENSG00000009724

HGNC
HGNC:6902

Entrez Gene
Gene:10747

ENSEMBL
ENSG00000009724

location
chr: 1
start: 11086580
stop: 11107296
strand: -

OMIM
OMIM:605102: MASP2
OMIM:613791: MASP2 deficiency

transcripts
NM_006610.3
NM_139208.2

pathways
Complement and coagulation cascades [NCBI:83073] [KEGG:hsa04610] [PUBMED:23564577] [PUBMED:25309880] [PUBMED:26082779] [PUBMED:23110467] [PUBMED:20027185] [PUBMED:25568220] [PUBMED:26324800] [PUBMED:25705421] [PUBMED:21811895] [PUBMED:23911436] [PUBMED:23564578] [PUBMED:24924409] [PUBMED:26489954] [PUBMED:17635716]
Complement cascade [NCBI:1269241] [REACTOME:R-HSA-166658] [PUBMED:3052276] [PUBMED:11044372] [PUBMED:11213801] [PUBMED:15476920] [PUBMED:14698228]
Creation of C4 and C2 activators [NCBI:1269243] [REACTOME:R-HSA-166786] [PUBMED:11044372] [PUBMED:12396008] [PUBMED:70787]
Ficolins bind to repetitive carbohydrate structures on the target cell surface [NCBI:1269245] [REACTOME:R-HSA-2855086] [PUBMED:17544822] [PUBMED:19799112] [PUBMED:11907111] [PUBMED:20375619] [PUBMED:18406375] [PUBMED:11012776] [PUBMED:16116205] [PUBMED:20032467]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Initial triggering of complement [NCBI:1269242] [REACTOME:R-HSA-166663]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Lectin pathway of complement activation [NCBI:1269244] [REACTOME:R-HSA-166662] [PUBMED:11532276]
Staphylococcus aureus infection [NCBI:172846] [KEGG:hsa05150] [PUBMED:18837785] [PUBMED:16679003] [PUBMED:18544012] [PUBMED:15372083] [PUBMED:19112495] [PUBMED:16640587] [PUBMED:15561843] [PUBMED:16322743] [PUBMED:16710608] [PUBMED:16111912] [PUBMED:11361034] [PUBMED:12091905] [PUBMED:16724100] [PUBMED:16242332] [PUBMED:17132726] [PUBMED:20178484] [PUBMED:16086019] [PUBMED:12228315] [PUBMED:19503103] [PUBMED:14993252] [PUBMED:18061675] [PUBMED:17114475] [PUBMED:17848512] [PUBMED:17517597] [PUBMED:20133685] [PUBMED:18045383] [PUBMED:16184199] [PUBMED:17893203] [PUBMED:20062962] [PUBMED:15273292]