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Genes
GAB2
Gene - GAB2
full name
GRB2 associated binding protein 2
synonyms
GAB2, ENSG00000033327
HGNC
HGNC:14458
Entrez Gene
Gene:9846
ENSEMBL
ENSG00000033327
location
chr: 11
start: 77926336
stop: 78128868
strand: -
transcripts
NM_080491.2
NM_012296.3
pathways
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Chronic myeloid leukemia
[NCBI:83116]
[KEGG:hsa05220]
[PUBMED:22286129]
[PUBMED:12801837]
[PUBMED:11160144]
[PUBMED:15719031]
[PUBMED:10403855]
[PUBMED:9834202]
[PUBMED:11071626]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16484590]
[PUBMED:14982876]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
FGFR1 mutant receptor activation
[NCBI:1268865]
[REACTOME:R-HSA-1839124]
[PUBMED:17552943]
[PUBMED:21367659]
[PUBMED:21711248]
[PUBMED:9538690]
[PUBMED:20094046]
[PUBMED:9154000]
Fc epsilon RI signaling pathway
[NCBI:83082]
[KEGG:hsa04664]
[PUBMED:16470226]
[PUBMED:12145654]
[PUBMED:11079101]
[PUBMED:10586892]
[PUBMED:14630197]
[PUBMED:12360215]
[PUBMED:11449275]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Fc gamma R-mediated phagocytosis
[NCBI:114228]
[KEGG:hsa04666]
[PUBMED:11304556]
[PUBMED:11244038]
[PUBMED:10755615]
[PUBMED:17308335]
[PUBMED:12821647]
[PUBMED:15466916]
[PUBMED:17050193]
[PUBMED:11228151]
[PUBMED:12488490]
[PUBMED:10224668]
[PUBMED:11708889]
[PUBMED:9581795]
[PUBMED:10586078]
[PUBMED:9417101]
[PUBMED:15485887]
[PUBMED:18322649]
[PUBMED:10577498]
[PUBMED:10376013]
[PUBMED:10601359]
[PUBMED:9545263]
Fc-epsilon receptor I signaling in mast cells
[NCBI:138050]
[Pathway Interaction Database:fcer1pathway]
[PUBMED:9556577]
[PUBMED:8629002]
[PUBMED:12217401]
[PUBMED:15010370]
[PUBMED:15608142]
[PUBMED:7561053]
[PUBMED:7537741]
[PUBMED:7963537]
[PUBMED:8947047]
[PUBMED:1384468]
[PUBMED:14757742]
[PUBMED:16174756]
[PUBMED:10583594]
[PUBMED:7513150]
[PUBMED:12089510]
[PUBMED:10811803]
[PUBMED:9268346]
[PUBMED:12640123]
[PUBMED:9108083]
[PUBMED:8602265]
[PUBMED:11340169]
[PUBMED:12953098]
[PUBMED:11465115]
[PUBMED:7730640]
[PUBMED:9550384]
[PUBMED:7518558]
[PUBMED:11137136]
[PUBMED:15282299]
[PUBMED:14634134]
[PUBMED:8534912]
[PUBMED:16002993]
[PUBMED:12192036]
[PUBMED:7608202]
[PUBMED:11714805]
[PUBMED:11970986]
[PUBMED:10903718]
[PUBMED:15265912]
[PUBMED:15477350]
G beta:gamma signalling through PI3Kgamma
[NCBI:1269581]
[REACTOME:R-HSA-392451]
[PUBMED:17916723]
[PUBMED:17041586]
G-protein beta:gamma signalling
[NCBI:1269580]
[REACTOME:R-HSA-397795]
[PUBMED:18834311]
GPCR downstream signaling
[NCBI:1269574]
[REACTOME:R-HSA-388396]
[PUBMED:12040175]
GPVI-mediated activation cascade
[NCBI:1269357]
[REACTOME:R-HSA-114604]
[PUBMED:16102042]
[PUBMED:11943772]
Hemostasis
[NCBI:1269340]
[REACTOME:R-HSA-109582]
IL2 signaling events mediated by PI3K
[NCBI:137938]
[Pathway Interaction Database:il2_pi3kpathway]
[PUBMED:15271800]
[PUBMED:8617294]
[PUBMED:7543780]
[PUBMED:9092570]
[PUBMED:9162082]
[PUBMED:7737351]
[PUBMED:9108028]
[PUBMED:11486019]
[PUBMED:1614535]
[PUBMED:15843522]
[PUBMED:7760801]
[PUBMED:9029085]
[PUBMED:1652056]
[PUBMED:11994454]
[PUBMED:12393431]
[PUBMED:9771966]
[PUBMED:10373522]
[PUBMED:12525482]
[PUBMED:3523754]
[PUBMED:7736574]
[PUBMED:10982827]
[PUBMED:7589144]
[PUBMED:7528328]
IL2 signaling events mediated by STAT5
[NCBI:137988]
[Pathway Interaction Database:il2_stat5pathway]
[PUBMED:11160217]
[PUBMED:16645171]
[PUBMED:9121484]
[PUBMED:17182565]
[PUBMED:14607901]
[PUBMED:9104808]
[PUBMED:11485747]
[PUBMED:14614860]
[PUBMED:10679091]
[PUBMED:12196288]
[PUBMED:10072077]
[PUBMED:10544201]
[PUBMED:15004274]
[PUBMED:9390691]
[PUBMED:9395528]
[PUBMED:10514006]
[PUBMED:14500638]
[PUBMED:16757175]
[PUBMED:9541574]
[PUBMED:8617294]
IL2-mediated signaling events
[NCBI:137976]
[Pathway Interaction Database:il2_1pathway]
[PUBMED:7568005]
[PUBMED:10962026]
[PUBMED:1545122]
[PUBMED:10602027]
[PUBMED:15170389]
[PUBMED:9092570]
[PUBMED:7509794]
[PUBMED:15356145]
[PUBMED:9973481]
[PUBMED:10899310]
[PUBMED:9195132]
[PUBMED:7544001]
[PUBMED:7777534]
[PUBMED:12681450]
[PUBMED:7665592]
[PUBMED:8702919]
[PUBMED:1708096]
[PUBMED:8643566]
[PUBMED:7988557]
[PUBMED:7737351]
[PUBMED:1532814]
[PUBMED:8262551]
[PUBMED:8025955]
[PUBMED:10993906]
[PUBMED:3095922]
[PUBMED:8805624]
[PUBMED:9391116]
[PUBMED:7973658]
[PUBMED:11331873]
[PUBMED:10421845]
[PUBMED:8119884]
[PUBMED:7781605]
[PUBMED:12543077]
[PUBMED:9133424]
[PUBMED:1618313]
[PUBMED:1940342]
[PUBMED:9382798]
[PUBMED:10514520]
[PUBMED:7973659]
[PUBMED:1639773]
[PUBMED:9029085]
[PUBMED:7760801]
[PUBMED:1460037]
[PUBMED:9202126]
[PUBMED:1652056]
[PUBMED:12393431]
[PUBMED:8397196]
[PUBMED:2047859]
[PUBMED:7688728]
[PUBMED:8700888]
[PUBMED:7528668]
[PUBMED:9305919]
[PUBMED:2303462]
[PUBMED:7568001]
[PUBMED:9822600]
[PUBMED:7543676]
[PUBMED:7499365]
[PUBMED:10843677]
[PUBMED:7600304]
[PUBMED:7719937]
[PUBMED:9590209]
[PUBMED:9794391]
[PUBMED:10849428]
[PUBMED:8294403]
[PUBMED:10373548]
[PUBMED:2590941]
[PUBMED:9512511]
[PUBMED:6434688]
[PUBMED:9697832]
[PUBMED:10982827]
[PUBMED:10214954]
[PUBMED:10825200]
[PUBMED:1535827]
[PUBMED:10369681]
[PUBMED:7719938]
[PUBMED:1655887]
[PUBMED:8376945]
[PUBMED:1996324]
[PUBMED:7479881]
[PUBMED:10962581]
[PUBMED:7973657]
[PUBMED:1631559]
[PUBMED:10066828]
[PUBMED:9169478]
[PUBMED:8552611]
[PUBMED:8483935]
[PUBMED:2106566]
[PUBMED:16199887]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Interleukin receptor SHC signaling
[NCBI:1269322]
[REACTOME:R-HSA-912526]
[PUBMED:8294403]
Interleukin-2 signaling
[NCBI:1269321]
[REACTOME:R-HSA-451927]
[PUBMED:17936914]
[PUBMED:18817510]
[PUBMED:19543225]
[PUBMED:18062768]
Interleukin-3, 5 and GM-CSF signaling
[NCBI:1269323]
[REACTOME:R-HSA-512988]
[PUBMED:10450743]
[PUBMED:9766809]
Neurotrophic factor-mediated Trk receptor signaling
[NCBI:137977]
[Pathway Interaction Database:trkrpathway]
[PUBMED:1849459]
[PUBMED:8226808]
[PUBMED:11163269]
[PUBMED:7510697]
[PUBMED:11027277]
[PUBMED:15758069]
[PUBMED:11425862]
[PUBMED:11238898]
[PUBMED:11251075]
[PUBMED:8344249]
[PUBMED:9356464]
[PUBMED:11150291]
[PUBMED:10092678]
[PUBMED:1280261]
[PUBMED:11150334]
[PUBMED:11244088]
[PUBMED:10985348]
[PUBMED:15753086]
[PUBMED:1653651]
[PUBMED:11466412]
[PUBMED:15167895]
[PUBMED:1831195]
[PUBMED:10490030]
[PUBMED:8384556]
[PUBMED:16697063]
[PUBMED:17003042]
[PUBMED:15520226]
[PUBMED:15632082]
[PUBMED:16611639]
[PUBMED:16187212]
[PUBMED:9182757]
[PUBMED:1604323]
[PUBMED:16284401]
[PUBMED:8356095]
[PUBMED:10329710]
[PUBMED:9927421]
[PUBMED:9856458]
[PUBMED:10691301]
[PUBMED:1375038]
[PUBMED:10679771]
[PUBMED:15122257]
[PUBMED:15513915]
[PUBMED:16701206]
[PUBMED:1710174]
[PUBMED:8155326]
[PUBMED:8288573]
[PUBMED:7972023]
[PUBMED:7512734]
[PUBMED:10601297]
[PUBMED:16203995]
[PUBMED:12510192]
[PUBMED:16481401]
[PUBMED:8106527]
[PUBMED:11278445]
[PUBMED:9099755]
[PUBMED:1850821]
[PUBMED:9632781]
[PUBMED:10235685]
[PUBMED:15917464]
[PUBMED:9285826]
[PUBMED:12446789]
[PUBMED:7657612]
[PUBMED:1850549]
[PUBMED:12879077]
[PUBMED:16157584]
[PUBMED:10207144]
[PUBMED:12006576]
[PUBMED:8052307]
[PUBMED:8382740]
[PUBMED:10629055]
Osteoclast differentiation
[NCBI:193147]
[KEGG:hsa04380]
[PUBMED:17633024]
[PUBMED:18382763]
[PUBMED:18329366]
[PUBMED:17869613]
[PUBMED:18722561]
[PUBMED:15122243]
[PUBMED:20703218]
[PUBMED:12748652]
[PUBMED:12110142]
[PUBMED:19585227]
[PUBMED:15546140]
[PUBMED:16184196]
[PUBMED:15817678]
[PUBMED:20392226]
[PUBMED:16313349]
[PUBMED:16313342]
[PUBMED:17380158]
[PUBMED:18451259]
Phospholipase D signaling pathway
[NCBI:1311074]
[KEGG:hsa04072]
[PUBMED:9310372]
[PUBMED:9119890]
[PUBMED:15310762]
[PUBMED:18936782]
[PUBMED:24990952]
[PUBMED:14769825]
[PUBMED:21936578]
[PUBMED:10666319]
[PUBMED:17210675]
[PUBMED:19264150]
[PUBMED:23076158]
[PUBMED:17054901]
[PUBMED:16622417]
[PUBMED:10807766]
[PUBMED:12217395]
[PUBMED:11042115]
[PUBMED:19815110]
[PUBMED:24995811]
[PUBMED:16143829]
[PUBMED:8135758]
[PUBMED:11991733]
[PUBMED:19410013]
[PUBMED:17245604]
Platelet activation, signaling and aggregation
[NCBI:1269350]
[REACTOME:R-HSA-76002]
[PUBMED:16543958]
[PUBMED:8704248]
[PUBMED:2018971]
[PUBMED:1672265]
[PUBMED:17059469]
[PUBMED:12681240]
[PUBMED:12411949]
[PUBMED:11511514]
RET signaling
[NCBI:1427866]
[REACTOME:R-HSA-8853659]
[PUBMED:15013219]
[PUBMED:17036197]
Ras signaling pathway
[NCBI:868085]
[KEGG:hsa04014]
[PUBMED:23506953]
[PUBMED:18437264]
[PUBMED:15062121]
[PUBMED:22189424]
[PUBMED:22233291]
[PUBMED:12778136]
[PUBMED:11313946]
[PUBMED:17428555]
[PUBMED:19091743]
[PUBMED:18568040]
[PUBMED:20420946]
[PUBMED:12217381]
[PUBMED:14663478]
[PUBMED:21686117]
[PUBMED:12642680]
[PUBMED:21196257]
[PUBMED:16869784]
[PUBMED:21111786]
[PUBMED:16966426]
[PUBMED:10712923]
[PUBMED:22020205]
[PUBMED:17384584]
[PUBMED:15572660]
[PUBMED:18413813]
Role of LAT2/NTAL/LAB on calcium mobilization
[NCBI:1269302]
[REACTOME:R-HSA-2730905]
[PUBMED:17993265]
[PUBMED:20643813]
[PUBMED:17420272]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by FGFR in disease
[NCBI:1268863]
[REACTOME:R-HSA-1226099]
[PUBMED:17552943]
[PUBMED:10053006]
[PUBMED:8640234]
[PUBMED:9865713]
[PUBMED:21367659]
[PUBMED:10471491]
[PUBMED:21711248]
[PUBMED:9538690]
[PUBMED:20094046]
[PUBMED:9539778]
[PUBMED:12461689]
[PUBMED:9438390]
[PUBMED:8841188]
[PUBMED:11055896]
[PUBMED:8599935]
[PUBMED:21160078]
[PUBMED:9207791]
[PUBMED:9154000]
[PUBMED:18381441]
[PUBMED:20179196]
[PUBMED:8755573]
[PUBMED:20226962]
[PUBMED:8798788]
[PUBMED:19066716]
[PUBMED:17505008]
[PUBMED:11429702]
Signaling by FGFR1 in disease
[NCBI:1268864]
[REACTOME:R-HSA-5655302]
[PUBMED:24588013]
[PUBMED:20094046]
[PUBMED:18056464]
[PUBMED:18772890]
[PUBMED:14613973]
[PUBMED:7874169]
[PUBMED:9154000]
[PUBMED:20226962]
[PUBMED:16140923]
[PUBMED:17552943]
[PUBMED:21367659]
[PUBMED:21711248]
[PUBMED:9538690]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Signaling by SCF-KIT
[NCBI:1269487]
[REACTOME:R-HSA-1433557]
[PUBMED:17350321]
[PUBMED:16483568]
[PUBMED:7688988]
[PUBMED:19540337]
[PUBMED:16475976]
[PUBMED:15526160]
Signaling by cytosolic FGFR1 fusion mutants
[NCBI:1268867]
[REACTOME:R-HSA-1839117]
[PUBMED:20226962]
[PUBMED:17698633]
[PUBMED:21330321]
[PUBMED:11689702]
[PUBMED:21367659]
[PUBMED:21711248]
[PUBMED:10480903]
[PUBMED:18412956]
[PUBMED:11739186]
[PUBMED:15050920]
[PUBMED:20094046]
[PUBMED:10935490]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
[NCBI:137930]
[Pathway Interaction Database:met_pathway]
[PUBMED:10793146]
[PUBMED:8906793]
[PUBMED:11929826]
[PUBMED:10022866]
[PUBMED:11532961]
[PUBMED:12475979]
[PUBMED:1718989]
[PUBMED:1846706]
[PUBMED:10970810]
[PUBMED:10516287]
[PUBMED:12138161]
[PUBMED:11046147]
[PUBMED:18073207]
[PUBMED:12951049]
[PUBMED:15494312]
[PUBMED:9001234]
[PUBMED:11352916]
[PUBMED:11896055]
[PUBMED:9440692]
[PUBMED:8607979]
[PUBMED:12244132]
[PUBMED:11162460]
[PUBMED:11809798]
[PUBMED:9693375]
[PUBMED:14636584]
[PUBMED:17297451]
[PUBMED:17682062]
[PUBMED:19628037]
[PUBMED:11069926]
[PUBMED:18819921]
[PUBMED:16423831]
[PUBMED:10558875]
[PUBMED:16858414]
[PUBMED:10995442]
[PUBMED:20332103]
[PUBMED:11146548]
[PUBMED:18346875]
[PUBMED:17894413]
[PUBMED:9252406]
[PUBMED:17635922]
[PUBMED:11134526]
[PUBMED:2005882]
[PUBMED:19609305]
[PUBMED:8380735]
[PUBMED:16537482]
[PUBMED:10618718]
[PUBMED:9591773]
[PUBMED:12894582]
[PUBMED:9748249]
[PUBMED:11741535]
[PUBMED:17881575]
[PUBMED:10713050]
[PUBMED:1655790]
[PUBMED:11784715]
[PUBMED:10753869]
[PUBMED:10713700]
[PUBMED:11118451]
[PUBMED:16952352]
[PUBMED:15314156]
[PUBMED:19272169]
[PUBMED:12802068]
[PUBMED:17363898]
[PUBMED:7513258]
[PUBMED:1827664]
[PUBMED:2541345]
[PUBMED:8387483]
[PUBMED:16620780]
[PUBMED:11445578]
[PUBMED:10734310]
[PUBMED:16227611]
[PUBMED:12941962]
[PUBMED:15735664]
[PUBMED:19071214]
[PUBMED:7731718]
[PUBMED:19289496]
[PUBMED:11438654]
[PUBMED:11896612]
[PUBMED:11894096]
[PUBMED:11896575]
[PUBMED:7499247]
[PUBMED:12147692]
[PUBMED:11948414]
[PUBMED:19881549]
[PUBMED:19525225]
[PUBMED:14684163]
[PUBMED:17055484]
[PUBMED:9668053]
[PUBMED:10531383]
[PUBMED:9681449]
[PUBMED:1655405]
[PUBMED:12686592]
[PUBMED:19109251]
[PUBMED:10679787]
[PUBMED:9487126]
[PUBMED:9886295]
[PUBMED:12058075]
[PUBMED:15452053]
[PUBMED:9184210]
[PUBMED:10871282]
[PUBMED:17329361]
[PUBMED:2554238]
Sphingolipid signaling pathway
[NCBI:1144995]
[KEGG:hsa04071]
[PUBMED:23919551]
[PUBMED:21705677]
[PUBMED:18675379]
[PUBMED:20534702]
[PUBMED:15999095]
[PUBMED:16470226]
[PUBMED:11001563]
[PUBMED:17913601]
[PUBMED:17161984]
[PUBMED:22654878]
[PUBMED:17438574]
[PUBMED:18216770]
[PUBMED:11418646]
[PUBMED:10880336]
[PUBMED:15451787]
[PUBMED:25309325]
[PUBMED:18403224]
TCR signaling in naive CD4+ T cells
[NCBI:137998]
[Pathway Interaction Database:tcr_pathway]
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