full name
glutamate metabotropic receptor 5

synonyms
GPRC1E, mGlu5, MGLUR5, GRM5, ENSG00000168959

HGNC
HGNC:4597

Entrez Gene
Gene:2915

ENSEMBL
ENSG00000168959

location
chr: 11
start: 88237256
stop: 88796846
strand: -

transcripts
NM_000842.3
NM_001143831.2

pathways
Calcium signaling pathway [NCBI:83050] [KEGG:hsa04020] [PUBMED:11080247] [PUBMED:14572802] [PUBMED:11413485] [PUBMED:22129055] [PUBMED:10508738] [PUBMED:15000521] [PUBMED:9235901] [PUBMED:7861177] [PUBMED:9149541] [PUBMED:14517314] [PUBMED:15111104] [PUBMED:11698232] [PUBMED:10331643] [PUBMED:12838335] [PUBMED:8125957] [PUBMED:19172794] [PUBMED:10997573] [PUBMED:21338471] [PUBMED:11299192] [PUBMED:22002090] [PUBMED:12972622]
Class C/3 (Metabotropic glutamate/pheromone receptors) [NCBI:1269573] [REACTOME:R-HSA-420499] [PUBMED:12782243] [PUBMED:17266540]
G alpha (q) signalling events [NCBI:1269578] [REACTOME:R-HSA-416476] [PUBMED:19212139]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Gap junction [NCBI:83072] [KEGG:hsa04540] [PUBMED:9535909] [PUBMED:15033578] [PUBMED:12566218] [PUBMED:14506308] [PUBMED:10751659] [PUBMED:10873290] [PUBMED:15955302] [PUBMED:15033579] [PUBMED:15033580] [PUBMED:15094344]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
Glutamatergic synapse [NCBI:213818] [KEGG:hsa04724] [PUBMED:10481192] [PUBMED:11561058] [PUBMED:18425072] [PUBMED:17706608] [PUBMED:20055706] [PUBMED:19112153] [PUBMED:17663464] [PUBMED:19110202] [PUBMED:19559598] [PUBMED:9665875] [PUBMED:11672421] [PUBMED:18464791] [PUBMED:12399578] [PUBMED:14684436]
Huntington's disease [NCBI:83100] [KEGG:hsa05016] [PUBMED:15336977] [PUBMED:11738471] [PUBMED:11807533] [PUBMED:15996546] [PUBMED:14526190] [PUBMED:15242639] [PUBMED:17041811] [PUBMED:15996541] [PUBMED:18951640] [PUBMED:15459747] [PUBMED:16288298] [PUBMED:17081970] [PUBMED:15695335] [PUBMED:12372277] [PUBMED:11839795]
Interactions of neurexins and neuroligins at synapses [NCBI:1427850] [REACTOME:R-HSA-6794361] [PUBMED:22424845] [PUBMED:23559421] [PUBMED:21155806] [PUBMED:17299456] [PUBMED:17275284]
Long-term potentiation [NCBI:83085] [KEGG:hsa04720] [PUBMED:9697848] [PUBMED:15652868] [PUBMED:15803158] [PUBMED:11378299] [PUBMED:10652548] [PUBMED:15857686] [PUBMED:14715912]
Neuroactive ligand-receptor interaction [NCBI:83053] [KEGG:hsa04080]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Phospholipase D signaling pathway [NCBI:1311074] [KEGG:hsa04072] [PUBMED:9310372] [PUBMED:9119890] [PUBMED:15310762] [PUBMED:18936782] [PUBMED:24990952] [PUBMED:14769825] [PUBMED:21936578] [PUBMED:10666319] [PUBMED:17210675] [PUBMED:19264150] [PUBMED:23076158] [PUBMED:17054901] [PUBMED:16622417] [PUBMED:10807766] [PUBMED:12217395] [PUBMED:11042115] [PUBMED:19815110] [PUBMED:24995811] [PUBMED:16143829] [PUBMED:8135758] [PUBMED:11991733] [PUBMED:19410013] [PUBMED:17245604]
Protein-protein interactions at synapses [NCBI:1427849] [REACTOME:R-HSA-6794362] [PUBMED:18923512] [PUBMED:16337696] [PUBMED:17299456]
Retrograde endocannabinoid signaling [NCBI:537443] [KEGG:hsa04723] [PUBMED:16085309] [PUBMED:18515270] [PUBMED:15340387] [PUBMED:17636069] [PUBMED:17553427] [PUBMED:17404373] [PUBMED:19640475] [PUBMED:21117095] [PUBMED:18084639] [PUBMED:21187849] [PUBMED:18801434] [PUBMED:14978245] [PUBMED:21531987] [PUBMED:19553483] [PUBMED:19126760] [PUBMED:17419048] [PUBMED:18948642] [PUBMED:16968947]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]