full name
matrix metallopeptidase 3

synonyms
CHDS6, MMP-3, SL-1, STMY, STMY1, STR1, MMP3, ENSG00000149968

HGNC
HGNC:7173

Entrez Gene
Gene:4314

ENSEMBL
ENSG00000149968
ENSG00000263313

location
chr: 11
start: 102706528
stop: 102714342
strand: -

OMIM
OMIM:185250: MMP3
OMIM:614466: {Coronary heart disease, susceptibility to, 6}

transcripts
NM_002422.3

pathways
Activation of Matrix Metalloproteinases [NCBI:1270258] [REACTOME:R-HSA-1592389] [PUBMED:19817485] [PUBMED:19616423] [PUBMED:19800373] [PUBMED:17562450]
Assembly of collagen fibrils and other multimeric structures [NCBI:1270247] [REACTOME:R-HSA-2022090] [PUBMED:8645190] [PUBMED:21182410]
Collagen degradation [NCBI:1270259] [REACTOME:R-HSA-1442490] [PUBMED:11076937] [PUBMED:21087458] [PUBMED:9818170]
Collagen formation [NCBI:1270245] [REACTOME:R-HSA-1474290] [PUBMED:7574488] [PUBMED:19693541]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Degradation of the extracellular matrix [NCBI:1270257] [REACTOME:R-HSA-1474228] [PUBMED:21917992]
EGFR Transactivation by Gastrin [NCBI:1269593] [REACTOME:R-HSA-2179392] [PUBMED:16816139] [PUBMED:20398727]
Extracellular matrix organization [NCBI:1270244] [REACTOME:R-HSA-1474244] [PUBMED:21123617] [PUBMED:21917992] [PUBMED:12845610]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
IL-17 signaling pathway [NCBI:1474301] [KEGG:hsa04657] [PUBMED:17921324] [PUBMED:24011563] [PUBMED:21349428] [PUBMED:20383173] [PUBMED:20514051] [PUBMED:20177959] [PUBMED:18178098] [PUBMED:21074482] [PUBMED:21130872] [PUBMED:17027518] [PUBMED:23917206] [PUBMED:23116200] [PUBMED:18701318] [PUBMED:26252407] [PUBMED:22851696] [PUBMED:21155836] [PUBMED:25145755] [PUBMED:17177681] [PUBMED:19575028] [PUBMED:23557798] [PUBMED:21852080] [PUBMED:22324470]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Interleukin-4 and 13 signaling [NCBI:1470923] [REACTOME:R-HSA-6785807] [PUBMED:12704343] [PUBMED:10358772]
Rheumatoid arthritis [NCBI:200309] [KEGG:hsa05323] [PUBMED:9627005] [PUBMED:17195034] [PUBMED:15059264] [PUBMED:17380158] [PUBMED:20651747] [PUBMED:19455385] [PUBMED:20305562] [PUBMED:20510236] [PUBMED:19184540] [PUBMED:20392226] [PUBMED:17502360] [PUBMED:16313349] [PUBMED:16127012] [PUBMED:15055519] [PUBMED:20036936] [PUBMED:11861618] [PUBMED:19585227] [PUBMED:20193003]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
TNF signaling pathway [NCBI:812256] [KEGG:hsa04668] [PUBMED:20489699] [PUBMED:14532286] [PUBMED:21232019] [PUBMED:11897488] [PUBMED:22296764] [PUBMED:10581243] [PUBMED:23085193] [PUBMED:23531747]
Transcriptional misregulation in cancer [NCBI:523016] [KEGG:hsa05202] [PUBMED:17327229] [PUBMED:20190806] [PUBMED:20145147] [PUBMED:11313274] [PUBMED:11863357] [PUBMED:19472090] [PUBMED:18330902] [PUBMED:19738075] [PUBMED:15024077] [PUBMED:12032780] [PUBMED:14630078] [PUBMED:21765642] [PUBMED:19564705] [PUBMED:17101797] [PUBMED:15160934] [PUBMED:15688424] [PUBMED:15985538] [PUBMED:12527902] [PUBMED:12511414] [PUBMED:11607818] [PUBMED:17222504] [PUBMED:15826838] [PUBMED:21747944] [PUBMED:19406209] [PUBMED:10350329] [PUBMED:21779514] [PUBMED:18563191] [PUBMED:16946003] [PUBMED:17250957] [PUBMED:12670461] [PUBMED:12529654] [PUBMED:18855877] [PUBMED:17505060] [PUBMED:20153925] [PUBMED:20490326] [PUBMED:12130514] [PUBMED:18648544] [PUBMED:19855079] [PUBMED:10717473] [PUBMED:20478527] [PUBMED:11340171] [PUBMED:16169901] [PUBMED:14998494] [PUBMED:19233641] [PUBMED:19133982] [PUBMED:12393465] [PUBMED:19059936] [PUBMED:18172298] [PUBMED:10500199] [PUBMED:19141473] [PUBMED:10537274] [PUBMED:15156184] [PUBMED:14701735] [PUBMED:19422821] [PUBMED:21518926] [PUBMED:18850010] [PUBMED:19075677] [PUBMED:18457914] [PUBMED:12527906] [PUBMED:15644444] [PUBMED:10784387] [PUBMED:17024155] [PUBMED:19075268] [PUBMED:15826834] [PUBMED:21849159] [PUBMED:21123453] [PUBMED:20974671] [PUBMED:20863376]
p75(NTR)-mediated signaling [NCBI:138019] [Pathway Interaction Database:p75ntrpathway] [PUBMED:14673001] [PUBMED:14593116] [PUBMED:10545116] [PUBMED:11729324] [PUBMED:16252010] [PUBMED:11756426] [PUBMED:12414813] [PUBMED:2157470] [PUBMED:11777929] [PUBMED:1547788] [PUBMED:10764727] [PUBMED:8614802] [PUBMED:14960584] [PUBMED:12376548] [PUBMED:11756498] [PUBMED:8079174] [PUBMED:16498402] [PUBMED:15051733] [PUBMED:12682012] [PUBMED:14638693] [PUBMED:14966521] [PUBMED:9915784] [PUBMED:11487608] [PUBMED:10485890] [PUBMED:16630834] [PUBMED:11312266] [PUBMED:10985348] [PUBMED:11244088] [PUBMED:6093111] [PUBMED:10595511] [PUBMED:14985763] [PUBMED:12097334] [PUBMED:15548667] [PUBMED:15470142] [PUBMED:11279271] [PUBMED:8878481] [PUBMED:12422217] [PUBMED:15987945] [PUBMED:15668238] [PUBMED:10433815] [PUBMED:12692556] [PUBMED:2025430] [PUBMED:15930396] [PUBMED:11278287] [PUBMED:12034707]