full name
acetyl-CoA acetyltransferase 1

synonyms
ACAT, MAT, T2, THIL, ACAT1, ENSG00000075239

HGNC
HGNC:93

Entrez Gene
Gene:38

ENSEMBL
ENSG00000075239

location
chr: 11
start: 107992258
stop: 108018895
strand: +

OMIM
OMIM:607809: ACAT1 (Autosomal recessive inheritance)
OMIM:203750: Alpha-methylacetoacetic aciduria

transcripts
NM_000019.3

pathways
Branched-chain amino acid catabolism [NCBI:1270161] [REACTOME:R-HSA-70895]
Butanoate metabolism [NCBI:83007] [KEGG:hsa00650]
C5 isoprenoid biosynthesis, mevalonate pathway [NCBI:413387] [KEGG:hsa_M00095]
Carbon metabolism [NCBI:814926] [KEGG:hsa01200]
Fatty acid degradation [NCBI:82935] [KEGG:hsa00071] [PUBMED:869535]
Fatty acid metabolism [NCBI:868084] [KEGG:hsa01212]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Glyoxylate and dicarboxylate metabolism [NCBI:83002] [KEGG:hsa00630] [PUBMED:10978349] [PUBMED:16407450] [PUBMED:11513957] [PUBMED:18065535] [PUBMED:21252347] [PUBMED:9596633] [PUBMED:18819910]
Ketone body metabolism [NCBI:1270026] [REACTOME:R-HSA-74182] [PUBMED:21479626]
Lysine degradation [NCBI:82956] [KEGG:hsa00310] [PUBMED:11802770] [PUBMED:1682209]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Propanoate metabolism [NCBI:83004] [KEGG:hsa00640]
Pyruvate metabolism [NCBI:82998] [KEGG:hsa00620] [NCBI:1270123] [REACTOME:R-HSA-70268] [PUBMED:2188967] [PUBMED:7273846]
Synthesis and degradation of ketone bodies [NCBI:82936] [KEGG:hsa00072]
Synthesis of Ketone Bodies [NCBI:1270027] [REACTOME:R-HSA-77111] [PUBMED:21479626]
Terpenoid backbone biosynthesis [NCBI:83022] [KEGG:hsa00900] [PUBMED:12777052] [PUBMED:9858571] [PUBMED:16262699] [PUBMED:24375100]
Tryptophan metabolism [NCBI:82964] [KEGG:hsa00380] [PUBMED:15749753]
Utilization of Ketone Bodies [NCBI:1270028] [REACTOME:R-HSA-77108] [PUBMED:21479626]
Valine, leucine and isoleucine degradation [NCBI:82952] [KEGG:hsa00280]
glutaryl-CoA degradation [NCBI:142409] [BIOCYC:HUMAN_PWY-5177] [PUBMED:8436125] [PUBMED:11705404]
isoleucine degradation [NCBI:142358] [BIOCYC:HUMAN_ILEUDEG-PWY] [PUBMED:4150713] [PUBMED:773366]
ketogenesis [NCBI:545368] [BIOCYC:HUMAN_PWY66-367] [PUBMED:12364542] [PUBMED:9727714] [PUBMED:14769483] [PUBMED:10031425] [PUBMED:18668440] [PUBMED:1196305] [PUBMED:8027038] [PUBMED:17371050] [PUBMED:20491249]
ketolysis [NCBI:545369] [BIOCYC:HUMAN_PWY66-368] [PUBMED:16380372] [PUBMED:16584562] [PUBMED:18845187] [PUBMED:15048898] [PUBMED:18668440] [PUBMED:15953344] [PUBMED:14769483] [PUBMED:12975474]
mevalonate pathway [NCBI:142207] [BIOCYC:HUMAN_PWY-922]
superpathway of cholesterol biosynthesis [NCBI:142269] [BIOCYC:HUMAN_PWY66-5] [PUBMED:240818] [PUBMED:11519011] [PUBMED:9634533] [PUBMED:10666321] [PUBMED:14766201] [PUBMED:9465114] [PUBMED:10710235] [PUBMED:9683613] [PUBMED:12133002] [PUBMED:9894009] [PUBMED:12618959] [PUBMED:3037232] [PUBMED:2614264] [PUBMED:9630650] [PUBMED:10391219] [PUBMED:12829805] [PUBMED:2007571] [PUBMED:9653161]
superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) [NCBI:545288] [BIOCYC:HUMAN_PWY-5910]