full name
mechanistic target of rapamycin

synonyms
FRAP, FRAP1, FRAP2, RAFT1, RAPT1, MTOR, ENSG00000198793

HGNC
HGNC:3942

Entrez Gene
Gene:2475

ENSEMBL
ENSG00000198793

location
chr: 1
start: 11166588
stop: 11322614
strand: -

OMIM
OMIM:601231: MTOR
OMIM:607341: Focal cortical dysplasia, type II, somatic
OMIM:616638: Smith-Kingsmore syndrome

transcripts
NM_004958.3

pathways
AMPK signaling [NCBI:198868] [WikiPathways:WP1403] [PUBMED:12392881] [PUBMED:16364253] [PUBMED:19596898] [PUBMED:19098422] [PUBMED:14651849] [PUBMED:16105857] [PUBMED:2567185] [PUBMED:16479585] [PUBMED:15661536] [PUBMED:9472019] [PUBMED:16027121] [PUBMED:11069105] [PUBMED:12740371] [PUBMED:19245654] [PUBMED:12502487] [PUBMED:18328803]
AMPK signaling pathway [NCBI:989139] [KEGG:hsa04152] [PUBMED:22885100] [PUBMED:19724019] [PUBMED:19584320] [PUBMED:16644802] [PUBMED:16479585] [PUBMED:20010958] [PUBMED:20357764] [PUBMED:23565491] [PUBMED:19197243] [PUBMED:16723978] [PUBMED:16054041] [PUBMED:19393004] [PUBMED:17307971] [PUBMED:23899560] [PUBMED:23024365] [PUBMED:15509864] [PUBMED:23747347] [PUBMED:18725075] [PUBMED:22700795] [PUBMED:19629071]
Acute myeloid leukemia [NCBI:83117] [KEGG:hsa05221] [PUBMED:16236521] [PUBMED:12951584] [PUBMED:16352814] [PUBMED:16146838] [PUBMED:16642045] [PUBMED:11721960] [PUBMED:15625120] [PUBMED:17554387] [PUBMED:12563308] [PUBMED:12468433]
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:21682741] [PUBMED:16551257] [PUBMED:11861602]
Adipocytokine signaling pathway [NCBI:83093] [KEGG:hsa04920] [PUBMED:12829246] [PUBMED:10905472] [PUBMED:15980064] [PUBMED:12754525] [PUBMED:12368907] [PUBMED:11557972] [PUBMED:15856064] [PUBMED:10766253] [PUBMED:9671776] [PUBMED:14679176] [PUBMED:15733744] [PUBMED:15058305] [PUBMED:11479627] [PUBMED:14716305]
Alpha6-Beta4 Integrin Signaling Pathway [NCBI:198807] [WikiPathways:WP244]
BDNF signaling pathway [NCBI:712093] [WikiPathways:WP2380] [PUBMED:11980901] [PUBMED:8760293] [PUBMED:11922610] [PUBMED:18422784] [PUBMED:7780132] [PUBMED:11054408] [PUBMED:15504554] [PUBMED:12036856] [PUBMED:17658515] [PUBMED:11722433] [PUBMED:22809535] [PUBMED:20870899] [PUBMED:9070265] [PUBMED:9506832] [PUBMED:10979953] [PUBMED:9305885] [PUBMED:15701720] [PUBMED:8695859] [PUBMED:11204567] [PUBMED:15588513] [PUBMED:19261614] [PUBMED:10611229] [PUBMED:7589510] [PUBMED:10651727] [PUBMED:9711904] [PUBMED:10224114] [PUBMED:16123382] [PUBMED:9373250] [PUBMED:12855555] [PUBMED:11085749] [PUBMED:11750880] [PUBMED:10918061] [PUBMED:9257862] [PUBMED:18256550] [PUBMED:10460590] [PUBMED:21898686] [PUBMED:16368886] [PUBMED:18528423] [PUBMED:10415383] [PUBMED:22456226] [PUBMED:11784712] [PUBMED:11278373] [PUBMED:15673499] [PUBMED:14576181] [PUBMED:21304100] [PUBMED:18618018] [PUBMED:14687665] [PUBMED:10438715] [PUBMED:12495897] [PUBMED:19744539] [PUBMED:7795229] [PUBMED:9119889] [PUBMED:8632906] [PUBMED:11402314] [PUBMED:8843545] [PUBMED:21892137] [PUBMED:7545904] [PUBMED:19289146] [PUBMED:20576130] [PUBMED:18804163] [PUBMED:19888469] [PUBMED:8695851] [PUBMED:10419886] [PUBMED:19714753] [PUBMED:11238104] [PUBMED:11266445] [PUBMED:15705785] [PUBMED:16249382] [PUBMED:19038790] [PUBMED:15778351] [PUBMED:22514603] [PUBMED:9632812] [PUBMED:9446641] [PUBMED:9990315] [PUBMED:11861812] [PUBMED:20838657] [PUBMED:19619605] [PUBMED:11830463] [PUBMED:17244674] [PUBMED:8877093] [PUBMED:11418622] [PUBMED:9654143] [PUBMED:9111365] [PUBMED:21490406] [PUBMED:9396763] [PUBMED:15001470] [PUBMED:10477685] [PUBMED:11567993] [PUBMED:11376873] [PUBMED:15863506] [PUBMED:10090948] [PUBMED:21900501] [PUBMED:11429396] [PUBMED:18060035] [PUBMED:19631713] [PUBMED:11756417] [PUBMED:9120001] [PUBMED:8628315] [PUBMED:11110685] [PUBMED:11500082] [PUBMED:21630326] [PUBMED:15271795] [PUBMED:17021950] [PUBMED:10194437] [PUBMED:11389697] [PUBMED:10361118] [PUBMED:11535599] [PUBMED:9475764] [PUBMED:7649975] [PUBMED:22649382] [PUBMED:9002950] [PUBMED:10803464] [PUBMED:16418722] [PUBMED:18796624] [PUBMED:15671147] [PUBMED:11446731] [PUBMED:19996410] [PUBMED:20502002] [PUBMED:17284614] [PUBMED:9679986] [PUBMED:20586925] [PUBMED:12032335] [PUBMED:20335227] [PUBMED:8549784] [PUBMED:20976181] [PUBMED:10321988] [PUBMED:17827152] [PUBMED:18288130] [PUBMED:9108397] [PUBMED:18456388] [PUBMED:14617636] [PUBMED:10681535] [PUBMED:11934880] [PUBMED:7488109] [PUBMED:17925492] [PUBMED:15642952] [PUBMED:12359731] [PUBMED:10205146] [PUBMED:21853157] [PUBMED:12145691] [PUBMED:16115772] [PUBMED:21325822] [PUBMED:11012189] [PUBMED:9663467] [PUBMED:9108383] [PUBMED:21933853] [PUBMED:8978680] [PUBMED:18487512] [PUBMED:22005786] [PUBMED:11309383] [PUBMED:11964286] [PUBMED:15085152] [PUBMED:17980909] [PUBMED:9731041] [PUBMED:22528490] [PUBMED:10515871] [PUBMED:21527831] [PUBMED:17525997] [PUBMED:6325330] [PUBMED:20113333] [PUBMED:11283246] [PUBMED:17637498] [PUBMED:14662334] [PUBMED:10050883] [PUBMED:14576068] [PUBMED:7492761] [PUBMED:22128142] [PUBMED:9122198] [PUBMED:8555464] [PUBMED:10397715] [PUBMED:11478766] [PUBMED:11356906] [PUBMED:18632638] [PUBMED:10720694] [PUBMED:17550780] [PUBMED:8943867] [PUBMED:12101178] [PUBMED:17389006] [PUBMED:9845531] [PUBMED:18773906] [PUBMED:10216087] [PUBMED:7537762] [PUBMED:15271793] [PUBMED:12389630] [PUBMED:8639892] [PUBMED:8202160] [PUBMED:15337790] [PUBMED:16449323] [PUBMED:22101255] [PUBMED:22628264] [PUBMED:17455223] [PUBMED:7796811] [PUBMED:18075837] [PUBMED:14693160] [PUBMED:14500680] [PUBMED:9012841] [PUBMED:6286773] [PUBMED:2830276] [PUBMED:9630621] [PUBMED:11097834] [PUBMED:9166841] [PUBMED:14726379] [PUBMED:9657746] [PUBMED:12006617] [PUBMED:19844195] [PUBMED:9028319] [PUBMED:7534285] [PUBMED:11012190] [PUBMED:11376875] [PUBMED:8950973] [PUBMED:10517496] [PUBMED:8541543] [PUBMED:10736563] [PUBMED:12372629] [PUBMED:19262695] [PUBMED:9600081] [PUBMED:16317100] [PUBMED:10891439] [PUBMED:17693582] [PUBMED:16150872] [PUBMED:6313047] [PUBMED:14645506] [PUBMED:15693793] [PUBMED:19620302]
CD28 co-stimulation [NCBI:1269178] [REACTOME:R-HSA-389356] [PUBMED:8649453] [PUBMED:8609386] [PUBMED:12165654]
CD28 dependent PI3K/Akt signaling [NCBI:1269179] [REACTOME:R-HSA-389357] [PUBMED:12670391] [PUBMED:15046602]
CDC42 signaling events [NCBI:137994] [Pathway Interaction Database:cdc42_pathway] [PUBMED:19454477] [PUBMED:7629060] [PUBMED:18662680] [PUBMED:15882626] [PUBMED:15225553] [PUBMED:7652575] [PUBMED:18448434] [PUBMED:11948177] [PUBMED:8107774] [PUBMED:9860974] [PUBMED:8670801] [PUBMED:8034624] [PUBMED:9822598] [PUBMED:17522712] [PUBMED:15723051] [PUBMED:10734320] [PUBMED:7600582] [PUBMED:10613909] [PUBMED:17580073] [PUBMED:11525734] [PUBMED:10840034] [PUBMED:12745076] [PUBMED:11907268] [PUBMED:18319301] [PUBMED:10473551] [PUBMED:9042860] [PUBMED:16157700] [PUBMED:10934475] [PUBMED:16253996] [PUBMED:10995437] [PUBMED:10360579] [PUBMED:9368021] [PUBMED:9403696] [PUBMED:11285260] [PUBMED:10219243] [PUBMED:9317150] [PUBMED:17081755] [PUBMED:17038317] [PUBMED:8702968] [PUBMED:10973943] [PUBMED:17115031] [PUBMED:14505571] [PUBMED:14970210] [PUBMED:14653992] [PUBMED:15485841] [PUBMED:12676083] [PUBMED:9694656] [PUBMED:17244649] [PUBMED:8625410] [PUBMED:7592586] [PUBMED:18216334] [PUBMED:19826000] [PUBMED:11304531] [PUBMED:16892055] [PUBMED:11696321] [PUBMED:19097998] [PUBMED:15479449] [PUBMED:16407834] [PUBMED:11309380] [PUBMED:9867866] [PUBMED:11804587] [PUBMED:10747870] [PUBMED:10559936] [PUBMED:8497321] [PUBMED:7600581] [PUBMED:12610628] [PUBMED:15572110] [PUBMED:19435802] [PUBMED:8653792] [PUBMED:19822663] [PUBMED:8643625] [PUBMED:10934474] [PUBMED:15649357] [PUBMED:8910292] [PUBMED:18586681]
CXCR3-mediated signaling events [NCBI:138011] [Pathway Interaction Database:cxcr3pathway] [PUBMED:15528361] [PUBMED:9541591] [PUBMED:16368892] [PUBMED:9660793] [PUBMED:18375741] [PUBMED:17289675] [PUBMED:16467404] [PUBMED:18291705] [PUBMED:15150261] [PUBMED:11554781] [PUBMED:9625760] [PUBMED:12750173] [PUBMED:18174362] [PUBMED:11739530] [PUBMED:12782716] [PUBMED:18292502] [PUBMED:11136732] [PUBMED:16210647]
CXCR4-mediated signaling events [NCBI:137910] [Pathway Interaction Database:cxcr4_pathway] [PUBMED:18799424] [PUBMED:10881171] [PUBMED:17675482] [PUBMED:17537990] [PUBMED:11157475] [PUBMED:12535795] [PUBMED:12077227] [PUBMED:11544290] [PUBMED:19380820] [PUBMED:8752280] [PUBMED:11784854] [PUBMED:12682230] [PUBMED:9722546] [PUBMED:16503409] [PUBMED:16230460] [PUBMED:15615703] [PUBMED:10606629] [PUBMED:17568820] [PUBMED:10521508] [PUBMED:11369622] [PUBMED:10753828] [PUBMED:10570282] [PUBMED:12590707] [PUBMED:15618472] [PUBMED:15994292] [PUBMED:16038794] [PUBMED:11641392] [PUBMED:12133960] [PUBMED:18596232] [PUBMED:14662753] [PUBMED:14602072] [PUBMED:12036857] [PUBMED:16919488] [PUBMED:18319399] [PUBMED:18227351] [PUBMED:10506573] [PUBMED:14704365] [PUBMED:15630457] [PUBMED:10952719] [PUBMED:10644702] [PUBMED:10491003] [PUBMED:12519755] [PUBMED:12032308] [PUBMED:8752281] [PUBMED:15728464] [PUBMED:15872091] [PUBMED:17056591]
Cellular response to heat stress [NCBI:1270421] [REACTOME:R-HSA-3371556] [PUBMED:8455624] [PUBMED:8441385]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Central carbon metabolism in cancer [NCBI:1059538] [KEGG:hsa05230] [PUBMED:16982728] [PUBMED:21127244] [PUBMED:22156302] [PUBMED:22349059] [PUBMED:21801601] [PUBMED:15916903] [PUBMED:24113830] [PUBMED:23018234] [PUBMED:22237205] [PUBMED:23897900] [PUBMED:20520704] [PUBMED:18177721] [PUBMED:24398961] [PUBMED:18538731] [PUBMED:24079832] [PUBMED:19460998] [PUBMED:22101401] [PUBMED:22750268] [PUBMED:22307140] [PUBMED:23071355] [PUBMED:21258394] [PUBMED:23279446] [PUBMED:21340684] [PUBMED:19270154] [PUBMED:18766298] [PUBMED:21508971] [PUBMED:24738035]
Choline metabolism in cancer [NCBI:1059539] [KEGG:hsa05231] [PUBMED:23350810] [PUBMED:16230400] [PUBMED:19264150] [PUBMED:22429397] [PUBMED:19136975] [PUBMED:22089420] [PUBMED:16432178] [PUBMED:14517341] [PUBMED:22921309] [PUBMED:19855431] [PUBMED:20528734] [PUBMED:19935796] [PUBMED:21793073] [PUBMED:14523987] [PUBMED:23076158]
Class I PI3K signaling events mediated by Akt [NCBI:138020] [Pathway Interaction Database:pi3kciaktpathway] [PUBMED:15718470] [PUBMED:10485710] [PUBMED:9812896] [PUBMED:10102273] [PUBMED:16919458] [PUBMED:16213228] [PUBMED:11154276] [PUBMED:12244301] [PUBMED:15057270] [PUBMED:16962653] [PUBMED:9346240] [PUBMED:17407381] [PUBMED:12637568] [PUBMED:8524413] [PUBMED:16982699] [PUBMED:18024423] [PUBMED:9637919] [PUBMED:10358075] [PUBMED:10576741] [PUBMED:11864996] [PUBMED:12244302] [PUBMED:11231573] [PUBMED:10949026] [PUBMED:15262962] [PUBMED:9094314] [PUBMED:9512493] [PUBMED:11777915] [PUBMED:12244303] [PUBMED:9381178] [PUBMED:10783894] [PUBMED:10217147]
Constitutive Signaling by AKT1 E17K in Cancer [NCBI:1268881] [REACTOME:R-HSA-5674400] [PUBMED:17611497] [PUBMED:18954143]
Costimulation by the CD28 family [NCBI:1269177] [REACTOME:R-HSA-388841] [PUBMED:10374692] [PUBMED:11905831] [PUBMED:14647476]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
Downstream signaling events of B Cell Receptor (BCR) [NCBI:1269185] [REACTOME:R-HSA-1168372] [PUBMED:17052215] [PUBMED:19909372]
Downstream signaling of activated FGFR1 [NCBI:1269392] [REACTOME:R-HSA-5654687] [PUBMED:8752212]
Downstream signaling of activated FGFR2 [NCBI:1269403] [REACTOME:R-HSA-5654696] [PUBMED:8752212]
Downstream signaling of activated FGFR3 [NCBI:1269413] [REACTOME:R-HSA-5654708] [PUBMED:8752212]
Downstream signaling of activated FGFR4 [NCBI:1269422] [REACTOME:R-HSA-5654716] [PUBMED:8752212]
EGFR-dependent Endothelin signaling events [NCBI:138037] [Pathway Interaction Database:et_egfrpathway] [PUBMED:16261333] [PUBMED:10499523] [PUBMED:9595433] [PUBMED:16391241] [PUBMED:8596637]
Energy dependent regulation of mTOR by LKB1-AMPK [NCBI:1269439] [REACTOME:R-HSA-380972] [PUBMED:17613433] [PUBMED:17712357] [PUBMED:17010524]
ErbB signaling pathway [NCBI:83049] [KEGG:hsa04012] [NCBI:198844] [WikiPathways:WP673] [PUBMED:14967450] [PUBMED:16377102] [PUBMED:10880430] [PUBMED:9872057] [PUBMED:9642287] [PUBMED:12851486] [PUBMED:20573930] [PUBMED:16729045] [PUBMED:15863494] [PUBMED:16829981] [PUBMED:14744244] [PUBMED:10490623] [PUBMED:15864276] [PUBMED:17000658] [PUBMED:11252954] [PUBMED:16729043]
ErbB1 downstream signaling [NCBI:138057] [Pathway Interaction Database:erbb1_downstream_pathway] [PUBMED:1330321] [PUBMED:9448004] [PUBMED:17563371] [PUBMED:3497813] [PUBMED:8073291] [PUBMED:7939666] [PUBMED:12503606] [PUBMED:1990291] [PUBMED:15550174] [PUBMED:17881733] [PUBMED:9889102] [PUBMED:11278353] [PUBMED:8378775] [PUBMED:9580112] [PUBMED:7680434] [PUBMED:11018520] [PUBMED:19219045] [PUBMED:10499589] [PUBMED:18567582] [PUBMED:12183455] [PUBMED:9315636] [PUBMED:9733714] [PUBMED:10567369] [PUBMED:2189103] [PUBMED:14699061] [PUBMED:8262053] [PUBMED:8248196] [PUBMED:12932319] [PUBMED:11319218] [PUBMED:19541618] [PUBMED:19595761] [PUBMED:15048123] [PUBMED:19341767] [PUBMED:9837959] [PUBMED:19706684] [PUBMED:8910287] [PUBMED:11073940] [PUBMED:14993287] [PUBMED:18516090] [PUBMED:11029289] [PUBMED:8052307] [PUBMED:2123453] [PUBMED:8140422] [PUBMED:8071311] [PUBMED:10644690] [PUBMED:9384584] [PUBMED:16239230] [PUBMED:8397445] [PUBMED:8332195] [PUBMED:8621729] [PUBMED:9989263] [PUBMED:12172553] [PUBMED:7637810] [PUBMED:11152283] [PUBMED:11889038] [PUBMED:10648629] [PUBMED:18156174] [PUBMED:8013650] [PUBMED:12446727] [PUBMED:8688081] [PUBMED:16135787] [PUBMED:7600581] [PUBMED:9438848] [PUBMED:12881422] [PUBMED:10082559] [PUBMED:15718470] [PUBMED:9407138] [PUBMED:8248197] [PUBMED:12515821] [PUBMED:7741752] [PUBMED:8413226] [PUBMED:9790194] [PUBMED:9305638] [PUBMED:15284024] [PUBMED:9797479] [PUBMED:16093354] [PUBMED:3136398] [PUBMED:10597268] [PUBMED:17079732] [PUBMED:9550702] [PUBMED:12414794] [PUBMED:9710644] [PUBMED:12110590] [PUBMED:12181570] [PUBMED:17322878] [PUBMED:16628218] [PUBMED:16892053] [PUBMED:12640115] [PUBMED:8221888] [PUBMED:9927426] [PUBMED:17052213] [PUBMED:1653949] [PUBMED:10400627] [PUBMED:12242303] [PUBMED:15039778] [PUBMED:10567531] [PUBMED:14609431] [PUBMED:9346240] [PUBMED:1406636] [PUBMED:11948693] [PUBMED:9665134] [PUBMED:8503013] [PUBMED:9770464] [PUBMED:7761091] [PUBMED:17486115] [PUBMED:14690430] [PUBMED:9430728] [PUBMED:11238956] [PUBMED:19401591] [PUBMED:16155590] [PUBMED:10480933] [PUBMED:8378774] [PUBMED:8942998] [PUBMED:7600582] [PUBMED:1545823] [PUBMED:12454019] [PUBMED:7992057] [PUBMED:11777939] [PUBMED:18775988] [PUBMED:8940018] [PUBMED:10675331] [PUBMED:7958858] [PUBMED:16407412] [PUBMED:8621573] [PUBMED:2109185] [PUBMED:10441128] [PUBMED:14747473] [PUBMED:19121340] [PUBMED:11134016] [PUBMED:7889942] [PUBMED:8180183] [PUBMED:14498832] [PUBMED:12429840] [PUBMED:8226933] [PUBMED:8386592] [PUBMED:15034142] [PUBMED:6334806] [PUBMED:7876145] [PUBMED:10201527] [PUBMED:11703925] [PUBMED:11099046] [PUBMED:12832467] [PUBMED:9596579] [PUBMED:16508002] [PUBMED:9335504] [PUBMED:17360704] [PUBMED:10469645] [PUBMED:19710016] [PUBMED:14765121] [PUBMED:14970219] [PUBMED:12551925] [PUBMED:10856237] [PUBMED:9593664] [PUBMED:10891480] [PUBMED:16984645] [PUBMED:14963038] [PUBMED:17053785] [PUBMED:8614832] [PUBMED:8626780] [PUBMED:1637333] [PUBMED:3492494] [PUBMED:8524316] [PUBMED:7731720]
ErbB2/ErbB3 signaling events [NCBI:137955] [Pathway Interaction Database:erbb2erbb3pathway] [PUBMED:9677338] [PUBMED:11546794] [PUBMED:11984589] [PUBMED:19474313] [PUBMED:18614687] [PUBMED:12072561] [PUBMED:9710588] [PUBMED:18760695] [PUBMED:11027222] [PUBMED:12466964] [PUBMED:7556067] [PUBMED:19535578] [PUBMED:12411582] [PUBMED:17210635] [PUBMED:15520002] [PUBMED:10531446] [PUBMED:17998937] [PUBMED:8815893] [PUBMED:18799465] [PUBMED:12651161] [PUBMED:19019207] [PUBMED:10101228] [PUBMED:18426980] [PUBMED:11173924] [PUBMED:19179536] [PUBMED:9362461] [PUBMED:10399934] [PUBMED:7877996] [PUBMED:11940572] [PUBMED:11312610] [PUBMED:9338783] [PUBMED:8707830] [PUBMED:11564761] [PUBMED:9694850] [PUBMED:9637684] [PUBMED:10582594] [PUBMED:8702681] [PUBMED:10704452] [PUBMED:10493750] [PUBMED:16481445] [PUBMED:9049301]
FSH signaling pathway [NCBI:672455] [WikiPathways:WP2035]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:21799019] [PUBMED:15099567]
GAB1 signalosome [NCBI:1269384] [REACTOME:R-HSA-180292] [PUBMED:15550174]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15680972] [PUBMED:14744435] [PUBMED:15175151] [PUBMED:15896744] [PUBMED:11395415] [PUBMED:10235266] [PUBMED:12023297] [PUBMED:14986688] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:16719718] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:15690163] [PUBMED:16921404]
Glioma [NCBI:83110] [KEGG:hsa05214] [PUBMED:11253051] [PUBMED:12154354] [PUBMED:11057895] [PUBMED:12084351] [PUBMED:15639402] [PUBMED:9643506] [PUBMED:16095998] [PUBMED:12762887] [PUBMED:16700615]
HIF-1 signaling pathway [NCBI:695200] [KEGG:hsa04066] [PUBMED:11902584] [PUBMED:22205687] [PUBMED:15031665] [PUBMED:19364912] [PUBMED:18259201] [PUBMED:18505681] [PUBMED:15448722] [PUBMED:19147540] [PUBMED:20836033] [PUBMED:19861159] [PUBMED:22562152] [PUBMED:20965423] [PUBMED:20679415] [PUBMED:16234508] [PUBMED:17955264]
HSF1-dependent transactivation [NCBI:1270423] [REACTOME:R-HSA-3371571] [PUBMED:7623826]
IFN-gamma pathway [NCBI:138040] [Pathway Interaction Database:ifngpathway] [PUBMED:11909529] [PUBMED:9724754] [PUBMED:10067896] [PUBMED:15878863] [PUBMED:9271410] [PUBMED:7514165] [PUBMED:11171987] [PUBMED:11438544] [PUBMED:8608598] [PUBMED:11971965] [PUBMED:12817007] [PUBMED:8232552] [PUBMED:15051500] [PUBMED:17032168] [PUBMED:8156998] [PUBMED:10485906] [PUBMED:8755534] [PUBMED:10490100] [PUBMED:7510216] [PUBMED:11972023] [PUBMED:12270932] [PUBMED:15311277] [PUBMED:8986769] [PUBMED:12438563] [PUBMED:10022928] [PUBMED:12048245] [PUBMED:14670297] [PUBMED:12138178] [PUBMED:7690989] [PUBMED:12050152] [PUBMED:9336467] [PUBMED:8608597] [PUBMED:10805787] [PUBMED:1281555] [PUBMED:15879117] [PUBMED:7777519] [PUBMED:12855578] [PUBMED:10995751] [PUBMED:10490099] [PUBMED:10657627] [PUBMED:10777554] [PUBMED:17606919]
IGF1R signaling cascade [NCBI:1269618] [REACTOME:R-HSA-2428924] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959]
IL12-mediated signaling events [NCBI:137922] [Pathway Interaction Database:il12_2pathway] [PUBMED:12874225] [PUBMED:12221108] [PUBMED:16380506] [PUBMED:9768751] [PUBMED:17114419] [PUBMED:9202126] [PUBMED:16641133] [PUBMED:10198225] [PUBMED:9890938] [PUBMED:16763563] [PUBMED:15728489] [PUBMED:12213961] [PUBMED:8103068] [PUBMED:11894097] [PUBMED:10201984] [PUBMED:10961885] [PUBMED:7638186] [PUBMED:9582275] [PUBMED:7594594] [PUBMED:16220539] [PUBMED:17110450] [PUBMED:7528775] [PUBMED:9531298] [PUBMED:11175814] [PUBMED:10320373] [PUBMED:15522880] [PUBMED:11207258] [PUBMED:8943050] [PUBMED:7722452] [PUBMED:7553885] [PUBMED:9454765] [PUBMED:10358173] [PUBMED:11120802] [PUBMED:10903740] [PUBMED:9038232]
IL2 signaling events mediated by PI3K [NCBI:137938] [Pathway Interaction Database:il2_pi3kpathway] [PUBMED:7543780] [PUBMED:15271800] [PUBMED:9162082] [PUBMED:8617294] [PUBMED:9092570] [PUBMED:7737351] [PUBMED:9108028] [PUBMED:11486019] [PUBMED:1614535] [PUBMED:9771966] [PUBMED:7760801] [PUBMED:15843522] [PUBMED:12393431] [PUBMED:1652056] [PUBMED:3523754] [PUBMED:10373522] [PUBMED:12525482] [PUBMED:7736574] [PUBMED:10982827] [PUBMED:7589144] [PUBMED:7528328] [PUBMED:9029085] [PUBMED:11994454]
IL4-mediated signaling events [NCBI:137933] [Pathway Interaction Database:il4_2pathway] [PUBMED:8624802] [PUBMED:8602263] [PUBMED:15199062] [PUBMED:7705411] [PUBMED:8557643] [PUBMED:1948049] [PUBMED:11160325] [PUBMED:11034397] [PUBMED:14557412] [PUBMED:8134361] [PUBMED:10843732] [PUBMED:10586089] [PUBMED:1997653] [PUBMED:10228008] [PUBMED:14634100] [PUBMED:12574343] [PUBMED:17541284] [PUBMED:16210622] [PUBMED:7822337] [PUBMED:2147202] [PUBMED:15659391] [PUBMED:7675087] [PUBMED:7760829] [PUBMED:7973658] [PUBMED:12459556] [PUBMED:10490661] [PUBMED:8624803] [PUBMED:11160269] [PUBMED:14603527] [PUBMED:9811885] [PUBMED:12776189] [PUBMED:9013879] [PUBMED:10601358] [PUBMED:8266078] [PUBMED:11739727] [PUBMED:15728454] [PUBMED:8992992] [PUBMED:8609418] [PUBMED:15004182] [PUBMED:11160275] [PUBMED:9110977] [PUBMED:11241672] [PUBMED:9852037] [PUBMED:10201892] [PUBMED:17200144] [PUBMED:10950967] [PUBMED:8624821] [PUBMED:8916957] [PUBMED:16810739] [PUBMED:7499365] [PUBMED:15187136] [PUBMED:11801631] [PUBMED:7721786] [PUBMED:9414268] [PUBMED:12044779] [PUBMED:10657944] [PUBMED:12242343] [PUBMED:7544011] [PUBMED:11544308] [PUBMED:8621475] [PUBMED:8458387] [PUBMED:8266076] [PUBMED:15153491] [PUBMED:8085155] [PUBMED:9380721] [PUBMED:9799097] [PUBMED:8258319] [PUBMED:12023955] [PUBMED:9697832] [PUBMED:9541585] [PUBMED:7807002] [PUBMED:7694370] [PUBMED:16537510] [PUBMED:8124718] [PUBMED:11572871] [PUBMED:14978013] [PUBMED:10364072] [PUBMED:11714803] [PUBMED:8602264] [PUBMED:10072514] [PUBMED:3144043] [PUBMED:8089482] [PUBMED:9651359] [PUBMED:9670964] [PUBMED:9065461] [PUBMED:8810328]
IRS-mediated signalling [NCBI:1269431] [REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R [NCBI:1269620] [REACTOME:R-HSA-2428928] [PUBMED:20975071] [PUBMED:17598937] [PUBMED:22649417] [PUBMED:18927274] [PUBMED:21042815] [PUBMED:20098959]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Insulin Signaling [NCBI:198845] [WikiPathways:WP481] [PUBMED:11742412] [PUBMED:1890850] [PUBMED:11282018]
Insulin receptor signalling cascade [NCBI:1269429] [REACTOME:R-HSA-74751] [PUBMED:9677303] [PUBMED:11282018]
Insulin resistance [NCBI:1272486] [KEGG:hsa04931] [PUBMED:20466550] [PUBMED:17130651] [PUBMED:16364488] [PUBMED:12765939] [PUBMED:15166380] [PUBMED:7666792] [PUBMED:10923637] [PUBMED:23647930] [PUBMED:16756496] [PUBMED:17141630] [PUBMED:18309108] [PUBMED:20526383] [PUBMED:22675355] [PUBMED:16186396] [PUBMED:15107844] [PUBMED:22360800] [PUBMED:9886945] [PUBMED:8048519] [PUBMED:22677645]
Insulin signaling pathway [NCBI:83090] [KEGG:hsa04910] [PUBMED:15733744] [PUBMED:11282018] [PUBMED:10196204] [PUBMED:18291668] [PUBMED:9609110] [PUBMED:15624019] [PUBMED:9346240] [PUBMED:9445476] [PUBMED:12791379] [PUBMED:9748166] [PUBMED:14635525] [PUBMED:15229476] [PUBMED:12867054] [PUBMED:17344645] [PUBMED:9609111] [PUBMED:11343120] [PUBMED:11742412] [PUBMED:10567225] [PUBMED:16288289]
Integrated Breast Cancer Pathway [NCBI:219801] [WikiPathways:WP1984] [PUBMED:16438734] [PUBMED:7859292] [PUBMED:2147360] [PUBMED:16087680] [PUBMED:11003670] [PUBMED:8182145] [PUBMED:16601937] [PUBMED:17623674] [PUBMED:12221076] [PUBMED:10363963] [PUBMED:11356332] [PUBMED:10880455] [PUBMED:16597033] [PUBMED:8758926] [PUBMED:1199706] [PUBMED:9688941] [PUBMED:2828745] [PUBMED:15701627] [PUBMED:7966593] [PUBMED:10022864]
Interferon type I [NCBI:920993] [WikiPathways:WP585] [PUBMED:2153461] [PUBMED:10514501] [PUBMED:7665574] [PUBMED:8524272] [PUBMED:10644731] [PUBMED:1468582] [PUBMED:9287210] [PUBMED:8496154] [PUBMED:8232552] [PUBMED:9724754] [PUBMED:8550573] [PUBMED:10428508] [PUBMED:17604604] [PUBMED:9857039] [PUBMED:8181059] [PUBMED:8780698] [PUBMED:7608146] [PUBMED:1496401] [PUBMED:1280824] [PUBMED:1638633] [PUBMED:9305869] [PUBMED:7988557] [PUBMED:9295335] [PUBMED:8628273] [PUBMED:10022928] [PUBMED:9196040] [PUBMED:9374471] [PUBMED:9872990] [PUBMED:9326223]
Jak-STAT signaling pathway [NCBI:83077] [KEGG:hsa04630] [PUBMED:21034406] [PUBMED:22339650] [PUBMED:25587654] [PUBMED:24606160] [PUBMED:24069565] [PUBMED:22383755] [PUBMED:23735217] [PUBMED:10851053] [PUBMED:25217450] [PUBMED:16204702] [PUBMED:21372217]
LKB1 signaling events [NCBI:137957] [Pathway Interaction Database:lkb1_pathway] [PUBMED:12429843] [PUBMED:16912160] [PUBMED:18339622] [PUBMED:19513107] [PUBMED:16959574] [PUBMED:14614828] [PUBMED:11741830] [PUBMED:7706316] [PUBMED:18063805] [PUBMED:12805220] [PUBMED:16306228] [PUBMED:19386264] [PUBMED:18439900] [PUBMED:12489981] [PUBMED:17959818] [PUBMED:16396636] [PUBMED:19622832] [PUBMED:15016379] [PUBMED:17991864] [PUBMED:16308421] [PUBMED:11445556] [PUBMED:17482548] [PUBMED:14676191] [PUBMED:14517248] [PUBMED:14511394] [PUBMED:15261145] [PUBMED:9108484] [PUBMED:19369417] [PUBMED:16817901] [PUBMED:10642527] [PUBMED:14985505] [PUBMED:17573348] [PUBMED:16627617] [PUBMED:12973359] [PUBMED:14976552] [PUBMED:8631898] [PUBMED:17482549] [PUBMED:15454081] [PUBMED:10542369] [PUBMED:14651849] [PUBMED:15705853]
Leptin signaling pathway [NCBI:672456] [WikiPathways:WP2034]
Longevity regulating pathway [NCBI:1319989] [KEGG:hsa04211] [PUBMED:21779512] [PUBMED:23594965] [PUBMED:25832544] [PUBMED:25654554] [PUBMED:24997879] [PUBMED:22618766] [PUBMED:20336132] [PUBMED:25601466] [PUBMED:24905167] [PUBMED:18692468] [PUBMED:20395504] [PUBMED:23939249] [PUBMED:17701476] [PUBMED:25824609] [PUBMED:20848587] [PUBMED:20357764] [PUBMED:19262508] [PUBMED:22983298] [PUBMED:23061800] [PUBMED:18946478] [PUBMED:20103737]
Longevity regulating pathway - multiple species [NCBI:1340713] [KEGG:hsa04213] [PUBMED:26682004] [PUBMED:20098959] [PUBMED:17684529] [PUBMED:16304601] [PUBMED:17701476] [PUBMED:14534077] [PUBMED:18373439] [PUBMED:20395504] [PUBMED:22094419] [PUBMED:26525455] [PUBMED:20336132] [PUBMED:21909281] [PUBMED:23615258] [PUBMED:21841070] [PUBMED:15768047] [PUBMED:18946478] [PUBMED:20097433] [PUBMED:12610293] [PUBMED:25153840]
Macroautophagy [NCBI:1270432] [REACTOME:R-HSA-1632852] [PUBMED:24296784]
MicroRNAs in cancer [NCBI:852705] [KEGG:hsa05206] [PUBMED:23075324] [PUBMED:22351564] [PUBMED:21742789] [PUBMED:21402473] [PUBMED:21565290] [PUBMED:23091478] [PUBMED:23316212] [PUBMED:19630570] [PUBMED:19773200] [PUBMED:23462054] [PUBMED:20345848] [PUBMED:22035854] [PUBMED:20221895] [PUBMED:22580099] [PUBMED:20128019] [PUBMED:18817506] [PUBMED:22345301] [PUBMED:22926415] [PUBMED:23165235]
MicroRNAs in cardiomyocyte hypertrophy [NCBI:198784] [WikiPathways:WP1544] [PUBMED:10615383] [PUBMED:10189350] [PUBMED:9253712] [PUBMED:9488659] [PUBMED:10827130] [PUBMED:11055975] [PUBMED:9568714] [PUBMED:19018142] [PUBMED:20407820] [PUBMED:11101507] [PUBMED:10864911] [PUBMED:10698680] [PUBMED:16936699] [PUBMED:17468766] [PUBMED:18342376] [PUBMED:8621626] [PUBMED:10086361]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Oncostatin M Signaling Pathway [NCBI:711361] [WikiPathways:WP2374] [PUBMED:9600081] [PUBMED:6313047] [PUBMED:16150872] [PUBMED:22528490] [PUBMED:16317100] [PUBMED:9731041] [PUBMED:17637498] [PUBMED:21325822] [PUBMED:10050883] [PUBMED:17693582] [PUBMED:17925492] [PUBMED:20113333] [PUBMED:7537762] [PUBMED:6325330] [PUBMED:17389006] [PUBMED:11012189] [PUBMED:15693793] [PUBMED:7492761] [PUBMED:10397715] [PUBMED:17550780] [PUBMED:10720694] [PUBMED:22005786] [PUBMED:17455223] [PUBMED:17980909] [PUBMED:14576068] [PUBMED:11309383] [PUBMED:8555464] [PUBMED:18487512] [PUBMED:2830276] [PUBMED:18632638] [PUBMED:18773906] [PUBMED:9122198] [PUBMED:8943867] [PUBMED:9845531] [PUBMED:9630621] [PUBMED:11097834] [PUBMED:15271793] [PUBMED:8639892] [PUBMED:12389630] [PUBMED:12101178] [PUBMED:7796811] [PUBMED:16449323] [PUBMED:18075837] [PUBMED:19620302] [PUBMED:22101255] [PUBMED:11478766] [PUBMED:22628264] [PUBMED:22128142] [PUBMED:14500680] [PUBMED:19261614] [PUBMED:9012841] [PUBMED:12036856] [PUBMED:9166841] [PUBMED:12006617] [PUBMED:10224114] [PUBMED:16123382] [PUBMED:11012190] [PUBMED:9373250] [PUBMED:11204567] [PUBMED:15504554] [PUBMED:12855555] [PUBMED:11085749] [PUBMED:19844195] [PUBMED:15337790] [PUBMED:11054408] [PUBMED:10979953] [PUBMED:20870899] [PUBMED:8760293] [PUBMED:11922610] [PUBMED:14693160] [PUBMED:9070265] [PUBMED:7780132] [PUBMED:18256550] [PUBMED:11376875] [PUBMED:10651727] [PUBMED:9711904] [PUBMED:10611229] [PUBMED:22809535] [PUBMED:10918061] [PUBMED:11750880] [PUBMED:9506832] [PUBMED:18804163] [PUBMED:18528423] [PUBMED:10419886] [PUBMED:18422784] [PUBMED:14687665] [PUBMED:17658515] [PUBMED:21898686] [PUBMED:9990315] [PUBMED:7589510] [PUBMED:16368886] [PUBMED:15673499] [PUBMED:21304100] [PUBMED:10438715] [PUBMED:9257862] [PUBMED:9028319] [PUBMED:9305885] [PUBMED:21490406] [PUBMED:15001470] [PUBMED:9396763] [PUBMED:19289146] [PUBMED:11402314] [PUBMED:20576130] [PUBMED:19888469] [PUBMED:21892137] [PUBMED:9654143] [PUBMED:11429396] [PUBMED:21900501] [PUBMED:8877093] [PUBMED:8695851] [PUBMED:15863506] [PUBMED:22456226] [PUBMED:22514603] [PUBMED:8950973] [PUBMED:10460590] [PUBMED:15778351] [PUBMED:15701720] [PUBMED:11238104] [PUBMED:15705785] [PUBMED:16249382] [PUBMED:19038790] [PUBMED:11278373] [PUBMED:9632812] [PUBMED:14576181] [PUBMED:9120001] [PUBMED:11861812] [PUBMED:18618018] [PUBMED:10517496] [PUBMED:7795229] [PUBMED:7545904] [PUBMED:11376873] [PUBMED:20838657] [PUBMED:8843545] [PUBMED:12495897] [PUBMED:9119889] [PUBMED:16418722] [PUBMED:11446731] [PUBMED:18796624] [PUBMED:10090948] [PUBMED:11110685] [PUBMED:9002950] [PUBMED:20976181] [PUBMED:11266445] [PUBMED:19631713] [PUBMED:17284614] [PUBMED:9446641] [PUBMED:11567993] [PUBMED:11756417] [PUBMED:8632906] [PUBMED:17244674] [PUBMED:15271795] [PUBMED:19619605] [PUBMED:19714753] [PUBMED:22649382] [PUBMED:11418622] [PUBMED:19996410] [PUBMED:20335227] [PUBMED:10803464] [PUBMED:10891439] [PUBMED:15642952] [PUBMED:20586925] [PUBMED:7488109] [PUBMED:17021950] [PUBMED:21630326] [PUBMED:16115772] [PUBMED:10321988] [PUBMED:12145691] [PUBMED:17827152] [PUBMED:8628315] [PUBMED:11830463] [PUBMED:15671147] [PUBMED:11535599] [PUBMED:18456388] [PUBMED:9108397] [PUBMED:9679986] [PUBMED:10681535] [PUBMED:10194437] [PUBMED:14617636] [PUBMED:10515871] [PUBMED:8541543] [PUBMED:10736563] [PUBMED:12032335] [PUBMED:18288130] [PUBMED:9663467] [PUBMED:11964286] [PUBMED:11934880] [PUBMED:9108383] [PUBMED:15085152] [PUBMED:21527831] [PUBMED:11283246] [PUBMED:6286773] [PUBMED:17525997] [PUBMED:10216087] [PUBMED:14662334] [PUBMED:8202160] [PUBMED:21933853] [PUBMED:11356906] [PUBMED:14726379] [PUBMED:9657746] [PUBMED:14645506] [PUBMED:8695859] [PUBMED:11722433] [PUBMED:10415383] [PUBMED:11980901] [PUBMED:15588513] [PUBMED:19744539] [PUBMED:7534285] [PUBMED:11784712] [PUBMED:10477685] [PUBMED:18060035] [PUBMED:9111365] [PUBMED:11389697] [PUBMED:9475764] [PUBMED:21853157] [PUBMED:10205146] [PUBMED:8549784] [PUBMED:12372629] [PUBMED:10361118] [PUBMED:11500082] [PUBMED:7649975] [PUBMED:19262695] [PUBMED:20502002] [PUBMED:12359731]
PI-3K cascade:FGFR1 [NCBI:1269396] [REACTOME:R-HSA-5654689] [PUBMED:11057895] [PUBMED:12089343] [PUBMED:12558974] [PUBMED:10918587] [PUBMED:15863030]
PI-3K cascade:FGFR2 [NCBI:1269407] [REACTOME:R-HSA-5654695] [PUBMED:15863030] [PUBMED:11057895] [PUBMED:12558974] [PUBMED:12089343] [PUBMED:10918587]
PI-3K cascade:FGFR3 [NCBI:1269417] [REACTOME:R-HSA-5654710] [PUBMED:10918587] [PUBMED:15863030] [PUBMED:11057895] [PUBMED:12558974] [PUBMED:12089343]
PI-3K cascade:FGFR4 [NCBI:1269426] [REACTOME:R-HSA-5654720] [PUBMED:15863030] [PUBMED:10918587] [PUBMED:11057895] [PUBMED:12558974] [PUBMED:12089343]
PI3K Cascade [NCBI:1269432] [REACTOME:R-HSA-109704]
PI3K events in ERBB4 signaling [NCBI:1269498] [REACTOME:R-HSA-1250342]
PI3K-Akt signaling pathway [NCBI:692234] [KEGG:hsa04151] [PUBMED:11357143] [PUBMED:12048182] [PUBMED:12669022] [PUBMED:15209374] [PUBMED:18842113] [PUBMED:16847462] [PUBMED:12660731] [PUBMED:15505410] [PUBMED:21779440] [PUBMED:12531180] [PUBMED:21620960] [PUBMED:16187290] [PUBMED:15784165] [PUBMED:21440011] [PUBMED:17360849] [PUBMED:16248975] [PUBMED:9838078]
PI3K/AKT Signaling in Cancer [NCBI:1268879] [REACTOME:R-HSA-2219528] [PUBMED:19644473] [PUBMED:20713702] [PUBMED:10555148] [PUBMED:21478295] [PUBMED:17626883] [PUBMED:17611497] [PUBMED:18317450] [PUBMED:18079394] [PUBMED:16339315] [PUBMED:19962665] [PUBMED:9326929] [PUBMED:20009532] [PUBMED:17604717] [PUBMED:9467011] [PUBMED:18954143] [PUBMED:21430697] [PUBMED:10866302] [PUBMED:19487573]
PI3K/AKT activation [NCBI:1269473] [REACTOME:R-HSA-198203] [PUBMED:10579926] [PUBMED:12123609]
PIP3 activates AKT signaling [NCBI:1269188] [REACTOME:R-HSA-1257604]
PKB-mediated events [NCBI:1269434] [REACTOME:R-HSA-109703]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:16001072] [PUBMED:16699851] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:15156182] [PUBMED:15310786] [PUBMED:21193867] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:12951584] [PUBMED:11071626] [PUBMED:9834202] [PUBMED:15721476] [PUBMED:11895903] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:11477132] [PUBMED:15724144] [PUBMED:10647931] [PUBMED:16700615] [PUBMED:11527574] [PUBMED:16339096] [PUBMED:12545153] [PUBMED:15942304] [PUBMED:16352814] [PUBMED:15656799] [PUBMED:10740269] [PUBMED:16881963] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:17287871] [PUBMED:15557758] [PUBMED:10944551] [PUBMED:11170304] [PUBMED:12154354] [PUBMED:15639402] [PUBMED:16326109] [PUBMED:11276000] [PUBMED:15573119] [PUBMED:15625120] [PUBMED:15109562] [PUBMED:11160144] [PUBMED:15611513] [PUBMED:15349822] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:16551846] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:11130178] [PUBMED:14580692] [PUBMED:14634372] [PUBMED:12407699] [PUBMED:12588368] [PUBMED:15009714] [PUBMED:16001050] [PUBMED:16112428] [PUBMED:9643506] [PUBMED:15468170] [PUBMED:16248975] [PUBMED:12946833] [PUBMED:11057895] [PUBMED:11559746] [PUBMED:16306523] [PUBMED:16064138] [PUBMED:15479695] [PUBMED:11900250] [PUBMED:9422516] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:12894244] [PUBMED:11103787] [PUBMED:12878745] [PUBMED:16702400] [PUBMED:14685170] [PUBMED:16189154] [PUBMED:11720739] [PUBMED:15122209] [PUBMED:11078609] [PUBMED:12243753] [PUBMED:14982876] [PUBMED:16642045] [PUBMED:12563308] [PUBMED:11407945] [PUBMED:14586404] [PUBMED:15270885] [PUBMED:16095998] [PUBMED:15948971] [PUBMED:16484590] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11459867] [PUBMED:10505543] [PUBMED:15746962] [PUBMED:16146838] [PUBMED:15947972] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:15841168] [PUBMED:11463388] [PUBMED:16474624] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:14556242] [PUBMED:10453277] [PUBMED:11721960] [PUBMED:11905738] [PUBMED:10403855] [PUBMED:12741677] [PUBMED:12616528] [PUBMED:15823750] [PUBMED:12737309] [PUBMED:14695152] [PUBMED:16750612] [PUBMED:11807782] [PUBMED:12351585] [PUBMED:14737121] [PUBMED:12801837] [PUBMED:11431710] [PUBMED:11165748] [PUBMED:11750244] [PUBMED:11224709] [PUBMED:16110317] [PUBMED:16508724] [PUBMED:15948711] [PUBMED:16870043] [PUBMED:7585656] [PUBMED:12379883] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:14747944] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:17158541] [PUBMED:12468433] [PUBMED:16042571] [PUBMED:16557281] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:16189702] [PUBMED:8069858] [PUBMED:12951588] [PUBMED:16242838] [PUBMED:15082523] [PUBMED:17211469] [PUBMED:12711111] [PUBMED:15284264] [PUBMED:11223406] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:16946003] [PUBMED:12762887] [PUBMED:16054233] [PUBMED:16822996] [PUBMED:17554387] [PUBMED:17028294]
Phospholipase D signaling pathway [NCBI:1311074] [KEGG:hsa04072] [PUBMED:9119890] [PUBMED:9310372] [PUBMED:18936782] [PUBMED:24990952] [PUBMED:14769825] [PUBMED:21936578] [PUBMED:10666319] [PUBMED:17210675] [PUBMED:23076158] [PUBMED:16622417] [PUBMED:11042115] [PUBMED:19264150] [PUBMED:17054901] [PUBMED:12217395] [PUBMED:19815110] [PUBMED:17245604] [PUBMED:10807766] [PUBMED:24995811] [PUBMED:11991733] [PUBMED:8135758] [PUBMED:19410013] [PUBMED:15310762] [PUBMED:16143829]
Prolactin Signaling Pathway [NCBI:672462] [WikiPathways:WP2037]
Prostate Cancer [NCBI:755440] [WikiPathways:WP2263] [PUBMED:18538735]
Prostate cancer [NCBI:83111] [KEGG:hsa05215] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11750244] [PUBMED:16551847] [PUBMED:10835690] [PUBMED:8069858] [PUBMED:15724144] [PUBMED:10453277] [PUBMED:15082523] [PUBMED:9422516] [PUBMED:11527574]
Proteoglycans in cancer [NCBI:782000] [KEGG:hsa05205] [PUBMED:19433454] [PUBMED:18798267] [PUBMED:20655987] [PUBMED:10633082] [PUBMED:22735579] [PUBMED:9346940] [PUBMED:22194599] [PUBMED:10687947] [PUBMED:24412155] [PUBMED:22087031] [PUBMED:15655247] [PUBMED:17971838] [PUBMED:14711376] [PUBMED:23058688] [PUBMED:18450475] [PUBMED:11830493] [PUBMED:12748184] [PUBMED:18413366] [PUBMED:20974860] [PUBMED:19733083] [PUBMED:18812315] [PUBMED:11931647] [PUBMED:12729888] [PUBMED:23305321] [PUBMED:12509413] [PUBMED:15994311] [PUBMED:18949819] [PUBMED:22563565] [PUBMED:22033227] [PUBMED:18505598] [PUBMED:11717317] [PUBMED:19255147] [PUBMED:21155971]
RANKL/RANK Signaling Pathway [NCBI:672447] [WikiPathways:WP2018]
Regulation of TP53 Activity [NCBI:1383076] [REACTOME:R-HSA-5633007] [PUBMED:20457558] [PUBMED:23825024] [PUBMED:25641576] [PUBMED:19450511]
Regulation of TP53 Degradation [NCBI:1383079] [REACTOME:R-HSA-6804757] [PUBMED:10570149] [PUBMED:11883935] [PUBMED:15563468] [PUBMED:21730132] [PUBMED:16845383] [PUBMED:11923872] [PUBMED:17290220] [PUBMED:17121812] [PUBMED:21730163] [PUBMED:10673500] [PUBMED:9843217] [PUBMED:19838211] [PUBMED:16163388] [PUBMED:10722742] [PUBMED:10608892] [PUBMED:9733514] [PUBMED:19450511] [PUBMED:11359766] [PUBMED:21986495] [PUBMED:19816404] [PUBMED:11983168] [PUBMED:11504915] [PUBMED:8319905] [PUBMED:19756449] [PUBMED:9733515] [PUBMED:20438709] [PUBMED:9529249] [PUBMED:11715018] [PUBMED:16474402] [PUBMED:15788536]
Regulation of TP53 Expression and Degradation [NCBI:1383077] [REACTOME:R-HSA-6806003] [PUBMED:11883935] [PUBMED:11923872] [PUBMED:19293287] [PUBMED:17499002] [PUBMED:15563468] [PUBMED:15103385] [PUBMED:17121812] [PUBMED:21814038] [PUBMED:21986495] [PUBMED:7878469] [PUBMED:19250907] [PUBMED:16213212] [PUBMED:23303139] [PUBMED:9529249] [PUBMED:8319905] [PUBMED:12654245]
Regulation of Telomerase [NCBI:137987] [Pathway Interaction Database:telomerasepathway] [PUBMED:12037663] [PUBMED:15048073] [PUBMED:10850490] [PUBMED:10601322] [PUBMED:12545159] [PUBMED:10637317] [PUBMED:11110707] [PUBMED:12681489] [PUBMED:15314656] [PUBMED:15824061] [PUBMED:16730176] [PUBMED:15371341] [PUBMED:16890531] [PUBMED:12181313] [PUBMED:9822378] [PUBMED:16843438] [PUBMED:9837921] [PUBMED:12699629] [PUBMED:12135483] [PUBMED:12151407] [PUBMED:16765199] [PUBMED:15655249] [PUBMED:15316005] [PUBMED:10224060] [PUBMED:15331176] [PUBMED:11074006] [PUBMED:16869756] [PUBMED:10888888] [PUBMED:16508638] [PUBMED:16135795] [PUBMED:14712220] [PUBMED:11191109] [PUBMED:11854288] [PUBMED:12956959] [PUBMED:15710386] [PUBMED:11433024] [PUBMED:14749375] [PUBMED:9130722] [PUBMED:12377759] [PUBMED:16785237] [PUBMED:15371412] [PUBMED:16166375] [PUBMED:12586360] [PUBMED:15843522] [PUBMED:12676087] [PUBMED:11274138] [PUBMED:15381700] [PUBMED:11191110] [PUBMED:16522649] [PUBMED:10837221] [PUBMED:10471503]
Role of LAT2/NTAL/LAB on calcium mobilization [NCBI:1269302] [REACTOME:R-HSA-2730905] [PUBMED:20643813] [PUBMED:17993265] [PUBMED:17420272]
SREBF and miR33 in cholesterol and lipid homeostasis [NCBI:755438] [WikiPathways:WP2011] [PUBMED:18046414] [PUBMED:20732877] [PUBMED:20855588] [PUBMED:17646659] [PUBMED:17347648] [PUBMED:17581637] [PUBMED:16799563] [PUBMED:20595232]
SREBP signalling [NCBI:219802] [WikiPathways:WP1982] [PUBMED:18835813] [PUBMED:20817729] [PUBMED:10500120] [PUBMED:15085196] [PUBMED:20541520] [PUBMED:10318878] [PUBMED:21816276] [PUBMED:19126544] [PUBMED:20145241] [PUBMED:22984430] [PUBMED:21240525] [PUBMED:21696544] [PUBMED:21664250] [PUBMED:10805775] [PUBMED:10224053] [PUBMED:19759400] [PUBMED:22031849] [PUBMED:15680331] [PUBMED:10397761] [PUBMED:16799563] [PUBMED:20595232] [PUBMED:17428920] [PUBMED:17296605] [PUBMED:8402897] [PUBMED:19706601] [PUBMED:16399501] [PUBMED:19158095] [PUBMED:17043353] [PUBMED:15899885] [PUBMED:20670887] [PUBMED:22927400] [PUBMED:20117946] [PUBMED:14765107] [PUBMED:15266058] [PUBMED:11358865] [PUBMED:22154484] [PUBMED:20103737] [PUBMED:22436747] [PUBMED:11591434] [PUBMED:16831124] [PUBMED:22684109] [PUBMED:21459323] [PUBMED:9488713] [PUBMED:23300015]
Senescence and Autophagy [NCBI:198780] [WikiPathways:WP615] [PUBMED:18555778]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:19648010] [PUBMED:17604717] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:15863030] [PUBMED:21252999] [PUBMED:19379690] [PUBMED:19536106] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:15450248] [PUBMED:15520807] [PUBMED:16939974] [PUBMED:18483217] [PUBMED:18043707] [PUBMED:19762341] [PUBMED:21781017] [PUBMED:17084981] [PUBMED:19619488] [PUBMED:17496910]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:15142631] [PUBMED:12297041]
Signaling by ERBB4 [NCBI:1269496] [REACTOME:R-HSA-1236394] [PUBMED:9275162] [PUBMED:9168115] [PUBMED:19193720] [PUBMED:16914727] [PUBMED:17545517] [PUBMED:7929212] [PUBMED:17018285] [PUBMED:9135143] [PUBMED:11679632] [PUBMED:15534001] [PUBMED:10744726] [PUBMED:8665853] [PUBMED:18653779] [PUBMED:7565730] [PUBMED:16978839] [PUBMED:15023535] [PUBMED:16061658] [PUBMED:17463226] [PUBMED:9556621] [PUBMED:18721752] [PUBMED:19047365] [PUBMED:12807903] [PUBMED:12869563] [PUBMED:10867024] [PUBMED:16778220] [PUBMED:16912174] [PUBMED:1706616] [PUBMED:8617750] [PUBMED:10722704]
Signaling by FGFR [NCBI:1269386] [REACTOME:R-HSA-190236] [PUBMED:12080084] [PUBMED:20602996] [PUBMED:15863030] [PUBMED:15567848] [PUBMED:7917292] [PUBMED:19247306] [PUBMED:16597617] [PUBMED:15863038]
Signaling by FGFR1 [NCBI:1269387] [REACTOME:R-HSA-5654736] [PUBMED:16597617] [PUBMED:19247306] [PUBMED:12080084] [PUBMED:15863038] [PUBMED:20602996] [PUBMED:15567848] [PUBMED:15863030] [PUBMED:7917292]
Signaling by FGFR2 [NCBI:1269399] [REACTOME:R-HSA-5654738] [PUBMED:16597617] [PUBMED:19247306] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:15863030] [PUBMED:20602996] [PUBMED:15567848] [PUBMED:7917292]
Signaling by FGFR3 [NCBI:1269409] [REACTOME:R-HSA-5654741] [PUBMED:19247306] [PUBMED:16597617] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:20602996] [PUBMED:15567848] [PUBMED:15863030] [PUBMED:7917292]
Signaling by FGFR4 [NCBI:1269419] [REACTOME:R-HSA-5654743] [PUBMED:12080084] [PUBMED:15863038] [PUBMED:7917292] [PUBMED:15863030] [PUBMED:19247306] [PUBMED:16597617] [PUBMED:15567848] [PUBMED:20602996]
Signaling by Insulin receptor [NCBI:1269428] [REACTOME:R-HSA-74752] [PUBMED:8276779]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signaling by SCF-KIT [NCBI:1269487] [REACTOME:R-HSA-1433557] [PUBMED:16483568] [PUBMED:7688988] [PUBMED:16475976] [PUBMED:19540337] [PUBMED:15526160] [PUBMED:17350321]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) [NCBI:1269617] [REACTOME:R-HSA-2404192] [PUBMED:18927274] [PUBMED:20098959] [PUBMED:21042815] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22044904] [PUBMED:22649417]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
Signaling by the B Cell Receptor (BCR) [NCBI:1269183] [REACTOME:R-HSA-983705] [PUBMED:1702903] [PUBMED:19065780] [PUBMED:16849466] [PUBMED:1081164] [PUBMED:2011584] [PUBMED:18596693] [PUBMED:1375264] [PUBMED:8580068] [PUBMED:4589993] [PUBMED:10648173] [PUBMED:7538118] [PUBMED:11901194] [PUBMED:8163536] [PUBMED:7688784] [PUBMED:1376928] [PUBMED:15489917] [PUBMED:7592958] [PUBMED:17052215] [PUBMED:7927516] [PUBMED:15509800] [PUBMED:7524079] [PUBMED:18818202] [PUBMED:18187424] [PUBMED:803528] [PUBMED:19909372] [PUBMED:20192804] [PUBMED:8306975] [PUBMED:19249086] [PUBMED:6335036] [PUBMED:20206686]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) [NCBI:137930] [Pathway Interaction Database:met_pathway] [PUBMED:10793146] [PUBMED:1718989] [PUBMED:1846706] [PUBMED:8906793] [PUBMED:10970810] [PUBMED:11929826] [PUBMED:10022866] [PUBMED:12951049] [PUBMED:11896055] [PUBMED:18073207] [PUBMED:11532961] [PUBMED:12475979] [PUBMED:9693375] [PUBMED:12138161] [PUBMED:17297451] [PUBMED:11046147] [PUBMED:12244132] [PUBMED:8607979] [PUBMED:15494312] [PUBMED:11162460] [PUBMED:17894413] [PUBMED:11809798] [PUBMED:9001234] [PUBMED:11069926] [PUBMED:16423831] [PUBMED:14636584] [PUBMED:2005882] [PUBMED:10995442] [PUBMED:20332103] [PUBMED:8380735] [PUBMED:17881575] [PUBMED:10618718] [PUBMED:11146548] [PUBMED:9591773] [PUBMED:19628037] [PUBMED:9252406] [PUBMED:18819921] [PUBMED:16858414] [PUBMED:19609305] [PUBMED:10558875] [PUBMED:17635922] [PUBMED:11134526] [PUBMED:16537482] [PUBMED:11741535] [PUBMED:12802068] [PUBMED:12894582] [PUBMED:1655790] [PUBMED:9748249] [PUBMED:11784715] [PUBMED:15314156] [PUBMED:10713700] [PUBMED:19272169] [PUBMED:1827664] [PUBMED:8387483] [PUBMED:19071214] [PUBMED:7513258] [PUBMED:16620780] [PUBMED:11118451] [PUBMED:17363898] [PUBMED:12941962] [PUBMED:16227611] [PUBMED:19289496] [PUBMED:11445578] [PUBMED:2541345] [PUBMED:7731718] [PUBMED:15735664] [PUBMED:11948414] [PUBMED:9487126] [PUBMED:11438654] [PUBMED:19525225] [PUBMED:9681449] [PUBMED:9668053] [PUBMED:11896575] [PUBMED:11894096] [PUBMED:12058075] [PUBMED:12147692] [PUBMED:9184210] [PUBMED:7499247] [PUBMED:17055484] [PUBMED:11896612] [PUBMED:2554238] [PUBMED:10679787] [PUBMED:19881549] [PUBMED:14684163] [PUBMED:17329361] [PUBMED:9886295] [PUBMED:12686592] [PUBMED:15452053] [PUBMED:10531383] [PUBMED:19109251] [PUBMED:10871282] [PUBMED:10516287] [PUBMED:9440692] [PUBMED:11352916] [PUBMED:17682062] [PUBMED:18346875] [PUBMED:10713050] [PUBMED:16952352] [PUBMED:10753869] [PUBMED:10734310] [PUBMED:1655405]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
TOR signaling [NCBI:198762] [WikiPathways:WP1471] [PUBMED:17041621] [PUBMED:16516475] [PUBMED:19143648] [PUBMED:17680028] [PUBMED:16469695]
TP53 Regulates Metabolic Genes [NCBI:1269655] [REACTOME:R-HSA-5628897] [PUBMED:18344994] [PUBMED:12453409] [PUBMED:20399660] [PUBMED:11545734] [PUBMED:15105503] [PUBMED:16839880] [PUBMED:17409411] [PUBMED:18198340] [PUBMED:18692468] [PUBMED:13298683] [PUBMED:15665293] [PUBMED:16728594] [PUBMED:23484829] [PUBMED:11959846] [PUBMED:17486094] [PUBMED:22682249] [PUBMED:9926927] [PUBMED:19696408] [PUBMED:22864287] [PUBMED:18391940] [PUBMED:17540029] [PUBMED:24366874] [PUBMED:20378837] [PUBMED:15059920] [PUBMED:19439913] [PUBMED:19822145] [PUBMED:12203114] [PUBMED:10716435]
TSH signaling pathway [NCBI:672446] [WikiPathways:WP2032]
TSLP Signaling Pathway [NCBI:672451] [WikiPathways:WP2203]
Thyroid hormone signaling pathway [NCBI:946598] [KEGG:hsa04919] [PUBMED:17983645] [PUBMED:20005976] [PUBMED:15345678] [PUBMED:16951130] [PUBMED:18329679] [PUBMED:20051527] [PUBMED:16214361] [PUBMED:17574003] [PUBMED:19716314] [PUBMED:19755667] [PUBMED:20868274] [PUBMED:21835053] [PUBMED:19295177] [PUBMED:16051672] [PUBMED:22484490] [PUBMED:23021374]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]
Type II diabetes mellitus [NCBI:83094] [KEGG:hsa04930] [NCBI:198791] [WikiPathways:WP1584] [PUBMED:9011569] [PUBMED:11390407] [PUBMED:11078440] [PUBMED:15759102] [PUBMED:15258147] [PUBMED:15823385] [PUBMED:15733744] [PUBMED:7491105] [PUBMED:11325516] [PUBMED:9974390] [PUBMED:12480546] [PUBMED:11272200] [PUBMED:15585596]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:16633338] [PUBMED:17344076] [PUBMED:13678960] [PUBMED:19230644]
VEGFR2 mediated vascular permeability [NCBI:1269484] [REACTOME:R-HSA-5218920] [PUBMED:17008595]
mTOR signaling pathway [NCBI:83059] [KEGG:hsa04150] [NCBI:138001] [Pathway Interaction Database:mtor_4pathway] [PUBMED:15306821] [PUBMED:17277771] [PUBMED:15988001] [PUBMED:15341740] [PUBMED:19963289] [PUBMED:14651849] [PUBMED:12869586] [PUBMED:15268862] [PUBMED:17928295] [PUBMED:15718470] [PUBMED:15681023] [PUBMED:17709744] [PUBMED:15928081] [PUBMED:16288292] [PUBMED:16919458] [PUBMED:9427642] [PUBMED:18046414] [PUBMED:12912918] [PUBMED:16286006] [PUBMED:16962653] [PUBMED:15928708] [PUBMED:19100909] [PUBMED:15780593] [PUBMED:17599906] [PUBMED:10364159] [PUBMED:15659337] [PUBMED:11500364] [PUBMED:12482958] [PUBMED:16109716] [PUBMED:16226444] [PUBMED:15276465] [PUBMED:11729323] [PUBMED:16244323] [PUBMED:18952604] [PUBMED:19114562] [PUBMED:17510057] [PUBMED:9465032] [PUBMED:16469695] [PUBMED:10567431] [PUBMED:9445476] [PUBMED:15851026] [PUBMED:18925875] [PUBMED:17461779] [PUBMED:15004009] [PUBMED:18604198] [PUBMED:15261137] [PUBMED:11287630] [PUBMED:18497260] [PUBMED:15071500] [PUBMED:12820960] [PUBMED:12604610] [PUBMED:18198340] [PUBMED:18411301] [PUBMED:15467718] [PUBMED:17053147] [PUBMED:17043309] [PUBMED:11500365] [PUBMED:12906785] [PUBMED:16452501] [PUBMED:18762023] [PUBMED:19225151] [PUBMED:11418588] [PUBMED:16341064] [PUBMED:15509864] [PUBMED:18439900] [PUBMED:18598780] [PUBMED:11175345] [PUBMED:16099218] [PUBMED:10357815] [PUBMED:18423201] [PUBMED:9271440] [PUBMED:19258318] [PUBMED:19446321] [PUBMED:17141160] [PUBMED:9204908] [PUBMED:15249583] [PUBMED:17386266] [PUBMED:12912989] [PUBMED:16404421] [PUBMED:18566587] [PUBMED:19211835] [PUBMED:16915281] [PUBMED:16288294] [PUBMED:12172553] [PUBMED:16002336] [PUBMED:15342917] [PUBMED:16288290] [PUBMED:1496022] [PUBMED:15545625] [PUBMED:11914378] [PUBMED:15624019] [PUBMED:12747827] [PUBMED:17693255] [PUBMED:14684182] [PUBMED:12231510]
mTOR signalling [NCBI:1269436] [REACTOME:R-HSA-165159] [PUBMED:21157483]
mTORC1-mediated signalling [NCBI:1269438] [REACTOME:R-HSA-166208] [PUBMED:23641065] [PUBMED:22500797]