full name
ribosomal protein S27

synonyms
MPS-1, MPS1, S27, RPS27, ENSG00000177954

HGNC
HGNC:10416

Entrez Gene
Gene:6232

ENSEMBL
ENSG00000177954

location
chr: 1
start: 153963239
stop: 153964631
strand: +

OMIM
OMIM:603702: RPS27
OMIM:617409: ?Diamond-Blackfan anemia 17

transcripts
NM_001030.4

pathways
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S [NCBI:1268683] [REACTOME:R-HSA-72662] [PUBMED:9732867] [PUBMED:592399] [PUBMED:641056] [PUBMED:6853548]
Cap-dependent Translation Initiation [NCBI:1268680] [REACTOME:R-HSA-72737]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Eukaryotic Translation Elongation [NCBI:1268690] [REACTOME:R-HSA-156842] [PUBMED:15189156]
Eukaryotic Translation Initiation [NCBI:1268679] [REACTOME:R-HSA-72613] [PUBMED:20444697]
Eukaryotic Translation Termination [NCBI:1268692] [REACTOME:R-HSA-72764] [PUBMED:15314182] [PUBMED:2684966]
Formation of a pool of free 40S subunits [NCBI:1268681] [REACTOME:R-HSA-72689]
Formation of the ternary complex, and subsequently, the 43S complex [NCBI:1268682] [REACTOME:R-HSA-72695] [PUBMED:641056] [PUBMED:1104615] [PUBMED:592399] [PUBMED:429297]
GTP hydrolysis and joining of the 60S ribosomal subunit [NCBI:1268686] [REACTOME:R-HSA-72706] [PUBMED:11018020] [PUBMED:1095581] [PUBMED:429297] [PUBMED:641056] [PUBMED:1856230] [PUBMED:592398] [PUBMED:10659855] [PUBMED:592399]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Influenza Infection [NCBI:1269108] [REACTOME:R-HSA-168254]
Influenza Life Cycle [NCBI:1269109] [REACTOME:R-HSA-168255]
Influenza Viral RNA Transcription and Replication [NCBI:1269115] [REACTOME:R-HSA-168273] [PUBMED:2214032] [PUBMED:6863242] [PUBMED:6616622] [PUBMED:6269803]
L13a-mediated translational silencing of Ceruloplasmin expression [NCBI:1268688] [REACTOME:R-HSA-156827] [PUBMED:14567916]
M Phase [NCBI:1269810] [REACTOME:R-HSA-68886]
Major pathway of rRNA processing in the nucleolus and cytosol [NCBI:1383086] [REACTOME:R-HSA-6791226] [PUBMED:25346433] [PUBMED:11862453] [PUBMED:23973377] [PUBMED:21318072] [PUBMED:23412654] [PUBMED:12150911] [PUBMED:25877921] [PUBMED:21956940] [PUBMED:22342225] [PUBMED:12068309]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Mitotic Anaphase [NCBI:1269825] [REACTOME:R-HSA-68882]
Mitotic Metaphase and Anaphase [NCBI:1269823] [REACTOME:R-HSA-2555396]
Mitotic Prometaphase [NCBI:1269820] [REACTOME:R-HSA-68877]
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) [NCBI:1269717] [REACTOME:R-HSA-975957] [PUBMED:19859661] [PUBMED:21496649] [PUBMED:17352659] [PUBMED:20795950] [PUBMED:19359157] [PUBMED:17531985] [PUBMED:17671086] [PUBMED:19410547]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) [NCBI:1269718] [REACTOME:R-HSA-975956] [PUBMED:20795950] [PUBMED:18447580] [PUBMED:17671086] [PUBMED:17531985] [PUBMED:19359157] [PUBMED:19859661] [PUBMED:17352659] [PUBMED:18447585] [PUBMED:18256688]
Nonsense-Mediated Decay (NMD) [NCBI:1269716] [REACTOME:R-HSA-927802] [PUBMED:18524595] [PUBMED:17671086] [PUBMED:19359157] [PUBMED:17531985] [PUBMED:17352659] [PUBMED:21496649] [PUBMED:19859661] [PUBMED:20795950] [PUBMED:19010255]
Peptide chain elongation [NCBI:1268691] [REACTOME:R-HSA-156902] [PUBMED:12297040]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases Activate Formins [NCBI:1269519] [REACTOME:R-HSA-5663220] [PUBMED:20233848] [PUBMED:15507212] [PUBMED:16292343] [PUBMED:12906795] [PUBMED:11779461] [PUBMED:21397845] [PUBMED:12577064] [PUBMED:17198702] [PUBMED:15006353] [PUBMED:20101212] [PUBMED:15944396] [PUBMED:10678165] [PUBMED:16943183] [PUBMED:16439214] [PUBMED:16472745] [PUBMED:10958683] [PUBMED:12732141] [PUBMED:15085137] [PUBMED:24914801] [PUBMED:9497258] [PUBMED:21576392] [PUBMED:21868368]
Resolution of Sister Chromatid Cohesion [NCBI:1269821] [REACTOME:R-HSA-2500257] [PUBMED:16541025] [PUBMED:15339662] [PUBMED:17112726] [PUBMED:9649503] [PUBMED:21111234] [PUBMED:15737063] [PUBMED:17113138] [PUBMED:21987589] [PUBMED:14730319] [PUBMED:11509732] [PUBMED:19696148] [PUBMED:21878504] [PUBMED:15723797]
Ribosomal scanning and start codon recognition [NCBI:1268685] [REACTOME:R-HSA-72702] [PUBMED:9732867] [PUBMED:7000367] [PUBMED:592399] [PUBMED:641056]
Ribosome [NCBI:83036] [KEGG:hsa03010] [PUBMED:10476960] [PUBMED:11014182] [PUBMED:10937989] [PUBMED:10937990] [PUBMED:11014183] [PUBMED:10476961] [PUBMED:10497122]
SRP-dependent cotranslational protein targeting to membrane [NCBI:1268689] [REACTOME:R-HSA-1799339]
Selenoamino acid metabolism [NCBI:1339149] [REACTOME:R-HSA-2408522] [PUBMED:20812787]
Selenocysteine synthesis [NCBI:1339156] [REACTOME:R-HSA-2408557] [PUBMED:19747061] [PUBMED:20623998] [PUBMED:18252769]
Separation of Sister Chromatids [NCBI:1269826] [REACTOME:R-HSA-2467813] [PUBMED:11081627] [PUBMED:10411507] [PUBMED:12070128] [PUBMED:12194817] [PUBMED:11509732]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Translation [NCBI:1268678] [REACTOME:R-HSA-72766]
Translation initiation complex formation [NCBI:1268684] [REACTOME:R-HSA-72649] [PUBMED:6853548] [PUBMED:641056] [PUBMED:9732867] [PUBMED:592399]
Viral mRNA Translation [NCBI:1269120] [REACTOME:R-HSA-192823] [PUBMED:16630668]
rRNA processing [NCBI:1383085] [REACTOME:R-HSA-72312] [PUBMED:20174677] [PUBMED:21956940] [PUBMED:25346433] [PUBMED:25590339] [PUBMED:15193314] [PUBMED:11862453] [PUBMED:19917616] [PUBMED:24490730]
rRNA processing in the nucleus and cytosol [NCBI:1427846] [REACTOME:R-HSA-8868773] [PUBMED:24490730] [PUBMED:21956940] [PUBMED:25346433]