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Genes
RPS27
Gene - RPS27
full name
ribosomal protein S27
synonyms
MPS-1, MPS1, S27, RPS27, ENSG00000177954
HGNC
HGNC:10416
Entrez Gene
Gene:6232
ENSEMBL
ENSG00000177954
location
chr: 1
start: 153963239
stop: 153964631
strand: +
OMIM
OMIM:603702
: RPS27
OMIM:617409
: ?Diamond-Blackfan anemia 17
transcripts
NM_001030.4
pathways
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
[NCBI:1268683]
[REACTOME:R-HSA-72662]
[PUBMED:9732867]
[PUBMED:592399]
[PUBMED:641056]
[PUBMED:6853548]
Cap-dependent Translation Initiation
[NCBI:1268680]
[REACTOME:R-HSA-72737]
Cell Cycle
[NCBI:1269741]
[REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic
[NCBI:1269763]
[REACTOME:R-HSA-69278]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Eukaryotic Translation Elongation
[NCBI:1268690]
[REACTOME:R-HSA-156842]
[PUBMED:15189156]
Eukaryotic Translation Initiation
[NCBI:1268679]
[REACTOME:R-HSA-72613]
[PUBMED:20444697]
Eukaryotic Translation Termination
[NCBI:1268692]
[REACTOME:R-HSA-72764]
[PUBMED:15314182]
[PUBMED:2684966]
Formation of a pool of free 40S subunits
[NCBI:1268681]
[REACTOME:R-HSA-72689]
Formation of the ternary complex, and subsequently, the 43S complex
[NCBI:1268682]
[REACTOME:R-HSA-72695]
[PUBMED:641056]
[PUBMED:1104615]
[PUBMED:592399]
[PUBMED:429297]
GTP hydrolysis and joining of the 60S ribosomal subunit
[NCBI:1268686]
[REACTOME:R-HSA-72706]
[PUBMED:11018020]
[PUBMED:1095581]
[PUBMED:429297]
[PUBMED:641056]
[PUBMED:1856230]
[PUBMED:592398]
[PUBMED:10659855]
[PUBMED:592399]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Infectious disease
[NCBI:1269056]
[REACTOME:R-HSA-5663205]
Influenza Infection
[NCBI:1269108]
[REACTOME:R-HSA-168254]
Influenza Life Cycle
[NCBI:1269109]
[REACTOME:R-HSA-168255]
Influenza Viral RNA Transcription and Replication
[NCBI:1269115]
[REACTOME:R-HSA-168273]
[PUBMED:2214032]
[PUBMED:6863242]
[PUBMED:6616622]
[PUBMED:6269803]
L13a-mediated translational silencing of Ceruloplasmin expression
[NCBI:1268688]
[REACTOME:R-HSA-156827]
[PUBMED:14567916]
M Phase
[NCBI:1269810]
[REACTOME:R-HSA-68886]
Major pathway of rRNA processing in the nucleolus and cytosol
[NCBI:1383086]
[REACTOME:R-HSA-6791226]
[PUBMED:25346433]
[PUBMED:11862453]
[PUBMED:23973377]
[PUBMED:21318072]
[PUBMED:23412654]
[PUBMED:12150911]
[PUBMED:25877921]
[PUBMED:21956940]
[PUBMED:22342225]
[PUBMED:12068309]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives
[NCBI:1270158]
[REACTOME:R-HSA-71291]
Metabolism of proteins
[NCBI:1268677]
[REACTOME:R-HSA-392499]
Mitotic Anaphase
[NCBI:1269825]
[REACTOME:R-HSA-68882]
Mitotic Metaphase and Anaphase
[NCBI:1269823]
[REACTOME:R-HSA-2555396]
Mitotic Prometaphase
[NCBI:1269820]
[REACTOME:R-HSA-68877]
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
[NCBI:1269717]
[REACTOME:R-HSA-975957]
[PUBMED:19859661]
[PUBMED:21496649]
[PUBMED:17352659]
[PUBMED:20795950]
[PUBMED:19359157]
[PUBMED:17531985]
[PUBMED:17671086]
[PUBMED:19410547]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
[NCBI:1269718]
[REACTOME:R-HSA-975956]
[PUBMED:20795950]
[PUBMED:18447580]
[PUBMED:17671086]
[PUBMED:17531985]
[PUBMED:19359157]
[PUBMED:19859661]
[PUBMED:17352659]
[PUBMED:18447585]
[PUBMED:18256688]
Nonsense-Mediated Decay (NMD)
[NCBI:1269716]
[REACTOME:R-HSA-927802]
[PUBMED:18524595]
[PUBMED:17671086]
[PUBMED:19359157]
[PUBMED:17531985]
[PUBMED:17352659]
[PUBMED:21496649]
[PUBMED:19859661]
[PUBMED:20795950]
[PUBMED:19010255]
Peptide chain elongation
[NCBI:1268691]
[REACTOME:R-HSA-156902]
[PUBMED:12297040]
RHO GTPase Effectors
[NCBI:1269509]
[REACTOME:R-HSA-195258]
[PUBMED:9694656]
[PUBMED:18066052]
[PUBMED:11018042]
[PUBMED:10470034]
[PUBMED:8702756]
[PUBMED:21730051]
[PUBMED:8571126]
[PUBMED:19513348]
[PUBMED:17244649]
[PUBMED:11145705]
[PUBMED:24128008]
[PUBMED:23716662]
[PUBMED:8617235]
[PUBMED:8543060]
[PUBMED:11804587]
[PUBMED:24969695]
[PUBMED:12635176]
[PUBMED:12778124]
[PUBMED:18006505]
[PUBMED:1660188]
[PUBMED:21351730]
[PUBMED:16507994]
[PUBMED:14595335]
[PUBMED:10072071]
[PUBMED:10591629]
[PUBMED:10753910]
[PUBMED:23875749]
[PUBMED:17151359]
[PUBMED:10652353]
[PUBMED:12221077]
[PUBMED:10559936]
[PUBMED:12783890]
[PUBMED:11948177]
[PUBMED:18237546]
[PUBMED:16079795]
[PUBMED:10924361]
[PUBMED:14514689]
[PUBMED:8107774]
[PUBMED:8756646]
[PUBMED:16979770]
[PUBMED:16636067]
[PUBMED:9751706]
[PUBMED:10619026]
[PUBMED:23444367]
[PUBMED:15546864]
[PUBMED:12473120]
[PUBMED:8816443]
[PUBMED:9199170]
[PUBMED:12514133]
[PUBMED:16762923]
[PUBMED:12110184]
[PUBMED:16431929]
[PUBMED:10975528]
[PUBMED:10940294]
[PUBMED:9535855]
[PUBMED:7559638]
[PUBMED:11162552]
[PUBMED:19737400]
[PUBMED:9988689]
[PUBMED:12732141]
[PUBMED:8798539]
[PUBMED:24914801]
[PUBMED:11689693]
[PUBMED:8769096]
[PUBMED:9368021]
RHO GTPases Activate Formins
[NCBI:1269519]
[REACTOME:R-HSA-5663220]
[PUBMED:20233848]
[PUBMED:15507212]
[PUBMED:16292343]
[PUBMED:12906795]
[PUBMED:11779461]
[PUBMED:21397845]
[PUBMED:12577064]
[PUBMED:17198702]
[PUBMED:15006353]
[PUBMED:20101212]
[PUBMED:15944396]
[PUBMED:10678165]
[PUBMED:16943183]
[PUBMED:16439214]
[PUBMED:16472745]
[PUBMED:10958683]
[PUBMED:12732141]
[PUBMED:15085137]
[PUBMED:24914801]
[PUBMED:9497258]
[PUBMED:21576392]
[PUBMED:21868368]
Resolution of Sister Chromatid Cohesion
[NCBI:1269821]
[REACTOME:R-HSA-2500257]
[PUBMED:16541025]
[PUBMED:15339662]
[PUBMED:17112726]
[PUBMED:9649503]
[PUBMED:21111234]
[PUBMED:15737063]
[PUBMED:17113138]
[PUBMED:21987589]
[PUBMED:14730319]
[PUBMED:11509732]
[PUBMED:19696148]
[PUBMED:21878504]
[PUBMED:15723797]
Ribosomal scanning and start codon recognition
[NCBI:1268685]
[REACTOME:R-HSA-72702]
[PUBMED:9732867]
[PUBMED:7000367]
[PUBMED:592399]
[PUBMED:641056]
Ribosome
[NCBI:83036]
[KEGG:hsa03010]
[PUBMED:10476960]
[PUBMED:11014182]
[PUBMED:10937989]
[PUBMED:10937990]
[PUBMED:11014183]
[PUBMED:10476961]
[PUBMED:10497122]
SRP-dependent cotranslational protein targeting to membrane
[NCBI:1268689]
[REACTOME:R-HSA-1799339]
Selenoamino acid metabolism
[NCBI:1339149]
[REACTOME:R-HSA-2408522]
[PUBMED:20812787]
Selenocysteine synthesis
[NCBI:1339156]
[REACTOME:R-HSA-2408557]
[PUBMED:19747061]
[PUBMED:20623998]
[PUBMED:18252769]
Separation of Sister Chromatids
[NCBI:1269826]
[REACTOME:R-HSA-2467813]
[PUBMED:11081627]
[PUBMED:10411507]
[PUBMED:12070128]
[PUBMED:12194817]
[PUBMED:11509732]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]
Translation
[NCBI:1268678]
[REACTOME:R-HSA-72766]
Translation initiation complex formation
[NCBI:1268684]
[REACTOME:R-HSA-72649]
[PUBMED:6853548]
[PUBMED:641056]
[PUBMED:9732867]
[PUBMED:592399]
Viral mRNA Translation
[NCBI:1269120]
[REACTOME:R-HSA-192823]
[PUBMED:16630668]
rRNA processing
[NCBI:1383085]
[REACTOME:R-HSA-72312]
[PUBMED:20174677]
[PUBMED:21956940]
[PUBMED:25346433]
[PUBMED:25590339]
[PUBMED:15193314]
[PUBMED:11862453]
[PUBMED:19917616]
[PUBMED:24490730]
rRNA processing in the nucleus and cytosol
[NCBI:1427846]
[REACTOME:R-HSA-8868773]
[PUBMED:24490730]
[PUBMED:21956940]
[PUBMED:25346433]