full name
lysine methyltransferase 2A

synonyms
ALL-1, CXXC7, HRX, HTRX1, MLL, MLL%2FGAS7, MLL1A, TET1-MLL, TRX1, WDSTS, KMT2A, ENSG00000118058

HGNC
HGNC:7132

Entrez Gene
Gene:4297

ENSEMBL
ENSG00000118058
ENSG00000267910

location
chr: 11
start: 118307205
stop: 118397539
strand: +

OMIM
OMIM:159555: KMT2A (Autosomal dominant inheritance)
OMIM:605130: Wiedemann-Steiner syndrome

transcripts
NM_001197104.1
NM_005933.3

pathways
Chromatin modifying enzymes [NCBI:1270434] [REACTOME:R-HSA-3247509]
Chromatin organization [NCBI:1270433] [REACTOME:R-HSA-4839726] [PUBMED:21342762] [PUBMED:15598472]
Lysine degradation [NCBI:82956] [KEGG:hsa00310] [PUBMED:1682209] [PUBMED:11802770]
PKMTs methylate histone lysines [NCBI:1270438] [REACTOME:R-HSA-3214841] [PUBMED:11893494] [PUBMED:19721445]
Senescence and Autophagy [NCBI:198780] [WikiPathways:WP615] [PUBMED:18555778]
Transcriptional misregulation in cancer [NCBI:523016] [KEGG:hsa05202] [PUBMED:20190806] [PUBMED:11313274] [PUBMED:20145147] [PUBMED:19472090] [PUBMED:11863357] [PUBMED:18330902] [PUBMED:12032780] [PUBMED:19564705] [PUBMED:19738075] [PUBMED:15160934] [PUBMED:15024077] [PUBMED:21765642] [PUBMED:14630078] [PUBMED:17101797] [PUBMED:12511414] [PUBMED:15688424] [PUBMED:15985538] [PUBMED:21747944] [PUBMED:19406209] [PUBMED:15826838] [PUBMED:12527902] [PUBMED:10350329] [PUBMED:16946003] [PUBMED:17250957] [PUBMED:18563191] [PUBMED:17505060] [PUBMED:21779514] [PUBMED:11340171] [PUBMED:12529654] [PUBMED:18855877] [PUBMED:12393465] [PUBMED:20153925] [PUBMED:19855079] [PUBMED:18648544] [PUBMED:10717473] [PUBMED:12130514] [PUBMED:19059936] [PUBMED:18172298] [PUBMED:16169901] [PUBMED:18850010] [PUBMED:19422821] [PUBMED:19233641] [PUBMED:14701735] [PUBMED:10500199] [PUBMED:19141473] [PUBMED:10537274] [PUBMED:18457914] [PUBMED:15826834] [PUBMED:15156184] [PUBMED:10784387] [PUBMED:17024155] [PUBMED:20974671] [PUBMED:19075677] [PUBMED:12527906] [PUBMED:15644444] [PUBMED:21849159] [PUBMED:19075268] [PUBMED:20863376] [PUBMED:21123453] [PUBMED:17327229] [PUBMED:17222504] [PUBMED:11607818] [PUBMED:12670461] [PUBMED:20490326] [PUBMED:20478527] [PUBMED:14998494] [PUBMED:19133982] [PUBMED:21518926]