full name
phospholipase C zeta 1

synonyms
NYD-SP27, PLC-zeta-1, PLCzeta, PLCZ1, ENSG00000139151

HGNC
HGNC:19218

Entrez Gene
Gene:89869

ENSEMBL
ENSG00000139151

location
chr: 12
start: 18836110
stop: 18891020
strand: -

OMIM
OMIM:608075: PLCZ1
OMIM:617214: ?Spermatogenic failure 17

transcripts
NM_033123.3
NR_073075.1

pathways
Calcium signaling pathway [NCBI:83050] [KEGG:hsa04020] [PUBMED:11080247] [PUBMED:14572802] [PUBMED:11413485] [PUBMED:22129055] [PUBMED:10508738] [PUBMED:15000521] [PUBMED:9235901] [PUBMED:7861177] [PUBMED:9149541] [PUBMED:14517314] [PUBMED:15111104] [PUBMED:11698232] [PUBMED:10331643] [PUBMED:12838335] [PUBMED:8125957] [PUBMED:19172794] [PUBMED:10997573] [PUBMED:21338471] [PUBMED:11299192] [PUBMED:22002090] [PUBMED:12972622]
D-myo-inositol (1,4,5)-trisphosphate biosynthesis [NCBI:545326] [BIOCYC:HUMAN_PWY-6351] [PUBMED:6232463] [PUBMED:18341203] [PUBMED:438153] [PUBMED:6146314] [PUBMED:6605482] [PUBMED:164246] [PUBMED:9367159] [PUBMED:12897244] [PUBMED:12117804] [PUBMED:17895620] [PUBMED:11395409]
D-myo-inositol-5-phosphate metabolism [NCBI:545315] [BIOCYC:HUMAN_PWY-6367] [PUBMED:164246] [PUBMED:16365287] [PUBMED:18774718] [PUBMED:17008356] [PUBMED:9367159] [PUBMED:11676921]
Inositol phosphate metabolism [NCBI:82987] [KEGG:hsa00562] [NCBI:1269988] [REACTOME:R-HSA-1483249] [PUBMED:17943301] [PUBMED:18310071] [PUBMED:20414202] [PUBMED:11331907] [PUBMED:20359876] [PUBMED:14993306] [PUBMED:16781889]
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [NCBI:413400] [KEGG:hsa_M00130]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Oocyte meiosis [NCBI:126909] [KEGG:hsa04114] [PUBMED:16760654] [PUBMED:17480229] [PUBMED:15136768] [PUBMED:18946022] [PUBMED:18598214] [PUBMED:16518630] [PUBMED:18631137] [PUBMED:15182704] [PUBMED:15182701] [PUBMED:16554437] [PUBMED:14691134] [PUBMED:18550795] [PUBMED:18096427] [PUBMED:14517314] [PUBMED:18311174]
Phosphatidylinositol signaling system [NCBI:83052] [KEGG:hsa04070] [PUBMED:19439500] [PUBMED:19580826]
Synthesis of IP3 and IP4 in the cytosol [NCBI:1269989] [REACTOME:R-HSA-1855204] [PUBMED:11331907] [PUBMED:20414202]
Thyroid hormone signaling pathway [NCBI:946598] [KEGG:hsa04919] [PUBMED:20005976] [PUBMED:17983645] [PUBMED:15345678] [PUBMED:16951130] [PUBMED:16214361] [PUBMED:18329679] [PUBMED:20051527] [PUBMED:17574003] [PUBMED:19716314] [PUBMED:19755667] [PUBMED:20868274] [PUBMED:21835053] [PUBMED:16051672] [PUBMED:19295177] [PUBMED:23021374] [PUBMED:22484490]
phospholipases [NCBI:142419] [BIOCYC:HUMAN_LIPASYN-PWY]
superpathway of inositol phosphate compounds [NCBI:547492] [BIOCYC:HUMAN_PWY-6371]