Logo
full name
integrin subunit alpha 5

synonyms
CD49e, FNRA, VLA5A, ITGA5, ENSG00000161638

HGNC
HGNC:6141

Entrez Gene
Gene:3678

ENSEMBL
ENSG00000161638

location
chr: 12
start: 54789045
stop: 54813050
strand: -

transcripts
ENST00000293379.4

pathways
Angiopoietin receptor Tie2-mediated signaling [NCBI:137917] [Pathway Interaction Database:angiopoietinreceptor_pathway] [PUBMED:9204896] [PUBMED:12609966] [PUBMED:14726409] [PUBMED:11157678] [PUBMED:10347092] [PUBMED:11967990] [PUBMED:15162796] [PUBMED:11289054] [PUBMED:12759249] [PUBMED:10051567] [PUBMED:12824293] [PUBMED:16895971] [PUBMED:10807867] [PUBMED:12933576] [PUBMED:11513602] [PUBMED:12074640] [PUBMED:8980223] [PUBMED:14665640] [PUBMED:15132996] [PUBMED:10944458] [PUBMED:11230987] [PUBMED:15242771] [PUBMED:10585289] [PUBMED:16061664] [PUBMED:10376602] [PUBMED:15350545] [PUBMED:9632797] [PUBMED:10625301] [PUBMED:9926914] [PUBMED:17189382] [PUBMED:11139469] [PUBMED:11689432] [PUBMED:11416142] [PUBMED:11166279] [PUBMED:15284220] [PUBMED:15985432] [PUBMED:16049136] [PUBMED:16157706] [PUBMED:10521483] [PUBMED:12816861] [PUBMED:9478921] [PUBMED:10376603] [PUBMED:15769741] [PUBMED:12890486] [PUBMED:14749497] [PUBMED:7561682] [PUBMED:11801735] [PUBMED:12665569] [PUBMED:12117724] [PUBMED:9764820]
Arrhythmogenic right ventricular cardiomyopathy (ARVC) [NCBI:117293] [KEGG:hsa05412] [PUBMED:16823481] [PUBMED:19205777] [PUBMED:11716909] [PUBMED:12270949] [PUBMED:18382419] [PUBMED:16101641] [PUBMED:16124859] [PUBMED:17413274]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Bacterial invasion of epithelial cells [NCBI:149807] [KEGG:hsa05100] [PUBMED:17298394] [PUBMED:16406780] [PUBMED:19185531] [PUBMED:19157959] [PUBMED:17719540] [PUBMED:19296488]
Cell surface interactions at the vascular wall [NCBI:1269373] [REACTOME:R-HSA-202733] [PUBMED:17525755] [PUBMED:11282294] [PUBMED:10798271] [PUBMED:8578462] [PUBMED:14615387] [PUBMED:16115029]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Dilated cardiomyopathy [NCBI:121494] [KEGG:hsa05414] [PUBMED:11524405] [PUBMED:11805847] [PUBMED:12270949] [PUBMED:14522402] [PUBMED:19017683] [PUBMED:15146239] [PUBMED:18672201] [PUBMED:19273156] [PUBMED:19246813] [PUBMED:11716909] [PUBMED:16817756]
ECM-receptor interaction [NCBI:83068] [KEGG:hsa04512] [PUBMED:7698997] [PUBMED:15381249] [PUBMED:12796473] [PUBMED:11331578] [PUBMED:15036264] [PUBMED:12125070] [PUBMED:12736199] [PUBMED:15229478] [PUBMED:11572082] [PUBMED:10617638] [PUBMED:12845610] [PUBMED:12921709]
Elastic fibre formation [NCBI:1270251] [REACTOME:R-HSA-1566948] [PUBMED:16261592]
Extracellular matrix organization [NCBI:1270244] [REACTOME:R-HSA-1474244] [PUBMED:21123617] [PUBMED:21917992] [PUBMED:12845610]
Fibronectin matrix formation [NCBI:1270250] [REACTOME:R-HSA-1566977] [PUBMED:20690820]
Focal adhesion [NCBI:83067] [KEGG:hsa04510] [PUBMED:10698680] [PUBMED:15459662] [PUBMED:14756624] [PUBMED:11573199] [PUBMED:12640026] [PUBMED:15179030] [PUBMED:15108811] [PUBMED:15053919] [PUBMED:11082269] [PUBMED:15034601] [PUBMED:12235283] [PUBMED:14519391] [PUBMED:11146675] [PUBMED:11229600] [PUBMED:15688067] [PUBMED:14744429] [PUBMED:11882383]
Hematopoietic cell lineage [NCBI:83078] [KEGG:hsa04640] [PUBMED:15629410] [PUBMED:15738953] [PUBMED:11905810] [PUBMED:15156179] [PUBMED:12415312] [PUBMED:14985712] [PUBMED:9927518] [PUBMED:15771582] [PUBMED:14670296] [PUBMED:12360214]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Hypertrophic cardiomyopathy (HCM) [NCBI:114229] [KEGG:hsa05410] [PUBMED:11805847] [PUBMED:18572189] [PUBMED:14711353] [PUBMED:19136482] [PUBMED:18056765] [PUBMED:11225594] [PUBMED:12844200] [PUBMED:10615904] [PUBMED:11716909] [PUBMED:11371514] [PUBMED:12270949]
Integrin cell surface interactions [NCBI:1270260] [REACTOME:R-HSA-216083] [PUBMED:10215583] [PUBMED:15147720] [PUBMED:12231361] [PUBMED:8866399] [PUBMED:19273203]
L1CAM interactions [NCBI:1270323] [REACTOME:R-HSA-373760] [PUBMED:9211984] [PUBMED:18760361] [PUBMED:14709786] [PUBMED:17189949] [PUBMED:19356150]
MicroRNAs in cancer [NCBI:852705] [KEGG:hsa05206] [PUBMED:23075324] [PUBMED:21742789] [PUBMED:22351564] [PUBMED:18817506] [PUBMED:22345301] [PUBMED:21402473] [PUBMED:22926415] [PUBMED:23165235] [PUBMED:19630570] [PUBMED:21565290] [PUBMED:23091478] [PUBMED:23462054] [PUBMED:23316212] [PUBMED:19773200] [PUBMED:22035854] [PUBMED:20221895] [PUBMED:20345848] [PUBMED:22580099] [PUBMED:20128019]
PI3K-Akt signaling pathway [NCBI:692234] [KEGG:hsa04151] [PUBMED:12048182] [PUBMED:11357143] [PUBMED:21440011] [PUBMED:15209374] [PUBMED:12669022] [PUBMED:18842113] [PUBMED:16847462] [PUBMED:12660731] [PUBMED:17360849] [PUBMED:9838078] [PUBMED:15505410] [PUBMED:16248975] [PUBMED:12531180] [PUBMED:21779440] [PUBMED:16187290] [PUBMED:15784165] [PUBMED:21620960]
Pertussis [NCBI:218111] [KEGG:hsa05133] [PUBMED:20610650] [PUBMED:12701623] [PUBMED:15201703] [PUBMED:18401006] [PUBMED:20210554] [PUBMED:16622221] [PUBMED:17148436] [PUBMED:21204863] [PUBMED:20404851] [PUBMED:10540218] [PUBMED:16999837] [PUBMED:16481212] [PUBMED:16863919] [PUBMED:16390441] [PUBMED:21423776] [PUBMED:17328678] [PUBMED:12915094]
Phagosome [NCBI:153910] [KEGG:hsa04145] [PUBMED:17637737] [PUBMED:18513324] [PUBMED:15894272] [PUBMED:10684585] [PUBMED:18492791] [PUBMED:15036145] [PUBMED:17245426]
Proteoglycans in cancer [NCBI:782000] [KEGG:hsa05205] [PUBMED:19433454] [PUBMED:20655987] [PUBMED:18798267] [PUBMED:10633082] [PUBMED:10687947] [PUBMED:22735579] [PUBMED:24412155] [PUBMED:9346940] [PUBMED:22087031] [PUBMED:22194599] [PUBMED:14711376] [PUBMED:19255147] [PUBMED:15655247] [PUBMED:11717317] [PUBMED:17971838] [PUBMED:18413366] [PUBMED:20974860] [PUBMED:11830493] [PUBMED:23058688] [PUBMED:18450475] [PUBMED:12748184] [PUBMED:19733083] [PUBMED:18812315] [PUBMED:12509413] [PUBMED:21155971] [PUBMED:11931647] [PUBMED:18949819] [PUBMED:12729888] [PUBMED:15994311] [PUBMED:23305321] [PUBMED:18505598] [PUBMED:22563565] [PUBMED:22033227]
Regulation of actin cytoskeleton [NCBI:83089] [KEGG:hsa04810] [PUBMED:11152757] [PUBMED:11082272] [PUBMED:10574699] [PUBMED:11082269] [PUBMED:14657486] [PUBMED:14744429] [PUBMED:12700767]
Shigellosis [NCBI:83104] [KEGG:hsa05131] [PUBMED:11379633] [PUBMED:10491394] [PUBMED:17173036] [PUBMED:18202440] [PUBMED:17095701] [PUBMED:16622194] [PUBMED:16413487] [PUBMED:18005683] [PUBMED:15731041] [PUBMED:15073367] [PUBMED:12856283] [PUBMED:16939534] [PUBMED:17060328] [PUBMED:12065406] [PUBMED:8376337] [PUBMED:11207560] [PUBMED:8642302] [PUBMED:12356723] [PUBMED:15694852] [PUBMED:10369666] [PUBMED:14638419] [PUBMED:16441429] [PUBMED:16162672] [PUBMED:17719540] [PUBMED:7665485] [PUBMED:18059288] [PUBMED:18005697] [PUBMED:19165331] [PUBMED:12828640] [PUBMED:17662586] [PUBMED:9176079] [PUBMED:7591128] [PUBMED:15318166] [PUBMED:15950937]
Signal transduction by L1 [NCBI:1270326] [REACTOME:R-HSA-445144] [PUBMED:15597056] [PUBMED:12721290] [PUBMED:10608864] [PUBMED:17189949] [PUBMED:16597699] [PUBMED:10818153]
Signaling events mediated by focal adhesion kinase [NCBI:169348] [Pathway Interaction Database:fak_pathway] [PUBMED:18793427] [PUBMED:15340073] [PUBMED:16054026] [PUBMED:12932330] [PUBMED:20038548] [PUBMED:7542255] [PUBMED:8939916] [PUBMED:16000375] [PUBMED:10856236] [PUBMED:17164291] [PUBMED:9148935] [PUBMED:10893408] [PUBMED:10512882] [PUBMED:11839772] [PUBMED:11553710] [PUBMED:7566154] [PUBMED:20018869] [PUBMED:12839996] [PUBMED:11799111] [PUBMED:16308318] [PUBMED:11331870] [PUBMED:12681445] [PUBMED:11369769] [PUBMED:11739801] [PUBMED:9860979] [PUBMED:8947559] [PUBMED:11017882] [PUBMED:7509446] [PUBMED:10791986] [PUBMED:9128257] [PUBMED:19297531] [PUBMED:17325207] [PUBMED:17093062] [PUBMED:10593973] [PUBMED:20308429] [PUBMED:8922390] [PUBMED:19776348] [PUBMED:9374537] [PUBMED:10976102] [PUBMED:10373530] [PUBMED:19883375] [PUBMED:10430888] [PUBMED:12820964] [PUBMED:9425168] [PUBMED:14743221] [PUBMED:18854312] [PUBMED:12952943] [PUBMED:15962308] [PUBMED:11927607] [PUBMED:15657076] [PUBMED:15039571] [PUBMED:18303050] [PUBMED:11799401] [PUBMED:15247219] [PUBMED:12702722] [PUBMED:10998418] [PUBMED:7615549] [PUBMED:18195107] [PUBMED:9032297] [PUBMED:10873807] [PUBMED:10777511] [PUBMED:12502711] [PUBMED:9566877] [PUBMED:8649427] [PUBMED:19473962] [PUBMED:9808620] [PUBMED:15914540] [PUBMED:1385445] [PUBMED:18223254] [PUBMED:11909938] [PUBMED:15166238] [PUBMED:7622520] [PUBMED:8824286] [PUBMED:8662921] [PUBMED:8707856] [PUBMED:10330411] [PUBMED:10446223] [PUBMED:20150423] [PUBMED:11604500] [PUBMED:9234699] [PUBMED:18773890] [PUBMED:18757826] [PUBMED:9864370] [PUBMED:7983066] [PUBMED:18322799] [PUBMED:12006652] [PUBMED:16461767] [PUBMED:10385525] [PUBMED:14676198] [PUBMED:9858476] [PUBMED:18070912] [PUBMED:11058585] [PUBMED:12890755] [PUBMED:9184223] [PUBMED:12058076] [PUBMED:12226752] [PUBMED:19435801] [PUBMED:10212207] [PUBMED:10521463] [PUBMED:16159962] [PUBMED:7579684] [PUBMED:18362184] [PUBMED:7997267] [PUBMED:8816475] [PUBMED:11279163] [PUBMED:7537852] [PUBMED:11418135] [PUBMED:12167697] [PUBMED:12615911] [PUBMED:12876277]
Syndecan-2-mediated signaling events [NCBI:138031] [Pathway Interaction Database:syndecan_2_pathway] [PUBMED:17623663] [PUBMED:11373281] [PUBMED:16357320] [PUBMED:12507425] [PUBMED:16945929] [PUBMED:14976204] [PUBMED:10772816] [PUBMED:10843988] [PUBMED:8528141] [PUBMED:15936998] [PUBMED:10734053] [PUBMED:11179419] [PUBMED:9660868] [PUBMED:16198615] [PUBMED:9660869] [PUBMED:15752734] [PUBMED:10446183] [PUBMED:11580899] [PUBMED:17548511] [PUBMED:11931647] [PUBMED:16139226] [PUBMED:16008343] [PUBMED:14527339] [PUBMED:16997272] [PUBMED:10639336] [PUBMED:16440330] [PUBMED:11018053] [PUBMED:10704377] [PUBMED:9244383] [PUBMED:12860416]
Syndecan-4-mediated signaling events [NCBI:138064] [Pathway Interaction Database:syndecan_4_pathway] [PUBMED:16604063] [PUBMED:8621465] [PUBMED:17485492] [PUBMED:10633082] [PUBMED:14580209] [PUBMED:14670076] [PUBMED:16357320] [PUBMED:11373281] [PUBMED:11805099] [PUBMED:12087088] [PUBMED:16087677] [PUBMED:8589452] [PUBMED:17901052] [PUBMED:12571249] [PUBMED:16310216] [PUBMED:15694365] [PUBMED:17130131] [PUBMED:17879962] [PUBMED:8609172] [PUBMED:12493766] [PUBMED:10640397] [PUBMED:15819887] [PUBMED:10625452] [PUBMED:9582338] [PUBMED:14637022] [PUBMED:12509413] [PUBMED:16141413] [PUBMED:10734086] [PUBMED:10911369]
VEGFR3 signaling in lymphatic endothelium [NCBI:137996] [Pathway Interaction Database:lymphangiogenesis_pathway] [PUBMED:12881528] [PUBMED:8617204] [PUBMED:10449752] [PUBMED:9247316] [PUBMED:11335727] [PUBMED:9012504] [PUBMED:9435229] [PUBMED:16076871] [PUBMED:11532940] [PUBMED:9927207] [PUBMED:11553610] [PUBMED:7675451] [PUBMED:8662748] [PUBMED:16633338]