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Genes
ITGA5
Gene - ITGA5
full name
integrin subunit alpha 5
synonyms
CD49e, FNRA, VLA5A, ITGA5, ENSG00000161638
HGNC
HGNC:6141
Entrez Gene
Gene:3678
ENSEMBL
ENSG00000161638
location
chr: 12
start: 54789045
stop: 54813050
strand: -
transcripts
ENST00000293379.4
pathways
Angiopoietin receptor Tie2-mediated signaling
[NCBI:137917]
[Pathway Interaction Database:angiopoietinreceptor_pathway]
[PUBMED:9204896]
[PUBMED:12609966]
[PUBMED:14726409]
[PUBMED:11157678]
[PUBMED:10347092]
[PUBMED:11967990]
[PUBMED:15162796]
[PUBMED:11289054]
[PUBMED:12759249]
[PUBMED:10051567]
[PUBMED:12824293]
[PUBMED:16895971]
[PUBMED:10807867]
[PUBMED:12933576]
[PUBMED:11513602]
[PUBMED:12074640]
[PUBMED:8980223]
[PUBMED:14665640]
[PUBMED:15132996]
[PUBMED:10944458]
[PUBMED:11230987]
[PUBMED:15242771]
[PUBMED:10585289]
[PUBMED:16061664]
[PUBMED:10376602]
[PUBMED:15350545]
[PUBMED:9632797]
[PUBMED:10625301]
[PUBMED:9926914]
[PUBMED:17189382]
[PUBMED:11139469]
[PUBMED:11689432]
[PUBMED:11416142]
[PUBMED:11166279]
[PUBMED:15284220]
[PUBMED:15985432]
[PUBMED:16049136]
[PUBMED:16157706]
[PUBMED:10521483]
[PUBMED:12816861]
[PUBMED:9478921]
[PUBMED:10376603]
[PUBMED:15769741]
[PUBMED:12890486]
[PUBMED:14749497]
[PUBMED:7561682]
[PUBMED:11801735]
[PUBMED:12665569]
[PUBMED:12117724]
[PUBMED:9764820]
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
[NCBI:117293]
[KEGG:hsa05412]
[PUBMED:16823481]
[PUBMED:19205777]
[PUBMED:11716909]
[PUBMED:12270949]
[PUBMED:18382419]
[PUBMED:16101641]
[PUBMED:16124859]
[PUBMED:17413274]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Bacterial invasion of epithelial cells
[NCBI:149807]
[KEGG:hsa05100]
[PUBMED:17298394]
[PUBMED:16406780]
[PUBMED:19185531]
[PUBMED:19157959]
[PUBMED:17719540]
[PUBMED:19296488]
Cell surface interactions at the vascular wall
[NCBI:1269373]
[REACTOME:R-HSA-202733]
[PUBMED:17525755]
[PUBMED:11282294]
[PUBMED:10798271]
[PUBMED:8578462]
[PUBMED:14615387]
[PUBMED:16115029]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Dilated cardiomyopathy
[NCBI:121494]
[KEGG:hsa05414]
[PUBMED:11524405]
[PUBMED:11805847]
[PUBMED:12270949]
[PUBMED:14522402]
[PUBMED:19017683]
[PUBMED:15146239]
[PUBMED:18672201]
[PUBMED:19273156]
[PUBMED:19246813]
[PUBMED:11716909]
[PUBMED:16817756]
ECM-receptor interaction
[NCBI:83068]
[KEGG:hsa04512]
[PUBMED:7698997]
[PUBMED:15381249]
[PUBMED:12796473]
[PUBMED:11331578]
[PUBMED:15036264]
[PUBMED:12125070]
[PUBMED:12736199]
[PUBMED:15229478]
[PUBMED:11572082]
[PUBMED:10617638]
[PUBMED:12845610]
[PUBMED:12921709]
Elastic fibre formation
[NCBI:1270251]
[REACTOME:R-HSA-1566948]
[PUBMED:16261592]
Extracellular matrix organization
[NCBI:1270244]
[REACTOME:R-HSA-1474244]
[PUBMED:21123617]
[PUBMED:21917992]
[PUBMED:12845610]
Fibronectin matrix formation
[NCBI:1270250]
[REACTOME:R-HSA-1566977]
[PUBMED:20690820]
Focal adhesion
[NCBI:83067]
[KEGG:hsa04510]
[PUBMED:10698680]
[PUBMED:15459662]
[PUBMED:14756624]
[PUBMED:11573199]
[PUBMED:12640026]
[PUBMED:15179030]
[PUBMED:15108811]
[PUBMED:15053919]
[PUBMED:11082269]
[PUBMED:15034601]
[PUBMED:12235283]
[PUBMED:14519391]
[PUBMED:11146675]
[PUBMED:11229600]
[PUBMED:15688067]
[PUBMED:14744429]
[PUBMED:11882383]
Hematopoietic cell lineage
[NCBI:83078]
[KEGG:hsa04640]
[PUBMED:15629410]
[PUBMED:15738953]
[PUBMED:11905810]
[PUBMED:15156179]
[PUBMED:12415312]
[PUBMED:14985712]
[PUBMED:9927518]
[PUBMED:15771582]
[PUBMED:14670296]
[PUBMED:12360214]
Hemostasis
[NCBI:1269340]
[REACTOME:R-HSA-109582]
Hypertrophic cardiomyopathy (HCM)
[NCBI:114229]
[KEGG:hsa05410]
[PUBMED:11805847]
[PUBMED:18572189]
[PUBMED:14711353]
[PUBMED:19136482]
[PUBMED:18056765]
[PUBMED:11225594]
[PUBMED:12844200]
[PUBMED:10615904]
[PUBMED:11716909]
[PUBMED:11371514]
[PUBMED:12270949]
Integrin cell surface interactions
[NCBI:1270260]
[REACTOME:R-HSA-216083]
[PUBMED:10215583]
[PUBMED:15147720]
[PUBMED:12231361]
[PUBMED:8866399]
[PUBMED:19273203]
L1CAM interactions
[NCBI:1270323]
[REACTOME:R-HSA-373760]
[PUBMED:9211984]
[PUBMED:18760361]
[PUBMED:14709786]
[PUBMED:17189949]
[PUBMED:19356150]
MicroRNAs in cancer
[NCBI:852705]
[KEGG:hsa05206]
[PUBMED:23075324]
[PUBMED:21742789]
[PUBMED:22351564]
[PUBMED:18817506]
[PUBMED:22345301]
[PUBMED:21402473]
[PUBMED:22926415]
[PUBMED:23165235]
[PUBMED:19630570]
[PUBMED:21565290]
[PUBMED:23091478]
[PUBMED:23462054]
[PUBMED:23316212]
[PUBMED:19773200]
[PUBMED:22035854]
[PUBMED:20221895]
[PUBMED:20345848]
[PUBMED:22580099]
[PUBMED:20128019]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Pertussis
[NCBI:218111]
[KEGG:hsa05133]
[PUBMED:20610650]
[PUBMED:12701623]
[PUBMED:15201703]
[PUBMED:18401006]
[PUBMED:20210554]
[PUBMED:16622221]
[PUBMED:17148436]
[PUBMED:21204863]
[PUBMED:20404851]
[PUBMED:10540218]
[PUBMED:16999837]
[PUBMED:16481212]
[PUBMED:16863919]
[PUBMED:16390441]
[PUBMED:21423776]
[PUBMED:17328678]
[PUBMED:12915094]
Phagosome
[NCBI:153910]
[KEGG:hsa04145]
[PUBMED:17637737]
[PUBMED:18513324]
[PUBMED:15894272]
[PUBMED:10684585]
[PUBMED:18492791]
[PUBMED:15036145]
[PUBMED:17245426]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
Regulation of actin cytoskeleton
[NCBI:83089]
[KEGG:hsa04810]
[PUBMED:11152757]
[PUBMED:11082272]
[PUBMED:10574699]
[PUBMED:11082269]
[PUBMED:14657486]
[PUBMED:14744429]
[PUBMED:12700767]
Shigellosis
[NCBI:83104]
[KEGG:hsa05131]
[PUBMED:11379633]
[PUBMED:10491394]
[PUBMED:17173036]
[PUBMED:18202440]
[PUBMED:17095701]
[PUBMED:16622194]
[PUBMED:16413487]
[PUBMED:18005683]
[PUBMED:15731041]
[PUBMED:15073367]
[PUBMED:12856283]
[PUBMED:16939534]
[PUBMED:17060328]
[PUBMED:12065406]
[PUBMED:8376337]
[PUBMED:11207560]
[PUBMED:8642302]
[PUBMED:12356723]
[PUBMED:15694852]
[PUBMED:10369666]
[PUBMED:14638419]
[PUBMED:16441429]
[PUBMED:16162672]
[PUBMED:17719540]
[PUBMED:7665485]
[PUBMED:18059288]
[PUBMED:18005697]
[PUBMED:19165331]
[PUBMED:12828640]
[PUBMED:17662586]
[PUBMED:9176079]
[PUBMED:7591128]
[PUBMED:15318166]
[PUBMED:15950937]
Signal transduction by L1
[NCBI:1270326]
[REACTOME:R-HSA-445144]
[PUBMED:15597056]
[PUBMED:12721290]
[PUBMED:10608864]
[PUBMED:17189949]
[PUBMED:16597699]
[PUBMED:10818153]
Signaling events mediated by focal adhesion kinase
[NCBI:169348]
[Pathway Interaction Database:fak_pathway]
[PUBMED:18793427]
[PUBMED:15340073]
[PUBMED:16054026]
[PUBMED:12932330]
[PUBMED:20038548]
[PUBMED:7542255]
[PUBMED:8939916]
[PUBMED:16000375]
[PUBMED:10856236]
[PUBMED:17164291]
[PUBMED:9148935]
[PUBMED:10893408]
[PUBMED:10512882]
[PUBMED:11839772]
[PUBMED:11553710]
[PUBMED:7566154]
[PUBMED:20018869]
[PUBMED:12839996]
[PUBMED:11799111]
[PUBMED:16308318]
[PUBMED:11331870]
[PUBMED:12681445]
[PUBMED:11369769]
[PUBMED:11739801]
[PUBMED:9860979]
[PUBMED:8947559]
[PUBMED:11017882]
[PUBMED:7509446]
[PUBMED:10791986]
[PUBMED:9128257]
[PUBMED:19297531]
[PUBMED:17325207]
[PUBMED:17093062]
[PUBMED:10593973]
[PUBMED:20308429]
[PUBMED:8922390]
[PUBMED:19776348]
[PUBMED:9374537]
[PUBMED:10976102]
[PUBMED:10373530]
[PUBMED:19883375]
[PUBMED:10430888]
[PUBMED:12820964]
[PUBMED:9425168]
[PUBMED:14743221]
[PUBMED:18854312]
[PUBMED:12952943]
[PUBMED:15962308]
[PUBMED:11927607]
[PUBMED:15657076]
[PUBMED:15039571]
[PUBMED:18303050]
[PUBMED:11799401]
[PUBMED:15247219]
[PUBMED:12702722]
[PUBMED:10998418]
[PUBMED:7615549]
[PUBMED:18195107]
[PUBMED:9032297]
[PUBMED:10873807]
[PUBMED:10777511]
[PUBMED:12502711]
[PUBMED:9566877]
[PUBMED:8649427]
[PUBMED:19473962]
[PUBMED:9808620]
[PUBMED:15914540]
[PUBMED:1385445]
[PUBMED:18223254]
[PUBMED:11909938]
[PUBMED:15166238]
[PUBMED:7622520]
[PUBMED:8824286]
[PUBMED:8662921]
[PUBMED:8707856]
[PUBMED:10330411]
[PUBMED:10446223]
[PUBMED:20150423]
[PUBMED:11604500]
[PUBMED:9234699]
[PUBMED:18773890]
[PUBMED:18757826]
[PUBMED:9864370]
[PUBMED:7983066]
[PUBMED:18322799]
[PUBMED:12006652]
[PUBMED:16461767]
[PUBMED:10385525]
[PUBMED:14676198]
[PUBMED:9858476]
[PUBMED:18070912]
[PUBMED:11058585]
[PUBMED:12890755]
[PUBMED:9184223]
[PUBMED:12058076]
[PUBMED:12226752]
[PUBMED:19435801]
[PUBMED:10212207]
[PUBMED:10521463]
[PUBMED:16159962]
[PUBMED:7579684]
[PUBMED:18362184]
[PUBMED:7997267]
[PUBMED:8816475]
[PUBMED:11279163]
[PUBMED:7537852]
[PUBMED:11418135]
[PUBMED:12167697]
[PUBMED:12615911]
[PUBMED:12876277]
Syndecan-2-mediated signaling events
[NCBI:138031]
[Pathway Interaction Database:syndecan_2_pathway]
[PUBMED:17623663]
[PUBMED:11373281]
[PUBMED:16357320]
[PUBMED:12507425]
[PUBMED:16945929]
[PUBMED:14976204]
[PUBMED:10772816]
[PUBMED:10843988]
[PUBMED:8528141]
[PUBMED:15936998]
[PUBMED:10734053]
[PUBMED:11179419]
[PUBMED:9660868]
[PUBMED:16198615]
[PUBMED:9660869]
[PUBMED:15752734]
[PUBMED:10446183]
[PUBMED:11580899]
[PUBMED:17548511]
[PUBMED:11931647]
[PUBMED:16139226]
[PUBMED:16008343]
[PUBMED:14527339]
[PUBMED:16997272]
[PUBMED:10639336]
[PUBMED:16440330]
[PUBMED:11018053]
[PUBMED:10704377]
[PUBMED:9244383]
[PUBMED:12860416]
Syndecan-4-mediated signaling events
[NCBI:138064]
[Pathway Interaction Database:syndecan_4_pathway]
[PUBMED:16604063]
[PUBMED:8621465]
[PUBMED:17485492]
[PUBMED:10633082]
[PUBMED:14580209]
[PUBMED:14670076]
[PUBMED:16357320]
[PUBMED:11373281]
[PUBMED:11805099]
[PUBMED:12087088]
[PUBMED:16087677]
[PUBMED:8589452]
[PUBMED:17901052]
[PUBMED:12571249]
[PUBMED:16310216]
[PUBMED:15694365]
[PUBMED:17130131]
[PUBMED:17879962]
[PUBMED:8609172]
[PUBMED:12493766]
[PUBMED:10640397]
[PUBMED:15819887]
[PUBMED:10625452]
[PUBMED:9582338]
[PUBMED:14637022]
[PUBMED:12509413]
[PUBMED:16141413]
[PUBMED:10734086]
[PUBMED:10911369]
VEGFR3 signaling in lymphatic endothelium
[NCBI:137996]
[Pathway Interaction Database:lymphangiogenesis_pathway]
[PUBMED:12881528]
[PUBMED:8617204]
[PUBMED:10449752]
[PUBMED:9247316]
[PUBMED:11335727]
[PUBMED:9012504]
[PUBMED:9435229]
[PUBMED:16076871]
[PUBMED:11532940]
[PUBMED:9927207]
[PUBMED:11553610]
[PUBMED:7675451]
[PUBMED:8662748]
[PUBMED:16633338]