full name
phosphodiesterase 1B

synonyms
PDE1B1, PDES1B, PDE1B, ENSG00000123360

HGNC
HGNC:8775

Entrez Gene
Gene:5153

ENSEMBL
ENSG00000123360

location
chr: 12
start: 54943177
stop: 54973023
strand: +

transcripts
NM_000924.3
NM_001165975.2

pathways
Ca-dependent events [NCBI:1269588] [REACTOME:R-HSA-111996] [PUBMED:18083096] [PUBMED:11162741] [PUBMED:17697045] [PUBMED:16076488]
CaM pathway [NCBI:1269292] [REACTOME:R-HSA-111997] [PUBMED:10884684]
Calcium signaling pathway [NCBI:83050] [KEGG:hsa04020] [PUBMED:11080247] [PUBMED:14572802] [PUBMED:11413485] [PUBMED:22129055] [PUBMED:10508738] [PUBMED:15000521] [PUBMED:9235901] [PUBMED:7861177] [PUBMED:9149541] [PUBMED:14517314] [PUBMED:15111104] [PUBMED:11698232] [PUBMED:10331643] [PUBMED:12838335] [PUBMED:8125957] [PUBMED:19172794] [PUBMED:10997573] [PUBMED:21338471] [PUBMED:11299192] [PUBMED:22002090] [PUBMED:12972622]
Calmodulin induced events [NCBI:1269293] [REACTOME:R-HSA-111933] [PUBMED:15381755]
Cam-PDE 1 activation [NCBI:1269297] [REACTOME:R-HSA-111957] [PUBMED:16786160] [PUBMED:10442095]
DAG and IP3 signaling [NCBI:1269291] [REACTOME:R-HSA-1489509] [PUBMED:16260143]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
EGFR interacts with phospholipase C-gamma [NCBI:1269381] [REACTOME:R-HSA-212718] [PUBMED:1501243]
G alpha (s) signalling events [NCBI:1269575] [REACTOME:R-HSA-418555] [PUBMED:12036966]
G-protein mediated events [NCBI:1269586] [REACTOME:R-HSA-112040] [PUBMED:9422713] [PUBMED:9218123]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Morphine addiction [NCBI:552665] [KEGG:hsa05032] [PUBMED:8785060] [PUBMED:16581089] [PUBMED:21872647] [PUBMED:14625081] [PUBMED:20962224] [PUBMED:15661627] [PUBMED:1346804] [PUBMED:12859419] [PUBMED:8096779] [PUBMED:18349442] [PUBMED:21930931] [PUBMED:10066284] [PUBMED:14969742] [PUBMED:8987801] [PUBMED:12217944] [PUBMED:11750924] [PUBMED:11152760]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Nitric oxide stimulates guanylate cyclase [NCBI:1269343] [REACTOME:R-HSA-392154] [PUBMED:12881475]
Olfactory transduction [NCBI:83087] [KEGG:hsa04740] [PUBMED:19652915] [PUBMED:22735517] [PUBMED:11557990] [PUBMED:19306880] [PUBMED:16269360] [PUBMED:19941039] [PUBMED:20145624] [PUBMED:12488531] [PUBMED:22875451] [PUBMED:24733839] [PUBMED:10944513]
Opioid Signalling [NCBI:1269584] [REACTOME:R-HSA-111885] [PUBMED:9422713] [PUBMED:9218123] [PUBMED:16612131]
PLC beta mediated events [NCBI:1269587] [REACTOME:R-HSA-112043] [PUBMED:9218123] [PUBMED:16183910] [PUBMED:1335363]
PLC-gamma1 signalling [NCBI:1269472] [REACTOME:R-HSA-167021] [PUBMED:12676795] [PUBMED:10579907]
Platelet homeostasis [NCBI:1269341] [REACTOME:R-HSA-418346] [PUBMED:10798271]
Purine metabolism [NCBI:82944] [KEGG:hsa00230] [NCBI:1270134] [REACTOME:R-HSA-73847] [PUBMED:4620886] [PUBMED:10986234] [PUBMED:10601204]
Renin secretion [NCBI:1222951] [KEGG:hsa04924] [PUBMED:24944035] [PUBMED:22733355] [PUBMED:20936939] [PUBMED:12949225] [PUBMED:17360952] [PUBMED:17928544] [PUBMED:19948673] [PUBMED:12388321] [PUBMED:15283749] [PUBMED:22237158] [PUBMED:22258323] [PUBMED:9882634] [PUBMED:20393195] [PUBMED:22124804]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
Taste transduction [NCBI:83088] [KEGG:hsa04742] [PUBMED:14715493] [PUBMED:17108952] [PUBMED:21481196] [PUBMED:20696704] [PUBMED:19439032] [PUBMED:24607224] [PUBMED:23261954] [PUBMED:25820328] [PUBMED:23587289] [PUBMED:23467090] [PUBMED:22570381] [PUBMED:19284629] [PUBMED:23959882] [PUBMED:17287577] [PUBMED:24385952]
cGMP effects [NCBI:1269344] [REACTOME:R-HSA-418457] [PUBMED:7913615] [PUBMED:14597579]