full name
prostaglandin E synthase 3

synonyms
cPGES, P23, TEBP, PTGES3, ENSG00000110958

HGNC
HGNC:16049

Entrez Gene
Gene:10728

ENSEMBL
ENSG00000110958

location
chr: 12
start: 57057125
stop: 57082138
strand: -

transcripts
NM_006601.5

pathways
Arachidonic acid metabolism [NCBI:82991] [KEGG:hsa00590] [NCBI:1270087] [REACTOME:R-HSA-2142753] [PUBMED:14622984] [PUBMED:15292194] [PUBMED:10908295] [PUBMED:15205388] [PUBMED:9812980] [PUBMED:14660610] [PUBMED:11328810] [PUBMED:14636671] [PUBMED:14626496] [PUBMED:11679404] [PUBMED:19244215]
Aryl hydrocarbon receptor signalling [NCBI:1470921] [REACTOME:R-HSA-8937144] [PUBMED:16972786] [PUBMED:18540824] [PUBMED:18848529]
Attenuation phase [NCBI:1270424] [REACTOME:R-HSA-3371568] [PUBMED:1936996]
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
C20 prostanoid biosynthesis [NCBI:545299] [BIOCYC:HUMAN_PWY66-374] [PUBMED:2107175] [PUBMED:11729303]
Cellular response to heat stress [NCBI:1270421] [REACTOME:R-HSA-3371556] [PUBMED:8455624] [PUBMED:8441385]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
HSF1 activation [NCBI:1270422] [REACTOME:R-HSA-3371511] [PUBMED:7623826] [PUBMED:8631933]
HSF1-dependent transactivation [NCBI:1270423] [REACTOME:R-HSA-3371571] [PUBMED:7623826]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]
Regulation of Telomerase [NCBI:137987] [Pathway Interaction Database:telomerasepathway] [PUBMED:12037663] [PUBMED:11191110] [PUBMED:15381700] [PUBMED:10637317] [PUBMED:15314656] [PUBMED:10601322] [PUBMED:12545159] [PUBMED:11110707] [PUBMED:15371341] [PUBMED:12681489] [PUBMED:15824061] [PUBMED:15048073] [PUBMED:10850490] [PUBMED:16730176] [PUBMED:12181313] [PUBMED:16890531] [PUBMED:9837921] [PUBMED:10224060] [PUBMED:15331176] [PUBMED:16522649] [PUBMED:9822378] [PUBMED:15316005] [PUBMED:12699629] [PUBMED:16843438] [PUBMED:12151407] [PUBMED:12135483] [PUBMED:15655249] [PUBMED:10888888] [PUBMED:16765199] [PUBMED:16869756] [PUBMED:10837221] [PUBMED:16135795] [PUBMED:11074006] [PUBMED:11191109] [PUBMED:14712220] [PUBMED:16508638] [PUBMED:10471503] [PUBMED:11854288] [PUBMED:16785237] [PUBMED:9130722] [PUBMED:12956959] [PUBMED:15710386] [PUBMED:12586360] [PUBMED:12377759] [PUBMED:11433024] [PUBMED:15843522] [PUBMED:14749375] [PUBMED:11274138] [PUBMED:12676087] [PUBMED:16166375] [PUBMED:15371412]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) [NCBI:1270088] [REACTOME:R-HSA-2162123] [PUBMED:20655950] [PUBMED:19244215]