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Genes
PRIM1
Gene - PRIM1
full name
primase (DNA) subunit 1
synonyms
p49, PRIM1, ENSG00000198056
HGNC
HGNC:9369
Entrez Gene
Gene:5557
ENSEMBL
ENSG00000198056
location
chr: 12
start: 57125364
stop: 57146146
strand: -
transcripts
NM_000946.2
pathways
Activation of the pre-replicative complex
[NCBI:1269773]
[REACTOME:R-HSA-68962]
[PUBMED:10402192]
[PUBMED:11779870]
[PUBMED:10801458]
[PUBMED:12169736]
[PUBMED:11323433]
[PUBMED:9038340]
[PUBMED:9765232]
[PUBMED:9829972]
[PUBMED:10970868]
[PUBMED:9353276]
[PUBMED:7502077]
[PUBMED:11459976]
[PUBMED:11395502]
Cell Cycle
[NCBI:1269741]
[REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic
[NCBI:1269763]
[REACTOME:R-HSA-69278]
Chromosome Maintenance
[NCBI:1269853]
[REACTOME:R-HSA-73886]
DNA Replication
[NCBI:1269875]
[REACTOME:R-HSA-69306]
[PUBMED:11257218]
[PUBMED:12045100]
[PUBMED:1536007]
[PUBMED:10966477]
[PUBMED:1579437]
[PUBMED:8223461]
DNA Replication Pre-Initiation
[NCBI:1269832]
[REACTOME:R-HSA-69002]
DNA replication
[NCBI:83039]
[KEGG:hsa03030]
[PUBMED:9759502]
[PUBMED:8087839]
DNA replication initiation
[NCBI:1269780]
[REACTOME:R-HSA-68952]
[PUBMED:6693436]
[PUBMED:11395402]
DNA strand elongation
[NCBI:1269784]
[REACTOME:R-HSA-69190]
[PUBMED:9081985]
[PUBMED:1976634]
[PUBMED:7623835]
[PUBMED:1536007]
[PUBMED:8594377]
E2F mediated regulation of DNA replication
[NCBI:1269774]
[REACTOME:R-HSA-113510]
[PUBMED:12393009]
[PUBMED:12726857]
[PUBMED:12473340]
Extension of Telomeres
[NCBI:1269857]
[REACTOME:R-HSA-180786]
[PUBMED:15189140]
G1/S Transition
[NCBI:1269768]
[REACTOME:R-HSA-69206]
Inhibition of replication initiation of damaged DNA by RB1/E2F1
[NCBI:1269775]
[REACTOME:R-HSA-113501]
Lagging Strand Synthesis
[NCBI:1269788]
[REACTOME:R-HSA-69186]
[PUBMED:9081985]
Leading Strand Synthesis
[NCBI:1269786]
[REACTOME:R-HSA-69109]
[PUBMED:2175912]
[PUBMED:7378348]
[PUBMED:9191022]
M/G1 Transition
[NCBI:1269831]
[REACTOME:R-HSA-68874]
Metabolic pathways
[NCBI:132956]
[KEGG:hsa01100]
Mitotic G1-G1/S phases
[NCBI:1269764]
[REACTOME:R-HSA-453279]
Polymerase switching
[NCBI:1269787]
[REACTOME:R-HSA-69091]
[PUBMED:1967833]
[PUBMED:1671046]
[PUBMED:1670772]
Polymerase switching on the C-strand of the telomere
[NCBI:1269861]
[REACTOME:R-HSA-174411]
[PUBMED:1967833]
[PUBMED:1671046]
[PUBMED:1670772]
Processive synthesis on the lagging strand
[NCBI:1269789]
[REACTOME:R-HSA-69183]
[PUBMED:1671046]
Purine metabolism
[NCBI:82944]
[KEGG:hsa00230]
[NCBI:1270134]
[REACTOME:R-HSA-73847]
[PUBMED:4620886]
[PUBMED:10986234]
[PUBMED:10601204]
Pyrimidine metabolism
[NCBI:82946]
[KEGG:hsa00240]
[NCBI:1270138]
[REACTOME:R-HSA-73848]
[PUBMED:16098809]
Removal of the Flap Intermediate
[NCBI:1269790]
[REACTOME:R-HSA-69166]
[PUBMED:7926735]
[PUBMED:8131753]
[PUBMED:7644470]
S Phase
[NCBI:1269777]
[REACTOME:R-HSA-69242]
Synthesis of DNA
[NCBI:1269779]
[REACTOME:R-HSA-69239]
Telomere C-strand (Lagging Strand) Synthesis
[NCBI:1269859]
[REACTOME:R-HSA-174417]
[PUBMED:15189140]
Telomere C-strand synthesis initiation
[NCBI:1269860]
[REACTOME:R-HSA-174430]
[PUBMED:11327863]
[PUBMED:11395402]
[PUBMED:6693436]
Telomere Maintenance
[NCBI:1269856]
[REACTOME:R-HSA-157579]
[PUBMED:16166375]
[PUBMED:4507727]
[PUBMED:14685173]
[PUBMED:642006]
[PUBMED:15189140]
[PUBMED:3907856]
[PUBMED:2463488]
[PUBMED:4754905]