full name
primase (DNA) subunit 1

synonyms
p49, PRIM1, ENSG00000198056

HGNC
HGNC:9369

Entrez Gene
Gene:5557

ENSEMBL
ENSG00000198056

location
chr: 12
start: 57125364
stop: 57146146
strand: -

transcripts
NM_000946.2

pathways
Activation of the pre-replicative complex [NCBI:1269773] [REACTOME:R-HSA-68962] [PUBMED:10402192] [PUBMED:11779870] [PUBMED:10801458] [PUBMED:12169736] [PUBMED:11323433] [PUBMED:9038340] [PUBMED:9765232] [PUBMED:9829972] [PUBMED:10970868] [PUBMED:9353276] [PUBMED:7502077] [PUBMED:11459976] [PUBMED:11395502]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Chromosome Maintenance [NCBI:1269853] [REACTOME:R-HSA-73886]
DNA Replication [NCBI:1269875] [REACTOME:R-HSA-69306] [PUBMED:11257218] [PUBMED:12045100] [PUBMED:1536007] [PUBMED:10966477] [PUBMED:1579437] [PUBMED:8223461]
DNA Replication Pre-Initiation [NCBI:1269832] [REACTOME:R-HSA-69002]
DNA replication [NCBI:83039] [KEGG:hsa03030] [PUBMED:9759502] [PUBMED:8087839]
DNA replication initiation [NCBI:1269780] [REACTOME:R-HSA-68952] [PUBMED:6693436] [PUBMED:11395402]
DNA strand elongation [NCBI:1269784] [REACTOME:R-HSA-69190] [PUBMED:9081985] [PUBMED:1976634] [PUBMED:7623835] [PUBMED:1536007] [PUBMED:8594377]
E2F mediated regulation of DNA replication [NCBI:1269774] [REACTOME:R-HSA-113510] [PUBMED:12393009] [PUBMED:12726857] [PUBMED:12473340]
Extension of Telomeres [NCBI:1269857] [REACTOME:R-HSA-180786] [PUBMED:15189140]
G1/S Transition [NCBI:1269768] [REACTOME:R-HSA-69206]
Inhibition of replication initiation of damaged DNA by RB1/E2F1 [NCBI:1269775] [REACTOME:R-HSA-113501]
Lagging Strand Synthesis [NCBI:1269788] [REACTOME:R-HSA-69186] [PUBMED:9081985]
Leading Strand Synthesis [NCBI:1269786] [REACTOME:R-HSA-69109] [PUBMED:2175912] [PUBMED:7378348] [PUBMED:9191022]
M/G1 Transition [NCBI:1269831] [REACTOME:R-HSA-68874]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Mitotic G1-G1/S phases [NCBI:1269764] [REACTOME:R-HSA-453279]
Polymerase switching [NCBI:1269787] [REACTOME:R-HSA-69091] [PUBMED:1967833] [PUBMED:1671046] [PUBMED:1670772]
Polymerase switching on the C-strand of the telomere [NCBI:1269861] [REACTOME:R-HSA-174411] [PUBMED:1967833] [PUBMED:1671046] [PUBMED:1670772]
Processive synthesis on the lagging strand [NCBI:1269789] [REACTOME:R-HSA-69183] [PUBMED:1671046]
Purine metabolism [NCBI:82944] [KEGG:hsa00230] [NCBI:1270134] [REACTOME:R-HSA-73847] [PUBMED:4620886] [PUBMED:10986234] [PUBMED:10601204]
Pyrimidine metabolism [NCBI:82946] [KEGG:hsa00240] [NCBI:1270138] [REACTOME:R-HSA-73848] [PUBMED:16098809]
Removal of the Flap Intermediate [NCBI:1269790] [REACTOME:R-HSA-69166] [PUBMED:7926735] [PUBMED:8131753] [PUBMED:7644470]
S Phase [NCBI:1269777] [REACTOME:R-HSA-69242]
Synthesis of DNA [NCBI:1269779] [REACTOME:R-HSA-69239]
Telomere C-strand (Lagging Strand) Synthesis [NCBI:1269859] [REACTOME:R-HSA-174417] [PUBMED:15189140]
Telomere C-strand synthesis initiation [NCBI:1269860] [REACTOME:R-HSA-174430] [PUBMED:11327863] [PUBMED:11395402] [PUBMED:6693436]
Telomere Maintenance [NCBI:1269856] [REACTOME:R-HSA-157579] [PUBMED:16166375] [PUBMED:4507727] [PUBMED:14685173] [PUBMED:642006] [PUBMED:15189140] [PUBMED:3907856] [PUBMED:2463488] [PUBMED:4754905]