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Genes
STAT6
Gene - STAT6
full name
signal transducer and activator of transcription 6
synonyms
D12S1644, IL-4-STAT, STAT6B, STAT6C, STAT6, ENSG00000166888
HGNC
HGNC:11368
Entrez Gene
Gene:6778
ENSEMBL
ENSG00000166888
location
chr: 12
start: 57489187
stop: 57505196
strand: -
transcripts
NM_001178081.1
NM_001178080.1
NR_033659.1
NM_003153.4
NM_001178078.1
NM_001178079.1
pathways
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Cytosolic sensors of pathogen-associated DNA
[NCBI:1269268]
[REACTOME:R-HSA-1834949]
[PUBMED:23706668]
[PUBMED:21533068]
[PUBMED:23706667]
Downstream signal transduction
[NCBI:1269479]
[REACTOME:R-HSA-186763]
[PUBMED:10508235]
[PUBMED:9739761]
Hepatitis B
[NCBI:694606]
[KEGG:hsa05161]
[PUBMED:19854353]
[PUBMED:11604508]
[PUBMED:11325602]
[PUBMED:18931690]
[PUBMED:16891440]
[PUBMED:17158882]
[PUBMED:11099494]
[PUBMED:9325306]
[PUBMED:18024894]
[PUBMED:11483993]
[PUBMED:15107488]
[PUBMED:11278872]
[PUBMED:21647825]
[PUBMED:11287574]
[PUBMED:18481805]
[PUBMED:17188775]
[PUBMED:19784739]
[PUBMED:19263472]
[PUBMED:16203685]
[PUBMED:18605975]
[PUBMED:10454581]
[PUBMED:22504921]
[PUBMED:21334391]
[PUBMED:20657822]
[PUBMED:18046710]
[PUBMED:9843511]
[PUBMED:15542625]
[PUBMED:21618535]
[PUBMED:15132991]
[PUBMED:15173177]
[PUBMED:12771941]
[PUBMED:21994545]
[PUBMED:8764004]
[PUBMED:16459163]
[PUBMED:9738022]
[PUBMED:11821950]
[PUBMED:12839924]
IL12-mediated signaling events
[NCBI:137922]
[Pathway Interaction Database:il12_2pathway]
[PUBMED:12874225]
[PUBMED:12221108]
[PUBMED:16380506]
[PUBMED:9768751]
[PUBMED:17114419]
[PUBMED:10358173]
[PUBMED:9890938]
[PUBMED:12213961]
[PUBMED:11120802]
[PUBMED:9202126]
[PUBMED:16641133]
[PUBMED:10198225]
[PUBMED:16763563]
[PUBMED:15728489]
[PUBMED:8103068]
[PUBMED:10903740]
[PUBMED:10201984]
[PUBMED:7638186]
[PUBMED:11894097]
[PUBMED:16220539]
[PUBMED:10961885]
[PUBMED:7594594]
[PUBMED:17110450]
[PUBMED:9582275]
[PUBMED:10320373]
[PUBMED:7528775]
[PUBMED:11207258]
[PUBMED:9038232]
[PUBMED:15522880]
[PUBMED:11175814]
[PUBMED:9531298]
[PUBMED:7722452]
[PUBMED:8943050]
[PUBMED:7553885]
[PUBMED:9454765]
IL4-mediated signaling events
[NCBI:137933]
[Pathway Interaction Database:il4_2pathway]
[PUBMED:8602263]
[PUBMED:15199062]
[PUBMED:7705411]
[PUBMED:11160325]
[PUBMED:8557643]
[PUBMED:8134361]
[PUBMED:1948049]
[PUBMED:10843732]
[PUBMED:11034397]
[PUBMED:8624802]
[PUBMED:14557412]
[PUBMED:1997653]
[PUBMED:10586089]
[PUBMED:14634100]
[PUBMED:17541284]
[PUBMED:8124718]
[PUBMED:16210622]
[PUBMED:7822337]
[PUBMED:11572871]
[PUBMED:2147202]
[PUBMED:10228008]
[PUBMED:7675087]
[PUBMED:12574343]
[PUBMED:14603527]
[PUBMED:15659391]
[PUBMED:11160269]
[PUBMED:7760829]
[PUBMED:7973658]
[PUBMED:10072514]
[PUBMED:9013879]
[PUBMED:8624803]
[PUBMED:10490661]
[PUBMED:14978013]
[PUBMED:10364072]
[PUBMED:12459556]
[PUBMED:11714803]
[PUBMED:8602264]
[PUBMED:9811885]
[PUBMED:12776189]
[PUBMED:15728454]
[PUBMED:10601358]
[PUBMED:11739727]
[PUBMED:11160275]
[PUBMED:9852037]
[PUBMED:9670964]
[PUBMED:15004182]
[PUBMED:8266078]
[PUBMED:3144043]
[PUBMED:8992992]
[PUBMED:8089482]
[PUBMED:9651359]
[PUBMED:16810739]
[PUBMED:7499365]
[PUBMED:7721786]
[PUBMED:9065461]
[PUBMED:11241672]
[PUBMED:10950967]
[PUBMED:8810328]
[PUBMED:8624821]
[PUBMED:9110977]
[PUBMED:8609418]
[PUBMED:15187136]
[PUBMED:9414268]
[PUBMED:8916957]
[PUBMED:10201892]
[PUBMED:17200144]
[PUBMED:8458387]
[PUBMED:11544308]
[PUBMED:10657944]
[PUBMED:15153491]
[PUBMED:7544011]
[PUBMED:8266076]
[PUBMED:11801631]
[PUBMED:12044779]
[PUBMED:8621475]
[PUBMED:9697832]
[PUBMED:12242343]
[PUBMED:7694370]
[PUBMED:9380721]
[PUBMED:9541585]
[PUBMED:7807002]
[PUBMED:16537510]
[PUBMED:8258319]
[PUBMED:9799097]
[PUBMED:12023955]
[PUBMED:8085155]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Inflammatory bowel disease (IBD)
[NCBI:842771]
[KEGG:hsa05321]
[PUBMED:17499605]
[PUBMED:12006974]
[PUBMED:18053739]
[PUBMED:20134493]
[PUBMED:10898785]
[PUBMED:18563156]
[PUBMED:23176791]
[PUBMED:18200661]
[PUBMED:12797537]
[PUBMED:21487504]
[PUBMED:19381306]
[PUBMED:21681604]
[PUBMED:19322214]
[PUBMED:16493424]
[PUBMED:18242222]
[PUBMED:12042806]
[PUBMED:9759857]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Interleukin-4 and 13 signaling
[NCBI:1470923]
[REACTOME:R-HSA-6785807]
[PUBMED:12704343]
[PUBMED:10358772]
Jak-STAT signaling pathway
[NCBI:83077]
[KEGG:hsa04630]
[PUBMED:21034406]
[PUBMED:22339650]
[PUBMED:16204702]
[PUBMED:25587654]
[PUBMED:24069565]
[PUBMED:22383755]
[PUBMED:24606160]
[PUBMED:10851053]
[PUBMED:23735217]
[PUBMED:25217450]
[PUBMED:21372217]
STAT6-mediated induction of chemokines
[NCBI:1269274]
[REACTOME:R-HSA-3249367]
[PUBMED:22000020]
STING mediated induction of host immune responses
[NCBI:1269272]
[REACTOME:R-HSA-1834941]
[PUBMED:19776740]
[PUBMED:22607800]
[PUBMED:18724357]
[PUBMED:21947006]
[PUBMED:22394562]
[PUBMED:23585680]
[PUBMED:23478444]
[PUBMED:19433799]
[PUBMED:20107183]
[PUBMED:21820332]
[PUBMED:20871604]
[PUBMED:19926846]
[PUBMED:21892174]
[PUBMED:22706339]
[PUBMED:20890285]
[PUBMED:23604073]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Signaling by PDGF
[NCBI:1269478]
[REACTOME:R-HSA-186797]
[PUBMED:15207811]
[PUBMED:10508235]
[PUBMED:9739761]
Signaling events mediated by TCPTP
[NCBI:169350]
[Pathway Interaction Database:tcptp_pathway]
[PUBMED:12612081]
[PUBMED:18716132]
[PUBMED:19171783]
[PUBMED:9488479]
[PUBMED:15592458]
[PUBMED:9261175]
[PUBMED:16431927]
[PUBMED:15632081]
[PUBMED:12359225]
[PUBMED:12138178]
[PUBMED:7593185]
[PUBMED:18840653]
[PUBMED:15696169]
[PUBMED:18691551]
[PUBMED:20484139]
[PUBMED:11773439]
[PUBMED:16595549]
[PUBMED:18948751]
[PUBMED:16971512]
[PUBMED:12171910]
[PUBMED:18819921]
[PUBMED:15192089]
[PUBMED:17210636]
[PUBMED:10488121]
[PUBMED:16705167]
[PUBMED:14966296]
[PUBMED:11909529]
[PUBMED:11479308]
Th1 and Th2 cell differentiation
[NCBI:1458885]
[KEGG:hsa04658]
[PUBMED:15819694]
[PUBMED:12171942]
[PUBMED:19165228]
[PUBMED:23336087]
[PUBMED:26044597]
[PUBMED:19151746]
[PUBMED:19362457]
[PUBMED:22044277]
[PUBMED:11752608]
[PUBMED:23405903]
[PUBMED:19375293]
[PUBMED:24113868]
[PUBMED:19151747]
[PUBMED:23624818]
[PUBMED:22566933]
[PUBMED:11121747]
[PUBMED:20969597]
[PUBMED:20065998]
Th17 cell differentiation
[NCBI:1469482]
[KEGG:hsa04659]
[PUBMED:23325835]
[PUBMED:23036716]
[PUBMED:20488727]
[PUBMED:21151104]
[PUBMED:21084214]
[PUBMED:20054607]
[PUBMED:22754770]
[PUBMED:22640807]
[PUBMED:19379825]
[PUBMED:22133865]
[PUBMED:22324470]
[PUBMED:17768419]
[PUBMED:18408735]
[PUBMED:21776333]
[PUBMED:26253381]
[PUBMED:16200068]
[PUBMED:18362914]
[PUBMED:24325586]
[PUBMED:19381306]
[PUBMED:18166487]