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Genes
ARHGEF11
Gene - ARHGEF11
full name
Rho guanine nucleotide exchange factor 11
synonyms
GTRAP48, PDZ-RHOGEF, ARHGEF11, ENSG00000132694
HGNC
HGNC:14580
Entrez Gene
Gene:9826
ENSEMBL
ENSG00000132694
location
chr: 1
start: 156904632
stop: 157015512
strand: -
transcripts
NM_014784.3
NM_198236.2
pathways
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Cell death signalling via NRAGE, NRIF and NADE
[NCBI:1269447]
[REACTOME:R-HSA-204998]
[PUBMED:12787561]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
G alpha (12/13) signalling events
[NCBI:1269579]
[REACTOME:R-HSA-416482]
[PUBMED:18814923]
[PUBMED:19212140]
GPCR downstream signaling
[NCBI:1269574]
[REACTOME:R-HSA-388396]
[PUBMED:12040175]
NRAGE signals death through JNK
[NCBI:1269448]
[REACTOME:R-HSA-193648]
[PUBMED:12376548]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Regulation of RhoA activity
[NCBI:138070]
[Pathway Interaction Database:rhoa_reg_pathway]
[PUBMED:10579713]
[PUBMED:15039571]
[PUBMED:19605563]
[PUBMED:19755152]
[PUBMED:16954208]
[PUBMED:10744696]
[PUBMED:17702745]
[PUBMED:10837491]
[PUBMED:12454018]
[PUBMED:15023524]
[PUBMED:11396949]
[PUBMED:10523675]
[PUBMED:10026210]
[PUBMED:18948007]
[PUBMED:16112081]
[PUBMED:19713215]
[PUBMED:9425278]
[PUBMED:11085924]
[PUBMED:9582072]
[PUBMED:12071859]
[PUBMED:19066281]
[PUBMED:14512443]
[PUBMED:18851832]
[PUBMED:12775584]
[PUBMED:15632174]
[PUBMED:8356058]
[PUBMED:1907371]
[PUBMED:11058585]
[PUBMED:9032261]
[PUBMED:18211802]
[PUBMED:12414125]
[PUBMED:17971419]
[PUBMED:19625450]
[PUBMED:15069594]
[PUBMED:12221096]
[PUBMED:17804252]
[PUBMED:8276860]
[PUBMED:19635168]
[PUBMED:8910315]
[PUBMED:18096806]
[PUBMED:12183458]
[PUBMED:15601624]
[PUBMED:9464532]
[PUBMED:11336673]
[PUBMED:16721066]
[PUBMED:12215546]
[PUBMED:15078817]
[PUBMED:12196628]
[PUBMED:11553710]
[PUBMED:7479768]
[PUBMED:8643598]
[PUBMED:10699171]
[PUBMED:9490638]
[PUBMED:8491184]
[PUBMED:8352776]
[PUBMED:20018869]
[PUBMED:12944407]
[PUBMED:11804590]
[PUBMED:8297393]
[PUBMED:11672528]
[PUBMED:15296756]
[PUBMED:17488622]
[PUBMED:9670022]
[PUBMED:8537347]
[PUBMED:19261619]
[PUBMED:16896804]
[PUBMED:11094164]
[PUBMED:15691829]
[PUBMED:19103606]
[PUBMED:9641916]
Rho GTPase cycle
[NCBI:1269508]
[REACTOME:R-HSA-194840]
[PUBMED:17222083]
[PUBMED:9308960]
Sema4D in semaphorin signaling
[NCBI:1270305]
[REACTOME:R-HSA-400685]
[PUBMED:16314868]
[PUBMED:14770294]
[PUBMED:15818466]
Sema4D induced cell migration and growth-cone collapse
[NCBI:1270307]
[REACTOME:R-HSA-416572]
[PUBMED:12220504]
[PUBMED:18374575]
[PUBMED:15210733]
[PUBMED:15818466]
Semaphorin interactions
[NCBI:1270304]
[REACTOME:R-HSA-373755]
[PUBMED:12593985]
[PUBMED:12471249]
[PUBMED:18269210]
[PUBMED:16939971]
[PUBMED:18374575]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]
Signaling events mediated by focal adhesion kinase
[NCBI:169348]
[Pathway Interaction Database:fak_pathway]
[PUBMED:18793427]
[PUBMED:15340073]
[PUBMED:16054026]
[PUBMED:12932330]
[PUBMED:20038548]
[PUBMED:7542255]
[PUBMED:8939916]
[PUBMED:16000375]
[PUBMED:10856236]
[PUBMED:17164291]
[PUBMED:9148935]
[PUBMED:10893408]
[PUBMED:10512882]
[PUBMED:11839772]
[PUBMED:11553710]
[PUBMED:7566154]
[PUBMED:20018869]
[PUBMED:12839996]
[PUBMED:11799111]
[PUBMED:16308318]
[PUBMED:11331870]
[PUBMED:12681445]
[PUBMED:11369769]
[PUBMED:11739801]
[PUBMED:9860979]
[PUBMED:8947559]
[PUBMED:11017882]
[PUBMED:7509446]
[PUBMED:10791986]
[PUBMED:9128257]
[PUBMED:19297531]
[PUBMED:17325207]
[PUBMED:17093062]
[PUBMED:10593973]
[PUBMED:20308429]
[PUBMED:8922390]
[PUBMED:19776348]
[PUBMED:9374537]
[PUBMED:10976102]
[PUBMED:10373530]
[PUBMED:19883375]
[PUBMED:10430888]
[PUBMED:12820964]
[PUBMED:9425168]
[PUBMED:14743221]
[PUBMED:18854312]
[PUBMED:12952943]
[PUBMED:15962308]
[PUBMED:11927607]
[PUBMED:15657076]
[PUBMED:15039571]
[PUBMED:18303050]
[PUBMED:11799401]
[PUBMED:15247219]
[PUBMED:12702722]
[PUBMED:10998418]
[PUBMED:7615549]
[PUBMED:18195107]
[PUBMED:9032297]
[PUBMED:10873807]
[PUBMED:10777511]
[PUBMED:12502711]
[PUBMED:9566877]
[PUBMED:8649427]
[PUBMED:19473962]
[PUBMED:9808620]
[PUBMED:15914540]
[PUBMED:1385445]
[PUBMED:18223254]
[PUBMED:11909938]
[PUBMED:15166238]
[PUBMED:7622520]
[PUBMED:8824286]
[PUBMED:8662921]
[PUBMED:8707856]
[PUBMED:10330411]
[PUBMED:10446223]
[PUBMED:20150423]
[PUBMED:11604500]
[PUBMED:9234699]
[PUBMED:18773890]
[PUBMED:18757826]
[PUBMED:9864370]
[PUBMED:7983066]
[PUBMED:18322799]
[PUBMED:12006652]
[PUBMED:16461767]
[PUBMED:10385525]
[PUBMED:14676198]
[PUBMED:9858476]
[PUBMED:18070912]
[PUBMED:11058585]
[PUBMED:12890755]
[PUBMED:9184223]
[PUBMED:12058076]
[PUBMED:12226752]
[PUBMED:19435801]
[PUBMED:10212207]
[PUBMED:10521463]
[PUBMED:16159962]
[PUBMED:7579684]
[PUBMED:18362184]
[PUBMED:7997267]
[PUBMED:8816475]
[PUBMED:11279163]
[PUBMED:7537852]
[PUBMED:11418135]
[PUBMED:12167697]
[PUBMED:12615911]
[PUBMED:12876277]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
Vascular smooth muscle contraction
[NCBI:96530]
[KEGG:hsa04270]
[PUBMED:16870827]
[PUBMED:10911373]
[PUBMED:11679404]
[PUBMED:16339747]
[PUBMED:10221985]
[PUBMED:12689814]
[PUBMED:11165670]
[PUBMED:18552454]
[PUBMED:12060106]
[PUBMED:9458738]
[PUBMED:15725705]
[PUBMED:18040024]
[PUBMED:12693609]
[PUBMED:11773611]
[PUBMED:17158339]
[PUBMED:17458653]
[PUBMED:15026027]
[PUBMED:19120701]
[PUBMED:15269340]
[PUBMED:18703404]
[PUBMED:11709400]
[PUBMED:17200683]
p75 NTR receptor-mediated signalling
[NCBI:1269445]
[REACTOME:R-HSA-193704]
[PUBMED:16699811]
[PUBMED:16939974]
[PUBMED:12671646]