full name
synaptotagmin 1

synonyms
P65, SVP65, SYT, SYT1, ENSG00000067715

HGNC
HGNC:11509

Entrez Gene
Gene:6857

ENSEMBL
ENSG00000067715

location
chr: 12
start: 79257773
stop: 79845788
strand: +

OMIM
OMIM:185605: SYT1
OMIM:618218: Baker-Gordon syndrome

transcripts
NM_001135805.1
NM_005639.2
NM_001135806.1

pathways
Acetylcholine Neurotransmitter Release Cycle [NCBI:1268773] [REACTOME:R-HSA-264642] [PUBMED:18029057]
Cargo recognition for clathrin-mediated endocytosis [NCBI:1427859] [REACTOME:R-HSA-8856825] [PUBMED:24186068] [PUBMED:12952941] [PUBMED:19696796] [PUBMED:14985334] [PUBMED:20448150] [PUBMED:20485680] [PUBMED:16382132] [PUBMED:23482940] [PUBMED:16870701]
Clathrin-mediated endocytosis [NCBI:1427858] [REACTOME:R-HSA-8856828] [PUBMED:16516836] [PUBMED:15339664] [PUBMED:19754444] [PUBMED:8552632] [PUBMED:21779028] [PUBMED:12353027] [PUBMED:23891661] [PUBMED:21613550] [PUBMED:20059951] [PUBMED:21447041] [PUBMED:17620409] [PUBMED:16903783] [PUBMED:21445324] [PUBMED:19696798] [PUBMED:26246598] [PUBMED:25085911] [PUBMED:24186068] [PUBMED:26829388] [PUBMED:27092250] [PUBMED:24581490] [PUBMED:26042225] [PUBMED:23823722] [PUBMED:24789820] [PUBMED:9736607] [PUBMED:23637288] [PUBMED:22233676] [PUBMED:19458185] [PUBMED:26403691] [PUBMED:19296720] [PUBMED:15703209] [PUBMED:20428113] [PUBMED:8953040] [PUBMED:1177317] [PUBMED:9092476] [PUBMED:26872272] [PUBMED:19092055]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Dopamine Neurotransmitter Release Cycle [NCBI:1268772] [REACTOME:R-HSA-212676] [PUBMED:16613554]
Effects of Botulinum toxin [NCBI:138028] [Pathway Interaction Database:botulinumtoxinpathway] [PUBMED:10582602] [PUBMED:8175689] [PUBMED:9783260] [PUBMED:8051110] [PUBMED:9886085] [PUBMED:7737992] [PUBMED:12089155] [PUBMED:8223654] [PUBMED:16052212] [PUBMED:15218059] [PUBMED:8505288] [PUBMED:15489225] [PUBMED:15935055] [PUBMED:14504267] [PUBMED:8103915] [PUBMED:7527117] [PUBMED:15123599] [PUBMED:9712688] [PUBMED:9252191]
GABA synthesis, release, reuptake and degradation [NCBI:1268774] [REACTOME:R-HSA-888590] [PUBMED:19428801] [PUBMED:16787421]
Glutamate Neurotransmitter Release Cycle [NCBI:1268771] [REACTOME:R-HSA-210500] [PUBMED:8825650] [PUBMED:11001057] [PUBMED:16990140] [PUBMED:10440375] [PUBMED:16704978] [PUBMED:17478680] [PUBMED:9701566]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Interactions of neurexins and neuroligins at synapses [NCBI:1427850] [REACTOME:R-HSA-6794361] [PUBMED:22424845] [PUBMED:23559421] [PUBMED:21155806] [PUBMED:17299456] [PUBMED:17275284]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotoxicity of clostridium toxins [NCBI:1269145] [REACTOME:R-HSA-168799] [PUBMED:6763707] [PUBMED:15217342] [PUBMED:8542759] [PUBMED:24106296] [PUBMED:14744243] [PUBMED:20233039] [PUBMED:12417130] [PUBMED:13678859]
Neurotransmitter Release Cycle [NCBI:1268768] [REACTOME:R-HSA-112310] [PUBMED:15217342] [PUBMED:16819626] [PUBMED:17880890] [PUBMED:16865347]
Norepinephrine Neurotransmitter Release Cycle [NCBI:1268769] [REACTOME:R-HSA-181430] [PUBMED:17891149] [PUBMED:17478680] [PUBMED:12519779]
Protein-protein interactions at synapses [NCBI:1427849] [REACTOME:R-HSA-6794362] [PUBMED:18923512] [PUBMED:16337696] [PUBMED:17299456]
Serotonin Neurotransmitter Release Cycle [NCBI:1268770] [REACTOME:R-HSA-181429]
Synaptic vesicle cycle [NCBI:373900] [KEGG:hsa04721] [PUBMED:20634814] [PUBMED:17767192] [PUBMED:12094216] [PUBMED:16990140] [PUBMED:18726177] [PUBMED:18275379] [PUBMED:12827282] [PUBMED:12154365] [PUBMED:10212473] [PUBMED:15217342] [PUBMED:7791897] [PUBMED:12563290]
Toxicity of botulinum toxin type B (BoNT/B) [NCBI:1269147] [REACTOME:R-HSA-5250958] [PUBMED:14504267] [PUBMED:20233039] [PUBMED:15217342] [PUBMED:24165130] [PUBMED:7803399] [PUBMED:8542759] [PUBMED:23239348] [PUBMED:1331807] [PUBMED:15514477]
Toxicity of botulinum toxin type G (BoNT/G) [NCBI:1269153] [REACTOME:R-HSA-5250989] [PUBMED:20233039] [PUBMED:23647335] [PUBMED:22454523] [PUBMED:8542759] [PUBMED:7910017] [PUBMED:8051110]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]
Uptake and actions of bacterial toxins [NCBI:1269144] [REACTOME:R-HSA-5339562] [PUBMED:20358680]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]