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Genes
SYT1
Gene - SYT1
full name
synaptotagmin 1
synonyms
P65, SVP65, SYT, SYT1, ENSG00000067715
HGNC
HGNC:11509
Entrez Gene
Gene:6857
ENSEMBL
ENSG00000067715
location
chr: 12
start: 79257773
stop: 79845788
strand: +
OMIM
OMIM:185605
: SYT1
OMIM:618218
: Baker-Gordon syndrome
transcripts
NM_001135805.1
NM_005639.2
NM_001135806.1
pathways
Acetylcholine Neurotransmitter Release Cycle
[NCBI:1268773]
[REACTOME:R-HSA-264642]
[PUBMED:18029057]
Cargo recognition for clathrin-mediated endocytosis
[NCBI:1427859]
[REACTOME:R-HSA-8856825]
[PUBMED:24186068]
[PUBMED:12952941]
[PUBMED:19696796]
[PUBMED:14985334]
[PUBMED:20448150]
[PUBMED:20485680]
[PUBMED:16382132]
[PUBMED:23482940]
[PUBMED:16870701]
Clathrin-mediated endocytosis
[NCBI:1427858]
[REACTOME:R-HSA-8856828]
[PUBMED:16516836]
[PUBMED:15339664]
[PUBMED:19754444]
[PUBMED:8552632]
[PUBMED:21779028]
[PUBMED:12353027]
[PUBMED:23891661]
[PUBMED:21613550]
[PUBMED:20059951]
[PUBMED:21447041]
[PUBMED:17620409]
[PUBMED:16903783]
[PUBMED:21445324]
[PUBMED:19696798]
[PUBMED:26246598]
[PUBMED:25085911]
[PUBMED:24186068]
[PUBMED:26829388]
[PUBMED:27092250]
[PUBMED:24581490]
[PUBMED:26042225]
[PUBMED:23823722]
[PUBMED:24789820]
[PUBMED:9736607]
[PUBMED:23637288]
[PUBMED:22233676]
[PUBMED:19458185]
[PUBMED:26403691]
[PUBMED:19296720]
[PUBMED:15703209]
[PUBMED:20428113]
[PUBMED:8953040]
[PUBMED:1177317]
[PUBMED:9092476]
[PUBMED:26872272]
[PUBMED:19092055]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Dopamine Neurotransmitter Release Cycle
[NCBI:1268772]
[REACTOME:R-HSA-212676]
[PUBMED:16613554]
Effects of Botulinum toxin
[NCBI:138028]
[Pathway Interaction Database:botulinumtoxinpathway]
[PUBMED:10582602]
[PUBMED:8175689]
[PUBMED:9783260]
[PUBMED:8051110]
[PUBMED:9886085]
[PUBMED:7737992]
[PUBMED:12089155]
[PUBMED:8223654]
[PUBMED:16052212]
[PUBMED:15218059]
[PUBMED:8505288]
[PUBMED:15489225]
[PUBMED:15935055]
[PUBMED:14504267]
[PUBMED:8103915]
[PUBMED:7527117]
[PUBMED:15123599]
[PUBMED:9712688]
[PUBMED:9252191]
GABA synthesis, release, reuptake and degradation
[NCBI:1268774]
[REACTOME:R-HSA-888590]
[PUBMED:19428801]
[PUBMED:16787421]
Glutamate Neurotransmitter Release Cycle
[NCBI:1268771]
[REACTOME:R-HSA-210500]
[PUBMED:8825650]
[PUBMED:11001057]
[PUBMED:16990140]
[PUBMED:10440375]
[PUBMED:16704978]
[PUBMED:17478680]
[PUBMED:9701566]
Infectious disease
[NCBI:1269056]
[REACTOME:R-HSA-5663205]
Interactions of neurexins and neuroligins at synapses
[NCBI:1427850]
[REACTOME:R-HSA-6794361]
[PUBMED:22424845]
[PUBMED:23559421]
[PUBMED:21155806]
[PUBMED:17299456]
[PUBMED:17275284]
Membrane Trafficking
[NCBI:1269877]
[REACTOME:R-HSA-199991]
[PUBMED:11031247]
Neuronal System
[NCBI:1268763]
[REACTOME:R-HSA-112316]
Neurotoxicity of clostridium toxins
[NCBI:1269145]
[REACTOME:R-HSA-168799]
[PUBMED:6763707]
[PUBMED:15217342]
[PUBMED:8542759]
[PUBMED:24106296]
[PUBMED:14744243]
[PUBMED:20233039]
[PUBMED:12417130]
[PUBMED:13678859]
Neurotransmitter Release Cycle
[NCBI:1268768]
[REACTOME:R-HSA-112310]
[PUBMED:15217342]
[PUBMED:16819626]
[PUBMED:17880890]
[PUBMED:16865347]
Norepinephrine Neurotransmitter Release Cycle
[NCBI:1268769]
[REACTOME:R-HSA-181430]
[PUBMED:17891149]
[PUBMED:17478680]
[PUBMED:12519779]
Protein-protein interactions at synapses
[NCBI:1427849]
[REACTOME:R-HSA-6794362]
[PUBMED:18923512]
[PUBMED:16337696]
[PUBMED:17299456]
Serotonin Neurotransmitter Release Cycle
[NCBI:1268770]
[REACTOME:R-HSA-181429]
Synaptic vesicle cycle
[NCBI:373900]
[KEGG:hsa04721]
[PUBMED:20634814]
[PUBMED:17767192]
[PUBMED:12094216]
[PUBMED:16990140]
[PUBMED:18726177]
[PUBMED:18275379]
[PUBMED:12827282]
[PUBMED:12154365]
[PUBMED:10212473]
[PUBMED:15217342]
[PUBMED:7791897]
[PUBMED:12563290]
Toxicity of botulinum toxin type B (BoNT/B)
[NCBI:1269147]
[REACTOME:R-HSA-5250958]
[PUBMED:14504267]
[PUBMED:20233039]
[PUBMED:15217342]
[PUBMED:24165130]
[PUBMED:7803399]
[PUBMED:8542759]
[PUBMED:23239348]
[PUBMED:1331807]
[PUBMED:15514477]
Toxicity of botulinum toxin type G (BoNT/G)
[NCBI:1269153]
[REACTOME:R-HSA-5250989]
[PUBMED:20233039]
[PUBMED:23647335]
[PUBMED:22454523]
[PUBMED:8542759]
[PUBMED:7910017]
[PUBMED:8051110]
Transmission across Chemical Synapses
[NCBI:1268766]
[REACTOME:R-HSA-112315]
Uptake and actions of bacterial toxins
[NCBI:1269144]
[REACTOME:R-HSA-5339562]
[PUBMED:20358680]
Vesicle-mediated transport
[NCBI:1269876]
[REACTOME:R-HSA-5653656]