full name
ATPase plasma membrane Ca2+ transporting 1

synonyms
PMCA1, PMCA1kb, ATP2B1, ENSG00000070961

HGNC
HGNC:814

Entrez Gene
Gene:490

ENSEMBL
ENSG00000070961

location
chr: 12
start: 89981826
stop: 90103130
strand: -

transcripts
NM_001682.2
NM_001001323.1

pathways
Adrenergic signaling in cardiomyocytes [NCBI:908257] [KEGG:hsa04261] [PUBMED:15232578] [PUBMED:20923637] [PUBMED:10571541] [PUBMED:11604549] [PUBMED:17988210] [PUBMED:11805843] [PUBMED:15142747] [PUBMED:21212391] [PUBMED:20658186] [PUBMED:16765984] [PUBMED:19874988] [PUBMED:19883653] [PUBMED:15979723] [PUBMED:18407781] [PUBMED:22022314] [PUBMED:12439640] [PUBMED:17826821] [PUBMED:15765137]
C-MYB transcription factor network [NCBI:138073] [Pathway Interaction Database:cmyb_pathway] [PUBMED:17152050] [PUBMED:1944282] [PUBMED:7964503] [PUBMED:8598284] [PUBMED:15608679] [PUBMED:10619021] [PUBMED:2233716] [PUBMED:9244354] [PUBMED:8654374] [PUBMED:10590070] [PUBMED:17587615] [PUBMED:12424255] [PUBMED:1679531] [PUBMED:17077080] [PUBMED:8946914] [PUBMED:16055116] [PUBMED:11259163] [PUBMED:9659917] [PUBMED:9135152] [PUBMED:7721782] [PUBMED:11290610] [PUBMED:12244173] [PUBMED:11792321] [PUBMED:17242210] [PUBMED:10722757] [PUBMED:8264615] [PUBMED:15687240] [PUBMED:14761981] [PUBMED:10542314] [PUBMED:12673198] [PUBMED:11779867] [PUBMED:8756344] [PUBMED:11427482] [PUBMED:9809063] [PUBMED:10523863] [PUBMED:11094072] [PUBMED:15356292] [PUBMED:11781241] [PUBMED:15778089] [PUBMED:9096387] [PUBMED:17931383] [PUBMED:14576818] [PUBMED:11259170] [PUBMED:8491193] [PUBMED:11581319] [PUBMED:10644988] [PUBMED:7565722] [PUBMED:9490676] [PUBMED:9244356] [PUBMED:17641686] [PUBMED:16407849] [PUBMED:1594249] [PUBMED:17822556] [PUBMED:15867358] [PUBMED:17959653] [PUBMED:7509358] [PUBMED:11287612] [PUBMED:15082531] [PUBMED:10766162] [PUBMED:8756629] [PUBMED:11115410] [PUBMED:7684005] [PUBMED:9566892]
Calcium signaling pathway [NCBI:83050] [KEGG:hsa04020] [PUBMED:11080247] [PUBMED:14572802] [PUBMED:11413485] [PUBMED:22129055] [PUBMED:10508738] [PUBMED:15000521] [PUBMED:9235901] [PUBMED:7861177] [PUBMED:9149541] [PUBMED:14517314] [PUBMED:15111104] [PUBMED:11698232] [PUBMED:10331643] [PUBMED:12838335] [PUBMED:8125957] [PUBMED:19172794] [PUBMED:10997573] [PUBMED:21338471] [PUBMED:11299192] [PUBMED:22002090] [PUBMED:12972622]
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:19808464] [PUBMED:26140724] [PUBMED:21357845]
Endocrine and other factor-regulated calcium reabsorption [NCBI:213307] [KEGG:hsa04961] [PUBMED:15747113] [PUBMED:20969972] [PUBMED:15618484] [PUBMED:18989697] [PUBMED:19423690] [PUBMED:18293139] [PUBMED:18596722] [PUBMED:16518325] [PUBMED:17006539] [PUBMED:12684797] [PUBMED:17233615] [PUBMED:16044309]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Ion channel transport [NCBI:1269950] [REACTOME:R-HSA-983712] [PUBMED:15071553]
Ion homeostasis [NCBI:1339121] [REACTOME:R-HSA-5578775] [PUBMED:26140724] [PUBMED:17017901]
Ion transport by P-type ATPases [NCBI:1269951] [REACTOME:R-HSA-936837] [PUBMED:15071553]
Mineral absorption [NCBI:212237] [KEGG:hsa04978] [PUBMED:20120011] [PUBMED:12520535] [PUBMED:15618484] [PUBMED:17194590] [PUBMED:21054167] [PUBMED:19448074] [PUBMED:18779302] [PUBMED:18598134] [PUBMED:18277073] [PUBMED:18301276] [PUBMED:19400752] [PUBMED:16431934] [PUBMED:19729436] [PUBMED:18636652] [PUBMED:17943492] [PUBMED:16565477] [PUBMED:18779306]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Pancreatic secretion [NCBI:169306] [KEGG:hsa04972] [PUBMED:16888148] [PUBMED:9548666] [PUBMED:20224219] [PUBMED:19088252] [PUBMED:15709963] [PUBMED:10078532] [PUBMED:15689674] [PUBMED:10835353] [PUBMED:14660554] [PUBMED:20625287] [PUBMED:16930743] [PUBMED:14637169] [PUBMED:16891880] [PUBMED:18626068] [PUBMED:11087843] [PUBMED:17850212] [PUBMED:17205399]
Platelet calcium homeostasis [NCBI:1269345] [REACTOME:R-HSA-418360] [PUBMED:18308196] [PUBMED:19422456]
Platelet homeostasis [NCBI:1269341] [REACTOME:R-HSA-418346] [PUBMED:10798271]
Reduction of cytosolic Ca++ levels [NCBI:1269347] [REACTOME:R-HSA-418359] [PUBMED:18308196]
Salivary secretion [NCBI:153376] [KEGG:hsa04970] [PUBMED:8105741] [PUBMED:10682899] [PUBMED:10928320] [PUBMED:15709965] [PUBMED:17347411] [PUBMED:9720759] [PUBMED:16712780] [PUBMED:16799262] [PUBMED:17157080] [PUBMED:18626068] [PUBMED:15153696] [PUBMED:11936453] [PUBMED:20224180]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
cAMP signaling pathway [NCBI:1017634] [KEGG:hsa04024] [PUBMED:10880354] [PUBMED:9204709] [PUBMED:21693691] [PUBMED:24062645] [PUBMED:24450633] [PUBMED:21346730] [PUBMED:24613710] [PUBMED:21744067] [PUBMED:22082266] [PUBMED:16460276] [PUBMED:18176800] [PUBMED:14715909] [PUBMED:7688165] [PUBMED:24281338] [PUBMED:11117527] [PUBMED:16765984] [PUBMED:18323530] [PUBMED:18064650] [PUBMED:21852968] [PUBMED:11493633] [PUBMED:21212391] [PUBMED:15142747] [PUBMED:17077866] [PUBMED:19460777] [PUBMED:19874988] [PUBMED:16571352] [PUBMED:22022314]
cGMP-PKG signaling pathway [NCBI:983748] [KEGG:hsa04022] [PUBMED:18006449] [PUBMED:9003029] [PUBMED:18040025] [PUBMED:19306895] [PUBMED:21666108] [PUBMED:12524221] [PUBMED:16460276] [PUBMED:20716671] [PUBMED:22785374] [PUBMED:11522789] [PUBMED:16439998] [PUBMED:16371594] [PUBMED:20388537] [PUBMED:18757523] [PUBMED:16815627] [PUBMED:23212367] [PUBMED:21685243] [PUBMED:20024580] [PUBMED:15894227] [PUBMED:22965426] [PUBMED:17643091] [PUBMED:19176601] [PUBMED:19961855]