full name
lumican

synonyms
LDC, SLRR2D, LUM, ENSG00000139329

HGNC
HGNC:6724

Entrez Gene
Gene:4060

ENSEMBL
ENSG00000139329

location
chr: 12
start: 91497232
stop: 91505542
strand: -

transcripts
NM_002345.3

pathways
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) [NCBI:1269019] [REACTOME:R-HSA-3656244] [NCBI:1269037] [REACTOME:R-HSA-4793953] [PUBMED:11901181] [PUBMED:23622397]
Defective CHST6 causes MCDC1 [NCBI:1269020] [REACTOME:R-HSA-3656225] [PUBMED:3293458] [PUBMED:6238957] [PUBMED:13790593]
Defective ST3GAL3 causes MCT12 and EIEE15 [NCBI:1309216] [REACTOME:R-HSA-3656243] [PUBMED:23252400] [PUBMED:17120046] [PUBMED:21907012]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases associated with glycosaminoglycan metabolism [NCBI:1269011] [REACTOME:R-HSA-3560782] [PUBMED:23457301]
Diseases of glycosylation [NCBI:1269010] [REACTOME:R-HSA-3781865] [PUBMED:22983739] [PUBMED:12756558] [PUBMED:22343051] [PUBMED:6543331] [PUBMED:16755287] [PUBMED:19765534] [PUBMED:12409504] [PUBMED:22838182] [PUBMED:2301971] [PUBMED:21384229]
ECM proteoglycans [NCBI:1270256] [REACTOME:R-HSA-3000178] [PUBMED:20301236] [PUBMED:21307119]
Extracellular matrix organization [NCBI:1270244] [REACTOME:R-HSA-1474244] [PUBMED:21123617] [PUBMED:21917992] [PUBMED:12845610]
Glycosaminoglycan metabolism [NCBI:1269972] [REACTOME:R-HSA-1630316] [PUBMED:18201392] [PUBMED:20301236] [PUBMED:820626]
Integrin cell surface interactions [NCBI:1270260] [REACTOME:R-HSA-216083] [PUBMED:10215583] [PUBMED:15147720] [PUBMED:12231361] [PUBMED:8866399] [PUBMED:19273203]
Keratan sulfate biosynthesis [NCBI:1269978] [REACTOME:R-HSA-2022854] [PUBMED:12512857] [PUBMED:20213925] [PUBMED:11030741]
Keratan sulfate degradation [NCBI:413378] [KEGG:hsa_M00079] [NCBI:1269979] [REACTOME:R-HSA-2022857] [PUBMED:2531691] [PUBMED:15647514]
Keratan sulfate/keratin metabolism [NCBI:1269977] [REACTOME:R-HSA-1638074] [PUBMED:11030741] [PUBMED:16287098] [PUBMED:12512857]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Proteoglycans in cancer [NCBI:782000] [KEGG:hsa05205] [PUBMED:19433454] [PUBMED:20655987] [PUBMED:18798267] [PUBMED:10633082] [PUBMED:10687947] [PUBMED:22735579] [PUBMED:24412155] [PUBMED:9346940] [PUBMED:22087031] [PUBMED:22194599] [PUBMED:14711376] [PUBMED:19255147] [PUBMED:15655247] [PUBMED:11717317] [PUBMED:17971838] [PUBMED:18413366] [PUBMED:20974860] [PUBMED:11830493] [PUBMED:23058688] [PUBMED:18450475] [PUBMED:12748184] [PUBMED:19733083] [PUBMED:18812315] [PUBMED:12509413] [PUBMED:21155971] [PUBMED:11931647] [PUBMED:18949819] [PUBMED:12729888] [PUBMED:15994311] [PUBMED:23305321] [PUBMED:18505598] [PUBMED:22563565] [PUBMED:22033227]