full name
CASP2 and RIPK1 domain containing adaptor with death domain

synonyms
MRT34, RAIDD, CRADD, ENSG00000169372

HGNC
HGNC:2340

Entrez Gene
Gene:8738

ENSEMBL
ENSG00000169372

location
chr: 12
start: 94071121
stop: 94289530
strand: +

OMIM
OMIM:603454: CRADD (Autosomal recessive inheritance)
OMIM:614499: Mental retardation, autosomal recessive 34, with variant lissencephaly

transcripts
NM_003805.3

pathways
Caspase cascade in apoptosis [NCBI:137974] [Pathway Interaction Database:caspase_pathway] [PUBMED:7774019] [PUBMED:8626669] [PUBMED:9850096] [PUBMED:11803376] [PUBMED:15189451] [PUBMED:10564664] [PUBMED:9642276] [PUBMED:10567584] [PUBMED:12419244] [PUBMED:11423904] [PUBMED:9422506] [PUBMED:11438643] [PUBMED:9070648] [PUBMED:9588194] [PUBMED:11085743] [PUBMED:9298992] [PUBMED:9933635] [PUBMED:9528810] [PUBMED:9323209] [PUBMED:10809769] [PUBMED:8700869] [PUBMED:9463409] [PUBMED:10497198] [PUBMED:11953316] [PUBMED:9422513] [PUBMED:10409650] [PUBMED:11463840] [PUBMED:10611247] [PUBMED:8605870]
Ceramide signaling pathway [NCBI:138023] [Pathway Interaction Database:ceramide_pathway] [PUBMED:11350735] [PUBMED:10400650] [PUBMED:9287216] [PUBMED:9488730] [PUBMED:8702918] [PUBMED:10969079] [PUBMED:10433354] [PUBMED:14739942] [PUBMED:9446561] [PUBMED:8808629] [PUBMED:8681376] [PUBMED:7477354] [PUBMED:14689449] [PUBMED:12866359] [PUBMED:9873064] [PUBMED:8933152] [PUBMED:10438487] [PUBMED:15881228] [PUBMED:10508159] [PUBMED:7519779] [PUBMED:8387486] [PUBMED:12154098] [PUBMED:7559390] [PUBMED:12486111] [PUBMED:14670935] [PUBMED:15901738] [PUBMED:15051724] [PUBMED:8393446] [PUBMED:9094715] [PUBMED:11723139] [PUBMED:10395296] [PUBMED:8681377] [PUBMED:11148216] [PUBMED:12566438] [PUBMED:15164763] [PUBMED:10026132] [PUBMED:10962008]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
HIV-1 Nef: Negative effector of Fas and TNF-alpha [NCBI:137995] [Pathway Interaction Database:hivnefpathway] [PUBMED:9740801] [PUBMED:10224289] [PUBMED:10940292] [PUBMED:9915703] [PUBMED:9564042] [PUBMED:9743501] [PUBMED:9873064] [PUBMED:12748303] [PUBMED:9867840] [PUBMED:11298454] [PUBMED:9184224] [PUBMED:9294162] [PUBMED:9727492] [PUBMED:9244310] [PUBMED:10318789] [PUBMED:12887920] [PUBMED:9230442] [PUBMED:9020361] [PUBMED:9108473] [PUBMED:9215629] [PUBMED:9384571]
TP53 Regulates Transcription of Caspase Activators and Caspases [NCBI:1383069] [REACTOME:R-HSA-6803207] [PUBMED:15580302] [PUBMED:14688482] [PUBMED:10973264] [PUBMED:11278253] [PUBMED:12089322] [PUBMED:11559530] [PUBMED:17284521]
TP53 Regulates Transcription of Cell Death Genes [NCBI:1383066] [REACTOME:R-HSA-5633008] [PUBMED:20353938] [PUBMED:18676979] [PUBMED:11511362] [PUBMED:11919562] [PUBMED:10973264] [PUBMED:15797384] [PUBMED:17442733] [PUBMED:15607964] [PUBMED:11278253] [PUBMED:23059823] [PUBMED:19549844] [PUBMED:11684014] [PUBMED:7566179] [PUBMED:17349958] [PUBMED:24739573] [PUBMED:18719709] [PUBMED:17284521] [PUBMED:23703390] [PUBMED:10807576] [PUBMED:10733530] [PUBMED:12402042] [PUBMED:12851404] [PUBMED:14729977] [PUBMED:18431400] [PUBMED:15377670] [PUBMED:12089322] [PUBMED:15273740] [PUBMED:11382926] [PUBMED:12606722] [PUBMED:14623878] [PUBMED:15577913] [PUBMED:16230375] [PUBMED:26122615] [PUBMED:11559530] [PUBMED:11054413] [PUBMED:22766503] [PUBMED:11463392] [PUBMED:16249378] [PUBMED:9326928] [PUBMED:14614825] [PUBMED:19615968] [PUBMED:16140933] [PUBMED:7834749] [PUBMED:16135520] [PUBMED:15126337] [PUBMED:15580302] [PUBMED:15289308] [PUBMED:10777207] [PUBMED:23365256] [PUBMED:19040420] [PUBMED:15735003] [PUBMED:14688482]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]