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Genes
MYL2
Gene - MYL2
full name
myosin light chain 2
synonyms
CMH10, MLC2, MYL2, ENSG00000111245
HGNC
HGNC:7583
Entrez Gene
Gene:4633
ENSEMBL
ENSG00000111245
location
chr: 12
start: 111348623
stop: 111358404
strand: -
OMIM
OMIM:160781
: MYL2
(Autosomal dominant inheritance)
OMIM:608758
: Cardiomyopathy, hypertrophic, 10
transcripts
NM_000432.3
pathways
Adrenergic signaling in cardiomyocytes
[NCBI:908257]
[KEGG:hsa04261]
[PUBMED:15232578]
[PUBMED:20923637]
[PUBMED:10571541]
[PUBMED:11604549]
[PUBMED:17988210]
[PUBMED:11805843]
[PUBMED:15142747]
[PUBMED:21212391]
[PUBMED:20658186]
[PUBMED:16765984]
[PUBMED:19874988]
[PUBMED:19883653]
[PUBMED:15979723]
[PUBMED:18407781]
[PUBMED:22022314]
[PUBMED:12439640]
[PUBMED:17826821]
[PUBMED:15765137]
Apelin signaling pathway
[NCBI:1492886]
[KEGG:hsa04371]
[PUBMED:23973488]
[PUBMED:16182514]
[PUBMED:21725702]
[PUBMED:22842084]
[PUBMED:27825851]
[PUBMED:27650065]
[PUBMED:22140623]
[PUBMED:23943882]
[PUBMED:26944568]
[PUBMED:24055369]
[PUBMED:26385179]
[PUBMED:26143239]
[PUBMED:22028387]
[PUBMED:26254105]
[PUBMED:26756969]
[PUBMED:22995518]
[PUBMED:27979574]
[PUBMED:23924696]
[PUBMED:21464822]
[PUBMED:25914650]
[PUBMED:24990699]
[PUBMED:26607438]
[PUBMED:25164121]
[PUBMED:25275559]
[PUBMED:25139773]
[PUBMED:25931124]
[PUBMED:19093215]
[PUBMED:20539939]
[PUBMED:25652330]
[PUBMED:18272138]
[PUBMED:23603510]
CDC42 signaling events
[NCBI:137994]
[Pathway Interaction Database:cdc42_pathway]
[PUBMED:7629060]
[PUBMED:7652575]
[PUBMED:8653792]
[PUBMED:18448434]
[PUBMED:19822663]
[PUBMED:19454477]
[PUBMED:18662680]
[PUBMED:15882626]
[PUBMED:11948177]
[PUBMED:9860974]
[PUBMED:15225553]
[PUBMED:8643625]
[PUBMED:8107774]
[PUBMED:8670801]
[PUBMED:8034624]
[PUBMED:10934474]
[PUBMED:10734320]
[PUBMED:17522712]
[PUBMED:11525734]
[PUBMED:15649357]
[PUBMED:10473551]
[PUBMED:16157700]
[PUBMED:9822598]
[PUBMED:15723051]
[PUBMED:7600582]
[PUBMED:18319301]
[PUBMED:9042860]
[PUBMED:10613909]
[PUBMED:17580073]
[PUBMED:12745076]
[PUBMED:16253996]
[PUBMED:10840034]
[PUBMED:10360579]
[PUBMED:11907268]
[PUBMED:10934475]
[PUBMED:10219243]
[PUBMED:17038317]
[PUBMED:8910292]
[PUBMED:9403696]
[PUBMED:11285260]
[PUBMED:10995437]
[PUBMED:9368021]
[PUBMED:14970210]
[PUBMED:9694656]
[PUBMED:14505571]
[PUBMED:17115031]
[PUBMED:9317150]
[PUBMED:14653992]
[PUBMED:17081755]
[PUBMED:12676083]
[PUBMED:18216334]
[PUBMED:19826000]
[PUBMED:8702968]
[PUBMED:11304531]
[PUBMED:10973943]
[PUBMED:11309380]
[PUBMED:18586681]
[PUBMED:15479449]
[PUBMED:19097998]
[PUBMED:16892055]
[PUBMED:17244649]
[PUBMED:8625410]
[PUBMED:8497321]
[PUBMED:15485841]
[PUBMED:16407834]
[PUBMED:11804587]
[PUBMED:9867866]
[PUBMED:10747870]
[PUBMED:7600581]
[PUBMED:12610628]
[PUBMED:19435802]
[PUBMED:15572110]
[PUBMED:7592586]
[PUBMED:11696321]
[PUBMED:10559936]
Cardiac muscle contraction
[NCBI:93344]
[KEGG:hsa04260]
[PUBMED:16799263]
[PUBMED:18981594]
[PUBMED:12763850]
[PUBMED:16096350]
[PUBMED:16552170]
[PUBMED:15736582]
[PUBMED:14659803]
[PUBMED:17988210]
[PUBMED:11805843]
[PUBMED:10747208]
[PUBMED:16701909]
[PUBMED:11294886]
Dilated cardiomyopathy
[NCBI:121494]
[KEGG:hsa05414]
[PUBMED:11524405]
[PUBMED:11805847]
[PUBMED:12270949]
[PUBMED:14522402]
[PUBMED:19017683]
[PUBMED:15146239]
[PUBMED:18672201]
[PUBMED:19273156]
[PUBMED:19246813]
[PUBMED:11716909]
[PUBMED:16817756]
Focal adhesion
[NCBI:83067]
[KEGG:hsa04510]
[PUBMED:10698680]
[PUBMED:15459662]
[PUBMED:14756624]
[PUBMED:11573199]
[PUBMED:12640026]
[PUBMED:15179030]
[PUBMED:15108811]
[PUBMED:15053919]
[PUBMED:11082269]
[PUBMED:15034601]
[PUBMED:12235283]
[PUBMED:14519391]
[PUBMED:11146675]
[PUBMED:11229600]
[PUBMED:15688067]
[PUBMED:14744429]
[PUBMED:11882383]
Hypertrophic cardiomyopathy (HCM)
[NCBI:114229]
[KEGG:hsa05410]
[PUBMED:11805847]
[PUBMED:18572189]
[PUBMED:14711353]
[PUBMED:19136482]
[PUBMED:18056765]
[PUBMED:11225594]
[PUBMED:12844200]
[PUBMED:10615904]
[PUBMED:11716909]
[PUBMED:11371514]
[PUBMED:12270949]
Leukocyte transendothelial migration
[NCBI:83083]
[KEGG:hsa04670]
[PUBMED:15629883]
[PUBMED:10975856]
[PUBMED:14976004]
[PUBMED:15265790]
[PUBMED:15173832]
[PUBMED:12540948]
[PUBMED:15771581]
[PUBMED:15604886]
[PUBMED:14977592]
Muscle contraction
[NCBI:1269868]
[REACTOME:R-HSA-397014]
N-cadherin signaling events
[NCBI:137919]
[Pathway Interaction Database:ncadherinpathway]
[PUBMED:16319177]
[PUBMED:19075000]
[PUBMED:15121175]
[PUBMED:15226396]
[PUBMED:17765222]
[PUBMED:7885471]
[PUBMED:11086998]
[PUBMED:2318342]
[PUBMED:8050374]
[PUBMED:9655503]
[PUBMED:7962102]
[PUBMED:7599959]
[PUBMED:17459003]
[PUBMED:9852580]
[PUBMED:9052794]
[PUBMED:17005551]
[PUBMED:1837087]
[PUBMED:1639850]
[PUBMED:16176974]
[PUBMED:16807326]
[PUBMED:15716354]
[PUBMED:8707857]
[PUBMED:19162191]
[PUBMED:12099895]
[PUBMED:8113807]
[PUBMED:16228908]
[PUBMED:17538019]
[PUBMED:11056534]
[PUBMED:11809840]
[PUBMED:11571292]
[PUBMED:12377785]
[PUBMED:8909549]
[PUBMED:3780667]
[PUBMED:9655504]
[PUBMED:14610057]
[PUBMED:15569714]
[PUBMED:15662031]
[PUBMED:15809310]
[PUBMED:15247242]
[PUBMED:2762814]
[PUBMED:17289573]
[PUBMED:17921113]
[PUBMED:9712659]
[PUBMED:12578907]
[PUBMED:16515543]
[PUBMED:15034585]
[PUBMED:11106648]
[PUBMED:11228159]
[PUBMED:9786960]
[PUBMED:12604612]
[PUBMED:11466312]
[PUBMED:11238727]
[PUBMED:12640032]
[PUBMED:1487503]
[PUBMED:15383621]
[PUBMED:8816706]
[PUBMED:17481398]
[PUBMED:9545083]
[PUBMED:14657280]
[PUBMED:12213839]
[PUBMED:10930450]
Regulation of actin cytoskeleton
[NCBI:83089]
[KEGG:hsa04810]
[PUBMED:11152757]
[PUBMED:11082272]
[PUBMED:10574699]
[PUBMED:11082269]
[PUBMED:14657486]
[PUBMED:14744429]
[PUBMED:12700767]
RhoA signaling pathway
[NCBI:169356]
[Pathway Interaction Database:rhoa_pathway]
[PUBMED:8641286]
[PUBMED:16705166]
[PUBMED:9510209]
[PUBMED:18267089]
[PUBMED:15866170]
[PUBMED:18303050]
[PUBMED:17588931]
[PUBMED:18941185]
[PUBMED:16164598]
[PUBMED:11238375]
[PUBMED:18559669]
[PUBMED:18025109]
[PUBMED:16427251]
[PUBMED:11122380]
[PUBMED:8632828]
[PUBMED:15866889]
[PUBMED:9707430]
[PUBMED:9456324]
[PUBMED:8662509]
[PUBMED:12429848]
[PUBMED:9294169]
[PUBMED:9042860]
[PUBMED:9582304]
[PUBMED:15170389]
[PUBMED:10744700]
[PUBMED:10893221]
[PUBMED:14681219]
[PUBMED:9121475]
[PUBMED:8858161]
[PUBMED:18309323]
[PUBMED:9710582]
[PUBMED:9265657]
[PUBMED:19625450]
[PUBMED:15068801]
[PUBMED:11278519]
[PUBMED:12732141]
[PUBMED:9529607]
[PUBMED:12600823]
[PUBMED:9697773]
[PUBMED:10085083]
[PUBMED:12802051]
[PUBMED:11018042]
[PUBMED:7600583]
[PUBMED:9693382]
[PUBMED:12899698]
[PUBMED:8702756]
[PUBMED:10556088]
[PUBMED:10037681]
[PUBMED:1643657]
[PUBMED:12034774]
[PUBMED:9670022]
[PUBMED:12574166]
[PUBMED:12584113]
[PUBMED:11877391]
[PUBMED:9920882]
[PUBMED:8995216]
[PUBMED:7929302]
[PUBMED:10428028]
[PUBMED:15793569]
[PUBMED:14595335]
[PUBMED:10436006]
[PUBMED:9482732]
[PUBMED:11342553]
[PUBMED:9351440]
Stabilization and expansion of the E-cadherin adherens junction
[NCBI:137918]
[Pathway Interaction Database:ecadherin_stabilization_pathway]
[PUBMED:15057284]
[PUBMED:10769210]
[PUBMED:17261850]
[PUBMED:18413140]
[PUBMED:14704278]
[PUBMED:19041755]
[PUBMED:18690644]
[PUBMED:16030252]
[PUBMED:16537539]
[PUBMED:19193766]
[PUBMED:11381089]
[PUBMED:16613855]
[PUBMED:7962096]
[PUBMED:17940061]
[PUBMED:10511313]
[PUBMED:8660958]
[PUBMED:7790378]
[PUBMED:18093941]
[PUBMED:14709721]
[PUBMED:17761530]
[PUBMED:16371509]
[PUBMED:11024053]
[PUBMED:19158278]
[PUBMED:9182672]
[PUBMED:10085258]
[PUBMED:10660044]
[PUBMED:17646397]
[PUBMED:10980705]
[PUBMED:9566974]
[PUBMED:11056534]
[PUBMED:17664339]
[PUBMED:17635938]
Striated Muscle Contraction
[NCBI:1269869]
[REACTOME:R-HSA-390522]
[PUBMED:15173217]
[PUBMED:13165697]
[PUBMED:15173218]
[PUBMED:13175187]
Tight junction
[NCBI:83071]
[KEGG:hsa04530]
[PUBMED:25152334]
[PUBMED:16650994]
[PUBMED:22892070]
[PUBMED:18946474]
[PUBMED:12042308]
[PUBMED:23885123]
[PUBMED:16771626]
[PUBMED:17182900]
[PUBMED:21283798]
[PUBMED:25757376]
[PUBMED:22928510]
[PUBMED:22169974]
[PUBMED:25469537]
[PUBMED:24651541]
[PUBMED:15820555]
[PUBMED:17525755]
[PUBMED:27353478]
[PUBMED:17950242]
[PUBMED:18005931]
[PUBMED:24548561]
[PUBMED:21781017]
[PUBMED:20094051]
[PUBMED:20134025]
[PUBMED:22896795]
[PUBMED:18094055]
[PUBMED:25483301]