full name
aldehyde dehydrogenase 2 family (mitochondrial)

synonyms
ALDH-E2, ALDHI, ALDM, ALDH2, ENSG00000111275

HGNC
HGNC:404

Entrez Gene
Gene:217

ENSEMBL
ENSG00000111275

location
chr: 12
start: 112204691
stop: 112247789
strand: +

OMIM
OMIM:100650: ALDH2
OMIM:610251: Alcohol sensitivity, acute
OMIM:610251: {Hangover, susceptibility to}

transcripts
NM_000690.3
NM_001204889.1

pathways
Arginine and proline metabolism [NCBI:82957] [KEGG:hsa00330] [PUBMED:15590624] [PUBMED:5288244] [PUBMED:16499623]
Ascorbate and aldarate metabolism [NCBI:82932] [KEGG:hsa00053] [PUBMED:16595667] [PUBMED:12644495] [PUBMED:10517845] [PUBMED:17462988] [PUBMED:15564123] [PUBMED:17222174] [PUBMED:14996803]
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Ethanol oxidation [NCBI:1270206] [REACTOME:R-HSA-71384] [PUBMED:224930] [PUBMED:3893466] [PUBMED:18110463] [PUBMED:2729894] [PUBMED:17567461] [PUBMED:9982] [PUBMED:10441588]
Fatty acid degradation [NCBI:82935] [KEGG:hsa00071] [PUBMED:869535]
GABA biosynthesis, eukaryotes, putrescine => GABA [NCBI:413399] [KEGG:hsa_M00135]
Glycerolipid metabolism [NCBI:82986] [KEGG:hsa00561] [PUBMED:11294844] [PUBMED:8662716] [PUBMED:8995384]
Glycolysis / Gluconeogenesis [NCBI:82926] [KEGG:hsa00010]
Histidine metabolism [NCBI:82958] [KEGG:hsa00340]
Lysine degradation [NCBI:82956] [KEGG:hsa00310] [PUBMED:11802770] [PUBMED:1682209]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of serotonin [NCBI:1268783] [REACTOME:R-HSA-380612]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotransmitter Clearance In The Synaptic Cleft [NCBI:1268778] [REACTOME:R-HSA-112311]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]
Pyruvate metabolism [NCBI:82998] [KEGG:hsa00620] [NCBI:1270123] [REACTOME:R-HSA-70268] [PUBMED:2188967] [PUBMED:7273846]
Serotonin clearance from the synaptic cleft [NCBI:1268782] [REACTOME:R-HSA-380615]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]
Tryptophan metabolism [NCBI:82964] [KEGG:hsa00380] [PUBMED:15749753]
Valine, leucine and isoleucine degradation [NCBI:82952] [KEGG:hsa00280]
beta-Alanine metabolism [NCBI:82966] [KEGG:hsa00410]
ethanol degradation II [NCBI:142309] [BIOCYC:HUMAN_PWY66-21] [PUBMED:12065293] [PUBMED:11420176] [PUBMED:3519419] [PUBMED:12870777] [PUBMED:12456329] [PUBMED:12901271]
ethanol degradation IV [NCBI:142308] [BIOCYC:HUMAN_PWY66-162] [PUBMED:12870777] [PUBMED:12901271] [PUBMED:12456329] [PUBMED:3519419] [PUBMED:12065293] [PUBMED:11420176]
noradrenaline and adrenaline degradation [NCBI:545354] [BIOCYC:HUMAN_PWY-6342] [PUBMED:9360553] [PUBMED:12649306] [PUBMED:3466164] [PUBMED:3996536] [PUBMED:15317907]
oxidative ethanol degradation III [NCBI:142307] [BIOCYC:HUMAN_PWY66-161] [PUBMED:3519419] [PUBMED:12065293] [PUBMED:12901271] [PUBMED:12870777] [PUBMED:11420176] [PUBMED:12456329]
phenylethylamine degradation I [NCBI:547500] [BIOCYC:HUMAN_2PHENDEG-PWY]
putrescine degradation III [NCBI:545337] [BIOCYC:HUMAN_PWY-0] [PUBMED:2185470] [PUBMED:3157043] [PUBMED:4873311] [PUBMED:8223591] [PUBMED:4156831] [PUBMED:1409623]
serotonin degradation [NCBI:545353] [BIOCYC:HUMAN_PWY-6313] [PUBMED:14678785] [PUBMED:17908235] [PUBMED:12231396] [PUBMED:12899690] [PUBMED:19264685] [PUBMED:16537538] [PUBMED:3459671] [PUBMED:17877637] [PUBMED:7752817] [PUBMED:18651566] [PUBMED:15677341]
superpathway of tryptophan utilization [NCBI:835392] [BIOCYC:HUMAN_PWY66-401]