full name
protein tyrosine phosphatase, non-receptor type 11
synonyms
BPTP3, CFC, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2, PTPN11, ENSG00000179295
HGNC
HGNC:9644
Entrez Gene
Gene:5781
ENSEMBL
ENSG00000179295
location
chr: 12
start: 112856536
stop: 112947717
strand: +
OMIM
OMIM:176876:
PTPN11
(Autosomal dominant inheritance)
OMIM:151100:
LEOPARD syndrome 1
OMIM:607785:
Leukemia, juvenile myelomonocytic, somatic
OMIM:156250:
Metachondromatosis
OMIM:163950:
Noonan syndrome 1
transcripts
NM_002834.3
NM_080601.1
pathways
Activated TLR4 signalling
[NCBI:1269236]
[REACTOME:R-HSA-166054]
[PUBMED:15276183]
[PUBMED:15588429]
[PUBMED:15845500]
[PUBMED:15596121]
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
[NCBI:1269222]
[REACTOME:R-HSA-936964]
[PUBMED:15210742]
[PUBMED:14679297]
[PUBMED:15502848]
[PUBMED:17332413]
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Adipocytokine signaling pathway
[NCBI:83093]
[KEGG:hsa04920]
[PUBMED:12829246]
[PUBMED:10905472]
[PUBMED:15980064]
[PUBMED:12754525]
[PUBMED:12368907]
[PUBMED:11557972]
[PUBMED:15856064]
[PUBMED:9671776]
[PUBMED:10766253]
[PUBMED:15733744]
[PUBMED:15058305]
[PUBMED:14716305]
[PUBMED:11479627]
[PUBMED:14679176]
Angiopoietin receptor Tie2-mediated signaling
[NCBI:137917]
[Pathway Interaction Database:angiopoietinreceptor_pathway]
[PUBMED:9204896]
[PUBMED:12609966]
[PUBMED:14726409]
[PUBMED:11157678]
[PUBMED:10347092]
[PUBMED:11967990]
[PUBMED:15162796]
[PUBMED:11289054]
[PUBMED:12759249]
[PUBMED:10051567]
[PUBMED:12824293]
[PUBMED:16895971]
[PUBMED:10807867]
[PUBMED:12933576]
[PUBMED:11513602]
[PUBMED:12074640]
[PUBMED:8980223]
[PUBMED:14665640]
[PUBMED:15132996]
[PUBMED:10944458]
[PUBMED:11230987]
[PUBMED:15242771]
[PUBMED:10585289]
[PUBMED:16061664]
[PUBMED:10376602]
[PUBMED:15350545]
[PUBMED:9632797]
[PUBMED:10625301]
[PUBMED:9926914]
[PUBMED:17189382]
[PUBMED:11139469]
[PUBMED:11689432]
[PUBMED:11416142]
[PUBMED:11166279]
[PUBMED:15284220]
[PUBMED:15985432]
[PUBMED:16049136]
[PUBMED:16157706]
[PUBMED:10521483]
[PUBMED:12816861]
[PUBMED:9478921]
[PUBMED:10376603]
[PUBMED:15769741]
[PUBMED:12890486]
[PUBMED:14749497]
[PUBMED:7561682]
[PUBMED:11801735]
[PUBMED:12665569]
[PUBMED:12117724]
[PUBMED:9764820]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
CTLA4 inhibitory signaling
[NCBI:1269181]
[REACTOME:R-HSA-389513]
[PUBMED:11905831]
[PUBMED:10374692]
[PUBMED:16551244]
[PUBMED:12876557]
CXCR4-mediated signaling events
[NCBI:137910]
[Pathway Interaction Database:cxcr4_pathway]
[PUBMED:18799424]
[PUBMED:17537990]
[PUBMED:10881171]
[PUBMED:17675482]
[PUBMED:11157475]
[PUBMED:12077227]
[PUBMED:11544290]
[PUBMED:8752280]
[PUBMED:12535795]
[PUBMED:19380820]
[PUBMED:10952719]
[PUBMED:16230460]
[PUBMED:12682230]
[PUBMED:16503409]
[PUBMED:10644702]
[PUBMED:9722546]
[PUBMED:11784854]
[PUBMED:10491003]
[PUBMED:10521508]
[PUBMED:10606629]
[PUBMED:15615703]
[PUBMED:17568820]
[PUBMED:10753828]
[PUBMED:12519755]
[PUBMED:12032308]
[PUBMED:8752281]
[PUBMED:10570282]
[PUBMED:11369622]
[PUBMED:15728464]
[PUBMED:12590707]
[PUBMED:16038794]
[PUBMED:14662753]
[PUBMED:18596232]
[PUBMED:17056591]
[PUBMED:14602072]
[PUBMED:15994292]
[PUBMED:16919488]
[PUBMED:15872091]
[PUBMED:10506573]
[PUBMED:12036857]
[PUBMED:15618472]
[PUBMED:14704365]
[PUBMED:18227351]
[PUBMED:11641392]
[PUBMED:18319399]
[PUBMED:12133960]
[PUBMED:15630457]
Cell surface interactions at the vascular wall
[NCBI:1269373]
[REACTOME:R-HSA-202733]
[PUBMED:17525755]
[PUBMED:11282294]
[PUBMED:10798271]
[PUBMED:8578462]
[PUBMED:14615387]
[PUBMED:16115029]
Cell-Cell communication
[NCBI:1270231]
[REACTOME:R-HSA-1500931]
[PUBMED:20554646]
[PUBMED:12598678]
[PUBMED:17766183]
[PUBMED:18837673]
[PUBMED:16691243]
[PUBMED:1616050]
Chronic myeloid leukemia
[NCBI:83116]
[KEGG:hsa05220]
[PUBMED:22286129]
[PUBMED:12801837]
[PUBMED:11160144]
[PUBMED:15719031]
[PUBMED:10403855]
[PUBMED:9834202]
[PUBMED:11071626]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16484590]
[PUBMED:14982876]
Constitutive Signaling by Aberrant PI3K in Cancer
[NCBI:1268880]
[REACTOME:R-HSA-2219530]
[PUBMED:18317450]
[PUBMED:19962665]
[PUBMED:20009532]
[PUBMED:20713702]
[PUBMED:21478295]
[PUBMED:16339315]
[PUBMED:18079394]
[PUBMED:17626883]
Costimulation by the CD28 family
[NCBI:1269177]
[REACTOME:R-HSA-388841]
[PUBMED:10374692]
[PUBMED:14647476]
[PUBMED:11905831]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
DAP12 interactions
[NCBI:1269283]
[REACTOME:R-HSA-2172127]
[PUBMED:19120482]
[PUBMED:17220916]
[PUBMED:9490415]
[PUBMED:18192027]
[PUBMED:15884055]
DAP12 signaling
[NCBI:1269284]
[REACTOME:R-HSA-2424491]
[PUBMED:15884055]
[PUBMED:17110943]
[PUBMED:17220916]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
Downstream signal transduction
[NCBI:1269479]
[REACTOME:R-HSA-186763]
[PUBMED:10508235]
[PUBMED:9739761]
Downstream signaling events of B Cell Receptor (BCR)
[NCBI:1269185]
[REACTOME:R-HSA-1168372]
[PUBMED:17052215]
[PUBMED:19909372]
Downstream signaling of activated FGFR1
[NCBI:1269392]
[REACTOME:R-HSA-5654687]
[PUBMED:8752212]
Downstream signaling of activated FGFR2
[NCBI:1269403]
[REACTOME:R-HSA-5654696]
[PUBMED:8752212]
Downstream signaling of activated FGFR3
[NCBI:1269413]
[REACTOME:R-HSA-5654708]
[PUBMED:8752212]
Downstream signaling of activated FGFR4
[NCBI:1269422]
[REACTOME:R-HSA-5654716]
[PUBMED:8752212]
EGF receptor (ErbB1) signaling pathway
[NCBI:137970]
[Pathway Interaction Database:erbb1_receptor_proximal_pathway]
[PUBMED:15284024]
[PUBMED:15574420]
[PUBMED:12024020]
[PUBMED:10913131]
[PUBMED:2176151]
[PUBMED:8479540]
[PUBMED:8386805]
[PUBMED:10648629]
[PUBMED:7478566]
[PUBMED:9307968]
[PUBMED:6090944]
[PUBMED:1850098]
[PUBMED:7970708]
[PUBMED:12522133]
[PUBMED:1537335]
[PUBMED:10075741]
[PUBMED:9454735]
[PUBMED:9049300]
[PUBMED:9642214]
[PUBMED:14560030]
[PUBMED:9079708]
[PUBMED:12952932]
[PUBMED:10806474]
[PUBMED:1689011]
[PUBMED:7681824]
[PUBMED:9038217]
[PUBMED:7525285]
[PUBMED:14963038]
[PUBMED:7592690]
[PUBMED:1860884]
[PUBMED:19401591]
[PUBMED:12464621]
[PUBMED:8596638]
[PUBMED:7478553]
[PUBMED:8626525]
[PUBMED:8479541]
[PUBMED:7962064]
[PUBMED:10675331]
[PUBMED:8106552]
[PUBMED:9989831]
[PUBMED:10816576]
[PUBMED:7527043]
[PUBMED:2171993]
[PUBMED:12424235]
[PUBMED:7923364]
[PUBMED:2173144]
[PUBMED:7993895]
[PUBMED:8034616]
[PUBMED:9733788]
[PUBMED:2153914]
[PUBMED:1322798]
[PUBMED:14498832]
[PUBMED:8621459]
[PUBMED:7898933]
[PUBMED:9121432]
[PUBMED:11950594]
[PUBMED:7673163]
[PUBMED:7689150]
[PUBMED:1623525]
[PUBMED:8824201]
[PUBMED:8798379]
[PUBMED:8707848]
[PUBMED:15550174]
[PUBMED:8940013]
[PUBMED:10669730]
[PUBMED:8479536]
[PUBMED:17635937]
[PUBMED:18269246]
[PUBMED:10411909]
[PUBMED:7542246]
[PUBMED:7488034]
[PUBMED:2005883]
[PUBMED:1689310]
[PUBMED:7823926]
[PUBMED:16055672]
[PUBMED:2236073]
[PUBMED:8490966]
[PUBMED:18156174]
[PUBMED:8628261]
[PUBMED:8816994]
[PUBMED:8895577]
[PUBMED:11134009]
[PUBMED:9355745]
[PUBMED:1315766]
[PUBMED:1700866]
[PUBMED:9346957]
[PUBMED:7518560]
EPO signaling pathway
[NCBI:138051]
[Pathway Interaction Database:epopathway]
[PUBMED:14699131]
[PUBMED:7889566]
[PUBMED:8537396]
[PUBMED:11124936]
[PUBMED:9344843]
[PUBMED:12504103]
[PUBMED:7528577]
[PUBMED:15329338]
[PUBMED:15254422]
[PUBMED:7537740]
[PUBMED:9334184]
[PUBMED:10882725]
[PUBMED:15007095]
[PUBMED:15705783]
[PUBMED:10910907]
[PUBMED:8343951]
[PUBMED:8034732]
Epithelial cell signaling in Helicobacter pylori infection
[NCBI:83102]
[KEGG:hsa05120]
[PUBMED:11389469]
[PUBMED:15694859]
[PUBMED:14700549]
[PUBMED:12197905]
ErbB2/ErbB3 signaling events
[NCBI:137955]
[Pathway Interaction Database:erbb2erbb3pathway]
[PUBMED:9677338]
[PUBMED:11546794]
[PUBMED:9710588]
[PUBMED:11984589]
[PUBMED:19474313]
[PUBMED:12072561]
[PUBMED:18760695]
[PUBMED:18614687]
[PUBMED:11027222]
[PUBMED:12466964]
[PUBMED:10704452]
[PUBMED:19535578]
[PUBMED:7556067]
[PUBMED:16481445]
[PUBMED:10493750]
[PUBMED:17998937]
[PUBMED:17210635]
[PUBMED:18799465]
[PUBMED:12411582]
[PUBMED:15520002]
[PUBMED:10531446]
[PUBMED:10101228]
[PUBMED:10399934]
[PUBMED:8815893]
[PUBMED:19179536]
[PUBMED:7877996]
[PUBMED:11173924]
[PUBMED:12651161]
[PUBMED:9362461]
[PUBMED:18426980]
[PUBMED:19019207]
[PUBMED:9338783]
[PUBMED:11312610]
[PUBMED:11940572]
[PUBMED:8707830]
[PUBMED:11564761]
[PUBMED:9049301]
[PUBMED:9694850]
[PUBMED:10582594]
[PUBMED:9637684]
[PUBMED:8702681]
FGF signaling pathway
[NCBI:137989]
[Pathway Interaction Database:fgf_pathway]
[PUBMED:12419216]
[PUBMED:16775459]
[PUBMED:1656221]
[PUBMED:16857743]
[PUBMED:8707855]
[PUBMED:17545628]
[PUBMED:17623664]
[PUBMED:16893902]
[PUBMED:15105428]
[PUBMED:16436388]
[PUBMED:12370824]
[PUBMED:9707175]
[PUBMED:1380001]
[PUBMED:15569927]
[PUBMED:11241670]
[PUBMED:11433297]
[PUBMED:16709412]
[PUBMED:12815057]
[PUBMED:14966081]
[PUBMED:17086194]
[PUBMED:17311277]
[PUBMED:14534538]
[PUBMED:12398894]
[PUBMED:8940113]
[PUBMED:17266935]
[PUBMED:10652257]
[PUBMED:12604616]
[PUBMED:14666721]
[PUBMED:9045692]
[PUBMED:15509650]
[PUBMED:11353842]
[PUBMED:12791257]
[PUBMED:15564375]
[PUBMED:12529371]
[PUBMED:17409417]
[PUBMED:17005551]
[PUBMED:12815619]
[PUBMED:11997436]
[PUBMED:12110689]
[PUBMED:17627937]
FRS-mediated FGFR1 signaling
[NCBI:1269393]
[REACTOME:R-HSA-5654693]
[PUBMED:15863030]
[PUBMED:18452557]
[PUBMED:11447289]
[PUBMED:16682955]
FRS-mediated FGFR2 signaling
[NCBI:1269404]
[REACTOME:R-HSA-5654700]
[PUBMED:18452557]
[PUBMED:11447289]
[PUBMED:16682955]
[PUBMED:15863030]
FRS-mediated FGFR3 signaling
[NCBI:1269414]
[REACTOME:R-HSA-5654706]
[PUBMED:15863030]
[PUBMED:18452557]
[PUBMED:11447289]
[PUBMED:16682955]
FRS-mediated FGFR4 signaling
[NCBI:1269423]
[REACTOME:R-HSA-5654712]
[PUBMED:18452557]
[PUBMED:11447289]
[PUBMED:16682955]
[PUBMED:15863030]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Fc-epsilon receptor I signaling in mast cells
[NCBI:138050]
[Pathway Interaction Database:fcer1pathway]
[PUBMED:9556577]
[PUBMED:8629002]
[PUBMED:12217401]
[PUBMED:15010370]
[PUBMED:15608142]
[PUBMED:7561053]
[PUBMED:7537741]
[PUBMED:7963537]
[PUBMED:8947047]
[PUBMED:1384468]
[PUBMED:14757742]
[PUBMED:16174756]
[PUBMED:10583594]
[PUBMED:7513150]
[PUBMED:12089510]
[PUBMED:10811803]
[PUBMED:9268346]
[PUBMED:12640123]
[PUBMED:9108083]
[PUBMED:8602265]
[PUBMED:11340169]
[PUBMED:12953098]
[PUBMED:11465115]
[PUBMED:7730640]
[PUBMED:9550384]
[PUBMED:7518558]
[PUBMED:11137136]
[PUBMED:15282299]
[PUBMED:14634134]
[PUBMED:8534912]
[PUBMED:16002993]
[PUBMED:12192036]
[PUBMED:7608202]
[PUBMED:11714805]
[PUBMED:11970986]
[PUBMED:10903718]
[PUBMED:15265912]
[PUBMED:15477350]
GAB1 signalosome
[NCBI:1269384]
[REACTOME:R-HSA-180292]
[PUBMED:15550174]
GPVI-mediated activation cascade
[NCBI:1269357]
[REACTOME:R-HSA-114604]
[PUBMED:16102042]
[PUBMED:11943772]
Hemostasis
[NCBI:1269340]
[REACTOME:R-HSA-109582]
Herpes simplex infection
[NCBI:377873]
[KEGG:hsa05168]
[PUBMED:12224518]
[PUBMED:17913820]
[PUBMED:12844494]
[PUBMED:10998601]
[PUBMED:15163721]
[PUBMED:19694546]
[PUBMED:16297150]
[PUBMED:14747533]
[PUBMED:12826401]
[PUBMED:14963113]
[PUBMED:15056211]
[PUBMED:12797447]
[PUBMED:21107701]
[PUBMED:10918307]
[PUBMED:10696424]
[PUBMED:16076403]
[PUBMED:10364308]
[PUBMED:17222692]
[PUBMED:9621021]
[PUBMED:12224508]
[PUBMED:19879619]
[PUBMED:11070032]
[PUBMED:9499021]
[PUBMED:18596690]
[PUBMED:12525427]
[PUBMED:12224517]
[PUBMED:10196275]
[PUBMED:15047834]
[PUBMED:18508584]
[PUBMED:20036979]
IFN-gamma pathway
[NCBI:138040]
[Pathway Interaction Database:ifngpathway]
[PUBMED:9724754]
[PUBMED:10657627]
[PUBMED:10067896]
[PUBMED:9271410]
[PUBMED:8608598]
[PUBMED:15878863]
[PUBMED:11971965]
[PUBMED:11438544]
[PUBMED:15051500]
[PUBMED:17032168]
[PUBMED:11909529]
[PUBMED:11171987]
[PUBMED:7514165]
[PUBMED:12817007]
[PUBMED:8232552]
[PUBMED:10485906]
[PUBMED:8755534]
[PUBMED:10490100]
[PUBMED:8156998]
[PUBMED:11972023]
[PUBMED:8986769]
[PUBMED:12438563]
[PUBMED:10022928]
[PUBMED:12270932]
[PUBMED:7510216]
[PUBMED:15311277]
[PUBMED:14670297]
[PUBMED:12048245]
[PUBMED:10777554]
[PUBMED:12138178]
[PUBMED:9336467]
[PUBMED:7690989]
[PUBMED:1281555]
[PUBMED:17606919]
[PUBMED:10805787]
[PUBMED:12050152]
[PUBMED:8608597]
[PUBMED:15879117]
[PUBMED:12855578]
[PUBMED:10995751]
[PUBMED:10490099]
[PUBMED:7777519]
IGF1 pathway
[NCBI:137992]
[Pathway Interaction Database:igf1_pathway]
[PUBMED:15003536]
[PUBMED:10576742]
[PUBMED:8621590]
[PUBMED:9346240]
[PUBMED:16932738]
[PUBMED:8662827]
[PUBMED:15976035]
[PUBMED:11572799]
[PUBMED:14550766]
[PUBMED:15070696]
[PUBMED:9346905]
[PUBMED:10490655]
[PUBMED:1378290]
[PUBMED:9480911]
[PUBMED:9442079]
[PUBMED:7534289]
[PUBMED:8265614]
[PUBMED:9748296]
[PUBMED:11884618]
[PUBMED:12538620]
[PUBMED:8798417]
[PUBMED:8764099]
[PUBMED:8505282]
[PUBMED:7540132]
[PUBMED:12048182]
[PUBMED:15611085]
[PUBMED:14604996]
[PUBMED:7642582]
[PUBMED:11836447]
[PUBMED:8776723]
[PUBMED:7513703]
[PUBMED:9506989]
IGF1R signaling cascade
[NCBI:1269618]
[REACTOME:R-HSA-2428924]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
IL2 signaling events mediated by PI3K
[NCBI:137938]
[Pathway Interaction Database:il2_pi3kpathway]
[PUBMED:15271800]
[PUBMED:8617294]
[PUBMED:7543780]
[PUBMED:9092570]
[PUBMED:9162082]
[PUBMED:7737351]
[PUBMED:9108028]
[PUBMED:11486019]
[PUBMED:1614535]
[PUBMED:15843522]
[PUBMED:7760801]
[PUBMED:9029085]
[PUBMED:1652056]
[PUBMED:11994454]
[PUBMED:12393431]
[PUBMED:9771966]
[PUBMED:10373522]
[PUBMED:12525482]
[PUBMED:3523754]
[PUBMED:7736574]
[PUBMED:10982827]
[PUBMED:7589144]
[PUBMED:7528328]
IL2 signaling events mediated by STAT5
[NCBI:137988]
[Pathway Interaction Database:il2_stat5pathway]
[PUBMED:11160217]
[PUBMED:16645171]
[PUBMED:9121484]
[PUBMED:17182565]
[PUBMED:14607901]
[PUBMED:9104808]
[PUBMED:11485747]
[PUBMED:14614860]
[PUBMED:10679091]
[PUBMED:12196288]
[PUBMED:10072077]
[PUBMED:10544201]
[PUBMED:15004274]
[PUBMED:9390691]
[PUBMED:9395528]
[PUBMED:10514006]
[PUBMED:14500638]
[PUBMED:16757175]
[PUBMED:9541574]
[PUBMED:8617294]
IL2-mediated signaling events
[NCBI:137976]
[Pathway Interaction Database:il2_1pathway]
[PUBMED:7568005]
[PUBMED:10962026]
[PUBMED:1545122]
[PUBMED:10602027]
[PUBMED:15170389]
[PUBMED:9092570]
[PUBMED:7509794]
[PUBMED:15356145]
[PUBMED:9973481]
[PUBMED:10899310]
[PUBMED:9195132]
[PUBMED:7544001]
[PUBMED:7777534]
[PUBMED:12681450]
[PUBMED:7665592]
[PUBMED:8702919]
[PUBMED:1708096]
[PUBMED:8643566]
[PUBMED:7988557]
[PUBMED:7737351]
[PUBMED:1532814]
[PUBMED:8262551]
[PUBMED:8025955]
[PUBMED:10993906]
[PUBMED:3095922]
[PUBMED:8805624]
[PUBMED:9391116]
[PUBMED:7973658]
[PUBMED:11331873]
[PUBMED:10421845]
[PUBMED:8119884]
[PUBMED:7781605]
[PUBMED:12543077]
[PUBMED:9133424]
[PUBMED:1618313]
[PUBMED:1940342]
[PUBMED:9382798]
[PUBMED:10514520]
[PUBMED:7973659]
[PUBMED:1639773]
[PUBMED:9029085]
[PUBMED:7760801]
[PUBMED:1460037]
[PUBMED:9202126]
[PUBMED:1652056]
[PUBMED:12393431]
[PUBMED:8397196]
[PUBMED:2047859]
[PUBMED:7688728]
[PUBMED:8700888]
[PUBMED:7528668]
[PUBMED:9305919]
[PUBMED:2303462]
[PUBMED:7568001]
[PUBMED:9822600]
[PUBMED:7543676]
[PUBMED:7499365]
[PUBMED:10843677]
[PUBMED:7600304]
[PUBMED:7719937]
[PUBMED:9590209]
[PUBMED:9794391]
[PUBMED:10849428]
[PUBMED:8294403]
[PUBMED:10373548]
[PUBMED:2590941]
[PUBMED:9512511]
[PUBMED:6434688]
[PUBMED:9697832]
[PUBMED:10982827]
[PUBMED:10214954]
[PUBMED:10825200]
[PUBMED:1535827]
[PUBMED:10369681]
[PUBMED:7719938]
[PUBMED:1655887]
[PUBMED:8376945]
[PUBMED:1996324]
[PUBMED:7479881]
[PUBMED:10962581]
[PUBMED:7973657]
[PUBMED:1631559]
[PUBMED:10066828]
[PUBMED:9169478]
[PUBMED:8552611]
[PUBMED:8483935]
[PUBMED:2106566]
[PUBMED:16199887]
IL6-mediated signaling events
[NCBI:137932]
[Pathway Interaction Database:il6_7pathway]
[PUBMED:8559663]
[PUBMED:8662591]
[PUBMED:11689697]
[PUBMED:11727828]
[PUBMED:10383440]
[PUBMED:10777583]
[PUBMED:16774741]
[PUBMED:12754507]
[PUBMED:9295319]
[PUBMED:15722452]
[PUBMED:10859312]
[PUBMED:9590172]
[PUBMED:9880505]
[PUBMED:12445202]
[PUBMED:8134389]
[PUBMED:10409724]
[PUBMED:8164674]
[PUBMED:8272872]
[PUBMED:9794795]
[PUBMED:7678052]
[PUBMED:8511589]
[PUBMED:8668165]
[PUBMED:9724754]
[PUBMED:8083235]
[PUBMED:12754505]
[PUBMED:8621622]
[PUBMED:16254248]
[PUBMED:12361954]
[PUBMED:10605021]
[PUBMED:9388184]
[PUBMED:15935617]
[PUBMED:11120832]
[PUBMED:7875298]
[PUBMED:9973404]
[PUBMED:11335711]
[PUBMED:9632795]
[PUBMED:11468294]
[PUBMED:7898939]
[PUBMED:8626374]
[PUBMED:8670868]
[PUBMED:7537214]
[PUBMED:15677447]
[PUBMED:2261637]
[PUBMED:9874564]
[PUBMED:12829785]
[PUBMED:8537375]
[PUBMED:8272873]
[PUBMED:7523403]
[PUBMED:11251120]
[PUBMED:9163525]
[PUBMED:3136546]
[PUBMED:10727406]
[PUBMED:10023775]
[PUBMED:12754506]
[PUBMED:12456685]
[PUBMED:2788034]
[PUBMED:10446219]
[PUBMED:15572665]
[PUBMED:1662392]
[PUBMED:15010462]
[PUBMED:8140422]
[PUBMED:8467812]
IRS-mediated signalling
[NCBI:1269431]
[REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R
[NCBI:1269620]
[REACTOME:R-HSA-2428928]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:18927274]
[PUBMED:21042815]
[PUBMED:20098959]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Insulin Pathway
[NCBI:138026]
[Pathway Interaction Database:insulin_pathway]
[PUBMED:8491186]
[PUBMED:9111325]
[PUBMED:7629070]
[PUBMED:10499514]
[PUBMED:11121405]
[PUBMED:10660596]
[PUBMED:8196603]
[PUBMED:11096081]
[PUBMED:8524328]
[PUBMED:9891043]
[PUBMED:12242347]
[PUBMED:2123524]
[PUBMED:9369444]
[PUBMED:1375946]
[PUBMED:9348199]
[PUBMED:8826975]
[PUBMED:8316835]
[PUBMED:8999839]
[PUBMED:8449939]
[PUBMED:10807907]
[PUBMED:1599438]
[PUBMED:8265614]
[PUBMED:11171109]
[PUBMED:11821390]
[PUBMED:12687004]
[PUBMED:7806540]
[PUBMED:11154281]
[PUBMED:8244979]
[PUBMED:8798417]
[PUBMED:1381348]
[PUBMED:7581368]
[PUBMED:15787604]
[PUBMED:8385105]
[PUBMED:11551902]
[PUBMED:8114695]
[PUBMED:11997497]
[PUBMED:11001060]
[PUBMED:11309621]
[PUBMED:9109420]
[PUBMED:8383963]
[PUBMED:12147684]
[PUBMED:8144662]
[PUBMED:12036959]
[PUBMED:14734537]
[PUBMED:7983051]
[PUBMED:9083103]
[PUBMED:15210700]
[PUBMED:9065430]
[PUBMED:11297536]
[PUBMED:10544179]
[PUBMED:1321126]
[PUBMED:11502760]
[PUBMED:8978681]
[PUBMED:8999972]
[PUBMED:14690593]
[PUBMED:11832334]
[PUBMED:9447983]
[PUBMED:15192089]
[PUBMED:8524413]
[PUBMED:7685165]
[PUBMED:10329736]
[PUBMED:11287630]
[PUBMED:15486046]
[PUBMED:10330191]
[PUBMED:8626723]
Insulin receptor signalling cascade
[NCBI:1269429]
[REACTOME:R-HSA-74751]
[PUBMED:9677303]
[PUBMED:11282018]
Insulin resistance
[NCBI:1272486]
[KEGG:hsa04931]
[PUBMED:17130651]
[PUBMED:20466550]
[PUBMED:16364488]
[PUBMED:12765939]
[PUBMED:15166380]
[PUBMED:7666792]
[PUBMED:16756496]
[PUBMED:23647930]
[PUBMED:10923637]
[PUBMED:17141630]
[PUBMED:9886945]
[PUBMED:8048519]
[PUBMED:18309108]
[PUBMED:15107844]
[PUBMED:20526383]
[PUBMED:22360800]
[PUBMED:16186396]
[PUBMED:22675355]
[PUBMED:22677645]
Integrins in angiogenesis
[NCBI:137999]
[Pathway Interaction Database:avb3_integrin_pathway]
[PUBMED:10837460]
[PUBMED:9182576]
[PUBMED:12642872]
[PUBMED:15711558]
[PUBMED:10037797]
[PUBMED:10196194]
[PUBMED:11877390]
[PUBMED:16418218]
[PUBMED:16600665]
[PUBMED:16982628]
[PUBMED:15479743]
[PUBMED:16720645]
[PUBMED:11684710]
[PUBMED:10821695]
[PUBMED:12237112]
[PUBMED:12750158]
[PUBMED:11551924]
[PUBMED:8794870]
[PUBMED:10022831]
[PUBMED:15187087]
[PUBMED:16195423]
[PUBMED:16760434]
[PUBMED:12682293]
[PUBMED:9420328]
[PUBMED:15247219]
[PUBMED:9490736]
[PUBMED:11313365]
Interferon Signaling
[NCBI:1269311]
[REACTOME:R-HSA-913531]
[PUBMED:18929502]
[PUBMED:15607020]
[PUBMED:15864272]
[PUBMED:14525967]
[PUBMED:19059436]
Interferon alpha/beta signaling
[NCBI:1269312]
[REACTOME:R-HSA-909733]
[PUBMED:8621447]
[PUBMED:8605876]
[PUBMED:8702790]
[PUBMED:17969444]
Interferon gamma signaling
[NCBI:1269314]
[REACTOME:R-HSA-877300]
[PUBMED:9462485]
[PUBMED:18929502]
[PUBMED:9143700]
[PUBMED:14525967]
Interleukin-3, 5 and GM-CSF signaling
[NCBI:1269323]
[REACTOME:R-HSA-512988]
[PUBMED:10450743]
[PUBMED:9766809]
Interleukin-6 family signaling
[NCBI:1339142]
[REACTOME:R-HSA-6783589]
[PUBMED:9685167]
[PUBMED:8666978]
[PUBMED:12773095]
[PUBMED:9143707]
[PUBMED:9716487]
[PUBMED:7632928]
Interleukin-6 signaling
[NCBI:1269325]
[REACTOME:R-HSA-1059683]
[PUBMED:20410258]
Jak-STAT signaling pathway
[NCBI:83077]
[KEGG:hsa04630]
[PUBMED:21034406]
[PUBMED:22339650]
[PUBMED:16204702]
[PUBMED:25587654]
[PUBMED:24069565]
[PUBMED:22383755]
[PUBMED:24606160]
[PUBMED:10851053]
[PUBMED:23735217]
[PUBMED:25217450]
[PUBMED:21372217]
Leukocyte transendothelial migration
[NCBI:83083]
[KEGG:hsa04670]
[PUBMED:15629883]
[PUBMED:10975856]
[PUBMED:14976004]
[PUBMED:15265790]
[PUBMED:15173832]
[PUBMED:12540948]
[PUBMED:15771581]
[PUBMED:15604886]
[PUBMED:14977592]
MAPK family signaling cascades
[NCBI:1269501]
[REACTOME:R-HSA-5683057]
[PUBMED:21167873]
[PUBMED:17161475]
[PUBMED:22535895]
[PUBMED:21372320]
MAPK1 (ERK2) activation
[NCBI:1269505]
[REACTOME:R-HSA-112411]
[PUBMED:22177953]
[PUBMED:8131746]
MAPK1/MAPK3 signaling
[NCBI:1269502]
[REACTOME:R-HSA-5684996]
[PUBMED:25378393]
[PUBMED:18199641]
[PUBMED:17496909]
[PUBMED:21779496]
[PUBMED:15520807]
[PUBMED:16393692]
[PUBMED:19520853]
[PUBMED:17496910]
[PUBMED:22569528]
MAPK3 (ERK1) activation
[NCBI:1269504]
[REACTOME:R-HSA-110056]
MET activates PTPN11
[NCBI:1457798]
[REACTOME:R-HSA-8865999]
[PUBMED:10871282]
[PUBMED:24951116]
[PUBMED:16765027]
MyD88-independent TLR3/TLR4 cascade
[NCBI:1269220]
[REACTOME:R-HSA-166166]
[PUBMED:15276183]
NGF signalling via TRKA from the plasma membrane
[NCBI:1269460]
[REACTOME:R-HSA-187037]
[PUBMED:11520933]
[PUBMED:12676795]
[PUBMED:10851172]
[PUBMED:10579918]
Natural killer cell mediated cytotoxicity
[NCBI:83079]
[KEGG:hsa04650]
[PUBMED:12530970]
[PUBMED:15567854]
[PUBMED:8942070]
[PUBMED:11905813]
[PUBMED:9143705]
[PUBMED:9862693]
[PUBMED:11895890]
[PUBMED:12205470]
[PUBMED:11836514]
[PUBMED:15607806]
[PUBMED:16002670]
[PUBMED:15618404]
[PUBMED:11390470]
[PUBMED:11062493]
[PUBMED:14710949]
[PUBMED:12752668]
[PUBMED:15607802]
[PUBMED:16109839]
[PUBMED:12766758]
[PUBMED:16177799]
Negative regulation of FGFR1 signaling
[NCBI:1269397]
[REACTOME:R-HSA-5654726]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
[PUBMED:12815057]
Negative regulation of FGFR2 signaling
[NCBI:1269408]
[REACTOME:R-HSA-5654727]
[PUBMED:12815057]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
Negative regulation of FGFR3 signaling
[NCBI:1269418]
[REACTOME:R-HSA-5654732]
[PUBMED:12815057]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
Negative regulation of FGFR4 signaling
[NCBI:1269427]
[REACTOME:R-HSA-5654733]
[PUBMED:12815057]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
Negative regulation of the PI3K/AKT network
[NCBI:1269191]
[REACTOME:R-HSA-199418]
Netrin mediated repulsion signals
[NCBI:1270316]
[REACTOME:R-HSA-418886]
Netrin-1 signaling
[NCBI:1270314]
[REACTOME:R-HSA-373752]
[PUBMED:18269208]
[PUBMED:10499167]
Neurotrophic factor-mediated Trk receptor signaling
[NCBI:137977]
[Pathway Interaction Database:trkrpathway]
[PUBMED:1849459]
[PUBMED:8226808]
[PUBMED:11163269]
[PUBMED:7510697]
[PUBMED:11027277]
[PUBMED:15758069]
[PUBMED:11425862]
[PUBMED:11238898]
[PUBMED:11251075]
[PUBMED:8344249]
[PUBMED:9356464]
[PUBMED:11150291]
[PUBMED:10092678]
[PUBMED:1280261]
[PUBMED:11150334]
[PUBMED:11244088]
[PUBMED:10985348]
[PUBMED:15753086]
[PUBMED:1653651]
[PUBMED:11466412]
[PUBMED:15167895]
[PUBMED:1831195]
[PUBMED:10490030]
[PUBMED:8384556]
[PUBMED:16697063]
[PUBMED:17003042]
[PUBMED:15520226]
[PUBMED:15632082]
[PUBMED:16611639]
[PUBMED:16187212]
[PUBMED:9182757]
[PUBMED:1604323]
[PUBMED:16284401]
[PUBMED:8356095]
[PUBMED:10329710]
[PUBMED:9927421]
[PUBMED:9856458]
[PUBMED:10691301]
[PUBMED:1375038]
[PUBMED:10679771]
[PUBMED:15122257]
[PUBMED:15513915]
[PUBMED:16701206]
[PUBMED:1710174]
[PUBMED:8155326]
[PUBMED:8288573]
[PUBMED:7972023]
[PUBMED:7512734]
[PUBMED:10601297]
[PUBMED:16203995]
[PUBMED:12510192]
[PUBMED:16481401]
[PUBMED:8106527]
[PUBMED:11278445]
[PUBMED:9099755]
[PUBMED:1850821]
[PUBMED:9632781]
[PUBMED:10235685]
[PUBMED:15917464]
[PUBMED:9285826]
[PUBMED:12446789]
[PUBMED:7657612]
[PUBMED:1850549]
[PUBMED:12879077]
[PUBMED:16157584]
[PUBMED:10207144]
[PUBMED:12006576]
[PUBMED:8052307]
[PUBMED:8382740]
[PUBMED:10629055]
Neurotrophin signaling pathway
[NCBI:101143]
[KEGG:hsa04722]
[PUBMED:16699811]
[PUBMED:10812966]
[PUBMED:12676795]
[PUBMED:16939974]
[PUBMED:10851172]
[PUBMED:15499580]
[PUBMED:14704852]
[PUBMED:11399424]
[PUBMED:10764727]
[PUBMED:10985348]
[PUBMED:16856873]
[PUBMED:11529497]
PD-1 signaling
[NCBI:1269182]
[REACTOME:R-HSA-389948]
[PUBMED:18759926]
[PUBMED:18173375]
PDGFR-beta signaling pathway
[NCBI:138071]
[Pathway Interaction Database:pdgfrbpathway]
[PUBMED:7545675]
[PUBMED:16769879]
[PUBMED:12652307]
[PUBMED:10463951]
[PUBMED:9742401]
[PUBMED:8086421]
[PUBMED:10391677]
[PUBMED:7739538]
[PUBMED:9989826]
[PUBMED:10734138]
[PUBMED:15753096]
[PUBMED:7692233]
[PUBMED:11489946]
[PUBMED:10837138]
[PUBMED:10229199]
[PUBMED:10821867]
[PUBMED:11709084]
[PUBMED:11389443]
[PUBMED:12958184]
[PUBMED:10734113]
[PUBMED:15161943]
[PUBMED:12149261]
[PUBMED:16456542]
[PUBMED:16224065]
[PUBMED:8619809]
[PUBMED:15494217]
[PUBMED:1849073]
[PUBMED:11085978]
[PUBMED:2544881]
[PUBMED:7622571]
[PUBMED:10779329]
[PUBMED:15944146]
[PUBMED:11027258]
[PUBMED:1708307]
[PUBMED:8940081]
[PUBMED:11854295]
[PUBMED:8195171]
[PUBMED:12424235]
[PUBMED:7935392]
[PUBMED:14966296]
[PUBMED:16537894]
PECAM1 interactions
[NCBI:1269375]
[REACTOME:R-HSA-210990]
[PUBMED:12681475]
[PUBMED:14619965]
PI-3K cascade:FGFR1
[NCBI:1269396]
[REACTOME:R-HSA-5654689]
[PUBMED:15863030]
[PUBMED:11057895]
[PUBMED:12089343]
[PUBMED:12558974]
[PUBMED:10918587]
PI-3K cascade:FGFR2
[NCBI:1269407]
[REACTOME:R-HSA-5654695]
[PUBMED:10918587]
[PUBMED:15863030]
[PUBMED:11057895]
[PUBMED:12558974]
[PUBMED:12089343]
PI-3K cascade:FGFR3
[NCBI:1269417]
[REACTOME:R-HSA-5654710]
[PUBMED:10918587]
[PUBMED:15863030]
[PUBMED:11057895]
[PUBMED:12089343]
[PUBMED:12558974]
PI-3K cascade:FGFR4
[NCBI:1269426]
[REACTOME:R-HSA-5654720]
[PUBMED:10918587]
[PUBMED:15863030]
[PUBMED:11057895]
[PUBMED:12558974]
[PUBMED:12089343]
PI3K Cascade
[NCBI:1269432]
[REACTOME:R-HSA-109704]
PI3K/AKT Signaling in Cancer
[NCBI:1268879]
[REACTOME:R-HSA-2219528]
[PUBMED:20713702]
[PUBMED:10555148]
[PUBMED:19644473]
[PUBMED:17611497]
[PUBMED:21478295]
[PUBMED:17626883]
[PUBMED:16339315]
[PUBMED:18317450]
[PUBMED:18079394]
[PUBMED:9467011]
[PUBMED:17604717]
[PUBMED:9326929]
[PUBMED:18954143]
[PUBMED:20009532]
[PUBMED:19962665]
[PUBMED:21430697]
[PUBMED:19487573]
[PUBMED:10866302]
PI3K/AKT activation
[NCBI:1269473]
[REACTOME:R-HSA-198203]
[PUBMED:10579926]
[PUBMED:12123609]
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
[NCBI:1383020]
[REACTOME:R-HSA-6811558]
[PUBMED:12422219]
[PUBMED:16979564]
[PUBMED:19805105]
[PUBMED:17200115]
[PUBMED:21827948]
[PUBMED:19576174]
[PUBMED:18753295]
[PUBMED:19896968]
[PUBMED:16456541]
[PUBMED:25495341]
[PUBMED:15464023]
[PUBMED:23758345]
[PUBMED:9367159]
[PUBMED:9211928]
[PUBMED:17245604]
PIP3 activates AKT signaling
[NCBI:1269188]
[REACTOME:R-HSA-1257604]
Phospholipase D signaling pathway
[NCBI:1311074]
[KEGG:hsa04072]
[PUBMED:9310372]
[PUBMED:9119890]
[PUBMED:15310762]
[PUBMED:18936782]
[PUBMED:24990952]
[PUBMED:14769825]
[PUBMED:21936578]
[PUBMED:10666319]
[PUBMED:17210675]
[PUBMED:19264150]
[PUBMED:23076158]
[PUBMED:17054901]
[PUBMED:16622417]
[PUBMED:10807766]
[PUBMED:12217395]
[PUBMED:11042115]
[PUBMED:19815110]
[PUBMED:24995811]
[PUBMED:16143829]
[PUBMED:8135758]
[PUBMED:11991733]
[PUBMED:19410013]
[PUBMED:17245604]
Platelet activation, signaling and aggregation
[NCBI:1269350]
[REACTOME:R-HSA-76002]
[PUBMED:16543958]
[PUBMED:8704248]
[PUBMED:2018971]
[PUBMED:1672265]
[PUBMED:17059469]
[PUBMED:12681240]
[PUBMED:12411949]
[PUBMED:11511514]
Platelet homeostasis
[NCBI:1269341]
[REACTOME:R-HSA-418346]
[PUBMED:10798271]
Platelet sensitization by LDL
[NCBI:1269348]
[REACTOME:R-HSA-432142]
[PUBMED:12038793]
[PUBMED:12775720]
[PUBMED:15459198]
Prolactin receptor signaling
[NCBI:1269328]
[REACTOME:R-HSA-1170546]
[PUBMED:9626554]
[PUBMED:11356125]
[PUBMED:11826263]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
RAF-independent MAPK1/3 activation
[NCBI:1269503]
[REACTOME:R-HSA-112409]
[PUBMED:21135874]
[PUBMED:22569528]
[PUBMED:23954936]
RET signaling
[NCBI:1427866]
[REACTOME:R-HSA-8853659]
[PUBMED:15013219]
[PUBMED:17036197]
Ras signaling pathway
[NCBI:868085]
[KEGG:hsa04014]
[PUBMED:23506953]
[PUBMED:18437264]
[PUBMED:15062121]
[PUBMED:22189424]
[PUBMED:22233291]
[PUBMED:12778136]
[PUBMED:11313946]
[PUBMED:17428555]
[PUBMED:19091743]
[PUBMED:18568040]
[PUBMED:20420946]
[PUBMED:12217381]
[PUBMED:14663478]
[PUBMED:21686117]
[PUBMED:12642680]
[PUBMED:21196257]
[PUBMED:16869784]
[PUBMED:21111786]
[PUBMED:16966426]
[PUBMED:10712923]
[PUBMED:22020205]
[PUBMED:17384584]
[PUBMED:15572660]
[PUBMED:18413813]
Regulation of IFNA signaling
[NCBI:1269313]
[REACTOME:R-HSA-912694]
[PUBMED:16710296]
[PUBMED:16311601]
[PUBMED:10526574]
Regulation of IFNG signaling
[NCBI:1269315]
[REACTOME:R-HSA-877312]
[PUBMED:10526574]
[PUBMED:18031232]
[PUBMED:12645661]
Renal cell carcinoma
[NCBI:83107]
[KEGG:hsa05211]
[PUBMED:12351585]
[PUBMED:17211469]
[PUBMED:16339096]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15611513]
[PUBMED:14685170]
[PUBMED:15122209]
Role of LAT2/NTAL/LAB on calcium mobilization
[NCBI:1269302]
[REACTOME:R-HSA-2730905]
[PUBMED:17993265]
[PUBMED:20643813]
[PUBMED:17420272]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signal regulatory protein (SIRP) family interactions
[NCBI:1270241]
[REACTOME:R-HSA-391160]
[PUBMED:16339511]
[PUBMED:11792697]
[PUBMED:16691243]
[PUBMED:12023008]
[PUBMED:19144521]
Signaling by EGFR
[NCBI:1269380]
[REACTOME:R-HSA-177929]
[PUBMED:10459005]
[PUBMED:10404636]
[PUBMED:12297041]
[PUBMED:15142631]
Signaling by FGFR
[NCBI:1269386]
[REACTOME:R-HSA-190236]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:20602996]
[PUBMED:15863030]
[PUBMED:15567848]
[PUBMED:7917292]
[PUBMED:19247306]
[PUBMED:16597617]
Signaling by FGFR1
[NCBI:1269387]
[REACTOME:R-HSA-5654736]
[PUBMED:16597617]
[PUBMED:19247306]
[PUBMED:12080084]
[PUBMED:15863038]
[PUBMED:15567848]
[PUBMED:20602996]
[PUBMED:7917292]
[PUBMED:15863030]
Signaling by FGFR2
[NCBI:1269399]
[REACTOME:R-HSA-5654738]
[PUBMED:19247306]
[PUBMED:16597617]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:15863030]
[PUBMED:20602996]
[PUBMED:15567848]
[PUBMED:7917292]
Signaling by FGFR3
[NCBI:1269409]
[REACTOME:R-HSA-5654741]
[PUBMED:16597617]
[PUBMED:19247306]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:20602996]
[PUBMED:15567848]
[PUBMED:7917292]
[PUBMED:15863030]
Signaling by FGFR4
[NCBI:1269419]
[REACTOME:R-HSA-5654743]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:15567848]
[PUBMED:20602996]
[PUBMED:7917292]
[PUBMED:15863030]
[PUBMED:19247306]
[PUBMED:16597617]
Signaling by Insulin receptor
[NCBI:1269428]
[REACTOME:R-HSA-74752]
[PUBMED:8276779]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Signaling by Leptin
[NCBI:1269632]
[REACTOME:R-HSA-2586552]
[PUBMED:22211890]
[PUBMED:23562747]
[PUBMED:20600241]
[PUBMED:21622208]
[PUBMED:23579596]
[PUBMED:22458591]
[PUBMED:21489811]
[PUBMED:19724019]
[PUBMED:21331644]
[PUBMED:22448029]
[PUBMED:21147620]
[PUBMED:20198122]
[PUBMED:21677426]
[PUBMED:20029269]
[PUBMED:22249808]
[PUBMED:22991412]
[PUBMED:21527729]
[PUBMED:17937601]
[PUBMED:20553370]
[PUBMED:21713385]
[PUBMED:23565489]
[PUBMED:22289780]
Signaling by MET
[NCBI:1457794]
[REACTOME:R-HSA-6806834]
[PUBMED:1846706]
[PUBMED:12948444]
[PUBMED:16782899]
[PUBMED:15249655]
[PUBMED:22270953]
[PUBMED:15167892]
[PUBMED:7708691]
[PUBMED:11081636]
[PUBMED:8384622]
[PUBMED:21102609]
[PUBMED:16461907]
[PUBMED:9407027]
[PUBMED:7854453]
[PUBMED:7651534]
[PUBMED:9070211]
[PUBMED:8208547]
[PUBMED:24518591]
[PUBMED:6590967]
[PUBMED:15180923]
[PUBMED:20802513]
[PUBMED:10521801]
[PUBMED:9038378]
[PUBMED:17403932]
[PUBMED:1655790]
[PUBMED:12006644]
[PUBMED:7513258]
[PUBMED:18614017]
[PUBMED:10753869]
[PUBMED:17662939]
[PUBMED:14685170]
[PUBMED:10734310]
[PUBMED:1827664]
[PUBMED:7731718]
[PUBMED:19996456]
[PUBMED:11430831]
[PUBMED:8302603]
[PUBMED:15218027]
[PUBMED:9140397]
[PUBMED:2423252]
[PUBMED:16113677]
[PUBMED:12147692]
[PUBMED:10648629]
[PUBMED:7854452]
[PUBMED:15070743]
[PUBMED:15301554]
[PUBMED:19881549]
[PUBMED:25992381]
[PUBMED:10871282]
[PUBMED:12726861]
Signaling by PDGF
[NCBI:1269478]
[REACTOME:R-HSA-186797]
[PUBMED:15207811]
[PUBMED:10508235]
[PUBMED:9739761]
Signaling by SCF-KIT
[NCBI:1269487]
[REACTOME:R-HSA-1433557]
[PUBMED:17350321]
[PUBMED:16483568]
[PUBMED:7688988]
[PUBMED:19540337]
[PUBMED:16475976]
[PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
[NCBI:1269617]
[REACTOME:R-HSA-2404192]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22044904]
[PUBMED:22649417]
Signaling by the B Cell Receptor (BCR)
[NCBI:1269183]
[REACTOME:R-HSA-983705]
[PUBMED:1702903]
[PUBMED:2011584]
[PUBMED:1081164]
[PUBMED:19065780]
[PUBMED:16849466]
[PUBMED:1375264]
[PUBMED:7538118]
[PUBMED:11901194]
[PUBMED:8580068]
[PUBMED:19249086]
[PUBMED:18596693]
[PUBMED:10648173]
[PUBMED:4589993]
[PUBMED:8163536]
[PUBMED:1376928]
[PUBMED:7688784]
[PUBMED:6335036]
[PUBMED:17052215]
[PUBMED:18818202]
[PUBMED:20206686]
[PUBMED:7592958]
[PUBMED:7524079]
[PUBMED:15489917]
[PUBMED:15509800]
[PUBMED:18187424]
[PUBMED:7927516]
[PUBMED:803528]
[PUBMED:19909372]
[PUBMED:20192804]
[PUBMED:8306975]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
[NCBI:137930]
[Pathway Interaction Database:met_pathway]
[PUBMED:10793146]
[PUBMED:8906793]
[PUBMED:11929826]
[PUBMED:10022866]
[PUBMED:11532961]
[PUBMED:12475979]
[PUBMED:1718989]
[PUBMED:1846706]
[PUBMED:10970810]
[PUBMED:10516287]
[PUBMED:12138161]
[PUBMED:11046147]
[PUBMED:18073207]
[PUBMED:12951049]
[PUBMED:15494312]
[PUBMED:9001234]
[PUBMED:11352916]
[PUBMED:11896055]
[PUBMED:9440692]
[PUBMED:8607979]
[PUBMED:12244132]
[PUBMED:11162460]
[PUBMED:11809798]
[PUBMED:9693375]
[PUBMED:14636584]
[PUBMED:17297451]
[PUBMED:17682062]
[PUBMED:19628037]
[PUBMED:11069926]
[PUBMED:18819921]
[PUBMED:16423831]
[PUBMED:10558875]
[PUBMED:16858414]
[PUBMED:10995442]
[PUBMED:20332103]
[PUBMED:11146548]
[PUBMED:18346875]
[PUBMED:17894413]
[PUBMED:9252406]
[PUBMED:17635922]
[PUBMED:11134526]
[PUBMED:2005882]
[PUBMED:19609305]
[PUBMED:8380735]
[PUBMED:16537482]
[PUBMED:10618718]
[PUBMED:9591773]
[PUBMED:12894582]
[PUBMED:9748249]
[PUBMED:11741535]
[PUBMED:17881575]
[PUBMED:10713050]
[PUBMED:1655790]
[PUBMED:11784715]
[PUBMED:10753869]
[PUBMED:10713700]
[PUBMED:11118451]
[PUBMED:16952352]
[PUBMED:15314156]
[PUBMED:19272169]
[PUBMED:12802068]
[PUBMED:17363898]
[PUBMED:7513258]
[PUBMED:1827664]
[PUBMED:2541345]
[PUBMED:8387483]
[PUBMED:16620780]
[PUBMED:11445578]
[PUBMED:10734310]
[PUBMED:16227611]
[PUBMED:12941962]
[PUBMED:15735664]
[PUBMED:19071214]
[PUBMED:7731718]
[PUBMED:19289496]
[PUBMED:11438654]
[PUBMED:11896612]
[PUBMED:11894096]
[PUBMED:11896575]
[PUBMED:7499247]
[PUBMED:12147692]
[PUBMED:11948414]
[PUBMED:19881549]
[PUBMED:19525225]
[PUBMED:14684163]
[PUBMED:17055484]
[PUBMED:9668053]
[PUBMED:10531383]
[PUBMED:9681449]
[PUBMED:1655405]
[PUBMED:12686592]
[PUBMED:19109251]
[PUBMED:10679787]
[PUBMED:9487126]
[PUBMED:9886295]
[PUBMED:12058075]
[PUBMED:15452053]
[PUBMED:9184210]
[PUBMED:10871282]
[PUBMED:17329361]
[PUBMED:2554238]
Signaling events mediated by Stem cell factor receptor (c-Kit)
[NCBI:138068]
[Pathway Interaction Database:kitpathway]
[PUBMED:12909618]
[PUBMED:10364466]
[PUBMED:10673502]
[PUBMED:15315962]
[PUBMED:12192036]
[PUBMED:12444928]
[PUBMED:15504549]
[PUBMED:8950973]
[PUBMED:11071635]
[PUBMED:12149208]
[PUBMED:11369651]
[PUBMED:9038210]
[PUBMED:10679268]
[PUBMED:15465815]
[PUBMED:10523831]
[PUBMED:8611693]
[PUBMED:15676208]
[PUBMED:11805142]
[PUBMED:10637471]
[PUBMED:9872323]
[PUBMED:11809791]
[PUBMED:11520784]
[PUBMED:12691919]
[PUBMED:10397721]
[PUBMED:15611091]
[PUBMED:12356726]
[PUBMED:9528781]
[PUBMED:1381360]
[PUBMED:9651683]
[PUBMED:10849422]
[PUBMED:9355737]
Signaling events mediated by VEGFR1 and VEGFR2
[NCBI:137940]
[Pathway Interaction Database:vegfr1_2_pathway]
[PUBMED:9398617]
[PUBMED:9405464]
[PUBMED:11494124]
[PUBMED:12963813]
[PUBMED:11756651]
[PUBMED:10744763]
[PUBMED:15060076]
[PUBMED:9600074]
[PUBMED:10376603]
[PUBMED:11425855]
[PUBMED:16337972]
[PUBMED:12154000]
[PUBMED:11978735]
[PUBMED:10692392]
[PUBMED:16763158]
[PUBMED:10361126]
[PUBMED:10748121]
[PUBMED:12598525]
[PUBMED:15026417]
[PUBMED:11948691]
[PUBMED:16966330]
[PUBMED:16835467]
[PUBMED:10409677]
[PUBMED:10908731]
[PUBMED:8903320]
[PUBMED:15962004]
[PUBMED:16633338]
[PUBMED:11387210]
[PUBMED:16839566]
[PUBMED:11312102]
[PUBMED:10207622]
[PUBMED:16787925]
[PUBMED:12171920]
[PUBMED:12509223]
[PUBMED:16760434]
[PUBMED:14724572]
[PUBMED:11704645]
[PUBMED:12821150]
[PUBMED:12881528]
[PUBMED:9790910]
[PUBMED:10376602]
[PUBMED:15247219]
[PUBMED:11333271]
[PUBMED:12214271]
[PUBMED:9804796]
[PUBMED:11986311]
[PUBMED:9182576]
[PUBMED:15217908]
[PUBMED:10749680]
[PUBMED:16763549]
Signaling events regulated by Ret tyrosine kinase
[NCBI:137915]
[Pathway Interaction Database:ret_pathway]
[PUBMED:11002419]
[PUBMED:17050626]
[PUBMED:11360177]
[PUBMED:7478523]
[PUBMED:12176011]
[PUBMED:12771945]
[PUBMED:14607833]
[PUBMED:7665556]
[PUBMED:8631863]
[PUBMED:11470823]
[PUBMED:15966897]
[PUBMED:12087092]
[PUBMED:16820412]
[PUBMED:15657578]
[PUBMED:10208419]
[PUBMED:9182757]
[PUBMED:8662982]
[PUBMED:9047383]
[PUBMED:12063395]
[PUBMED:15569713]
[PUBMED:15286081]
[PUBMED:10448070]
[PUBMED:16227613]
[PUBMED:11390647]
[PUBMED:15351743]
[PUBMED:8674117]
[PUBMED:11313948]
[PUBMED:2181380]
[PUBMED:9047384]
[PUBMED:8570170]
[PUBMED:11886862]
[PUBMED:9632781]
[PUBMED:16153436]
[PUBMED:11000521]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
Spry regulation of FGF signaling
[NCBI:1269398]
[REACTOME:R-HSA-1295596]
[PUBMED:9458049]
[PUBMED:16893902]
[PUBMED:19690147]
[PUBMED:19570949]
TCR signaling in naive CD4+ T cells
[NCBI:137998]
[Pathway Interaction Database:tcr_pathway]
[PUBMED:11376344]
[PUBMED:9094314]
[PUBMED:8083187]
[PUBMED:11994416]
[PUBMED:16365455]
[PUBMED:10072079]
[PUBMED:12361955]
[PUBMED:12755691]
[PUBMED:8642247]
[PUBMED:15125833]
[PUBMED:7509360]
[PUBMED:11353765]
[PUBMED:12941616]
[PUBMED:8700169]
[PUBMED:11120819]
[PUBMED:15899849]
[PUBMED:8990121]
[PUBMED:8702662]
[PUBMED:8164687]
[PUBMED:2141684]
[PUBMED:11567141]
[PUBMED:9846481]
[PUBMED:9489702]
[PUBMED:10811803]
[PUBMED:11368773]
[PUBMED:14557276]
[PUBMED:2548204]
[PUBMED:10318843]
[PUBMED:15536066]
[PUBMED:10652356]
[PUBMED:7568038]
[PUBMED:11175263]
[PUBMED:9438848]
[PUBMED:9692882]
[PUBMED:10209031]
[PUBMED:7509083]
[PUBMED:12874226]
[PUBMED:8673706]
[PUBMED:16733527]
[PUBMED:9822663]
[PUBMED:12738795]
[PUBMED:11904433]
[PUBMED:8084588]
[PUBMED:8114715]
[PUBMED:9312162]
[PUBMED:8790380]
[PUBMED:9677202]
[PUBMED:15802604]
[PUBMED:14702343]
[PUBMED:10903746]
[PUBMED:10807788]
[PUBMED:8176201]
[PUBMED:9207119]
[PUBMED:10790433]
[PUBMED:8892604]
[PUBMED:9665884]
[PUBMED:1639064]
[PUBMED:12421919]
[PUBMED:8246987]
[PUBMED:9710204]
[PUBMED:8146197]
[PUBMED:2190221]
[PUBMED:10229072]
[PUBMED:10021361]
[PUBMED:9924026]
[PUBMED:12186560]
[PUBMED:16649996]
[PUBMED:11287959]
[PUBMED:12917261]
[PUBMED:7545666]
[PUBMED:11250890]
[PUBMED:12842872]
[PUBMED:15879121]
[PUBMED:11567140]
[PUBMED:10209041]
[PUBMED:10556826]
[PUBMED:8183372]
[PUBMED:12397360]
[PUBMED:10506192]
[PUBMED:10861059]
[PUBMED:12507424]
[PUBMED:12845325]
[PUBMED:10745081]
[PUBMED:8195151]
[PUBMED:12024036]
[PUBMED:7524075]
[PUBMED:1464315]
[PUBMED:12138205]
[PUBMED:7544353]
[PUBMED:16906149]
[PUBMED:9637919]
[PUBMED:2470098]
[PUBMED:3919143]
[PUBMED:16005298]
[PUBMED:10918068]
[PUBMED:8636141]
[PUBMED:16921383]
[PUBMED:8479536]
[PUBMED:7556092]
[PUBMED:16582901]
[PUBMED:8805223]
[PUBMED:15933714]
[PUBMED:10224278]
[PUBMED:9819387]
[PUBMED:12881521]
[PUBMED:14988727]
[PUBMED:16849481]
[PUBMED:11390650]
TRIF-mediated TLR3/TLR4 signaling
[NCBI:1269221]
[REACTOME:R-HSA-937061]
[PUBMED:15814722]
[PUBMED:12855817]
[PUBMED:14739303]
Tie2 Signaling
[NCBI:1269374]
[REACTOME:R-HSA-210993]
[PUBMED:11566266]
[PUBMED:11969368]
[PUBMED:9764820]
[PUBMED:11191051]
Toll Like Receptor 3 (TLR3) Cascade
[NCBI:1269219]
[REACTOME:R-HSA-168164]
[PUBMED:19627256]
[PUBMED:15733829]
[PUBMED:18202435]
Toll Like Receptor 4 (TLR4) Cascade
[NCBI:1269234]
[REACTOME:R-HSA-166016]
Toll-Like Receptors Cascades
[NCBI:1269204]
[REACTOME:R-HSA-168898]
[PUBMED:15950447]
[PUBMED:12893815]
[PUBMED:15976490]
[PUBMED:15585605]
[PUBMED:14751757]
VEGFR1 specific signals
[NCBI:137924]
[Pathway Interaction Database:vegfr1_pathway]
[PUBMED:9299537]
[PUBMED:9751730]
[PUBMED:9722576]
[PUBMED:14633857]
[PUBMED:11978735]
[PUBMED:11278319]
[PUBMED:12649282]
[PUBMED:16839566]
[PUBMED:12598525]
[PUBMED:12171920]
[PUBMED:12796773]
[PUBMED:16633338]
[PUBMED:11312102]
[PUBMED:9295307]
[PUBMED:10908731]
[PUBMED:16787925]
[PUBMED:11704645]
[PUBMED:9790910]
[PUBMED:10376602]
[PUBMED:9804796]
[PUBMED:11986311]
[PUBMED:10749680]
[PUBMED:12214271]
[PUBMED:9398617]
[PUBMED:8621427]
[PUBMED:11425855]
[PUBMED:15001553]
[PUBMED:10376603]
[PUBMED:7824266]
[PUBMED:10842181]
[PUBMED:9600074]