full name
nitric oxide synthase 1

synonyms
bNOS, IHPS1, N-NOS, NC-NOS, nNOS, NOS, NOS1, ENSG00000089250

HGNC
HGNC:7872

Entrez Gene
Gene:4842

ENSEMBL
ENSG00000089250

location
chr: 12
start: 117645921
stop: 117799607
strand: -

transcripts
NM_000620.4
NM_001204218.1
NM_001204214.1
NM_001204213.1

pathways
Alzheimer's disease [NCBI:83097] [KEGG:hsa05010] [PUBMED:18782350] [PUBMED:18035450] [PUBMED:15177383] [PUBMED:10527810] [PUBMED:15363492] [PUBMED:16677790] [PUBMED:15295589] [PUBMED:17055782] [PUBMED:15864339] [PUBMED:15750290] [PUBMED:18675468] [PUBMED:15232608] [PUBMED:9848086] [PUBMED:11484003] [PUBMED:10830966] [PUBMED:16529745] [PUBMED:17568632]
Amyotrophic lateral sclerosis (ALS) [NCBI:83099] [KEGG:hsa05014] [PUBMED:16026864] [PUBMED:16924260] [PUBMED:11513882] [PUBMED:17015226] [PUBMED:16723044] [PUBMED:10970056] [PUBMED:16909020] [PUBMED:12531867] [PUBMED:16713195] [PUBMED:16603792] [PUBMED:11870681] [PUBMED:16050975] [PUBMED:17409386] [PUBMED:11239414] [PUBMED:18519638] [PUBMED:14569202] [PUBMED:12728264] [PUBMED:11715057] [PUBMED:17566607] [PUBMED:17434459] [PUBMED:16909017] [PUBMED:12595144] [PUBMED:15310460] [PUBMED:14739060]
Apelin signaling pathway [NCBI:1492886] [KEGG:hsa04371] [PUBMED:23973488] [PUBMED:16182514] [PUBMED:21725702] [PUBMED:22842084] [PUBMED:27825851] [PUBMED:27650065] [PUBMED:22140623] [PUBMED:23943882] [PUBMED:26944568] [PUBMED:24055369] [PUBMED:26385179] [PUBMED:26143239] [PUBMED:22028387] [PUBMED:26254105] [PUBMED:26756969] [PUBMED:22995518] [PUBMED:27979574] [PUBMED:23924696] [PUBMED:21464822] [PUBMED:25914650] [PUBMED:24990699] [PUBMED:26607438] [PUBMED:25164121] [PUBMED:25275559] [PUBMED:25139773] [PUBMED:25931124] [PUBMED:19093215] [PUBMED:20539939] [PUBMED:25652330] [PUBMED:18272138] [PUBMED:23603510]
Arginine and proline metabolism [NCBI:82957] [KEGG:hsa00330] [PUBMED:15590624] [PUBMED:5288244] [PUBMED:16499623]
Arginine biosynthesis [NCBI:82943] [KEGG:hsa00220]
Calcium signaling pathway [NCBI:83050] [KEGG:hsa04020] [PUBMED:11080247] [PUBMED:14572802] [PUBMED:11413485] [PUBMED:22129055] [PUBMED:10508738] [PUBMED:15000521] [PUBMED:9235901] [PUBMED:7861177] [PUBMED:9149541] [PUBMED:14517314] [PUBMED:15111104] [PUBMED:11698232] [PUBMED:10331643] [PUBMED:12838335] [PUBMED:8125957] [PUBMED:19172794] [PUBMED:10997573] [PUBMED:21338471] [PUBMED:11299192] [PUBMED:22002090] [PUBMED:12972622]
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:19808464] [PUBMED:26140724] [PUBMED:21357845]
Circadian entrainment [NCBI:698773] [KEGG:hsa04713] [PUBMED:15016477] [PUBMED:12700026] [PUBMED:20605968] [PUBMED:15813931] [PUBMED:15930378] [PUBMED:12573527] [PUBMED:17586087] [PUBMED:20664079] [PUBMED:17646042] [PUBMED:17167088] [PUBMED:16217123] [PUBMED:11294753] [PUBMED:19109992] [PUBMED:10446325] [PUBMED:10208575] [PUBMED:11086993] [PUBMED:19449447]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Ion homeostasis [NCBI:1339121] [REACTOME:R-HSA-5578775] [PUBMED:26140724] [PUBMED:17017901]
Long-term depression [NCBI:83086] [KEGG:hsa04730] [PUBMED:9602501] [PUBMED:9735948] [PUBMED:14509570] [PUBMED:11427694] [PUBMED:12415297]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Nitric oxide stimulates guanylate cyclase [NCBI:1269343] [REACTOME:R-HSA-392154] [PUBMED:12881475]
Phagosome [NCBI:153910] [KEGG:hsa04145] [PUBMED:17637737] [PUBMED:18513324] [PUBMED:15894272] [PUBMED:10684585] [PUBMED:18492791] [PUBMED:15036145] [PUBMED:17245426]
Platelet homeostasis [NCBI:1269341] [REACTOME:R-HSA-418346] [PUBMED:10798271]
ROS, RNS production in phagocytes [NCBI:1269138] [REACTOME:R-HSA-1222556] [PUBMED:23617726] [PUBMED:19369951]
Salivary secretion [NCBI:153376] [KEGG:hsa04970] [PUBMED:8105741] [PUBMED:10682899] [PUBMED:10928320] [PUBMED:15709965] [PUBMED:17347411] [PUBMED:9720759] [PUBMED:16712780] [PUBMED:16799262] [PUBMED:17157080] [PUBMED:18626068] [PUBMED:15153696] [PUBMED:11936453] [PUBMED:20224180]
citrulline-nitric oxide cycle [NCBI:703092] [BIOCYC:HUMAN_PWY-4983] [PUBMED:7511585] [PUBMED:2236071] [PUBMED:1731766]