full name
purinergic receptor P2X 7

synonyms
P2X7, P2RX7, ENSG00000089041

HGNC
HGNC:8537

Entrez Gene
Gene:5027

ENSEMBL
ENSG00000089041

location
chr: 12
start: 121570622
stop: 121624439
strand: +

transcripts
NR_033953.1
NR_033948.1
NR_033949.1
NR_033950.1
NR_033951.1
ENST00000546057.1
NR_033955.1
NR_033954.1
NR_033952.1
NR_033956.1

pathways
Calcium signaling pathway [NCBI:83050] [KEGG:hsa04020] [PUBMED:11080247] [PUBMED:14572802] [PUBMED:11413485] [PUBMED:22129055] [PUBMED:10508738] [PUBMED:15000521] [PUBMED:9235901] [PUBMED:7861177] [PUBMED:9149541] [PUBMED:14517314] [PUBMED:15111104] [PUBMED:11698232] [PUBMED:10331643] [PUBMED:12838335] [PUBMED:8125957] [PUBMED:19172794] [PUBMED:10997573] [PUBMED:21338471] [PUBMED:11299192] [PUBMED:22002090] [PUBMED:12972622]
Elevation of cytosolic Ca2+ levels [NCBI:1269346] [REACTOME:R-HSA-139853] [PUBMED:17703229] [PUBMED:19422456] [PUBMED:18308196]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Inflammasomes [NCBI:1269253] [REACTOME:R-HSA-622312] [PUBMED:20303873] [PUBMED:19120479]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
NOD-like receptor signaling pathway [NCBI:122191] [KEGG:hsa04621] [PUBMED:25330206] [PUBMED:21575908] [PUBMED:23846113] [PUBMED:26549800] [PUBMED:16493424] [PUBMED:23124073] [PUBMED:24840700] [PUBMED:27291964] [PUBMED:27012466] [PUBMED:24707857] [PUBMED:19767725] [PUBMED:25879280] [PUBMED:23215645] [PUBMED:22819539] [PUBMED:23702978] [PUBMED:20643110] [PUBMED:25879288] [PUBMED:26655628] [PUBMED:25145756] [PUBMED:24718315] [PUBMED:26482951] [PUBMED:25526305] [PUBMED:26121197] [PUBMED:22430786]
Neuroactive ligand-receptor interaction [NCBI:83053] [KEGG:hsa04080]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways [NCBI:1269251] [REACTOME:R-HSA-168643] [PUBMED:18928408]
Platelet calcium homeostasis [NCBI:1269345] [REACTOME:R-HSA-418360] [PUBMED:18308196] [PUBMED:19422456]
Platelet homeostasis [NCBI:1269341] [REACTOME:R-HSA-418346] [PUBMED:10798271]
The NLRP3 inflammasome [NCBI:1269254] [REACTOME:R-HSA-844456] [PUBMED:19501527] [PUBMED:20303873]