full name
nuclear receptor corepressor 2
synonyms
CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1, NCOR2, ENSG00000196498
HGNC
HGNC:7673
Entrez Gene
Gene:9612
ENSEMBL
ENSG00000196498
location
chr: 12
start: 124808957
stop: 125052079
strand: -
transcripts
NM_001077261.3
NM_001206654.1
NM_006312.5
pathways
Chromatin modifying enzymes
[NCBI:1270434]
[REACTOME:R-HSA-3247509]
Chromatin organization
[NCBI:1270433]
[REACTOME:R-HSA-4839726]
[PUBMED:21342762]
[PUBMED:15598472]
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
[NCBI:1268891]
[REACTOME:R-HSA-2894862]
[PUBMED:15472075]
[PUBMED:17646408]
[PUBMED:17646409]
[PUBMED:16738328]
Constitutive Signaling by NOTCH1 PEST Domain Mutants
[NCBI:1268889]
[REACTOME:R-HSA-2644606]
[PUBMED:15472075]
[PUBMED:17646408]
[PUBMED:17646409]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
Downregulation of SMAD2/3:SMAD4 transcriptional activity
[NCBI:1269529]
[REACTOME:R-HSA-2173795]
[PUBMED:19917253]
[PUBMED:11389444]
[PUBMED:10535941]
[PUBMED:10199400]
[PUBMED:16751101]
[PUBMED:17591695]
[PUBMED:10485843]
[PUBMED:21095583]
[PUBMED:11427533]
[PUBMED:19135894]
[PUBMED:10531062]
[PUBMED:22045334]
[PUBMED:10549282]
Epstein-Barr virus infection
[NCBI:585562]
[KEGG:hsa05169]
[PUBMED:1658397]
[PUBMED:10683340]
[PUBMED:19375142]
[PUBMED:12438576]
[PUBMED:12910248]
[PUBMED:10400785]
[PUBMED:16007144]
[PUBMED:14576817]
[PUBMED:18559925]
[PUBMED:16352731]
[PUBMED:7895172]
[PUBMED:15510157]
[PUBMED:21518914]
[PUBMED:10891508]
[PUBMED:14673102]
[PUBMED:17159145]
[PUBMED:15542638]
[PUBMED:18786993]
[PUBMED:16603506]
[PUBMED:10644367]
[PUBMED:15021898]
[PUBMED:10666279]
[PUBMED:9565632]
Fatty acid, triacylglycerol, and ketone body metabolism
[NCBI:1270010]
[REACTOME:R-HSA-535734]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
HDACs deacetylate histones
[NCBI:1270436]
[REACTOME:R-HSA-3214815]
[PUBMED:21872466]
[PUBMED:12429021]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins
[NCBI:1270001]
[REACTOME:R-HSA-556833]
NOTCH1 Intracellular Domain Regulates Transcription
[NCBI:1269537]
[REACTOME:R-HSA-2122947]
[PUBMED:11044625]
[PUBMED:8649374]
[PUBMED:21737748]
[PUBMED:9694793]
[PUBMED:20972443]
[PUBMED:11585921]
[PUBMED:17114293]
[PUBMED:8001118]
[PUBMED:18094723]
[PUBMED:8687460]
[PUBMED:16256737]
[PUBMED:16530044]
[PUBMED:12050117]
[PUBMED:10964718]
[PUBMED:12391150]
[PUBMED:7566092]
[PUBMED:15546612]
[PUBMED:15107403]
[PUBMED:18374649]
[PUBMED:14980219]
[PUBMED:11461910]
[PUBMED:10713164]
Notch signaling pathway
[NCBI:83062]
[KEGG:hsa04330]
[NCBI:169345]
[Pathway Interaction Database:notch_pathway]
[PUBMED:11459941]
[PUBMED:12682059]
[PUBMED:11825871]
[PUBMED:17658278]
[PUBMED:15998794]
[PUBMED:11101851]
[PUBMED:19686683]
[PUBMED:18490439]
[PUBMED:11150244]
[PUBMED:9694793]
[PUBMED:10206645]
[PUBMED:19704010]
[PUBMED:16137758]
[PUBMED:15288258]
[PUBMED:17392792]
[PUBMED:8749394]
[PUBMED:15965470]
[PUBMED:14566063]
[PUBMED:19567869]
[PUBMED:11585921]
[PUBMED:18676613]
[PUBMED:12913000]
[PUBMED:10593990]
[PUBMED:15274632]
[PUBMED:11777909]
[PUBMED:12015972]
[PUBMED:10028969]
[PUBMED:18043734]
[PUBMED:17658279]
[PUBMED:17575125]
[PUBMED:10958687]
[PUBMED:15300010]
[PUBMED:10882062]
[PUBMED:12374742]
[PUBMED:11782429]
[PUBMED:9653148]
[PUBMED:9315665]
[PUBMED:8643690]
[PUBMED:17114293]
[PUBMED:10837024]
[PUBMED:15067010]
[PUBMED:17296795]
[PUBMED:10940313]
[PUBMED:18628966]
[PUBMED:12826675]
[PUBMED:12681948]
[PUBMED:16492672]
[PUBMED:12551931]
[PUBMED:15082708]
[PUBMED:12464310]
[PUBMED:12794186]
[PUBMED:16107360]
[PUBMED:19726682]
[PUBMED:11486031]
[PUBMED:16287852]
[PUBMED:12297508]
[PUBMED:16061358]
[PUBMED:17107962]
[PUBMED:9244302]
[PUBMED:11425854]
[PUBMED:9620803]
[PUBMED:15272268]
[PUBMED:18417156]
[PUBMED:16000382]
[PUBMED:11896183]
[PUBMED:11604511]
[PUBMED:16847353]
[PUBMED:11432830]
[PUBMED:15652348]
[PUBMED:12417415]
[PUBMED:14567914]
[PUBMED:11006133]
[PUBMED:18077452]
[PUBMED:16144902]
[PUBMED:15288257]
[PUBMED:15585829]
[PUBMED:12370315]
[PUBMED:15288260]
[PUBMED:17434929]
[PUBMED:12814948]
[PUBMED:10882063]
[PUBMED:11518718]
Notch-mediated HES/HEY network
[NCBI:169347]
[Pathway Interaction Database:hes_heypathway]
[PUBMED:15546612]
[PUBMED:11038350]
[PUBMED:12065598]
[PUBMED:11741889]
[PUBMED:10851137]
[PUBMED:10205173]
[PUBMED:10747963]
[PUBMED:10913198]
[PUBMED:11101851]
[PUBMED:16201968]
[PUBMED:12488457]
[PUBMED:12370315]
[PUBMED:19116245]
[PUBMED:16025100]
[PUBMED:11486044]
[PUBMED:15607978]
[PUBMED:15467735]
[PUBMED:14739937]
[PUBMED:9694793]
[PUBMED:8749394]
[PUBMED:16782059]
[PUBMED:12972610]
[PUBMED:17392792]
[PUBMED:11334435]
[PUBMED:11486045]
[PUBMED:16753023]
[PUBMED:15485867]
[PUBMED:15866158]
[PUBMED:16199874]
[PUBMED:12374742]
[PUBMED:9570950]
[PUBMED:10964718]
[PUBMED:16682003]
[PUBMED:16287852]
[PUBMED:10692439]
[PUBMED:11095750]
[PUBMED:11287612]
[PUBMED:15314183]
[PUBMED:15156153]
[PUBMED:15684393]
[PUBMED:7566092]
[PUBMED:11604511]
[PUBMED:9819403]
[PUBMED:15563463]
[PUBMED:15870295]
RXR and RAR heterodimerization with other nuclear receptor
[NCBI:137975]
[Pathway Interaction Database:rxr_vdr_pathway]
[PUBMED:8394351]
[PUBMED:15284334]
[PUBMED:9223286]
[PUBMED:8389594]
[PUBMED:15650024]
[PUBMED:7744246]
[PUBMED:11741944]
[PUBMED:12359143]
[PUBMED:8060315]
[PUBMED:16611854]
[PUBMED:15731112]
[PUBMED:15509776]
[PUBMED:16181625]
[PUBMED:17595322]
[PUBMED:7705655]
[PUBMED:8621574]
[PUBMED:7760852]
[PUBMED:11287605]
[PUBMED:15187081]
[PUBMED:8164684]
[PUBMED:8381967]
[PUBMED:10858438]
[PUBMED:7958963]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
[NCBI:1270029]
[REACTOME:R-HSA-400206]
[PUBMED:18288277]
[PUBMED:10529898]
[PUBMED:16476485]
[PUBMED:16503871]
Retinoic acid receptors-mediated signaling
[NCBI:138039]
[Pathway Interaction Database:retinoic_acid_pathway]
[PUBMED:9192892]
[PUBMED:16417524]
[PUBMED:7476969]
[PUBMED:12032153]
[PUBMED:8145770]
[PUBMED:12824162]
[PUBMED:10938135]
[PUBMED:9351827]
[PUBMED:15608670]
[PUBMED:8855229]
[PUBMED:16456540]
[PUBMED:16613989]
[PUBMED:15688020]
[PUBMED:16275922]
[PUBMED:15657432]
[PUBMED:11467847]
[PUBMED:16038797]
[PUBMED:12885766]
[PUBMED:14535629]
[PUBMED:10608897]
[PUBMED:12110588]
[PUBMED:9230306]
[PUBMED:16093479]
[PUBMED:16723356]
[PUBMED:11955452]
[PUBMED:16769902]
[PUBMED:10748061]
[PUBMED:8164684]
[PUBMED:17088940]
[PUBMED:10938283]
[PUBMED:7791761]
[PUBMED:12032135]
[PUBMED:11006275]
[PUBMED:10383391]
[PUBMED:11606411]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by NOTCH
[NCBI:1269530]
[REACTOME:R-HSA-157118]
Signaling by NOTCH1
[NCBI:1269535]
[REACTOME:R-HSA-1980143]
[PUBMED:20972443]
[PUBMED:8649374]
[PUBMED:11740940]
[PUBMED:15965470]
[PUBMED:16284625]
[PUBMED:9694793]
[PUBMED:19567869]
[PUBMED:12354787]
[PUBMED:11585921]
[PUBMED:20418862]
[PUBMED:11226752]
[PUBMED:9590294]
[PUBMED:9315665]
[PUBMED:17114293]
[PUBMED:18094723]
[PUBMED:10964718]
[PUBMED:10879540]
[PUBMED:8001118]
[PUBMED:12050117]
[PUBMED:18043734]
[PUBMED:9819428]
[PUBMED:15824097]
[PUBMED:9244301]
[PUBMED:16256737]
[PUBMED:8687460]
[PUBMED:19726682]
[PUBMED:8313469]
[PUBMED:15574878]
[PUBMED:18296446]
[PUBMED:16530044]
[PUBMED:9620803]
[PUBMED:18237417]
[PUBMED:7566092]
[PUBMED:18628966]
[PUBMED:12391150]
[PUBMED:12530964]
[PUBMED:11006133]
[PUBMED:18374649]
[PUBMED:15107403]
[PUBMED:18077452]
[PUBMED:15652348]
[PUBMED:15546612]
[PUBMED:10882063]
[PUBMED:14980219]
[PUBMED:10713164]
[PUBMED:9462510]
[PUBMED:11461910]
[PUBMED:14567914]
[PUBMED:17003037]
[PUBMED:17028573]
[PUBMED:11044625]
[PUBMED:10206645]
[PUBMED:19524514]
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
[NCBI:1268890]
[REACTOME:R-HSA-2894858]
[PUBMED:15472075]
Signaling by NOTCH1 PEST Domain Mutants in Cancer
[NCBI:1268888]
[REACTOME:R-HSA-2644602]
[PUBMED:17646408]
[PUBMED:15472075]
[PUBMED:17646409]
Signaling by NOTCH1 in Cancer
[NCBI:1268883]
[REACTOME:R-HSA-2644603]
[PUBMED:17646409]
[PUBMED:10367900]
[PUBMED:16738328]
[PUBMED:15951812]
[PUBMED:22399357]
[PUBMED:15546612]
[PUBMED:11461910]
[PUBMED:9118226]
[PUBMED:15951813]
[PUBMED:17646408]
[PUBMED:15472075]
[PUBMED:11585921]
[PUBMED:17909001]
[PUBMED:16612405]
[PUBMED:1831692]
[PUBMED:15187027]
Signaling by TGF-beta Receptor Complex
[NCBI:1269523]
[REACTOME:R-HSA-170834]
[PUBMED:19648010]
Signaling events mediated by HDAC Class I
[NCBI:137997]
[Pathway Interaction Database:hdac_classi_pathway]
[PUBMED:9885572]
[PUBMED:14701748]
[PUBMED:10888618]
[PUBMED:12393750]
[PUBMED:9804427]
[PUBMED:9139820]
[PUBMED:12408818]
[PUBMED:16809764]
[PUBMED:12788099]
[PUBMED:11533489]
[PUBMED:15831498]
[PUBMED:15701600]
[PUBMED:11532945]
[PUBMED:12183469]
[PUBMED:16428440]
[PUBMED:9150134]
[PUBMED:12972430]
[PUBMED:11486036]
[PUBMED:15920470]
[PUBMED:9150135]
[PUBMED:9651585]
[PUBMED:11960997]
[PUBMED:9326634]
[PUBMED:11278251]
[PUBMED:14521922]
[PUBMED:9197243]
[PUBMED:9346952]
[PUBMED:16371367]
[PUBMED:10444591]
[PUBMED:15653507]
[PUBMED:15920471]
[PUBMED:11919195]
Signaling events mediated by HDAC Class II
[NCBI:138062]
[Pathway Interaction Database:hdac_classii_pathway]
[PUBMED:15916966]
[PUBMED:10869435]
[PUBMED:10898795]
[PUBMED:16051668]
[PUBMED:12032081]
[PUBMED:12606581]
[PUBMED:11804585]
[PUBMED:11466315]
[PUBMED:11567998]
[PUBMED:16767219]
[PUBMED:12024216]
[PUBMED:16166628]
[PUBMED:16221676]
[PUBMED:11948178]
[PUBMED:10220385]
[PUBMED:12663674]
[PUBMED:14668799]
[PUBMED:16236793]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
[NCBI:1269527]
[REACTOME:R-HSA-2173793]
[PUBMED:12150994]
[PUBMED:16751101]
[PUBMED:10199400]
[PUBMED:18568018]
[PUBMED:19135894]
[PUBMED:10531062]
Transcriptional regulation of white adipocyte differentiation
[NCBI:1270345]
[REACTOME:R-HSA-381340]
[PUBMED:21082419]
[PUBMED:17956727]
[PUBMED:17475546]
[PUBMED:1840554]
[PUBMED:17139329]
[PUBMED:15860371]
[PUBMED:18518822]
[PUBMED:10603305]
[PUBMED:7531665]
[PUBMED:20054179]
[PUBMED:7838715]
[PUBMED:16054042]
[PUBMED:17060461]
[PUBMED:17011499]
[PUBMED:16380219]
[PUBMED:8970730]
