full name
pancreatic and duodenal homeobox 1
synonyms
GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1, PDX1, ENSG00000139515
HGNC
HGNC:6107
Entrez Gene
Gene:3651
ENSEMBL
ENSG00000139515
location
chr: 13
start: 28494168
stop: 28500451
strand: +
OMIM
OMIM:600733:
PDX1
(Autosomal dominant inheritance)
OMIM:606392:
MODY, type IV
OMIM:260370:
Pancreatic agenesis 1
OMIM:125853:
{Diabetes mellitus, type II, susceptibility to}
transcripts
NM_000209.3
pathways
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
FOXA2 and FOXA3 transcription factor networks
[NCBI:137911]
[Pathway Interaction Database:hnf3bpathway]
[PUBMED:14500912]
[PUBMED:9632808]
[PUBMED:8668179]
[PUBMED:2786140]
[PUBMED:10748140]
[PUBMED:8662915]
[PUBMED:12865419]
[PUBMED:12145169]
[PUBMED:15314688]
[PUBMED:12911579]
[PUBMED:15123725]
[PUBMED:16098831]
[PUBMED:10455192]
[PUBMED:15616563]
[PUBMED:7524494]
[PUBMED:7565696]
[PUBMED:15959514]
[PUBMED:11278466]
[PUBMED:9369482]
[PUBMED:8813720]
Insulin secretion
[NCBI:777534]
[KEGG:hsa04911]
[PUBMED:9715374]
[PUBMED:10605628]
[PUBMED:9914469]
[PUBMED:17306374]
[PUBMED:20055708]
[PUBMED:15655710]
[PUBMED:19817784]
[PUBMED:19074620]
[PUBMED:14693691]
[PUBMED:17084085]
[PUBMED:20551594]
[PUBMED:19036624]
[PUBMED:22970724]
[PUBMED:20225132]
[PUBMED:19817800]
[PUBMED:22974438]
[PUBMED:21934040]
[PUBMED:15271645]
[PUBMED:19660440]
[PUBMED:11522660]
Maturity onset diabetes of the young
[NCBI:83096]
[KEGG:hsa04950]
[PUBMED:14614204]
[PUBMED:15604203]
[PUBMED:15028942]
[PUBMED:15298336]
Regulation of beta-cell development
[NCBI:1270337]
[REACTOME:R-HSA-186712]
[PUBMED:15298336]
[PUBMED:18094957]
[PUBMED:11575290]
[PUBMED:12591178]
Regulation of gene expression in beta cells
[NCBI:1270341]
[REACTOME:R-HSA-210745]
[PUBMED:12591178]
[PUBMED:15298336]
Regulation of gene expression in early pancreatic precursor cells
[NCBI:1270338]
[REACTOME:R-HSA-210747]
[PUBMED:12591178]
[PUBMED:15298336]
Type II diabetes mellitus
[NCBI:83094]
[KEGG:hsa04930]
[PUBMED:12480546]
[PUBMED:15759102]
[PUBMED:9011569]
[PUBMED:11078440]
[PUBMED:11390407]
[PUBMED:15258147]
[PUBMED:15823385]
[PUBMED:11272200]
[PUBMED:11325516]
[PUBMED:15733744]
[PUBMED:9974390]
[PUBMED:7491105]
[PUBMED:15585596]
