full name
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease

synonyms
bA555G22.1, dis3p, EXOSC11, KIAA1008, RP11-342J4.3, RRP44, DIS3, ENSG00000083520

HGNC
HGNC:20604

Entrez Gene
Gene:22894

ENSEMBL
ENSG00000083520

location
chr: 13
start: 73329540
stop: 73356344
strand: -

transcripts
NM_014953.3
NM_001128226.1

pathways
ATF4 activates genes [NCBI:1268762] [REACTOME:R-HSA-380994] [PUBMED:18840095] [PUBMED:16931790] [PUBMED:14742429] [PUBMED:16687408] [PUBMED:20022965] [PUBMED:18426796] [PUBMED:14630918] [PUBMED:16912112]
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA [NCBI:1269727] [REACTOME:R-HSA-450385] [PUBMED:12440953] [PUBMED:12704645] [PUBMED:11719186] [PUBMED:15687258] [PUBMED:16391004]
Deadenylation-dependent mRNA decay [NCBI:1269712] [REACTOME:R-HSA-429914] [PUBMED:19239894] [PUBMED:14749774] [PUBMED:17245413] [PUBMED:15475613] [PUBMED:16141059] [PUBMED:11283721]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
KSRP (KHSRP) binds and destabilizes mRNA [NCBI:1269729] [REACTOME:R-HSA-450604] [PUBMED:16391004] [PUBMED:12704645] [PUBMED:12440953]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
PERK regulates gene expression [NCBI:1268761] [REACTOME:R-HSA-381042] [PUBMED:18048764] [PUBMED:17956313] [PUBMED:18038217] [PUBMED:18436705]
RNA degradation [NCBI:117291] [KEGG:hsa03018] [PUBMED:16939780] [PUBMED:17560162] [PUBMED:17471261] [PUBMED:16968219] [PUBMED:16766188] [PUBMED:17447862] [PUBMED:19239894]
Regulation of mRNA stability by proteins that bind AU-rich elements [NCBI:1269725] [REACTOME:R-HSA-450531] [PUBMED:12440953] [PUBMED:12704645] [PUBMED:15460540] [PUBMED:16391004]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA [NCBI:1269728] [REACTOME:R-HSA-450513] [PUBMED:18481987] [PUBMED:16391004] [PUBMED:12440953] [PUBMED:12704645]
Unfolded Protein Response (UPR) [NCBI:1268756] [REACTOME:R-HSA-381119] [PUBMED:18436705] [PUBMED:18038217] [PUBMED:27067637] [PUBMED:16365312] [PUBMED:18048764] [PUBMED:15952902]
mRNA decay by 3' to 5' exoribonuclease [NCBI:1269714] [REACTOME:R-HSA-429958] [PUBMED:14749774] [PUBMED:19239894] [PUBMED:15475613] [PUBMED:16141059] [PUBMED:17245413] [PUBMED:11283721]