full name
protoporphyrinogen oxidase

synonyms
PPO, V290M, VP, PPOX, ENSG00000143224

HGNC
HGNC:9280

Entrez Gene
Gene:5498

ENSEMBL
ENSG00000143224

location
chr: 1
start: 161135832
stop: 161148136
strand: +

OMIM
OMIM:600923: PPOX (Autosomal dominant inheritance)
OMIM:176200: Porphyria variegata

transcripts
NM_001122764.1
NM_000309.3

pathways
Heme biosynthesis [NCBI:1270187] [REACTOME:R-HSA-189451] [PUBMED:16839620] [PUBMED:10522552]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of porphyrins [NCBI:1270186] [REACTOME:R-HSA-189445]
Porphyrin and chlorophyll metabolism [NCBI:83021] [KEGG:hsa00860] [PUBMED:12195810] [PUBMED:11283349] [PUBMED:10217486] [PUBMED:11007789] [PUBMED:10518530] [PUBMED:12055304] [PUBMED:12196148] [PUBMED:17506685] [PUBMED:16245042] [PUBMED:23922391] [PUBMED:23042036] [PUBMED:9461500]
heme biosynthesis [NCBI:545289] [BIOCYC:HUMAN_PWY-5920] [PUBMED:6769048] [PUBMED:7592564] [PUBMED:3816774] [PUBMED:20506125] [PUBMED:23471474] [PUBMED:9564029] [PUBMED:7592562] [PUBMED:3346226]
heme biosynthesis from uroporphyrinogen-III I [NCBI:142222] [BIOCYC:HUMAN_HEME-BIOSYNTHESIS-II] [PUBMED:20823222]