full name
transcription factor Dp-1

synonyms
Dp-1, DP1, DRTF1, TFDP1, ENSG00000198176

HGNC
HGNC:11749

Entrez Gene
Gene:7027

ENSEMBL
ENSG00000198176

location
chr: 13
start: 114239003
stop: 114295788
strand: +

transcripts
NR_026580.1
NM_007111.4

pathways
Activation of BH3-only proteins [NCBI:1270270] [REACTOME:R-HSA-114452] [PUBMED:12209154] [PUBMED:14634621]
Activation of NOXA and translocation to mitochondria [NCBI:1270272] [REACTOME:R-HSA-111448] [PUBMED:14684737] [PUBMED:15126337]
Activation of PUMA and translocation to mitochondria [NCBI:1270273] [REACTOME:R-HSA-139915] [PUBMED:14684737] [PUBMED:11463392]
Apoptosis [NCBI:83060] [KEGG:hsa04210] [NCBI:1270262] [REACTOME:R-HSA-109581] [PUBMED:12189384] [PUBMED:20533903] [PUBMED:18208375] [PUBMED:22429822] [PUBMED:15218528] [PUBMED:24769728] [PUBMED:18023214] [PUBMED:25526085] [PUBMED:23070002] [PUBMED:15654015] [PUBMED:15601572] [PUBMED:14561771] [PUBMED:24278747] [PUBMED:21914490] [PUBMED:22465226] [PUBMED:21145844] [PUBMED:12838338] [PUBMED:18238895] [PUBMED:12949498] [PUBMED:18304445] [PUBMED:14737178] [PUBMED:26231733] [PUBMED:9916983] [PUBMED:14634621] [PUBMED:19770840] [PUBMED:22075987] [PUBMED:4561027] [PUBMED:20075940] [PUBMED:9894605] [PUBMED:26615431] [PUBMED:12505355] [PUBMED:11520933] [PUBMED:19148180] [PUBMED:16397578] [PUBMED:15719025] [PUBMED:15322527] [PUBMED:15725726] [PUBMED:12209154] [PUBMED:23803157]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cell cycle [NCBI:83054] [KEGG:hsa04110] [PUBMED:7973727] [PUBMED:17568790] [PUBMED:9832503] [PUBMED:16936746] [PUBMED:9029154] [PUBMED:12573239] [PUBMED:19020303] [PUBMED:9618481] [PUBMED:12809600] [PUBMED:8242749] [PUBMED:10385618] [PUBMED:17426725] [PUBMED:17018296] [PUBMED:16212951] [PUBMED:12925736] [PUBMED:11099028] [PUBMED:15568976] [PUBMED:15838516] [PUBMED:15838523] [PUBMED:15876871] [PUBMED:7908906] [PUBMED:9889196]
Cellular Senescence [NCBI:1270426] [REACTOME:R-HSA-2559583] [PUBMED:21078816] [PUBMED:18711403] [PUBMED:22048312] [PUBMED:19818705] [PUBMED:17662938] [PUBMED:23746838] [PUBMED:9282108] [PUBMED:17667954] [PUBMED:13905658]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Cyclin D associated events in G1 [NCBI:1269767] [REACTOME:R-HSA-69231]
Direct p53 effectors [NCBI:137939] [Pathway Interaction Database:p53downstreampathway] [PUBMED:7479001] [PUBMED:19626115] [PUBMED:10692390] [PUBMED:15289308] [PUBMED:14688482] [PUBMED:16301995] [PUBMED:11850816] [PUBMED:12370809] [PUBMED:16260627] [PUBMED:15186775] [PUBMED:15580302] [PUBMED:10748162] [PUBMED:10919640] [PUBMED:19011621] [PUBMED:12438652] [PUBMED:11559530] [PUBMED:11641774] [PUBMED:11971958] [PUBMED:9659898] [PUBMED:9343394] [PUBMED:10716435] [PUBMED:17146433] [PUBMED:17719542] [PUBMED:17938176] [PUBMED:17409421] [PUBMED:11032029] [PUBMED:15781865] [PUBMED:11463392] [PUBMED:9736732] [PUBMED:17268548] [PUBMED:8570655] [PUBMED:18046411] [PUBMED:12944906] [PUBMED:16249378] [PUBMED:15273740] [PUBMED:15598651] [PUBMED:10618379] [PUBMED:15958553] [PUBMED:17189187] [PUBMED:17145718] [PUBMED:11988847] [PUBMED:8119988] [PUBMED:12089322] [PUBMED:16286009] [PUBMED:12890671] [PUBMED:12402042] [PUBMED:10618714] [PUBMED:14730312] [PUBMED:12857899] [PUBMED:14963330] [PUBMED:11278953] [PUBMED:11973653] [PUBMED:12692263] [PUBMED:10984493] [PUBMED:10640990] [PUBMED:11545734] [PUBMED:16151013] [PUBMED:12372430] [PUBMED:16651407] [PUBMED:9891062] [PUBMED:12606722] [PUBMED:12453409] [PUBMED:15377670] [PUBMED:12667443] [PUBMED:17707234] [PUBMED:9920903] [PUBMED:14992722] [PUBMED:15790310] [PUBMED:15831478] [PUBMED:11314010] [PUBMED:10329733] [PUBMED:17264218] [PUBMED:11511362] [PUBMED:11919562] [PUBMED:11814693] [PUBMED:17554199] [PUBMED:18250150] [PUBMED:10518217] [PUBMED:10891498] [PUBMED:10973264] [PUBMED:15077116] [PUBMED:16230375] [PUBMED:18485870] [PUBMED:7796420] [PUBMED:15710382] [PUBMED:17409411] [PUBMED:8319905] [PUBMED:10684646] [PUBMED:7566179] [PUBMED:8887630] [PUBMED:11807984] [PUBMED:9841917] [PUBMED:12654245] [PUBMED:9023107] [PUBMED:15103385] [PUBMED:11684014] [PUBMED:17110336] [PUBMED:11278253] [PUBMED:14576823] [PUBMED:8418500] [PUBMED:11350971] [PUBMED:11840333] [PUBMED:7651818] [PUBMED:7651386] [PUBMED:15378026] [PUBMED:15607964] [PUBMED:11279192] [PUBMED:10777218] [PUBMED:15334053] [PUBMED:12138177] [PUBMED:9619826] [PUBMED:16278683] [PUBMED:17189186] [PUBMED:16140933] [PUBMED:10094469] [PUBMED:9926927] [PUBMED:17719541] [PUBMED:15735003] [PUBMED:12853982] [PUBMED:14707288] [PUBMED:10777207]
E2F mediated regulation of DNA replication [NCBI:1269774] [REACTOME:R-HSA-113510] [PUBMED:12393009] [PUBMED:12726857] [PUBMED:12473340]
E2F transcription factor network [NCBI:137934] [Pathway Interaction Database:e2f_pathway] [PUBMED:15175242] [PUBMED:11034215] [PUBMED:8832394] [PUBMED:7479977] [PUBMED:12077144] [PUBMED:11274364] [PUBMED:8618861] [PUBMED:11857079] [PUBMED:7958837] [PUBMED:15014447] [PUBMED:9774682] [PUBMED:9704927] [PUBMED:9271400] [PUBMED:8334989] [PUBMED:16288221] [PUBMED:10766737] [PUBMED:8657141] [PUBMED:8552092] [PUBMED:11101847] [PUBMED:12757710] [PUBMED:17704056] [PUBMED:7705662] [PUBMED:15897886] [PUBMED:9192872] [PUBMED:9778043] [PUBMED:12766778] [PUBMED:15510213] [PUBMED:11418595] [PUBMED:10454584] [PUBMED:10783242] [PUBMED:11904439] [PUBMED:16179649] [PUBMED:7791762] [PUBMED:11719808] [PUBMED:12389032] [PUBMED:8264596] [PUBMED:19491197] [PUBMED:15713665] [PUBMED:16357170] [PUBMED:9689056] [PUBMED:12748276] [PUBMED:2524830] [PUBMED:14633988] [PUBMED:12697828] [PUBMED:12101096] [PUBMED:11799067] [PUBMED:15133492] [PUBMED:16892051] [PUBMED:8943353] [PUBMED:9724731] [PUBMED:10030670] [PUBMED:11459832] [PUBMED:8114719] [PUBMED:9520412] [PUBMED:18348985] [PUBMED:9020173] [PUBMED:11389439] [PUBMED:16211008] [PUBMED:12411495] [PUBMED:7958836] [PUBMED:12909625] [PUBMED:15306814] [PUBMED:10688648] [PUBMED:12611887] [PUBMED:9191053] [PUBMED:10373518] [PUBMED:10187822]
G0 and Early G1 [NCBI:1269765] [REACTOME:R-HSA-1538133]
G1 Phase [NCBI:1269766] [REACTOME:R-HSA-69236]
G1/S Transition [NCBI:1269768] [REACTOME:R-HSA-69206]
G1/S-Specific Transcription [NCBI:1269772] [REACTOME:R-HSA-69205]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Inhibition of replication initiation of damaged DNA by RB1/E2F1 [NCBI:1269775] [REACTOME:R-HSA-113501]
Intrinsic Pathway for Apoptosis [NCBI:1270268] [REACTOME:R-HSA-109606] [PUBMED:12042762] [PUBMED:11711427] [PUBMED:15077149]
Mitotic G1-G1/S phases [NCBI:1269764] [REACTOME:R-HSA-453279]
Oncogene Induced Senescence [NCBI:1270427] [REACTOME:R-HSA-2559585] [PUBMED:10722742] [PUBMED:20583212] [PUBMED:8521522] [PUBMED:20534573] [PUBMED:11234019] [PUBMED:14729966] [PUBMED:12839923] [PUBMED:8319905] [PUBMED:18365017] [PUBMED:15572696] [PUBMED:9529249] [PUBMED:10733595] [PUBMED:9824166] [PUBMED:11782450] [PUBMED:8259215] [PUBMED:7588608] [PUBMED:8552081] [PUBMED:9704925] [PUBMED:22336108] [PUBMED:11883935]
Oxidative Stress Induced Senescence [NCBI:1270428] [REACTOME:R-HSA-2559580] [PUBMED:17344414] [PUBMED:17332741] [PUBMED:8622688] [PUBMED:7588633] [PUBMED:15563468] [PUBMED:15287722] [PUBMED:11062067] [PUBMED:16337592] [PUBMED:14532106] [PUBMED:17254968] [PUBMED:15866172] [PUBMED:9628874] [PUBMED:12171911] [PUBMED:7816143] [PUBMED:22020331] [PUBMED:11564866] [PUBMED:9162092] [PUBMED:8974401] [PUBMED:19451217] [PUBMED:12808055] [PUBMED:17210787] [PUBMED:8846784] [PUBMED:19462008] [PUBMED:12134156] [PUBMED:8626550] [PUBMED:8774846] [PUBMED:12189133] [PUBMED:9195981] [PUBMED:8622669] [PUBMED:8259215] [PUBMED:19528227] [PUBMED:9564042] [PUBMED:9529249] [PUBMED:16436515] [PUBMED:19451218] [PUBMED:17395714] [PUBMED:9030721] [PUBMED:12435631] [PUBMED:22325352]
Pre-NOTCH Expression and Processing [NCBI:1269531] [REACTOME:R-HSA-1912422] [PUBMED:21490058] [PUBMED:20805998] [PUBMED:21464368] [PUBMED:9187150] [PUBMED:11707585] [PUBMED:10669757] [PUBMED:9244302] [PUBMED:20080834] [PUBMED:18347015] [PUBMED:19773441] [PUBMED:9207795] [PUBMED:10935637] [PUBMED:19714243] [PUBMED:18243100] [PUBMED:19723635] [PUBMED:11524432] [PUBMED:9727485] [PUBMED:12486116] [PUBMED:20495621] [PUBMED:10935626] [PUBMED:20351093] [PUBMED:19701457] [PUBMED:21602795] [PUBMED:21551231] [PUBMED:9653148]
Pre-NOTCH Transcription and Translation [NCBI:1269532] [REACTOME:R-HSA-1912408] [PUBMED:9693032] [PUBMED:19773441] [PUBMED:20080834] [PUBMED:20351093] [PUBMED:10545110] [PUBMED:20495621] [PUBMED:19714243] [PUBMED:17823410] [PUBMED:19723635] [PUBMED:17554337] [PUBMED:21602795] [PUBMED:21551231] [PUBMED:1425352] [PUBMED:16773578] [PUBMED:17540598] [PUBMED:7698746] [PUBMED:20805998] [PUBMED:11187898] [PUBMED:1831692] [PUBMED:1764995] [PUBMED:8878478] [PUBMED:17540599]
Programmed Cell Death [NCBI:1270261] [REACTOME:R-HSA-5357801] [PUBMED:25236395]
Regulation of nuclear SMAD2/3 signaling [NCBI:137963] [Pathway Interaction Database:smad2_3nuclearpathway] [PUBMED:15009097] [PUBMED:11790301] [PUBMED:11836524] [PUBMED:10995736] [PUBMED:11114293] [PUBMED:10973944] [PUBMED:10022869] [PUBMED:11058129] [PUBMED:9722503] [PUBMED:12904571] [PUBMED:14993291] [PUBMED:11013220] [PUBMED:15363409] [PUBMED:9702197] [PUBMED:12718878] [PUBMED:11331591] [PUBMED:12167862] [PUBMED:14729983] [PUBMED:9707553] [PUBMED:10878024] [PUBMED:9679060] [PUBMED:10887155] [PUBMED:10199400] [PUBMED:12631740] [PUBMED:11555647] [PUBMED:15688032] [PUBMED:12150994] [PUBMED:12374795] [PUBMED:9606191] [PUBMED:9702198] [PUBMED:10518526] [PUBMED:10575014] [PUBMED:10485843] [PUBMED:11283614] [PUBMED:10722728] [PUBMED:10037600] [PUBMED:15241418] [PUBMED:14691252] [PUBMED:10748032] [PUBMED:12551947] [PUBMED:14671321] [PUBMED:11427533] [PUBMED:11711431] [PUBMED:10531362] [PUBMED:11571228] [PUBMED:10085140] [PUBMED:17478422] [PUBMED:15044954] [PUBMED:10964912] [PUBMED:11707452] [PUBMED:11801598] [PUBMED:17074756] [PUBMED:12226080] [PUBMED:10557285] [PUBMED:10843994] [PUBMED:15084259] [PUBMED:10531062] [PUBMED:16959612] [PUBMED:9679056] [PUBMED:10652350] [PUBMED:9618481] [PUBMED:11927558] [PUBMED:9732876]
Regulation of retinoblastoma protein [NCBI:137916] [Pathway Interaction Database:rb_1pathway] [PUBMED:15469821] [PUBMED:11470869] [PUBMED:8493578] [PUBMED:7596417] [PUBMED:8449399] [PUBMED:9468140] [PUBMED:11596110] [PUBMED:9545246] [PUBMED:16360038] [PUBMED:14673169] [PUBMED:17991896] [PUBMED:8805225] [PUBMED:7926730] [PUBMED:10322110] [PUBMED:11533237] [PUBMED:1828393] [PUBMED:8657117] [PUBMED:9491888] [PUBMED:7877691] [PUBMED:14729964] [PUBMED:1710781] [PUBMED:10778858] [PUBMED:11566021] [PUBMED:8246996] [PUBMED:12450794] [PUBMED:16374512] [PUBMED:10783144] [PUBMED:15949438] [PUBMED:9468139] [PUBMED:8242749] [PUBMED:9464541] [PUBMED:1531329] [PUBMED:9819434] [PUBMED:12479814] [PUBMED:10888886] [PUBMED:10597288] [PUBMED:8626527] [PUBMED:7629134] [PUBMED:11545733] [PUBMED:17620057] [PUBMED:11433299] [PUBMED:9858607] [PUBMED:15716956] [PUBMED:10490602] [PUBMED:1828392] [PUBMED:15577944] [PUBMED:11484059] [PUBMED:11583618] [PUBMED:10499802]
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription [NCBI:1269528] [REACTOME:R-HSA-2173796] [PUBMED:22275377] [PUBMED:18568018] [PUBMED:15150273] [PUBMED:10934479] [PUBMED:11294908] [PUBMED:12592392] [PUBMED:10022869] [PUBMED:14657019] [PUBMED:11013220] [PUBMED:11274402] [PUBMED:19914168] [PUBMED:12150994]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by NOTCH [NCBI:1269530] [REACTOME:R-HSA-157118]
Signaling by TGF-beta Receptor Complex [NCBI:1269523] [REACTOME:R-HSA-170834] [PUBMED:19648010]
TGF-beta signaling pathway [NCBI:83064] [KEGG:hsa04350] [PUBMED:11836504] [PUBMED:14534577] [PUBMED:10021351] [PUBMED:12809600] [PUBMED:14557817] [PUBMED:14769828] [PUBMED:10519551] [PUBMED:12163231] [PUBMED:19758997] [PUBMED:12466190] [PUBMED:11252746] [PUBMED:15063168] [PUBMED:9847239] [PUBMED:11252892]
TP53 Regulates Transcription of Cell Cycle Genes [NCBI:1383071] [REACTOME:R-HSA-6791312] [PUBMED:12897130] [PUBMED:11896574] [PUBMED:18337750] [PUBMED:24739573] [PUBMED:9184226] [PUBMED:8242751] [PUBMED:11812999] [PUBMED:11574543] [PUBMED:22172947] [PUBMED:17719541] [PUBMED:20460379] [PUBMED:22802529] [PUBMED:9671765] [PUBMED:11814693] [PUBMED:16160013] [PUBMED:23485469] [PUBMED:26122615] [PUBMED:23236473] [PUBMED:22802528] [PUBMED:9712883] [PUBMED:7784094] [PUBMED:20531387] [PUBMED:9780002] [PUBMED:10891498] [PUBMED:22252318] [PUBMED:19276069] [PUBMED:20817677] [PUBMED:14968113] [PUBMED:18431400] [PUBMED:20352051] [PUBMED:12692263] [PUBMED:18719709] [PUBMED:16140933] [PUBMED:7973727] [PUBMED:10524633] [PUBMED:15574328] [PUBMED:24096481] [PUBMED:15186775] [PUBMED:16772293] [PUBMED:8242752] [PUBMED:8944033] [PUBMED:17146433] [PUBMED:9659898]
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest [NCBI:1383073] [REACTOME:R-HSA-6804114] [PUBMED:7784094] [PUBMED:23485469] [PUBMED:15186775] [PUBMED:15574328] [PUBMED:16772293] [PUBMED:10524633] [PUBMED:9659898] [PUBMED:20460379] [PUBMED:11574543] [PUBMED:7973727] [PUBMED:24096481] [PUBMED:17719541]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer [NCBI:1269527] [REACTOME:R-HSA-2173793] [PUBMED:12150994] [PUBMED:16751101] [PUBMED:10199400] [PUBMED:18568018] [PUBMED:19135894] [PUBMED:10531062]