full name
growth arrest specific 6

synonyms
AXLLG, AXSF, GAS6, ENSG00000183087

HGNC
HGNC:4168

Entrez Gene
Gene:2621

ENSEMBL
ENSG00000183087

location
chr: 13
start: 114523522
stop: 114567046
strand: -

transcripts
NM_000820.2
NM_001143945.1
NM_001143946.1

pathways
Cell surface interactions at the vascular wall [NCBI:1269373] [REACTOME:R-HSA-202733] [PUBMED:17525755] [PUBMED:11282294] [PUBMED:10798271] [PUBMED:8578462] [PUBMED:14615387] [PUBMED:16115029]
EGFR tyrosine kinase inhibitor resistance [NCBI:1404798] [KEGG:hsa01521] [PUBMED:16843264] [PUBMED:23401451] [PUBMED:20966921] [PUBMED:24307395] [PUBMED:22956644] [PUBMED:25232485] [PUBMED:24493829] [PUBMED:23071030] [PUBMED:18483355] [PUBMED:24202392] [PUBMED:19632948] [PUBMED:23361103] [PUBMED:26579470] [PUBMED:22970367] [PUBMED:23358468] [PUBMED:17554333] [PUBMED:25337673] [PUBMED:22474259] [PUBMED:20551942]
Gamma carboxylation, hypusine formation and arylsulfatase activation [NCBI:1268702] [REACTOME:R-HSA-163841]
Gamma-carboxylation of protein precursors [NCBI:1268704] [REACTOME:R-HSA-159740] [PUBMED:10917896] [PUBMED:10068650] [PUBMED:11071668] [PUBMED:11513608] [PUBMED:9845520]
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins [NCBI:1268703] [REACTOME:R-HSA-159854]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Platelet activation, signaling and aggregation [NCBI:1269350] [REACTOME:R-HSA-76002] [PUBMED:16543958] [PUBMED:8704248] [PUBMED:2018971] [PUBMED:1672265] [PUBMED:17059469] [PUBMED:12681240] [PUBMED:12411949] [PUBMED:11511514]
Platelet degranulation [NCBI:1269367] [REACTOME:R-HSA-114608] [PUBMED:14630798]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Removal of aminoterminal propeptides from gamma-carboxylated proteins [NCBI:1268706] [REACTOME:R-HSA-159782] [PUBMED:8846780] [PUBMED:1629222] [PUBMED:8473289] [PUBMED:9108399] [PUBMED:8463288]
Response to elevated platelet cytosolic Ca2+ [NCBI:1269365] [REACTOME:R-HSA-76005] [PUBMED:8424766]
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus [NCBI:1268705] [REACTOME:R-HSA-159763] [PUBMED:11252894]