Logo
full name
glutathione peroxidase 2

synonyms
GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPx-2, GSHPX-GI, GPX2, ENSG00000176153

HGNC
HGNC:4554

Entrez Gene
Gene:2877

ENSEMBL
ENSG00000176153

location
chr: 14
start: 65405870
stop: 65409623
strand: -

transcripts
NM_002083.3
NR_046320.1
NR_046321.1

pathways
Arachidonic acid metabolism [NCBI:82991] [KEGG:hsa00590] [NCBI:1270087] [REACTOME:R-HSA-2142753] [PUBMED:14622984] [PUBMED:15292194] [PUBMED:10908295] [PUBMED:15205388] [PUBMED:9812980] [PUBMED:14660610] [PUBMED:11328810] [PUBMED:14636671] [PUBMED:14626496] [PUBMED:11679404] [PUBMED:19244215]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Detoxification of Reactive Oxygen Species [NCBI:1270420] [REACTOME:R-HSA-3299685] [PUBMED:23469953] [PUBMED:23268465] [PUBMED:20064600] [PUBMED:22286106] [PUBMED:21473702] [PUBMED:22196163] [PUBMED:21375475] [PUBMED:19061483] [PUBMED:21453242]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Glutathione metabolism [NCBI:82973] [KEGG:hsa00480] [PUBMED:18395526] [PUBMED:15537651] [PUBMED:12466271] [PUBMED:9677355] [PUBMED:11157967] [PUBMED:12675513] [PUBMED:18482986] [PUBMED:8892297] [PUBMED:12751784] [PUBMED:12750367] [PUBMED:14982633] [PUBMED:11150302] [PUBMED:12121990] [PUBMED:15610825] [PUBMED:17922848] [PUBMED:12049631] [PUBMED:12949079] [PUBMED:7813456] [PUBMED:9851611] [PUBMED:6798961] [PUBMED:10713147] [PUBMED:12967709] [PUBMED:14583094] [PUBMED:12446213]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Synthesis of 12-eicosatetraenoic acid derivatives [NCBI:1270092] [REACTOME:R-HSA-2142712] [PUBMED:19244215]
Synthesis of 15-eicosatetraenoic acid derivatives [NCBI:1270091] [REACTOME:R-HSA-2142770] [PUBMED:19244215]
Synthesis of 5-eicosatetraenoic acids [NCBI:1270090] [REACTOME:R-HSA-2142688] [PUBMED:19244215]
TP53 Regulates Metabolic Genes [NCBI:1269655] [REACTOME:R-HSA-5628897] [PUBMED:19822145] [PUBMED:12453409] [PUBMED:18344994] [PUBMED:11545734] [PUBMED:16839880] [PUBMED:20399660] [PUBMED:15105503] [PUBMED:13298683] [PUBMED:15665293] [PUBMED:18198340] [PUBMED:18692468] [PUBMED:12203114] [PUBMED:17409411] [PUBMED:11959846] [PUBMED:16728594] [PUBMED:17486094] [PUBMED:23484829] [PUBMED:22682249] [PUBMED:19696408] [PUBMED:9926927] [PUBMED:22864287] [PUBMED:20378837] [PUBMED:18391940] [PUBMED:24366874] [PUBMED:19439913] [PUBMED:15059920] [PUBMED:10716435] [PUBMED:17540029]
Thyroid hormone synthesis [NCBI:835410] [KEGG:hsa04918] [PUBMED:21448409] [PUBMED:9086577] [PUBMED:21986207] [PUBMED:11137035] [PUBMED:17666482] [PUBMED:20407074] [PUBMED:20093166] [PUBMED:20122987] [PUBMED:15611820] [PUBMED:20378719] [PUBMED:23438835] [PUBMED:11717564] [PUBMED:16870170] [PUBMED:19196800] [PUBMED:9538302] [PUBMED:11029276] [PUBMED:20167242] [PUBMED:10893432] [PUBMED:21683758]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]
glutathione redox reactions I [NCBI:142227] [BIOCYC:HUMAN_PWY-4081] [PUBMED:12761212]
reactive oxygen species degradation [NCBI:1108784] [BIOCYC:HUMAN_DETOX1-PWY-1] [PUBMED:2853161] [PUBMED:11997379] [PUBMED:9214587] [PUBMED:10666617] [PUBMED:10638941] [PUBMED:9765550] [PUBMED:24511533]