Logo
full name
heat shock protein 90 alpha family class A member 1

synonyms
EL52, HSP86, Hsp89, HSP89A, Hsp90, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, LAP2, HSP90AA1, ENSG00000080824

HGNC
HGNC:5253

Entrez Gene
Gene:3320

ENSEMBL
ENSG00000080824

location
chr: 14
start: 102547075
stop: 102606086
strand: -

transcripts
NM_001017963.2
NM_005348.3

pathways
AURKA Activation by TPX2 [NCBI:1383018] [REACTOME:R-HSA-8854518] [PUBMED:14580337] [PUBMED:21147853] [PUBMED:22094468] [PUBMED:21347367]
Anchoring of the basal body to the plasma membrane [NCBI:1268847] [REACTOME:R-HSA-5620912] [PUBMED:21816947] [PUBMED:23747070] [PUBMED:19575670] [PUBMED:13978319] [PUBMED:23348840] [PUBMED:25047614] [PUBMED:20819941] [PUBMED:5661997] [PUBMED:21422230] [PUBMED:24469809] [PUBMED:23530209] [PUBMED:21725307] [PUBMED:21680046] [PUBMED:23351793] [PUBMED:21427764] [PUBMED:11676918] [PUBMED:22653444]
Antigen processing and presentation [NCBI:83074] [KEGG:hsa04612] [PUBMED:12776207] [PUBMED:15653315] [PUBMED:15814328] [PUBMED:20010787] [PUBMED:15224094] [PUBMED:15745856] [PUBMED:11244040] [PUBMED:15304636] [PUBMED:11905820] [PUBMED:16181333] [PUBMED:16200082] [PUBMED:15653312] [PUBMED:15224093] [PUBMED:15771591] [PUBMED:12974477]
Attenuation phase [NCBI:1270424] [REACTOME:R-HSA-3371568] [PUBMED:1936996]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Binding and Uptake of Ligands by Scavenger Receptors [NCBI:1269897] [REACTOME:R-HSA-2173782] [PUBMED:16511968] [PUBMED:15904923] [PUBMED:218198] [PUBMED:19388903] [PUBMED:19659436]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cellular response to heat stress [NCBI:1270421] [REACTOME:R-HSA-3371556] [PUBMED:8455624] [PUBMED:8441385]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Centrosome maturation [NCBI:1269805] [REACTOME:R-HSA-380287] [PUBMED:17178454] [PUBMED:18437411]
Cilium Assembly [NCBI:1268846] [REACTOME:R-HSA-5617833] [PUBMED:21427764] [PUBMED:23351793] [PUBMED:25040720] [PUBMED:17955020] [PUBMED:22118932] [PUBMED:22653444] [PUBMED:22389062] [PUBMED:20399632] [PUBMED:25047619] [PUBMED:20395968] [PUBMED:23945166] [PUBMED:19575670] [PUBMED:24296415] [PUBMED:20145001] [PUBMED:19602418]
Class I PI3K signaling events [NCBI:138022] [Pathway Interaction Database:pi3kcipathway] [PUBMED:9072969] [PUBMED:15296756] [PUBMED:12780340] [PUBMED:11154281] [PUBMED:9326591] [PUBMED:10357815] [PUBMED:10586033] [PUBMED:9824312] [PUBMED:11001876] [PUBMED:9593664] [PUBMED:10770799] [PUBMED:9442017] [PUBMED:8643691] [PUBMED:7627555] [PUBMED:11102801] [PUBMED:9307042] [PUBMED:10506192] [PUBMED:11804589] [PUBMED:15879121] [PUBMED:11226282] [PUBMED:18024423] [PUBMED:8629002] [PUBMED:9550703] [PUBMED:14688341] [PUBMED:16418224] [PUBMED:8945478] [PUBMED:10333475] [PUBMED:10764758] [PUBMED:9417041] [PUBMED:8052307]
Class I PI3K signaling events mediated by Akt [NCBI:138020] [Pathway Interaction Database:pi3kciaktpathway] [PUBMED:10102273] [PUBMED:9812896] [PUBMED:15718470] [PUBMED:10485710] [PUBMED:16919458] [PUBMED:16213228] [PUBMED:11154276] [PUBMED:16962653] [PUBMED:9346240] [PUBMED:12244301] [PUBMED:15057270] [PUBMED:10217147] [PUBMED:17407381] [PUBMED:8524413] [PUBMED:16982699] [PUBMED:12637568] [PUBMED:18024423] [PUBMED:10358075] [PUBMED:9637919] [PUBMED:12244302] [PUBMED:9094314] [PUBMED:10576741] [PUBMED:11864996] [PUBMED:11777915] [PUBMED:12244303] [PUBMED:9381178] [PUBMED:11231573] [PUBMED:10949026] [PUBMED:15262962] [PUBMED:9512493] [PUBMED:10783894]
Constitutive Signaling by EGFRvIII [NCBI:1268860] [REACTOME:R-HSA-5637810]
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants [NCBI:1268858] [REACTOME:R-HSA-1236382]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Downregulation of ERBB2 signaling [NCBI:1457793] [REACTOME:R-HSA-8863795] [PUBMED:19933325] [PUBMED:21376233] [PUBMED:17210635] [PUBMED:12239347] [PUBMED:25081058]
EPH-Ephrin signaling [NCBI:1270330] [REACTOME:R-HSA-2682334] [PUBMED:18281458] [PUBMED:22120527]
EPHA-mediated growth cone collapse [NCBI:1270331] [REACTOME:R-HSA-3928663] [PUBMED:17300218] [PUBMED:15093606] [PUBMED:15469835] [PUBMED:15848799] [PUBMED:15928710] [PUBMED:11336673]
ErbB receptor signaling network [NCBI:138016] [Pathway Interaction Database:erbb_network_pathway] [PUBMED:19173594] [PUBMED:1688559] [PUBMED:6265789] [PUBMED:8188716] [PUBMED:9029149] [PUBMED:15192046] [PUBMED:6090945] [PUBMED:9618494] [PUBMED:9135143] [PUBMED:14661053] [PUBMED:7929212] [PUBMED:7902537] [PUBMED:18782861] [PUBMED:10348342] [PUBMED:7991602] [PUBMED:7515147] [PUBMED:1706616] [PUBMED:6254071] [PUBMED:2466334] [PUBMED:17684490] [PUBMED:10353604] [PUBMED:9130710] [PUBMED:12466964] [PUBMED:8617750] [PUBMED:3261240] [PUBMED:9419975] [PUBMED:7518560] [PUBMED:2543678] [PUBMED:9168114] [PUBMED:6315706] [PUBMED:16946702] [PUBMED:219373] [PUBMED:7679104] [PUBMED:8570211] [PUBMED:10527633] [PUBMED:17646177] [PUBMED:18721752] [PUBMED:9105049] [PUBMED:7929151] [PUBMED:8045292] [PUBMED:15568014] [PUBMED:11071886] [PUBMED:8702723] [PUBMED:9556621] [PUBMED:10722704] [PUBMED:17389679] [PUBMED:9275162] [PUBMED:9168115] [PUBMED:10214951] [PUBMED:1840698] [PUBMED:7509075]
Estrogen signaling pathway [NCBI:799177] [KEGG:hsa04915] [PUBMED:15695368] [PUBMED:16112267] [PUBMED:9278514] [PUBMED:19187465] [PUBMED:12421825] [PUBMED:12650715] [PUBMED:18253054] [PUBMED:16516516] [PUBMED:14573532] [PUBMED:18755790] [PUBMED:18538919] [PUBMED:19767412] [PUBMED:14993035] [PUBMED:19549587] [PUBMED:15862823] [PUBMED:20694192] [PUBMED:19464786] [PUBMED:21779010] [PUBMED:16270355] [PUBMED:21742056] [PUBMED:19700741] [PUBMED:21844907]
Fcgamma receptor (FCGR) dependent phagocytosis [NCBI:1269279] [REACTOME:R-HSA-2029480] [PUBMED:8541526] [PUBMED:12488490] [PUBMED:16413920] [PUBMED:17050193]
Fluid shear stress and atherosclerosis [NCBI:1474302] [KEGG:hsa05418] [PUBMED:23429585] [PUBMED:21050140] [PUBMED:17599600] [PUBMED:24190880] [PUBMED:22003002] [PUBMED:24876354] [PUBMED:24947523] [PUBMED:23899566] [PUBMED:26597822] [PUBMED:20353494] [PUBMED:22076424] [PUBMED:20538799] [PUBMED:25165867] [PUBMED:20032497] [PUBMED:23084990] [PUBMED:26822720] [PUBMED:24573382] [PUBMED:23555159] [PUBMED:26212910] [PUBMED:21457103] [PUBMED:19151844] [PUBMED:15388638] [PUBMED:16765337] [PUBMED:27027326] [PUBMED:25638487] [PUBMED:21733876]
G2/M Transition [NCBI:1269799] [REACTOME:R-HSA-69275]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Gene Silencing by RNA [NCBI:1269719] [REACTOME:R-HSA-211000] [PUBMED:15741316] [PUBMED:25565029] [PUBMED:19165215] [PUBMED:21755468] [PUBMED:16510870] [PUBMED:19412884] [PUBMED:17560368] [PUBMED:19239886]
Glucocorticoid receptor regulatory network [NCBI:138014] [Pathway Interaction Database:reg_gr_pathway] [PUBMED:8943293] [PUBMED:1708774] [PUBMED:15826950] [PUBMED:11027313] [PUBMED:12118039] [PUBMED:9388207] [PUBMED:11751894] [PUBMED:12151000] [PUBMED:9765258] [PUBMED:9407028] [PUBMED:19074285] [PUBMED:2838908] [PUBMED:15817653] [PUBMED:9722596] [PUBMED:12917342] [PUBMED:1387550] [PUBMED:10974006] [PUBMED:15790729] [PUBMED:10825196] [PUBMED:10623828] [PUBMED:2169352] [PUBMED:9315653] [PUBMED:7759501] [PUBMED:8290595] [PUBMED:2905764] [PUBMED:12351702] [PUBMED:11080152] [PUBMED:8428574] [PUBMED:9215863] [PUBMED:15459252] [PUBMED:10400612] [PUBMED:9426156] [PUBMED:17440046] [PUBMED:18838540] [PUBMED:2169353] [PUBMED:10820245] [PUBMED:12511605] [PUBMED:2586521] [PUBMED:1740658] [PUBMED:11555652] [PUBMED:11562347] [PUBMED:9482836] [PUBMED:18337589] [PUBMED:10958685] [PUBMED:9388192] [PUBMED:15834420] [PUBMED:15657031] [PUBMED:8878484] [PUBMED:10760263] [PUBMED:12730237] [PUBMED:8702844] [PUBMED:2169351] [PUBMED:17215482] [PUBMED:8898375]
HSF1 activation [NCBI:1270422] [REACTOME:R-HSA-3371511] [PUBMED:7623826] [PUBMED:8631933]
HSF1-dependent transactivation [NCBI:1270423] [REACTOME:R-HSA-3371571] [PUBMED:7623826]
Hypoxic and oxygen homeostasis regulation of HIF-1-alpha [NCBI:138056] [Pathway Interaction Database:hif1apathway] [PUBMED:16182248] [PUBMED:7539918] [PUBMED:14764593] [PUBMED:9537326] [PUBMED:12080085] [PUBMED:11292862] [PUBMED:11641274] [PUBMED:10353251] [PUBMED:12052835] [PUBMED:8663540] [PUBMED:10973499] [PUBMED:8816435] [PUBMED:9653127] [PUBMED:11707426] [PUBMED:15721254] [PUBMED:11595184] [PUBMED:12042299] [PUBMED:10878807] [PUBMED:12464182] [PUBMED:17244529] [PUBMED:9822602] [PUBMED:11292861] [PUBMED:11598268] [PUBMED:11382768] [PUBMED:11823643] [PUBMED:17382325]
IL-17 signaling pathway [NCBI:1474301] [KEGG:hsa04657] [PUBMED:17921324] [PUBMED:24011563] [PUBMED:21349428] [PUBMED:20383173] [PUBMED:20514051] [PUBMED:20177959] [PUBMED:18178098] [PUBMED:21074482] [PUBMED:21130872] [PUBMED:17027518] [PUBMED:23917206] [PUBMED:23116200] [PUBMED:18701318] [PUBMED:26252407] [PUBMED:22851696] [PUBMED:21155836] [PUBMED:25145755] [PUBMED:17177681] [PUBMED:19575028] [PUBMED:23557798] [PUBMED:21852080] [PUBMED:22324470]
IL2 signaling events mediated by PI3K [NCBI:137938] [Pathway Interaction Database:il2_pi3kpathway] [PUBMED:15271800] [PUBMED:8617294] [PUBMED:7543780] [PUBMED:9092570] [PUBMED:9162082] [PUBMED:7737351] [PUBMED:9108028] [PUBMED:11486019] [PUBMED:1614535] [PUBMED:15843522] [PUBMED:7760801] [PUBMED:9029085] [PUBMED:1652056] [PUBMED:11994454] [PUBMED:12393431] [PUBMED:9771966] [PUBMED:10373522] [PUBMED:12525482] [PUBMED:3523754] [PUBMED:7736574] [PUBMED:10982827] [PUBMED:7589144] [PUBMED:7528328]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Influenza Infection [NCBI:1269108] [REACTOME:R-HSA-168254]
Influenza Life Cycle [NCBI:1269109] [REACTOME:R-HSA-168255]
Influenza Viral RNA Transcription and Replication [NCBI:1269115] [REACTOME:R-HSA-168273] [PUBMED:2214032] [PUBMED:6863242] [PUBMED:6616622] [PUBMED:6269803]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Integrins in angiogenesis [NCBI:137999] [Pathway Interaction Database:avb3_integrin_pathway] [PUBMED:10837460] [PUBMED:9182576] [PUBMED:12642872] [PUBMED:15711558] [PUBMED:10037797] [PUBMED:10196194] [PUBMED:11877390] [PUBMED:16418218] [PUBMED:16600665] [PUBMED:16982628] [PUBMED:15479743] [PUBMED:16720645] [PUBMED:11684710] [PUBMED:10821695] [PUBMED:12237112] [PUBMED:12750158] [PUBMED:11551924] [PUBMED:8794870] [PUBMED:10022831] [PUBMED:15187087] [PUBMED:16195423] [PUBMED:16760434] [PUBMED:12682293] [PUBMED:9420328] [PUBMED:15247219] [PUBMED:9490736] [PUBMED:11313365]
Interleukin-4 and 13 signaling [NCBI:1470923] [REACTOME:R-HSA-6785807] [PUBMED:12704343] [PUBMED:10358772]
LKB1 signaling events [NCBI:137957] [Pathway Interaction Database:lkb1_pathway] [PUBMED:12429843] [PUBMED:18339622] [PUBMED:16912160] [PUBMED:15454081] [PUBMED:19513107] [PUBMED:16959574] [PUBMED:11741830] [PUBMED:7706316] [PUBMED:18063805] [PUBMED:14614828] [PUBMED:16306228] [PUBMED:12489981] [PUBMED:19386264] [PUBMED:18439900] [PUBMED:12805220] [PUBMED:17959818] [PUBMED:16396636] [PUBMED:10542369] [PUBMED:16308421] [PUBMED:15016379] [PUBMED:19622832] [PUBMED:14511394] [PUBMED:14676191] [PUBMED:17482548] [PUBMED:17991864] [PUBMED:11445556] [PUBMED:14651849] [PUBMED:14517248] [PUBMED:14985505] [PUBMED:15261145] [PUBMED:16817901] [PUBMED:9108484] [PUBMED:17573348] [PUBMED:12973359] [PUBMED:19369417] [PUBMED:15705853] [PUBMED:10642527] [PUBMED:16627617] [PUBMED:17482549] [PUBMED:8631898] [PUBMED:14976552]
Loss of Nlp from mitotic centrosomes [NCBI:1269809] [REACTOME:R-HSA-380259] [PUBMED:12852856]
Loss of proteins required for interphase microtubule organization from the centrosome [NCBI:1269808] [REACTOME:R-HSA-380284] [PUBMED:12140259] [PUBMED:12852856]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of nitric oxide [NCBI:1270115] [REACTOME:R-HSA-202131] [PUBMED:17237348]
Mitotic G2-G2/M phases [NCBI:1269797] [REACTOME:R-HSA-453274]
NOD-like receptor signaling pathway [NCBI:122191] [KEGG:hsa04621] [PUBMED:25330206] [PUBMED:21575908] [PUBMED:23846113] [PUBMED:26549800] [PUBMED:16493424] [PUBMED:23124073] [PUBMED:24840700] [PUBMED:27291964] [PUBMED:27012466] [PUBMED:24707857] [PUBMED:19767725] [PUBMED:25879280] [PUBMED:23215645] [PUBMED:22819539] [PUBMED:23702978] [PUBMED:20643110] [PUBMED:25879288] [PUBMED:26655628] [PUBMED:25145756] [PUBMED:24718315] [PUBMED:26482951] [PUBMED:25526305] [PUBMED:26121197] [PUBMED:22430786]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Organelle biogenesis and maintenance [NCBI:1268838] [REACTOME:R-HSA-1852241] [PUBMED:8608592] [PUBMED:16103713]
PI3K-Akt signaling pathway [NCBI:692234] [KEGG:hsa04151] [PUBMED:12048182] [PUBMED:11357143] [PUBMED:21440011] [PUBMED:15209374] [PUBMED:12669022] [PUBMED:18842113] [PUBMED:16847462] [PUBMED:12660731] [PUBMED:17360849] [PUBMED:9838078] [PUBMED:15505410] [PUBMED:16248975] [PUBMED:12531180] [PUBMED:21779440] [PUBMED:16187290] [PUBMED:15784165] [PUBMED:21620960]
PIWI-interacting RNA (piRNA) biogenesis [NCBI:1269724] [REACTOME:R-HSA-5601884] [PUBMED:23980886] [PUBMED:23124062] [PUBMED:23829526] [PUBMED:21427766] [PUBMED:22221002] [PUBMED:23166399] [PUBMED:18282709]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Progesterone-mediated oocyte maturation [NCBI:119304] [KEGG:hsa04914] [PUBMED:10497333] [PUBMED:12084906] [PUBMED:12045215] [PUBMED:11063930] [PUBMED:12477927] [PUBMED:11148128] [PUBMED:11730319] [PUBMED:12374568]
Prostate cancer [NCBI:83111] [KEGG:hsa05215] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11527574] [PUBMED:11750244] [PUBMED:16551847] [PUBMED:10835690] [PUBMED:8069858] [PUBMED:15724144] [PUBMED:10453277] [PUBMED:15082523] [PUBMED:9422516]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:20219571] [PUBMED:19491040] [PUBMED:20112977]
Recruitment of mitotic centrosome proteins and complexes [NCBI:1269806] [REACTOME:R-HSA-380270] [PUBMED:18437411] [PUBMED:17178454]
Regulation of Androgen receptor activity [NCBI:138027] [Pathway Interaction Database:ar_tf_pathway] [PUBMED:15650026] [PUBMED:17045208] [PUBMED:10364196] [PUBMED:16860317] [PUBMED:10611280] [PUBMED:10930412] [PUBMED:1525041] [PUBMED:10779504] [PUBMED:12514133] [PUBMED:1985913] [PUBMED:11931767] [PUBMED:17011549] [PUBMED:15640443] [PUBMED:16322096] [PUBMED:15923603] [PUBMED:14985354] [PUBMED:15743818] [PUBMED:12949936] [PUBMED:11994312] [PUBMED:10567371] [PUBMED:11875111] [PUBMED:15604291] [PUBMED:12890669] [PUBMED:14729952] [PUBMED:9211894] [PUBMED:9162033] [PUBMED:16705743] [PUBMED:16849544] [PUBMED:16923962] [PUBMED:11591700] [PUBMED:16051670] [PUBMED:8643509] [PUBMED:17108144] [PUBMED:16914734] [PUBMED:12682292] [PUBMED:3353726] [PUBMED:11585838] [PUBMED:16282370] [PUBMED:10381882] [PUBMED:15199155] [PUBMED:16455820] [PUBMED:14612401] [PUBMED:10625666] [PUBMED:17679089] [PUBMED:16461774]
Regulation of PLK1 Activity at G2/M Transition [NCBI:1269803] [REACTOME:R-HSA-2565942] [PUBMED:12207013] [PUBMED:18615013] [PUBMED:13678582] [PUBMED:18378770] [PUBMED:18566290] [PUBMED:18477460] [PUBMED:22365832]
Regulation of Telomerase [NCBI:137987] [Pathway Interaction Database:telomerasepathway] [PUBMED:12037663] [PUBMED:11191110] [PUBMED:15381700] [PUBMED:10637317] [PUBMED:15314656] [PUBMED:10601322] [PUBMED:12545159] [PUBMED:11110707] [PUBMED:15371341] [PUBMED:12681489] [PUBMED:15824061] [PUBMED:15048073] [PUBMED:10850490] [PUBMED:16730176] [PUBMED:12181313] [PUBMED:16890531] [PUBMED:9837921] [PUBMED:10224060] [PUBMED:15331176] [PUBMED:16522649] [PUBMED:9822378] [PUBMED:15316005] [PUBMED:12699629] [PUBMED:16843438] [PUBMED:12151407] [PUBMED:12135483] [PUBMED:15655249] [PUBMED:10888888] [PUBMED:16765199] [PUBMED:16869756] [PUBMED:10837221] [PUBMED:16135795] [PUBMED:11074006] [PUBMED:11191109] [PUBMED:14712220] [PUBMED:16508638] [PUBMED:10471503] [PUBMED:11854288] [PUBMED:16785237] [PUBMED:9130722] [PUBMED:12956959] [PUBMED:15710386] [PUBMED:12586360] [PUBMED:12377759] [PUBMED:11433024] [PUBMED:15843522] [PUBMED:14749375] [PUBMED:11274138] [PUBMED:12676087] [PUBMED:16166375] [PUBMED:15371412]
Regulation of actin dynamics for phagocytic cup formation [NCBI:1269281] [REACTOME:R-HSA-2029482] [PUBMED:17477841] [PUBMED:15452139] [PUBMED:15981459]
Scavenging by Class F Receptors [NCBI:1269901] [REACTOME:R-HSA-3000484] [PUBMED:19388903] [PUBMED:12154095]
Sema3A PAK dependent Axon repulsion [NCBI:1270309] [REACTOME:R-HSA-399954] [PUBMED:12593985] [PUBMED:11276226] [PUBMED:11604131] [PUBMED:18374575]
Semaphorin interactions [NCBI:1270304] [REACTOME:R-HSA-373755] [PUBMED:12593985] [PUBMED:12471249] [PUBMED:18269210] [PUBMED:16939971] [PUBMED:18374575]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR in Cancer [NCBI:1268856] [REACTOME:R-HSA-1643713]
Signaling by EGFRvIII in Cancer [NCBI:1268859] [REACTOME:R-HSA-5637812] [PUBMED:11087732]
Signaling by ERBB2 [NCBI:1269489] [REACTOME:R-HSA-1227986]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Signaling by Ligand-Responsive EGFR Variants in Cancer [NCBI:1268857] [REACTOME:R-HSA-5637815] [PUBMED:17177598] [PUBMED:16187797]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
Signaling events mediated by HDAC Class II [NCBI:138062] [Pathway Interaction Database:hdac_classii_pathway] [PUBMED:15916966] [PUBMED:10869435] [PUBMED:10898795] [PUBMED:16051668] [PUBMED:12032081] [PUBMED:12606581] [PUBMED:11804585] [PUBMED:11466315] [PUBMED:11567998] [PUBMED:16767219] [PUBMED:12024216] [PUBMED:16166628] [PUBMED:16221676] [PUBMED:11948178] [PUBMED:10220385] [PUBMED:12663674] [PUBMED:14668799] [PUBMED:16236793]
Signaling events mediated by VEGFR1 and VEGFR2 [NCBI:137940] [Pathway Interaction Database:vegfr1_2_pathway] [PUBMED:9398617] [PUBMED:9405464] [PUBMED:11494124] [PUBMED:12963813] [PUBMED:11756651] [PUBMED:10744763] [PUBMED:15060076] [PUBMED:9600074] [PUBMED:10376603] [PUBMED:11425855] [PUBMED:16337972] [PUBMED:12154000] [PUBMED:11978735] [PUBMED:10692392] [PUBMED:16763158] [PUBMED:10361126] [PUBMED:10748121] [PUBMED:12598525] [PUBMED:15026417] [PUBMED:11948691] [PUBMED:16966330] [PUBMED:16835467] [PUBMED:10409677] [PUBMED:10908731] [PUBMED:8903320] [PUBMED:15962004] [PUBMED:16633338] [PUBMED:11387210] [PUBMED:16839566] [PUBMED:11312102] [PUBMED:10207622] [PUBMED:16787925] [PUBMED:12171920] [PUBMED:12509223] [PUBMED:16760434] [PUBMED:14724572] [PUBMED:11704645] [PUBMED:12821150] [PUBMED:12881528] [PUBMED:9790910] [PUBMED:10376602] [PUBMED:15247219] [PUBMED:11333271] [PUBMED:12214271] [PUBMED:9804796] [PUBMED:11986311] [PUBMED:9182576] [PUBMED:15217908] [PUBMED:10749680] [PUBMED:16763549]
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation [NCBI:1270120] [REACTOME:R-HSA-1474151] [PUBMED:17555404] [PUBMED:21550412] [PUBMED:10727395] [PUBMED:18321209]
Th17 cell differentiation [NCBI:1469482] [KEGG:hsa04659] [PUBMED:23325835] [PUBMED:23036716] [PUBMED:20488727] [PUBMED:21151104] [PUBMED:21084214] [PUBMED:20054607] [PUBMED:22754770] [PUBMED:22640807] [PUBMED:19379825] [PUBMED:22133865] [PUBMED:22324470] [PUBMED:17768419] [PUBMED:18408735] [PUBMED:21776333] [PUBMED:26253381] [PUBMED:16200068] [PUBMED:18362914] [PUBMED:24325586] [PUBMED:19381306] [PUBMED:18166487]
The role of GTSE1 in G2/M progression after G2 checkpoint [NCBI:1383017] [REACTOME:R-HSA-8852276] [PUBMED:10984615] [PUBMED:9724637] [PUBMED:20577264] [PUBMED:14707141] [PUBMED:23236459] [PUBMED:20018861] [PUBMED:12750368]
Uptake and actions of bacterial toxins [NCBI:1269144] [REACTOME:R-HSA-5339562] [PUBMED:20358680]
Uptake and function of diphtheria toxin [NCBI:1269155] [REACTOME:R-HSA-5336415] [PUBMED:20040] [PUBMED:22069710] [PUBMED:164179]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:17344076] [PUBMED:16633338] [PUBMED:19230644] [PUBMED:13678960]
VEGFR1 specific signals [NCBI:137924] [Pathway Interaction Database:vegfr1_pathway] [PUBMED:9299537] [PUBMED:9751730] [PUBMED:9722576] [PUBMED:14633857] [PUBMED:11978735] [PUBMED:11278319] [PUBMED:12649282] [PUBMED:16839566] [PUBMED:12598525] [PUBMED:12171920] [PUBMED:12796773] [PUBMED:16633338] [PUBMED:11312102] [PUBMED:9295307] [PUBMED:10908731] [PUBMED:16787925] [PUBMED:11704645] [PUBMED:9790910] [PUBMED:10376602] [PUBMED:9804796] [PUBMED:11986311] [PUBMED:10749680] [PUBMED:12214271] [PUBMED:9398617] [PUBMED:8621427] [PUBMED:11425855] [PUBMED:15001553] [PUBMED:10376603] [PUBMED:7824266] [PUBMED:10842181] [PUBMED:9600074]
VEGFR2 mediated vascular permeability [NCBI:1269484] [REACTOME:R-HSA-5218920] [PUBMED:17008595]
Validated targets of C-MYC transcriptional activation [NCBI:169351] [Pathway Interaction Database:myc_activpathway] [PUBMED:18987359] [PUBMED:16537449] [PUBMED:9924025] [PUBMED:17643117] [PUBMED:8356088] [PUBMED:10688915] [PUBMED:1562593] [PUBMED:19020761] [PUBMED:10823814] [PUBMED:12637527] [PUBMED:9178906] [PUBMED:17967894] [PUBMED:15723053] [PUBMED:16508012] [PUBMED:8700224] [PUBMED:12091391] [PUBMED:20173740] [PUBMED:11522645] [PUBMED:15774466] [PUBMED:12776737] [PUBMED:12011429] [PUBMED:12138190] [PUBMED:10022128] [PUBMED:11511539] [PUBMED:12177005] [PUBMED:17599065] [PUBMED:6438521] [PUBMED:19745813] [PUBMED:8196628] [PUBMED:10891489] [PUBMED:8934531] [PUBMED:15723054] [PUBMED:9192621] [PUBMED:18042711] [PUBMED:10779353] [PUBMED:1989881] [PUBMED:8861962] [PUBMED:12529648] [PUBMED:16269333] [PUBMED:16172399] [PUBMED:8494784] [PUBMED:15282543] [PUBMED:8297793] [PUBMED:12776177] [PUBMED:9811896] [PUBMED:11103792] [PUBMED:17170079] [PUBMED:18593934] [PUBMED:11673469] [PUBMED:18408012] [PUBMED:1340466] [PUBMED:17088530] [PUBMED:8327497] [PUBMED:16423995] [PUBMED:12816956] [PUBMED:11598121] [PUBMED:14724288] [PUBMED:17848523] [PUBMED:10508165] [PUBMED:12695333] [PUBMED:17822678] [PUBMED:10606642] [PUBMED:9869632] [PUBMED:9212167] [PUBMED:19211792] [PUBMED:16287840] [PUBMED:18978814] [PUBMED:11511535] [PUBMED:15944709] [PUBMED:11604407] [PUBMED:11909865]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]
eNOS activation [NCBI:1270117] [REACTOME:R-HSA-203615] [PUBMED:10551886] [PUBMED:12482742] [PUBMED:11208594] [PUBMED:16722822]
eNOS activation and regulation [NCBI:1270116] [REACTOME:R-HSA-203765] [PUBMED:12842859] [PUBMED:16722822]
vRNP Assembly [NCBI:1269116] [REACTOME:R-HSA-192905] [PUBMED:3023071] [PUBMED:17081640] [PUBMED:12921991] [PUBMED:6616622]