full name
cytochrome P450 family 19 subfamily A member 1

synonyms
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM, CYP19A1, ENSG00000137869

HGNC
HGNC:2594

Entrez Gene
Gene:1588

ENSEMBL
ENSG00000137869

location
chr: 15
start: 51500254
stop: 51630795
strand: -

OMIM
OMIM:107910: CYP19A1 (Autosomal recessive inheritance)
OMIM:613546: Aromatase deficiency
OMIM:139300: Aromatase excess syndrome

transcripts
NM_000103.3
NM_031226.2

pathways
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [NCBI:413383] [KEGG:hsa_M00110]
Cytochrome P450 - arranged by substrate type [NCBI:1270191] [REACTOME:R-HSA-211897] [PUBMED:16584116] [PUBMED:15102545] [PUBMED:12369887]
Endogenous sterols [NCBI:1270192] [REACTOME:R-HSA-211976] [PUBMED:16872679] [PUBMED:15102545] [PUBMED:16584116]
Estrogen biosynthesis [NCBI:1270051] [REACTOME:R-HSA-193144] [PUBMED:15583024]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Metabolism of steroid hormones [NCBI:1270046] [REACTOME:R-HSA-196071] [PUBMED:15583024]
Ovarian steroidogenesis [NCBI:790011] [KEGG:hsa04913] [PUBMED:11883103] [PUBMED:11408113] [PUBMED:16603089] [PUBMED:15831519] [PUBMED:11447221] [PUBMED:20628033] [PUBMED:10630400] [PUBMED:18440223] [PUBMED:20937107] [PUBMED:11704115] [PUBMED:17003287] [PUBMED:17008391] [PUBMED:15541573] [PUBMED:21862696] [PUBMED:16414178] [PUBMED:14769828]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]
Steroid hormone biosynthesis [NCBI:82940] [KEGG:hsa00140] [PUBMED:15642792] [PUBMED:16413106] [PUBMED:12832414] [PUBMED:17475203] [PUBMED:12604236] [PUBMED:10998348] [PUBMED:11469811] [PUBMED:16547389] [PUBMED:17926129] [PUBMED:17459698]