full name
LEO1 homolog, Paf1/RNA polymerase II complex component

synonyms
RDL, LEO1, ENSG00000166477

HGNC
HGNC:30401

Entrez Gene
Gene:123169

ENSEMBL
ENSG00000166477

location
chr: 15
start: 52230222
stop: 52263995
strand: -

transcripts
NM_138792.2

pathways
E3 ubiquitin ligases ubiquitinate target proteins [NCBI:1470927] [REACTOME:R-HSA-8866654] [PUBMED:23747565] [PUBMED:27312108] [PUBMED:24699078] [PUBMED:19489725] [PUBMED:23912815] [PUBMED:22389392] [PUBMED:17588513] [PUBMED:19436320] [PUBMED:23732108] [PUBMED:19754430] [PUBMED:23624913] [PUBMED:23657496] [PUBMED:26085183]
Formation of RNA Pol II elongation complex [NCBI:1269684] [REACTOME:R-HSA-112382] [PUBMED:12676794]
Formation of the beta-catenin:TCF transactivating complex [NCBI:1269602] [REACTOME:R-HSA-201722] [PUBMED:19305417] [PUBMED:11713476] [PUBMED:18334222] [PUBMED:11934263] [PUBMED:16751178] [PUBMED:22617422] [PUBMED:20951344] [PUBMED:11136974] [PUBMED:19619488] [PUBMED:10831834] [PUBMED:21285352]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Protein ubiquitination [NCBI:1457808] [REACTOME:R-HSA-8852135] [PUBMED:23912815] [PUBMED:17588513] [PUBMED:25175772] [PUBMED:19940261] [PUBMED:19775879] [PUBMED:23624913] [PUBMED:23657496] [PUBMED:23800009] [PUBMED:22708562] [PUBMED:26235645] [PUBMED:25833379] [PUBMED:26187467] [PUBMED:24699078] [PUBMED:26085183] [PUBMED:21883762] [PUBMED:23747565] [PUBMED:27002219] [PUBMED:27312108] [PUBMED:19436320] [PUBMED:23061719] [PUBMED:24457024] [PUBMED:24652853] [PUBMED:23732108] [PUBMED:22389392] [PUBMED:19754430] [PUBMED:19489725] [PUBMED:25815272]
RNA Polymerase II Pre-transcription Events [NCBI:1269676] [REACTOME:R-HSA-674695]
RNA Polymerase II Transcription [NCBI:1269675] [REACTOME:R-HSA-73857]
RNA Polymerase II Transcription Elongation [NCBI:1269682] [REACTOME:R-HSA-75955] [PUBMED:11018013] [PUBMED:12676794] [PUBMED:14550628]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
TCF dependent signaling in response to WNT [NCBI:1269599] [REACTOME:R-HSA-201681] [PUBMED:19619488] [PUBMED:23256519] [PUBMED:23343194]