Home
About
Citations
Statistics
Download
Login
Home
Genes
SMAD3
Gene - SMAD3
full name
SMAD family member 3
synonyms
HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, SMAD3, ENSG00000166949
HGNC
HGNC:6769
Entrez Gene
Gene:4088
ENSEMBL
ENSG00000166949
location
chr: 15
start: 67358036
stop: 67487533
strand: +
OMIM
OMIM:603109
: SMAD3
(Autosomal dominant inheritance)
OMIM:613795
: Loeys-Dietz syndrome 3
transcripts
NM_005902.3
NM_001145102.1
NM_001145103.1
NM_001145104.1
pathways
AGE-RAGE signaling pathway in diabetic complications
[NCBI:1319988]
[KEGG:hsa04933]
[PUBMED:23776698]
[PUBMED:15569303]
[PUBMED:16894049]
[PUBMED:18323529]
[PUBMED:11375353]
[PUBMED:21111800]
[PUBMED:19404313]
[PUBMED:20470857]
[PUBMED:17005604]
[PUBMED:23961320]
[PUBMED:21261520]
[PUBMED:11180401]
[PUBMED:18922799]
[PUBMED:21680901]
[PUBMED:11684565]
[PUBMED:21590515]
[PUBMED:12709399]
[PUBMED:20300563]
[PUBMED:21440603]
[PUBMED:22558488]
Adherens junction
[NCBI:83070]
[KEGG:hsa04520]
[PUBMED:11703922]
[PUBMED:10890911]
[PUBMED:15551862]
[PUBMED:15561584]
[PUBMED:10959047]
[PUBMED:11984870]
[PUBMED:10204118]
[PUBMED:15489912]
[PUBMED:14623871]
[PUBMED:15001769]
[PUBMED:12640114]
[PUBMED:12665527]
[PUBMED:11171368]
Apelin signaling pathway
[NCBI:1492886]
[KEGG:hsa04371]
[PUBMED:23973488]
[PUBMED:16182514]
[PUBMED:21725702]
[PUBMED:22842084]
[PUBMED:27825851]
[PUBMED:27650065]
[PUBMED:22140623]
[PUBMED:23943882]
[PUBMED:26944568]
[PUBMED:24055369]
[PUBMED:26385179]
[PUBMED:26143239]
[PUBMED:22028387]
[PUBMED:26254105]
[PUBMED:26756969]
[PUBMED:22995518]
[PUBMED:27979574]
[PUBMED:23924696]
[PUBMED:21464822]
[PUBMED:25914650]
[PUBMED:24990699]
[PUBMED:26607438]
[PUBMED:25164121]
[PUBMED:25275559]
[PUBMED:25139773]
[PUBMED:25931124]
[PUBMED:19093215]
[PUBMED:20539939]
[PUBMED:25652330]
[PUBMED:18272138]
[PUBMED:23603510]
Cell cycle
[NCBI:83054]
[KEGG:hsa04110]
[PUBMED:7973727]
[PUBMED:17568790]
[PUBMED:9832503]
[PUBMED:16936746]
[PUBMED:9029154]
[PUBMED:12573239]
[PUBMED:19020303]
[PUBMED:9618481]
[PUBMED:12809600]
[PUBMED:8242749]
[PUBMED:10385618]
[PUBMED:17426725]
[PUBMED:17018296]
[PUBMED:16212951]
[PUBMED:12925736]
[PUBMED:11099028]
[PUBMED:15568976]
[PUBMED:15838516]
[PUBMED:15838523]
[PUBMED:15876871]
[PUBMED:7908906]
[PUBMED:9889196]
Chagas disease (American trypanosomiasis)
[NCBI:147809]
[KEGG:hsa05142]
[PUBMED:12377585]
[PUBMED:9794425]
[PUBMED:1717552]
[PUBMED:16238097]
[PUBMED:10066513]
[PUBMED:12874238]
[PUBMED:12036740]
[PUBMED:15917295]
[PUBMED:12055254]
[PUBMED:17651955]
[PUBMED:1396957]
[PUBMED:16175174]
[PUBMED:2194668]
[PUBMED:9190942]
[PUBMED:12377942]
[PUBMED:12427093]
[PUBMED:10234174]
[PUBMED:16030288]
[PUBMED:15223603]
[PUBMED:17110955]
Chronic myeloid leukemia
[NCBI:83116]
[KEGG:hsa05220]
[PUBMED:22286129]
[PUBMED:12801837]
[PUBMED:11160144]
[PUBMED:15719031]
[PUBMED:10403855]
[PUBMED:9834202]
[PUBMED:11071626]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16484590]
[PUBMED:14982876]
Colorectal cancer
[NCBI:83106]
[KEGG:hsa05210]
[PUBMED:15479695]
[PUBMED:11459867]
[PUBMED:9196022]
[PUBMED:11170304]
[PUBMED:12951588]
[PUBMED:15349822]
[PUBMED:15711891]
[PUBMED:16042571]
[PUBMED:15000146]
[PUBMED:12737309]
[PUBMED:10505543]
[PUBMED:11078609]
[PUBMED:11223406]
[PUBMED:16326109]
[PUBMED:16699851]
[PUBMED:11477132]
[PUBMED:12621137]
[PUBMED:15573119]
[PUBMED:16555243]
[PUBMED:15310786]
Deubiquitination
[NCBI:1427860]
[REACTOME:R-HSA-5688426]
[PUBMED:19243136]
[PUBMED:20074029]
[PUBMED:15571815]
[PUBMED:20418328]
[PUBMED:16325574]
[PUBMED:12944365]
[PUBMED:23845989]
[PUBMED:22201797]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
Downregulation of SMAD2/3:SMAD4 transcriptional activity
[NCBI:1269529]
[REACTOME:R-HSA-2173795]
[PUBMED:19917253]
[PUBMED:11389444]
[PUBMED:10535941]
[PUBMED:10199400]
[PUBMED:16751101]
[PUBMED:17591695]
[PUBMED:10485843]
[PUBMED:21095583]
[PUBMED:11427533]
[PUBMED:19135894]
[PUBMED:10531062]
[PUBMED:22045334]
[PUBMED:10549282]
Downregulation of TGF-beta receptor signaling
[NCBI:1269525]
[REACTOME:R-HSA-2173788]
[PUBMED:10519551]
[PUBMED:16027725]
[PUBMED:9215638]
[PUBMED:20937913]
[PUBMED:20129061]
[PUBMED:11158580]
[PUBMED:9335507]
[PUBMED:15781469]
[PUBMED:12519765]
[PUBMED:16061177]
[PUBMED:10757800]
[PUBMED:11278251]
[PUBMED:12151385]
[PUBMED:20061380]
[PUBMED:22045334]
[PUBMED:14701756]
[PUBMED:15496141]
[PUBMED:19758997]
[PUBMED:14718519]
[PUBMED:22344298]
[PUBMED:11163210]
Endocytosis
[NCBI:102279]
[KEGG:hsa04144]
[PUBMED:19696797]
[PUBMED:19007773]
[PUBMED:16203612]
[PUBMED:15687999]
[PUBMED:19924646]
[PUBMED:15261671]
[PUBMED:18647649]
[PUBMED:19325624]
[PUBMED:20110990]
[PUBMED:22193161]
FoxO signaling pathway
[NCBI:921162]
[KEGG:hsa04068]
[PUBMED:23325358]
[PUBMED:15005655]
[PUBMED:18951090]
[PUBMED:22761423]
[PUBMED:22902436]
[PUBMED:16288288]
[PUBMED:19701188]
[PUBMED:16964248]
[PUBMED:18045156]
[PUBMED:18403263]
[PUBMED:21613825]
[PUBMED:21440011]
[PUBMED:17470511]
[PUBMED:21238503]
[PUBMED:17522590]
[PUBMED:15084259]
[PUBMED:23801966]
[PUBMED:17569704]
[PUBMED:15516968]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
HIF-1-alpha transcription factor network
[NCBI:138045]
[Pathway Interaction Database:hif1_tfpathway]
[PUBMED:11707426]
[PUBMED:9242677]
[PUBMED:9038135]
[PUBMED:15310764]
[PUBMED:11278891]
[PUBMED:8816435]
[PUBMED:8663540]
[PUBMED:15235127]
[PUBMED:12042299]
[PUBMED:15312748]
[PUBMED:14612449]
[PUBMED:11342587]
[PUBMED:12615703]
[PUBMED:9632793]
[PUBMED:12228247]
[PUBMED:15044468]
[PUBMED:8408001]
[PUBMED:9822602]
[PUBMED:15252039]
[PUBMED:13679920]
[PUBMED:11877282]
[PUBMED:15235597]
[PUBMED:15199161]
[PUBMED:15104534]
[PUBMED:10594042]
[PUBMED:12354771]
[PUBMED:10446188]
[PUBMED:9436976]
[PUBMED:11823643]
[PUBMED:12370277]
[PUBMED:8955077]
[PUBMED:12879018]
[PUBMED:14645546]
[PUBMED:9486205]
[PUBMED:9887100]
[PUBMED:8089148]
[PUBMED:15466858]
[PUBMED:11708773]
[PUBMED:15611046]
[PUBMED:14742449]
[PUBMED:15280364]
[PUBMED:12215445]
[PUBMED:15611089]
[PUBMED:10777486]
[PUBMED:9707622]
[PUBMED:8917528]
[PUBMED:15563275]
[PUBMED:12067980]
[PUBMED:10353251]
HTLV-I infection
[NCBI:373901]
[KEGG:hsa05166]
[PUBMED:17446673]
[PUBMED:16436385]
[PUBMED:14686485]
[PUBMED:19861996]
[PUBMED:19092975]
[PUBMED:11325603]
[PUBMED:16155602]
[PUBMED:12910251]
[PUBMED:16155605]
[PUBMED:16036567]
[PUBMED:11244044]
[PUBMED:18702816]
[PUBMED:15569630]
[PUBMED:21114861]
[PUBMED:16155611]
[PUBMED:17384582]
[PUBMED:16155608]
[PUBMED:10602469]
[PUBMED:19014483]
[PUBMED:9325311]
Hepatitis B
[NCBI:694606]
[KEGG:hsa05161]
[PUBMED:19854353]
[PUBMED:11604508]
[PUBMED:11325602]
[PUBMED:18931690]
[PUBMED:16891440]
[PUBMED:17158882]
[PUBMED:11099494]
[PUBMED:9325306]
[PUBMED:18024894]
[PUBMED:11483993]
[PUBMED:15107488]
[PUBMED:11278872]
[PUBMED:21647825]
[PUBMED:11287574]
[PUBMED:18481805]
[PUBMED:17188775]
[PUBMED:19784739]
[PUBMED:19263472]
[PUBMED:16203685]
[PUBMED:18605975]
[PUBMED:10454581]
[PUBMED:22504921]
[PUBMED:21334391]
[PUBMED:20657822]
[PUBMED:18046710]
[PUBMED:9843511]
[PUBMED:15542625]
[PUBMED:21618535]
[PUBMED:15132991]
[PUBMED:15173177]
[PUBMED:12771941]
[PUBMED:21994545]
[PUBMED:8764004]
[PUBMED:16459163]
[PUBMED:9738022]
[PUBMED:11821950]
[PUBMED:12839924]
Hippo signaling pathway
[NCBI:749777]
[KEGG:hsa04390]
[PUBMED:18955139]
[PUBMED:20439427]
[PUBMED:20951342]
[PUBMED:21138973]
[PUBMED:18328423]
[PUBMED:21324984]
[PUBMED:23034192]
[PUBMED:21808241]
[PUBMED:17975546]
[PUBMED:22750148]
[PUBMED:21084559]
[PUBMED:19846288]
[PUBMED:22895435]
[PUBMED:22683405]
[PUBMED:22658639]
[PUBMED:22153608]
[PUBMED:20945341]
[PUBMED:22830020]
[PUBMED:21874053]
[PUBMED:21376238]
Inflammatory bowel disease (IBD)
[NCBI:842771]
[KEGG:hsa05321]
[PUBMED:17499605]
[PUBMED:12006974]
[PUBMED:18053739]
[PUBMED:20134493]
[PUBMED:10898785]
[PUBMED:18563156]
[PUBMED:23176791]
[PUBMED:18200661]
[PUBMED:12797537]
[PUBMED:21487504]
[PUBMED:19381306]
[PUBMED:21681604]
[PUBMED:19322214]
[PUBMED:16493424]
[PUBMED:18242222]
[PUBMED:12042806]
[PUBMED:9759857]
Loss of Function of SMAD2/3 in Cancer
[NCBI:1268897]
[REACTOME:R-HSA-3304349]
[PUBMED:15350224]
[PUBMED:12183405]
[PUBMED:9753318]
[PUBMED:12384562]
[PUBMED:11224571]
[PUBMED:23139211]
Loss of Function of SMAD4 in Cancer
[NCBI:1268895]
[REACTOME:R-HSA-3304347]
[PUBMED:10773876]
[PUBMED:9582123]
[PUBMED:20952405]
[PUBMED:9214507]
[PUBMED:9990040]
[PUBMED:10436786]
[PUBMED:9214508]
[PUBMED:8553070]
[PUBMED:23139211]
[PUBMED:9506519]
Loss of Function of TGFBR1 in Cancer
[NCBI:1268903]
[REACTOME:R-HSA-3656534]
[PUBMED:11406536]
[PUBMED:11477574]
[PUBMED:19147584]
[PUBMED:21358634]
[PUBMED:9850059]
[PUBMED:9809982]
[PUBMED:10515889]
Metabolism of proteins
[NCBI:1268677]
[REACTOME:R-HSA-392499]
Pancreatic cancer
[NCBI:83108]
[KEGG:hsa05212]
[PUBMED:12079267]
[PUBMED:14967450]
[PUBMED:15774796]
[PUBMED:10740269]
[PUBMED:12946833]
[PUBMED:16702400]
[PUBMED:14586404]
[PUBMED:15823750]
[PUBMED:12648469]
[PUBMED:11407945]
[PUBMED:12459728]
[PUBMED:14580692]
[PUBMED:11707511]
[PUBMED:12545153]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Post-translational protein modification
[NCBI:1268701]
[REACTOME:R-HSA-597592]
Regulation of Telomerase
[NCBI:137987]
[Pathway Interaction Database:telomerasepathway]
[PUBMED:12037663]
[PUBMED:11191110]
[PUBMED:15381700]
[PUBMED:10637317]
[PUBMED:15314656]
[PUBMED:10601322]
[PUBMED:12545159]
[PUBMED:11110707]
[PUBMED:15371341]
[PUBMED:12681489]
[PUBMED:15824061]
[PUBMED:15048073]
[PUBMED:10850490]
[PUBMED:16730176]
[PUBMED:12181313]
[PUBMED:16890531]
[PUBMED:9837921]
[PUBMED:10224060]
[PUBMED:15331176]
[PUBMED:16522649]
[PUBMED:9822378]
[PUBMED:15316005]
[PUBMED:12699629]
[PUBMED:16843438]
[PUBMED:12151407]
[PUBMED:12135483]
[PUBMED:15655249]
[PUBMED:10888888]
[PUBMED:16765199]
[PUBMED:16869756]
[PUBMED:10837221]
[PUBMED:16135795]
[PUBMED:11074006]
[PUBMED:11191109]
[PUBMED:14712220]
[PUBMED:16508638]
[PUBMED:10471503]
[PUBMED:11854288]
[PUBMED:16785237]
[PUBMED:9130722]
[PUBMED:12956959]
[PUBMED:15710386]
[PUBMED:12586360]
[PUBMED:12377759]
[PUBMED:11433024]
[PUBMED:15843522]
[PUBMED:14749375]
[PUBMED:11274138]
[PUBMED:12676087]
[PUBMED:16166375]
[PUBMED:15371412]
Regulation of cytoplasmic and nuclear SMAD2/3 signaling
[NCBI:138015]
[Pathway Interaction Database:smad2_3pathway]
[PUBMED:8893010]
[PUBMED:12740389]
[PUBMED:12193595]
[PUBMED:11294908]
[PUBMED:10085121]
[PUBMED:9620846]
[PUBMED:12592392]
[PUBMED:14750902]
[PUBMED:12917407]
[PUBMED:12374795]
[PUBMED:16751101]
[PUBMED:9346908]
[PUBMED:10197981]
[PUBMED:12621041]
[PUBMED:9214508]
[PUBMED:11278302]
[PUBMED:17035229]
[PUBMED:12191473]
Regulation of nuclear SMAD2/3 signaling
[NCBI:137963]
[Pathway Interaction Database:smad2_3nuclearpathway]
[PUBMED:15009097]
[PUBMED:11790301]
[PUBMED:11836524]
[PUBMED:10995736]
[PUBMED:11114293]
[PUBMED:10973944]
[PUBMED:10022869]
[PUBMED:11058129]
[PUBMED:9722503]
[PUBMED:12904571]
[PUBMED:14993291]
[PUBMED:11013220]
[PUBMED:15363409]
[PUBMED:9702197]
[PUBMED:12718878]
[PUBMED:11331591]
[PUBMED:12167862]
[PUBMED:14729983]
[PUBMED:9707553]
[PUBMED:10878024]
[PUBMED:9679060]
[PUBMED:10887155]
[PUBMED:10199400]
[PUBMED:12631740]
[PUBMED:11555647]
[PUBMED:15688032]
[PUBMED:12150994]
[PUBMED:12374795]
[PUBMED:9606191]
[PUBMED:9702198]
[PUBMED:10518526]
[PUBMED:10575014]
[PUBMED:10485843]
[PUBMED:11283614]
[PUBMED:10722728]
[PUBMED:10037600]
[PUBMED:15241418]
[PUBMED:14691252]
[PUBMED:10748032]
[PUBMED:12551947]
[PUBMED:14671321]
[PUBMED:11427533]
[PUBMED:11711431]
[PUBMED:10531362]
[PUBMED:11571228]
[PUBMED:10085140]
[PUBMED:17478422]
[PUBMED:15044954]
[PUBMED:10964912]
[PUBMED:11707452]
[PUBMED:11801598]
[PUBMED:17074756]
[PUBMED:12226080]
[PUBMED:10557285]
[PUBMED:10843994]
[PUBMED:15084259]
[PUBMED:10531062]
[PUBMED:16959612]
[PUBMED:9679056]
[PUBMED:10652350]
[PUBMED:9618481]
[PUBMED:11927558]
[PUBMED:9732876]
SMAD2/3 MH2 Domain Mutants in Cancer
[NCBI:1268899]
[REACTOME:R-HSA-3315487]
[PUBMED:23139211]
SMAD2/3 Phosphorylation Motif Mutants in Cancer
[NCBI:1268898]
[REACTOME:R-HSA-3304356]
[PUBMED:11224571]
[PUBMED:8980228]
[PUBMED:9311995]
[PUBMED:23139211]
[PUBMED:9346966]
[PUBMED:15350224]
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
[NCBI:1269528]
[REACTOME:R-HSA-2173796]
[PUBMED:22275377]
[PUBMED:18568018]
[PUBMED:15150273]
[PUBMED:10934479]
[PUBMED:11294908]
[PUBMED:12592392]
[PUBMED:10022869]
[PUBMED:14657019]
[PUBMED:11013220]
[PUBMED:11274402]
[PUBMED:19914168]
[PUBMED:12150994]
SMAD4 MH2 Domain Mutants in Cancer
[NCBI:1268896]
[REACTOME:R-HSA-3311021]
[PUBMED:9214508]
[PUBMED:11224571]
[PUBMED:23139211]
[PUBMED:15350224]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Activin
[NCBI:1269621]
[REACTOME:R-HSA-1502540]
[PUBMED:8622651]
[PUBMED:16636301]
[PUBMED:22651914]
[PUBMED:8721982]
Signaling by NODAL
[NCBI:1270343]
[REACTOME:R-HSA-1181150]
[PUBMED:17287255]
[PUBMED:20066122]
Signaling by TGF-beta Receptor Complex
[NCBI:1269523]
[REACTOME:R-HSA-170834]
[PUBMED:19648010]
Signaling by TGF-beta Receptor Complex in Cancer
[NCBI:1268894]
[REACTOME:R-HSA-3304351]
[PUBMED:9214508]
[PUBMED:7664267]
[PUBMED:8553070]
[PUBMED:8752208]
[PUBMED:21358634]
[PUBMED:7777546]
[PUBMED:23139211]
[PUBMED:8078588]
[PUBMED:19834456]
[PUBMED:9809982]
[PUBMED:22710176]
[PUBMED:7761852]
[PUBMED:9927040]
[PUBMED:17936557]
[PUBMED:12150994]
[PUBMED:11406536]
[PUBMED:2418960]
[PUBMED:7585632]
[PUBMED:11477574]
Signaling pathways regulating pluripotency of stem cells
[NCBI:1026136]
[KEGG:hsa04550]
[PUBMED:20705693]
[PUBMED:23653415]
[PUBMED:16518401]
[PUBMED:17211451]
[PUBMED:22649650]
[PUBMED:24910449]
[PUBMED:19551525]
[PUBMED:22298652]
[PUBMED:23370346]
[PUBMED:24315442]
[PUBMED:18414030]
[PUBMED:17647265]
[PUBMED:18295576]
[PUBMED:24957798]
[PUBMED:24147644]
[PUBMED:16153702]
[PUBMED:19427042]
[PUBMED:18220859]
[PUBMED:19571885]
[PUBMED:23585347]
TGF-beta receptor signaling
[NCBI:138024]
[Pathway Interaction Database:tgfbrpathway]
[PUBMED:12118366]
[PUBMED:8242743]
[PUBMED:15221015]
[PUBMED:9335507]
[PUBMED:11278302]
[PUBMED:16601693]
[PUBMED:8391934]
[PUBMED:1333888]
[PUBMED:11438668]
[PUBMED:17327236]
[PUBMED:2879635]
[PUBMED:11483955]
[PUBMED:12717440]
[PUBMED:8047140]
[PUBMED:8576253]
[PUBMED:9865696]
[PUBMED:9346908]
[PUBMED:17197390]
[PUBMED:8533096]
[PUBMED:8756725]
[PUBMED:10615055]
[PUBMED:10934479]
[PUBMED:16251192]
[PUBMED:7706248]
[PUBMED:15946939]
[PUBMED:7774578]
[PUBMED:7988555]
[PUBMED:11278251]
[PUBMED:11027280]
[PUBMED:17420258]
[PUBMED:9169454]
[PUBMED:12151385]
[PUBMED:10757800]
[PUBMED:12543979]
[PUBMED:12475967]
[PUBMED:9679059]
[PUBMED:17673906]
[PUBMED:9774674]
[PUBMED:8893010]
[PUBMED:1544886]
[PUBMED:12958365]
[PUBMED:12110587]
[PUBMED:9233797]
[PUBMED:11163210]
[PUBMED:15496141]
[PUBMED:7693660]
[PUBMED:14657019]
[PUBMED:12429842]
[PUBMED:11124802]
[PUBMED:11389444]
[PUBMED:8798398]
[PUBMED:15356634]
[PUBMED:17272273]
[PUBMED:1657407]
[PUBMED:12589052]
[PUBMED:11016919]
[PUBMED:14718519]
[PUBMED:10777621]
[PUBMED:17384642]
[PUBMED:1310899]
[PUBMED:9856985]
[PUBMED:10519551]
[PUBMED:9155023]
[PUBMED:12134160]
[PUBMED:9215638]
[PUBMED:12134149]
[PUBMED:16157589]
[PUBMED:12356868]
[PUBMED:11387212]
[PUBMED:12034739]
[PUBMED:11739411]
[PUBMED:15761148]
[PUBMED:9463378]
[PUBMED:11583628]
[PUBMED:15684397]
[PUBMED:8947046]
[PUBMED:11781097]
TGF-beta receptor signaling activates SMADs
[NCBI:1269524]
[REACTOME:R-HSA-2173789]
[PUBMED:9346966]
[PUBMED:15350224]
[PUBMED:7737999]
[PUBMED:11100470]
[PUBMED:7693660]
[PUBMED:9670020]
[PUBMED:15564041]
[PUBMED:9233797]
[PUBMED:20207738]
[PUBMED:11779505]
[PUBMED:18243111]
[PUBMED:8947046]
[PUBMED:1333888]
[PUBMED:9311995]
[PUBMED:12482908]
[PUBMED:8980228]
[PUBMED:8242743]
[PUBMED:9865696]
[PUBMED:8047140]
[PUBMED:21423151]
TGF-beta signaling pathway
[NCBI:83064]
[KEGG:hsa04350]
[PUBMED:11836504]
[PUBMED:14534577]
[PUBMED:10021351]
[PUBMED:12809600]
[PUBMED:14557817]
[PUBMED:14769828]
[PUBMED:10519551]
[PUBMED:12163231]
[PUBMED:19758997]
[PUBMED:12466190]
[PUBMED:11252746]
[PUBMED:15063168]
[PUBMED:9847239]
[PUBMED:11252892]
TGFBR1 KD Mutants in Cancer
[NCBI:1268905]
[REACTOME:R-HSA-3656532]
[PUBMED:11406536]
[PUBMED:11477574]
[PUBMED:21358634]
[PUBMED:9809982]
Th17 cell differentiation
[NCBI:1469482]
[KEGG:hsa04659]
[PUBMED:23325835]
[PUBMED:23036716]
[PUBMED:20488727]
[PUBMED:21151104]
[PUBMED:21084214]
[PUBMED:20054607]
[PUBMED:22754770]
[PUBMED:22640807]
[PUBMED:19379825]
[PUBMED:22133865]
[PUBMED:22324470]
[PUBMED:17768419]
[PUBMED:18408735]
[PUBMED:21776333]
[PUBMED:26253381]
[PUBMED:16200068]
[PUBMED:18362914]
[PUBMED:24325586]
[PUBMED:19381306]
[PUBMED:18166487]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
[NCBI:1269527]
[REACTOME:R-HSA-2173793]
[PUBMED:12150994]
[PUBMED:16751101]
[PUBMED:10199400]
[PUBMED:18568018]
[PUBMED:19135894]
[PUBMED:10531062]
Ub-specific processing proteases
[NCBI:1427862]
[REACTOME:R-HSA-5689880]
[PUBMED:16325574]
Validated targets of C-MYC transcriptional activation
[NCBI:169351]
[Pathway Interaction Database:myc_activpathway]
[PUBMED:18987359]
[PUBMED:16537449]
[PUBMED:9924025]
[PUBMED:17643117]
[PUBMED:8356088]
[PUBMED:10688915]
[PUBMED:1562593]
[PUBMED:19020761]
[PUBMED:10823814]
[PUBMED:12637527]
[PUBMED:9178906]
[PUBMED:17967894]
[PUBMED:15723053]
[PUBMED:16508012]
[PUBMED:8700224]
[PUBMED:12091391]
[PUBMED:20173740]
[PUBMED:11522645]
[PUBMED:15774466]
[PUBMED:12776737]
[PUBMED:12011429]
[PUBMED:12138190]
[PUBMED:10022128]
[PUBMED:11511539]
[PUBMED:12177005]
[PUBMED:17599065]
[PUBMED:6438521]
[PUBMED:19745813]
[PUBMED:8196628]
[PUBMED:10891489]
[PUBMED:8934531]
[PUBMED:15723054]
[PUBMED:9192621]
[PUBMED:18042711]
[PUBMED:10779353]
[PUBMED:1989881]
[PUBMED:8861962]
[PUBMED:12529648]
[PUBMED:16269333]
[PUBMED:16172399]
[PUBMED:8494784]
[PUBMED:15282543]
[PUBMED:8297793]
[PUBMED:12776177]
[PUBMED:9811896]
[PUBMED:11103792]
[PUBMED:17170079]
[PUBMED:18593934]
[PUBMED:11673469]
[PUBMED:18408012]
[PUBMED:1340466]
[PUBMED:17088530]
[PUBMED:8327497]
[PUBMED:16423995]
[PUBMED:12816956]
[PUBMED:11598121]
[PUBMED:14724288]
[PUBMED:17848523]
[PUBMED:10508165]
[PUBMED:12695333]
[PUBMED:17822678]
[PUBMED:10606642]
[PUBMED:9869632]
[PUBMED:9212167]
[PUBMED:19211792]
[PUBMED:16287840]
[PUBMED:18978814]
[PUBMED:11511535]
[PUBMED:15944709]
[PUBMED:11604407]
[PUBMED:11909865]
Wnt signaling pathway
[NCBI:83061]
[KEGG:hsa04310]
[PUBMED:12446114]
[PUBMED:14745971]
[PUBMED:14530294]
[PUBMED:15102436]
[PUBMED:14635791]
[PUBMED:19482104]
[PUBMED:23256519]
[PUBMED:12967557]
[PUBMED:11433294]
[PUBMED:18838381]